Basic Information

Gene Symbol
Hivep2
Assembly
GCA_963931875.1
Location
OZ007564.1:34630059-34632005[+]

Transcription Factor Domain

TF Family
zf-GAGA
Domain
zf-GAGA domain
PFAM
PF09237
TF Group
Zinc-Coordinating Group
Description
Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 0.0071 91 5.1 0.0 27 52 2 27 1 29 0.90
2 4 3.2e-08 0.00041 22.2 0.1 21 45 30 54 24 58 0.85
3 4 0.00078 10 8.1 0.4 20 48 59 87 55 90 0.93
4 4 0.022 2.9e+02 3.5 0.1 19 43 87 111 85 119 0.82

Sequence Information

Coding Sequence
ATGTGCGATATATGTGGCaatacgtttaaaacaaaattcacttTAAAGAAACACATTGAATATCATCATTCGGAGAATCCACGTAAAGACAAAGATCCCCAGTCATGTCCCATTTGTTACAAAGTGCTGAGAGGCCACAAGGGTCTAAGGGCCCATATGAAAAATATACATGACGACAGTGAACAGGAGCACCGTTGTAAAATTTGTAATCACCTCTCGACAACAGCTAAAGGTTTGCGAGTCCACGAGATATTTCGCCACGAAAAGGAGAGAAAACACAAGTGTTCTTTGTGTTACAAAGCATTTAAGAGGCCATTGGAtttgaaaGAACATACGGCCACCCATACGGGCGAGCCTTTGTACGCTTGTGCAAATTGCGGCCAAACATTTAAGTCTAAAGCAAATATGTTTCATCATCGTAGACGTTTTCATCGACCCGAATGGACAGCTGATCGCACAAAACcaccaaaagaaaaatattcaagaaactaa
Protein Sequence
MCDICGNTFKTKFTLKKHIEYHHSENPRKDKDPQSCPICYKVLRGHKGLRAHMKNIHDDSEQEHRCKICNHLSTTAKGLRVHEIFRHEKERKHKCSLCYKAFKRPLDLKEHTATHTGEPLYACANCGQTFKSKANMFHHRRRFHRPEWTADRTKPPKEKYSRN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00742432;
90% Identity
iTF_01237182;
80% Identity
iTF_01237182;