Basic Information

Insect: Formica selysi
Gene Symbol: Zeb1
Assembly: GCA_009859135.1
Location: CM020805.1:10324212-10329717[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.022 3.6 9.0 0.6 1 23 358 381 358 381 0.91

2 14 3.4e-05 0.0056 17.9 1.4 1 23 387 409 387 409 0.98

3 14 0.073 12 7.4 5.3 1 23 493 515 493 515 0.93

4 14 0.0034 0.57 11.6 0.4 1 23 522 545 522 545 0.91

5 14 0.00054 0.09 14.1 4.4 1 23 551 573 551 573 0.97

6 14 0.00081 0.13 13.5 2.2 1 23 579 601 579 601 0.99

7 14 1.1e-06 0.00018 22.6 1.2 1 23 607 629 607 629 0.98

8 14 0.053 8.8 7.8 0.2 1 23 642 665 642 665 0.93

9 14 9.3e-05 0.015 16.5 4.3 1 23 681 704 681 704 0.96

10 14 0.00023 0.038 15.2 0.5 1 23 712 735 712 735 0.98

11 14 2.2e-05 0.0036 18.5 0.5 1 23 741 763 741 763 0.98

12 14 0.0027 0.44 11.9 8.5 1 23 769 791 769 791 0.98

13 14 2.3e-05 0.0039 18.4 3.0 1 23 797 820 797 820 0.98

14 14 0.0005 0.083 14.2 0.5 2 23 826 847 825 847 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.022	3.6	9.0	0.6	1	23	358	381	358	381	0.91
2	14	3.4e-05	0.0056	17.9	1.4	1	23	387	409	387	409	0.98
3	14	0.073	12	7.4	5.3	1	23	493	515	493	515	0.93
4	14	0.0034	0.57	11.6	0.4	1	23	522	545	522	545	0.91
5	14	0.00054	0.09	14.1	4.4	1	23	551	573	551	573	0.97
6	14	0.00081	0.13	13.5	2.2	1	23	579	601	579	601	0.99
7	14	1.1e-06	0.00018	22.6	1.2	1	23	607	629	607	629	0.98
8	14	0.053	8.8	7.8	0.2	1	23	642	665	642	665	0.93
9	14	9.3e-05	0.015	16.5	4.3	1	23	681	704	681	704	0.96
10	14	0.00023	0.038	15.2	0.5	1	23	712	735	712	735	0.98
11	14	2.2e-05	0.0036	18.5	0.5	1	23	741	763	741	763	0.98
12	14	0.0027	0.44	11.9	8.5	1	23	769	791	769	791	0.98
13	14	2.3e-05	0.0039	18.4	3.0	1	23	797	820	797	820	0.98
14	14	0.0005	0.083	14.2	0.5	2	23	826	847	825	847	0.97

Sequence Information

Coding Sequence: atgtcaaatgATTCATTGATATGTCGTTTGTGTGGTATTAAACATGAACTtacaaattcaaaatatatctttgatgAGACAACTAATTtaactcaaaaaataaatgacaCACTACCAATCAGGATTTCGCAGGATGATCATTCCAAATACATATGCTTGAACTGCTACGAAAAAGTTACTACTCATTATGATTTTATCCAAAATGTATTGGAAAATTCAAAGGAGAACGTTAATATGGCAAAAAGTAATTCTTCATTTGAGCCcaataaaagtgaaaaaatgGAAATTGCAGCAATTTCCAAACTATATAatgatatgatatatacatgCCCAAATTGCAATATAGATTTAATGATACTAATAAAAAGCAATCCTGATGATTGTAATTATGCATTTCAAATTTCATTGGCCATAGTAGACCAAATGGAAAAATCAATGGAAAGAAATATCCAAACCTGTGATGATGCAATAGAATTTGTTAATACTTGCATAAAAACATCAAGTATAGAAGATGATTTGCATGAATCATCATTGAATCAGAGTATTATCAACGATACATTAAATGATAAGGAACAAAACATCAATAAAACAGATGAAAAGTTACCAATACTACAAGAAGATATAAATCATGTTGACACTTGCATtacatttcaaaaaaataatgtatcacATCGATTGAGCAAAGGTACAAAAAGAAAACTTaaggaaaatatttcttgtgAAACACCTACTAAATCACAAAAACTAGAAACGAAGTTAGATGCAACAGACACTAATGTATTGGACAATGATTATGGGTGTGTAGATATCTTGATAAAAGATGAGAATCTAAATGATGGAATAGATGAAGGTGTCGAATGGCTTAGTGGTGAAATAAACTTCAAAGAAGAGAATACTACAGTGTATACAATAGAAGCTGAAAAAGATCACATTGATGAAAATGGTATAAAATACGACGATATCGACAGTAAGAGTccaaaaattgtatgtaatTTATGTGGAGCTCGTTATCTTTCTCAATTAAAATACGAGTTTCACATGGAGAGGCACAAGTCAAACAAAATGGATAGATATGTCTGCACAGTATGTGACAAAGAAGCTAGCAGTGAGAACTTATTGTGGGATCACTATTTCCATACACATAAAAGCTCGATGCGGTATGCTTGCACACAATGCGGCAAGATGTTTACGAAGAAACCGAGATTAAATGGTCACCAAAAGAGACATAAACACTTCGGTATCAAAGAGATACATTTTGAGATGGGCATGGATGAAATAAGCGTCAATCAAGCACAGAAAGCTATCGCGGTCGAAATACAAGGACGAGTTGCCGCAAATTGTAGTCTCTGTGGaaaattaataacagattTAGATCCGGATGCTATCAACGATTTGGCGACATGCGCGGCCTGCGAGGATTCCACTTTATCGCTGATGGTCGATGGAAACGAAATGAAAGTGATCTCGCCGCGGCAGTACCATTGCTCAAAATGCCCTAAACATTTTGTGCGCAAAGAGAGACTGGAGTTTCATGAGATGAGACATAATGAAAACATGAACGAATTTATCTGCAGCACATGTGGCAAGGAGTTTAGTGCAGAAAACTCCTTGTATGAGCATTATCTCTTTGTACACAAAGGAGCTAGGCCACATATCTGTGAGCAATGCGGCAAGTCGTTTCAGTTGAAGGCACGATTGAAAGAACATCATCGCACGCATACAGGTGAAAGACCTTATCAATGCGACGTATGCGGTCTACGCTGCATGACTACCAATGCGCTCAAACTCCACAGGAAAACTCATTTCTCTCACAATCGCTATGTTTGTAATATATGTGACAAATCCTTCAGCAAAAAACAGAACATGAACGAGCATTTGGAAAAGCACTGGAAAAACGATAAGAATGTATCGCTGCCGCAATTGTTTACATGTCCGGTATGTACCGAAGATTTGCCGACCTATCGTATGCTAAAGTATCACTTGATCGACACTCATAAGATCGATCGCCAAGATCCCTTACTAACAACACAAAAACCATGGTACGAATGCAACGAATGTCATGAAAAGTTCAAACATCAAATGTCGCTGAAGGCGCACAAAGAAAAAGTACACGAGGGTAAGGTCAGCCCAATATTCCAGTGCGATATATGTAACGCTACTTACAGAATCAAGCAGCTGCTGATAAATCACATCAAAAGCAAGCATGGTGGTGAAAAGCGATACAAATGTGCGCAATGTGGCAAAGGATTCAATGATACCAAATCCTTGTACAATCACATTTTATTACACACTGGTAGGAAGCCATTCACTTGTGAATACTGTCACATGAGCTTCAGGCGAAAAGACTCCAGGGACCACCATCGCCGTAAGCATACAGGCGAACAGCCTTACCAGTGCTCGGATTGCGGACAATCGTTTTCTACCTACAACAATCGCTCAAAGCATCGCAAGAAGGAACATGGAGAAGGTGAAATCGAATGTCCAGAGTGTGGAGAAAAATGTAACAGTCAACAAGAAATCAGAATTCATCTGAACAAGCATCTTGGTGAAAAATTGAATAACTTACAACGTGTATAA
Protein Sequence: MSNDSLICRLCGIKHELTNSKYIFDETTNLTQKINDTLPIRISQDDHSKYICLNCYEKVTTHYDFIQNVLENSKENVNMAKSNSSFEPNKSEKMEIAAISKLYNDMIYTCPNCNIDLMILIKSNPDDCNYAFQISLAIVDQMEKSMERNIQTCDDAIEFVNTCIKTSSIEDDLHESSLNQSIINDTLNDKEQNINKTDEKLPILQEDINHVDTCITFQKNNVSHRLSKGTKRKLKENISCETPTKSQKLETKLDATDTNVLDNDYGCVDILIKDENLNDGIDEGVEWLSGEINFKEENTTVYTIEAEKDHIDENGIKYDDIDSKSPKIVCNLCGARYLSQLKYEFHMERHKSNKMDRYVCTVCDKEASSENLLWDHYFHTHKSSMRYACTQCGKMFTKKPRLNGHQKRHKHFGIKEIHFEMGMDEISVNQAQKAIAVEIQGRVAANCSLCGKLITDLDPDAINDLATCAACEDSTLSLMVDGNEMKVISPRQYHCSKCPKHFVRKERLEFHEMRHNENMNEFICSTCGKEFSAENSLYEHYLFVHKGARPHICEQCGKSFQLKARLKEHHRTHTGERPYQCDVCGLRCMTTNALKLHRKTHFSHNRYVCNICDKSFSKKQNMNEHLEKHWKNDKNVSLPQLFTCPVCTEDLPTYRMLKYHLIDTHKIDRQDPLLTTQKPWYECNECHEKFKHQMSLKAHKEKVHEGKVSPIFQCDICNATYRIKQLLINHIKSKHGGEKRYKCAQCGKGFNDTKSLYNHILLHTGRKPFTCEYCHMSFRRKDSRDHHRRKHTGEQPYQCSDCGQSFSTYNNRSKHRKKEHGEGEIECPECGEKCNSQQEIRIHLNKHLGEKLNNLQRV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00869094;
90% Identity: iTF_01245406;
80% Identity: -