Basic Information

Gene Symbol
-
Assembly
GCA_963931875.1
Location
OZ007560.1:70029931-70037558[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.049 8.1 8.9 0.7 1 23 1329 1352 1329 1352 0.94
2 12 1.8 3e+02 3.9 1.0 1 23 1517 1539 1517 1539 0.93
3 12 0.00069 0.11 14.7 2.8 2 23 1542 1563 1542 1563 0.97
4 12 0.00012 0.02 17.1 0.2 3 23 1571 1591 1569 1591 0.98
5 12 6.8e-06 0.0011 21.0 5.8 2 23 1598 1619 1597 1619 0.97
6 12 7.7 1.3e+03 2.0 0.1 5 23 1632 1650 1631 1650 0.96
7 12 0.033 5.5 9.4 0.1 2 23 1689 1709 1688 1709 0.96
8 12 1.1e-05 0.0018 20.4 0.4 1 19 1715 1733 1715 1737 0.95
9 12 4.6e-06 0.00076 21.5 1.8 1 23 1745 1767 1745 1767 0.99
10 12 0.00016 0.027 16.7 6.5 1 23 1773 1795 1773 1796 0.96
11 12 0.00097 0.16 14.2 6.4 1 23 1801 1823 1801 1823 0.99
12 12 0.0026 0.43 12.9 5.8 1 23 1829 1851 1829 1852 0.96

Sequence Information

Coding Sequence
ATGCAACATCATCAGAAACCCCCACCGGCCTATGGCACTGCAATTAGTCAAATACGATCTCAACATAATCAAAATAAGCATCAAcagcagcaacatcaacaacagcagcaacaacatcaTTTGCAACAACAGCAAACGGTGCAAAATAATATAAGAATTCAAATACCACCGCcgccaccaccaccaccaccaccaatTCCaattccaacaacaaaacatacATATTCGCCAAAAAATAGTGATTTGTCAATTCAAAATCATGCAACAATTTCTAGACATAGTCAGTCCCAACAACATCAGCAACAACACAAGGCATATTTGTCACAACATCAGCAAAACCCGCAGCAGCAAGAACAGCAACAATCGCAAGCAAACACGGAAAATACACACAATTCTAGCAATCACATTCCTAATTCCGAAATGTCAAACAAATCGTTATTAAAGGCAATATCCTCTTCAACATTGCAAAATCCAAATGCAAATGTTCCATCATATCCACAAGTTTCAATTAGTCCATCTGCTGCTTCAGCTTCAATGGCAGCCGTAGCGGCATCGACATTAGGAAGACATACTAACTCACCATTTGCTGCATTACTAGCAGCAGCTGCCGGCGCTCCATCGCCTTCGAATCCTTCATCTGTTTTGAGGTATGCAGAGTCACCTGTAGCTCATTATTTAGAACGGGAAAATGGTGATTTTATCGTACAAGAAACTCCGAAGCATATTGTTGAATGTGTAGAAACAGATAATGGTGAATTCTCTGTCATTGAACGTATATATCAATCTCCACCCAGTGTTTTACACATTCATGATGACGATGACGAGGATGATGATGGTGATAATTGTAAAGACCGACCTGAATTGATGGATCAAAATGAGAATAAGTCAAAACAGCATGGTGTTGCTGACGGTGAAGGTGCTAAGGTAAAATGTGAATCTGGCGAAAAgcaaagtaaaacaaaaatttactccAAAGACGATGAAACCAATAAGTGCAAAAGGAATACTAAGTCTGATGATGAAAGCTCAGTTGATAACGATATTGTTGATTTTGTTAGTATATCTAGTGACAGCGATAACGAAGAGAAAGAATTCATATCCCAAgaacgaaaaaaagaaaaaaataccaccgagaaaaacaaaaagaatcaAACAAACGTCCCATCCAGACTCTCAATGACATCAACGTCAACGTTATCGACTTTATCGTCTTCACCGCCTACTATAGCCACATTAGGTGTTGGTTACCAATCATCAACTTCTTCTTCATCCATTTCATTACATACCCCTTCTTCGGCCAACGCAAATTCAATACCAACACAACCAAATTCTACAGTCACCACCCCTACAAACAACAGCAGTGGTCGAAAGAAATCGTCTAAAAACACAATCACAGTTTTAAGCGATGTTCAGTTAAATTTAAACGAATATTTAGATTTAGTAGGAAATATAATTGCTTCGAGTAAAGTAGCGGCACAGCGTAAAACGTTTGCATCTATAGCTCCTATTCCTCTAGTGAAAATCGAAAAAGAAGAGCCCATGGATGAGTACGCAACAACAAACAATAcaacttcaaaaacaacaaccactACAGCACCAACAAACTTTGAAACACCACCAACACCTTTAAAGGCCAACAAACATGAGACTGAAGAAATAACTGATACCCATAGCAGTAGTAATAGTAGACAAACTACAACtaatcataatataattttaacaaacgAACTAGAACAGGATgaacaagaaaagaaaaaacctcAGGTCATCGAAAATACATGCGAAAACGGAACAATATATTCAGCTGTTTCCAGTGCCTCCACAAGCCTAATGACTATAAATTCCAGTCATGTTACCAGTGTTATACGTATGGCCACAACTAGTCAACAACATCAGCACCAAGCGCAACAAGAAAACCAATTGCTTAATTCTTTGGAGAGCAATAAAAACTCCTTTGAAGCTGAGGATCTATCACAAccacaacgaaaagttcaatctgtTGCAAATTCCAAATTGCTAGGCCACATGCCGTTGACACGTAAAGCTCCCAAAAAACTAGTTATAAAGCCAAAATCTTCAAAGACTGAAGTTTTGTCTACCATTACCCCTGCAAATACAGCAAACCAAATTTCCGTTAACAATGATCAGGAAATGCCTTCTACTTCGACTAAGGCTCGACAAGAATATACGAAAGATACTTCTCTTGAGGAAGATACACAAAATATCATAGatgtaaaagttaaaaatgagcCAATCACTTATGAAAATCTTCAACCACAAACTCATTATCCGCCACCTACAAATTTCAGTATCTTAGAACAACATCTTAGTTCAAAAGAACCTATTCTTGAGTTTAAAGAGGAAAAACCATGCATTACAGAAGCCAGCGTACCGCCGACGACGATTATAAAGGAGATGAAGGTAGAAAATAATGTTAACGACGATGCACGTGTTCTCTATGATTTTGCAAAttccaaaaaatcgcaaaatgaAACGCCGACGACTTTTCCATCATCCACATCGGTTTTTTCAAGTAAACAAACTAACGTAGAAATTGCACCAGTGGAAGAGCTCCAACAGCAACAACTAAACAAGAATATTAATAGTGAAAATGAAACTTCTACCTCTTCATCATCAACATATTCTTCACAATCACCTATGGGTGTTATAATGCCAACTGAAGAACATAATGAAAGTTCCACTACAAATGCTTCAGCTGCTACAAATGCCCATACCCAACATCAAACAAATGAGGTGTATACcgattttcattttaattatctCTATAGTGGCAACAATGTCACACCGGTTGCAATTGAACAAGCCGACTTAAAAAATCATCCACAATTTACATCATTTTATCCAAATTCTGGTAACAACAATACAATGCTGCTGGAGGACTCATCATCTAGTAAACACTATGCAGATtatcaacaacaacagcagcataATACACAtcaaccacaacaacaacagcagcatcAGTCTGCTGGAACATCACATCATCAATGGtttaacaataacaactacCAAACATCGGAAACCAATATTACACCAGTCACTTCAAATCTTTCAGTTTCCAATATAAATACTGCTTTATCCGTTGATGGCAGTGGGTCCACTGGTAAATATTTGGACTTAGATTCTTGTAAACgagagcaaaatattgaaataattgtTGGCGATCGTATTACTGTGCCACCGCCGCCACCGCCATCTTCCTCGACTTCGTGTTCATTTAATGGTACAACCGATAATAGTATGGCCGGTATCTGTTCGACGGCAGCCACCCTGAATATTCGAACCGATGAGAAAATGCCAGCTAAAGGTGAAATTTCCGAACAGGAAAGTAACTGCGATATTGATAACTCATGGAGTCAGCCGATGTATGGCGATATTTCGGCGCGTTTCTTTAAAACTACTTTTCCCGGCATCTTTCCTCAAGACAACGGCTGGAATCACGAGGAATATTTTACTGTACAGGATTTGAGTGCATCAACAACGGCTCAAGCCACTACTAGTGCCAATAATAGAATGAAgagttttgACCCGAGCAATAGCAgcaccaacaacaacagcaatgtACCATTGCCCATATTTTCTCAGAATTCTAATGATAATTGTAATATTGATGTAATGCCGTCAACGTCAGCAAAAATACGCAAGAGACGTAAACGTAGTTCTCAAGATGGCAAAACGTCACAATCAAATGGAAAGCGTATTCAGCCAACATCAACAGTAACCTCACAACAAATGCTTATGCAACTTCAAAGTGAGATAACAGGAGCTGAGTTTAGTTTTCAACATCAACAGCTGGAAACTCAGCAtcatttacaacaacaacatttgcaTCAACCCAGTACATCTACAGCATTTTTGGCAGGACCATCAAGTGTTAGTACTGCTTTTATgatgcaacaacagcagcaacaacaacagcaaccacAGCAACatcaaacacaacaaaaacaacgcACAAAAGTTTATGAATGCGGTCATTGTAATGCCAAATATTCCAAACTTAAAGATCGCAATGCTCACATGATTGATGTTCACAATTACATACGACAAAATAGGAGATTAGTATGCCCTACAACAGGACTTGCCACACTTCTTAACAATTCCGAAATGCAAGATGTTGCTCTACCCACAACAAGCGCTGCTGGTAACAATTTGGTGCCTGCCCTTCAGCAAAGTTCTGACTGTGTGGGCGATTTTAAACAGGGCATAGTAAAAATAGAAACTGAAAACCCAACCCAACGCGATTTATTTGGCGTAGAACCGATAAATGCCAACTTAAGTGCTAAAACGGAAATTATGGACGATGATAAAAAGAATCTAGCTCTGGTACACTTGAATGCAGTAAATTCTGAAACAAACACTGAATATGACTCTAAACTACCAACCAATAGTTTGCCATTGTCATTAACAACACCCACCAGTAAATTAACCACACTGTATCGCATGCTGGTATCGTTTAATATGACcacattaaaacaaaaccaaagtCTTTCTGAATTTGatgaaaatcttataaaatcttccatatttttttgctaCATCTGTCGGCAGAACTTCAATTCGGTAAAGCTTTACGATGCTCATTTGACCGAACATCCAGCCGAATGTTTTACATGTGGCAAAAAATTCCAACGatggaaaaatttttcattacattTAAAACGTCATTTGGGTTGGAAGGAATTCGGTTGTACGGTATGCGAAAAGAAATTTGTGGTGCGAAGTGCACTCGTTGAACATATGCGCATGCATTCCGGACTATCACCATTAAAATGTAAAGTTTGTGgAAAGCACTTTAAGCGTTACTCGAATTTGACTCAACATCGCAAGCGGCATACCAAACAATTTGTTCGTAGAAAAGAGTATGTTTGTTATTGTGGAGAAGTTTTACCATCCAAAGCACGTTTCTTATGGCACAAGGAAACTCATGATTCTAAACCAAAATGTTGTCCACATTGTTGTGATCGTTTCGTGCATGTAAACTCTTTGCGACGACACATACGTCTTGCTCATTCGGATAAATTCGATTATACTGAACCAATGGAGTGTCCTATATGCAAGCAAATATTTGCCAAAGCCTCTATGAAAGCTCACATGGCAACGCATTCCACAGAAACTCAATATGATTGTCCGATTTGCAACAAGTCCTTCTCGACAAAATGGAATCTAAAAATTCATTCTTGGGTACATGCTAATAGAACCGCTAAACCTTTTAAATGTGAACACTGCCCTAAGGCATTTGTGCGCGAAGTTGATTTCAAGAATCACATGAATTCTCACAAACAAATCAAACCGTATACGTGTGAAGTGTGCGGCTGTAAGTTTATACGAAAATACAATTACATGCGACATAGAAGAGAACATCATGGCAATAAAAAGTATACCTGTGATCTATGTAAAAAGTCGTTCCATCGCCACTACTATCTCATCGAACATAGACGCATACATACCGGCGAACGACCTTTTCAATGTTCGATATGCGGCAAAAGTTCAACAACCAAAACAAATCATAACAAACACTTAAAGATTCATCATTCACGTGATCCCTTTACAGTGGAAGTATAA
Protein Sequence
MQHHQKPPPAYGTAISQIRSQHNQNKHQQQQHQQQQQQHHLQQQQTVQNNIRIQIPPPPPPPPPPIPIPTTKHTYSPKNSDLSIQNHATISRHSQSQQHQQQHKAYLSQHQQNPQQQEQQQSQANTENTHNSSNHIPNSEMSNKSLLKAISSSTLQNPNANVPSYPQVSISPSAASASMAAVAASTLGRHTNSPFAALLAAAAGAPSPSNPSSVLRYAESPVAHYLERENGDFIVQETPKHIVECVETDNGEFSVIERIYQSPPSVLHIHDDDDEDDDGDNCKDRPELMDQNENKSKQHGVADGEGAKVKCESGEKQSKTKIYSKDDETNKCKRNTKSDDESSVDNDIVDFVSISSDSDNEEKEFISQERKKEKNTTEKNKKNQTNVPSRLSMTSTSTLSTLSSSPPTIATLGVGYQSSTSSSSISLHTPSSANANSIPTQPNSTVTTPTNNSSGRKKSSKNTITVLSDVQLNLNEYLDLVGNIIASSKVAAQRKTFASIAPIPLVKIEKEEPMDEYATTNNTTSKTTTTTAPTNFETPPTPLKANKHETEEITDTHSSSNSRQTTTNHNIILTNELEQDEQEKKKPQVIENTCENGTIYSAVSSASTSLMTINSSHVTSVIRMATTSQQHQHQAQQENQLLNSLESNKNSFEAEDLSQPQRKVQSVANSKLLGHMPLTRKAPKKLVIKPKSSKTEVLSTITPANTANQISVNNDQEMPSTSTKARQEYTKDTSLEEDTQNIIDVKVKNEPITYENLQPQTHYPPPTNFSILEQHLSSKEPILEFKEEKPCITEASVPPTTIIKEMKVENNVNDDARVLYDFANSKKSQNETPTTFPSSTSVFSSKQTNVEIAPVEELQQQQLNKNINSENETSTSSSSTYSSQSPMGVIMPTEEHNESSTTNASAATNAHTQHQTNEVYTDFHFNYLYSGNNVTPVAIEQADLKNHPQFTSFYPNSGNNNTMLLEDSSSSKHYADYQQQQQHNTHQPQQQQQHQSAGTSHHQWFNNNNYQTSETNITPVTSNLSVSNINTALSVDGSGSTGKYLDLDSCKREQNIEIIVGDRITVPPPPPPSSSTSCSFNGTTDNSMAGICSTAATLNIRTDEKMPAKGEISEQESNCDIDNSWSQPMYGDISARFFKTTFPGIFPQDNGWNHEEYFTVQDLSASTTAQATTSANNRMKSFDPSNSSTNNNSNVPLPIFSQNSNDNCNIDVMPSTSAKIRKRRKRSSQDGKTSQSNGKRIQPTSTVTSQQMLMQLQSEITGAEFSFQHQQLETQHHLQQQHLHQPSTSTAFLAGPSSVSTAFMMQQQQQQQQQPQQHQTQQKQRTKVYECGHCNAKYSKLKDRNAHMIDVHNYIRQNRRLVCPTTGLATLLNNSEMQDVALPTTSAAGNNLVPALQQSSDCVGDFKQGIVKIETENPTQRDLFGVEPINANLSAKTEIMDDDKKNLALVHLNAVNSETNTEYDSKLPTNSLPLSLTTPTSKLTTLYRMLVSFNMTTLKQNQSLSEFDENLIKSSIFFCYICRQNFNSVKLYDAHLTEHPAECFTCGKKFQRWKNFSLHLKRHLGWKEFGCTVCEKKFVVRSALVEHMRMHSGLSPLKCKVCGKHFKRYSNLTQHRKRHTKQFVRRKEYVCYCGEVLPSKARFLWHKETHDSKPKCCPHCCDRFVHVNSLRRHIRLAHSDKFDYTEPMECPICKQIFAKASMKAHMATHSTETQYDCPICNKSFSTKWNLKIHSWVHANRTAKPFKCEHCPKAFVREVDFKNHMNSHKQIKPYTCEVCGCKFIRKYNYMRHRREHHGNKKYTCDLCKKSFHRHYYLIEHRRIHTGERPFQCSICGKSSTTKTNHNKHLKIHHSRDPFTVEV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01237989;
90% Identity
iTF_01236026;
80% Identity
-