Pdom005507.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Polistes dominula
Gene Symbol
Baz2b
Assembly
GCA_001465965.1
Location
NW:3437867-3524843[+]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 3.5e-20 8.2e-17 59.7 0.0 4 76 596 668 593 669 0.93

Sequence Information

Coding Sequence
ATGGAGAAGGAGAACTCCGCATCAGGCGGAGGTGGCGGAGGTGAAGCGGCGGCAACGGCAACGTCGggctccacctccacctccgaGAAGCTCCAGGCGGACCAGGCCAATCCGCTGCTCGATCCCACTGCACTTTTTGGTGCGTACTGGCCGCGAGGAGATAGCGCAGCTTCCTCTCTTTTCGGCGGGATGCCTGGAGGCTACGGATTGGGGGCACATCATTTACCGTCGGCTTACGCCATTCTTGGCCGTGGGGGTTCAGCGCCTGGTTTTGGGGGTCATACACCGGCATccgcaccaccaccacccccgtACTCGCACAGTAGTCTCGGTACTCTCAGCGTGGCTGCCAGTCAAGCTGCGAGTCTGGgTATCACACCTGCTAGTGCGGCATGGTGGACAATGGCCTCTCATTTAGCTGCCCAGGATTACCTCGCGAGATTGCAGGGTGCAACAGGAATCCCAACTTTTCCACCTGGTGCGGAGAGTATTATACCGCCTTACCCTGCATCTCTGTTGAATCCCCCATCCCTTTCGTCCCACAAGTCTACCAAGTCTAAGTCGAGTAAAAGTCACAAGACACCGGcaagcagcagtagcagtagctcGACAACGACGAATATGACAAGCAGTAGTTTGCCGGTGTCGAGTCAGGCCACGGTAACACCAACTCATCACAGTACCTCGGCAAGCACCACGCCAAATTCGCAAACTAACGTTGTTAGcGATCCTAGTAGTATATTGGGAGGTGTGCGTTTGCCTCCTGATACGGAAATCATCAAGTATACCTCAAGTATAGTCGGTCCAAAAGTTCCTGGTACGACGAATCGTGGCAGGAAGAAGACGATCTCTTTGGATACACCGAGTGTCAGTGTTCATCCACCAACTATATCTACGTTGAGTGCTCATCAAACGAACACAACTACGTCGTCCTTGATGATGGAGCCAAGAAAGTACAATCGTACAGGGACCGAATCTAACGAGTATCGAGAGACTGTAGATCGCGTGGAGGTGATCAAATTACCGGCCCACTCAACCAACGGTTCTGTATTGTCAGCACCGTCTTCTTACACCAGTGGCAATAACTCAACCACCTCCGCCAATGACTCAGATGCTCCATTAAATTTATCCCTTAAACCTTCTTCGACGAGTAGTAGTTCGCCGATTTCCGGTAGTCAACCGCTCAGTCAGCTCAGCAATCTGAGCCAATCTTTGCTTGCCTCTGATCGGACATCGAGACGAAAACCCGGACCAAAGCCGAGAAGAGTGCCTCAAAACTCGGTACCAGTCCCAGCTTCTCCTAGTCCTTCATTGGCACAATTATTTGCTGCTGCGGATTCTCCCCAAAGGCCCAGCAGCGGTAGCGAGGAAAGTGAGAGTGCCAGTACGACTCATCATAAGGATGGTCGTCCACGAAATCTTGGTCGTGGTGTTTCCAAACCGAAGAAGAACACCGTAGCGTCGTTGCTAGCACAGAGCAGAGCATTGGGTATAAAACCCACTCCAACGTTGGATCCTAGCGCACCATTGTCACACCAGGTCTCGTTGCTGAGGTCGAACATTATTGCTGCGCAATTGCATGCCTCGGCAACGGGCCAGGTTGACGACAAGAATCAGCGATCTTTACAggagaagatgaagaataaatTGCTGGAGGCGTCGGGCGAGGAAAGCAATATGGATGTAACAAGTGAAAGCGGAAGCAACACCGACGTCCTCACCGACACAGACGAAGATAACGCTGAGGGTACGCCCAGTGCTAAGAGAAGAAAGCTTAAACCTAGCGAAAGGGATCTTCAGATGCCCTTGGAACGTGGTTGGAAACGAGAGACTGTTATTAAGGGACTAGGAAAGACTGGAGTTATTAAGGGCGATGTGTCCTATTATAGTCCTTGTGGTAAAACATTTAGGTGCAGTCCCGATCTTGTCAAGTTTTTGGAACAACAGATTCCTGCCGAGCTGACGACagcgaatttttctttttcgtcccGTCCATTGGTCGGTGAGTTTCTCCAGCCAACGTTGGGTCTGGCTGAGGCTGAATTTGTGAGGCTTGGCGCGCAAGAAGTAGCGAGACGTCTAGAAGAGATAAGAGTTGCCGGAGGGTTCAGGGACATACGAACTACGAACAATCAGTACGAGAGAGACAAGCTGGCATATGCGAAGAAACTTGCTAAGGAGGAGGCACAACGACACAAAGAGCAGGCCAGGCTCATCAAGGAACAAGAGAAGACGGAACGGCAAGAGGCAGTCAGACGGGAACGTGAAATAAGAAATCAACAGCTTCTCGAGGGTCGAAAGAGGCTCGCGTTCACGATCAAGCAGAAAATGAAGATCATCCAAGAGATCGAGCGTGGTAAGAGCAAGAGCGACGTCGCCAGAGAATTGGGCCTTGCGAGTAGCACCGTGGCAACCATTTGGAAAAATCGGGAGAGCATCGCCGAAAGTTGGAGAAATCGTGACATtatgcaacaacaacaacaacaacaacagcaacaacatcaacaacaccACTTGCCTCttcatcatcaacaacaattAGATCAGGAGGAAGCAATTCTATTGAAGAAACAAACATTCTCCTCGGTATCCCCAGTTGCTCTGAGCCTCTGCTCGGGTACGTCCTCATTGACGAACTCGAGTGTTTCGAATTTGAGCATATTACCAGTGACAACGACGGTTAACGTTGTCCCAACGACTTGCGTCGTCGGTGCATCGTCTACAAACGCGATTTCCCCAACAACGCCTCTCATGTTGACGTCAACGAACAATTCGACGACGAATATATCGACTAAtacaacgacgatgacgatgatgaacagcagcaacaacaacaataataataatactaataataataataatagtaacagtatcaacaacatcaacaacatcaATCAAGCAGCAATAATGGTAGGCGGGGCACCGACTGGTACGACAGTAGTTGCGACAACTCCTCAAGTTAATTCCCTCTTACCATCGACAACGGCACTCCAGTTGACCACCAACAACCCTGTGAACGCTGCCAACGCAGTCATCAATGCAGCATCTAACGCAgccgcagcagcagcagcagccatCGCTACTCTCACGGCTTTACCATCGACCctatcctcctcttcttcatcttcttcttcttcttctacctcctcctcctcgtctaTATGTTCCATTTCGTCCACCacgcaacaacaacaacaacaacaacaacaacaacaacaacaacaacatcaacaacatcaacaacatcaacaacaacaacaccaacaactagtactacaacaacaacaacaacaacaacaagccGTCCAACCGACGACGCCACCTACCTCGACGTCCACCGGTACCGTGACGGTCGCCGTTCAACCGGACAATACCCAGCAGGCCCAGACCCAGACGCAAAGTGGTCAGGAACTTCTGGAGGCGCGGAAAAAACGGCAGGAAGAGGTGGAGAAGATCCGACTGGAAGAGCAACAACGAAAGCAACAGGAGCGCGAATTGAAGAGACAACAGACGGTGATGTTTAAGGAACagATGTACATGCAGGAGCTCACCAAGCAGCGCGAGATGCTCTACACCGTCGAGTTGGAGcgagagagaaggagacaACATATGGCTTTGGTCAGAGCACTCGAGAATCGTCGCAAAAtggaagaaagggaaaggaaacgATTGGAAGCAAGAGCTGAGAGAATAGCaacgaaagagaaacgagCTGAACAAAGGAAAATTGAGCTTGAGTTGGTAGAACAAATTAGGAAACCCGTAGAAGACATGGAACTTACAGATCACAGAGCTCTGCCAGATATCAAGAGAATACCTGGACTGAAATTATCGGGACAGGCTTTCGCTGATATCGTCATGGTCTTCGAATTTCTTCATAATTTTGGTGAAACTTTAGGTTTTGACATGGAATCCTTACCAAGTTTAAGAAGTCTGCAATTAGCATTGTTGAACGACGAAGAAGCCGAAGAAGAAATGCTTTCTGTGATGACACATCTTTTGGTGTGCGCTATCGAGGACCCAGGTATTCCACAGCCAGCAAGACACACAACTGGCCTTGGACAAAGTTTACGACAGGCTGACATAACTCATGCCAACATAAGCGaaattttaagaatttatcttTACGCGAACGCAACAGGTGAAGTTAAAGCACTCACGGGTGTCTGTTTGGAACGTGAACGTGACAAAAGATTCGCTGATCATCATCAAAACGGTGGCGATTATGCGTCTTCTTGTTCAGGCAAAAACGCTCAATTCTTCGAGCACATGCATAAAAACGAAACGTGGAAATTGTCCGAGAGGCTCAGGGACAAACCATTCCTTGCACTTAATCCAACGCACAAAGCACAAACTTTGGCGTTCCTTTGCAATGAGCTATTGCAAAATAAAGCTGTGATTAGGCAAATCGAAGGTAGCCTGGAAACGGTAGCTcagttgaagaaagaaagatttgtATTAGATACAAAGATCAGAAAgtTGAGACAATTGCATAGTCGAAAAGTTAGAATGGAAGCAGTTGGAGTTATAGTTAACAAAACCGGTGATACGATTActatcgaaaagaaagaagttgaTGAGGAAGGAAACACAACATCGACAGCTGTTGGTACAACGCCCACTCCTGACGAGATTCATCACGAGGATGAAGTTGAGGATATGTCGGAAAACGAAAGTGAAGGAACTCAACCAGAAGAGGAGGAGGATAAAAATCTGTCGGGTGAAGAACTCGGGAAAAAATTGGATAAACTTTTGAAGCAATCCGAAGAACAATTGCAAAAATTGAATAGCTCATCGAAACAATTGCGTGCTCACACGTTCGGACAGGATAGGTATTGGAGGAGATATTGGGAATTGGCGAATGCCGGTGGTATATTTGTAGAGGCTATGGAAAGTGCGGAACCTGAGGTTTTGGAATTGCAAGCGGAATTAGATGAGAAGTACAAAAATATGCCGGTTGAGGAAAAGACCGAGACTAAACAGGAAGAACAAGCTAAGCCTAATACGGAGAATAGAGAAAACGAAGCACCGAACGAAGCCaaggatgaaaagaaattgaatgcCAACGAAGAAGATGACAATTCGAAATCTCAAAGtaaggataaaaagaacacCGATTGCGAGGAAATCAATTGCAAGAAAGAACCCGTACAGAATTGTAATTTGGATAACTCTGGTAATAacatgaaagaagaaagaagacacGATGGTGATAGTATGATGACGGATGCCAAGACCAATGTAACTTCCGAAGAAATTAAACAAGAAACGGAGGTTGTCAAAATGGAGGTAGACGTGAAGatcgaagaaacgaaaaaagaaaacgaagaaatggGAGAGGAAATGCCGAAACTTGTTGTCAAAATGATGGAAGATAAAATAGTCGAGACTATACCTAACGGCGACAAGTTTAATCACATTAACAATCTCCACAACGGCAAGGAACTCAACGGAACATTCATTTCTAtCATGTCGATAATTACAGACAACAATGCCGAGCCCAATTGGTTCTCCATTTTGCCGCGAGAAACTTGCGATACACCTGGACCTAGTACCAAGCAAATCTTTGGAATTGCTGAACCAACGGAACTCAGGATACCAGTTTTTCCACCTCCAGCTAGTCCAAATTATGACAGATGCGATAGTCCTGCCCCATTGATACTCACGCAAGATGAAGCTGCGCAACTGGAATATCTTAAAGTAAATGGATTGCCACCACCTGGGGAAGCTAAACCTGTACCGAAAGATCTAAGGTATGGTTGGTGGAGAATCACGGACGTAGACACGTTCCAAGAATTATTAGAACATTTACATTCTCGAGGAGTTCGTGAAAAAGAATTGAAGCGTACGACATGGGCTACGATGGAATCATTCTTGGCTGTAACCGGTAGGATCAACGTTGATCCAGGTAATGTCACTGCAACTGAACTTCAAGCGGAACCCGACGATCCCGACACACCGATTCCAAAACCGGATAATCCTGATGATTGGAGCGAGCAGGTAGCATTACGTGTGGATGCACAGCTTCTCGAACAGGTCGAGGCTTTGGAGGATAAGGTCGCTAACGCCAGCATGCAGGTCAAGGGCTGGAAACTTCCTCCACGGGCAGGAACCGAGGAGGCCGATGAAATCGAGAAGTTAAACGAAATGGAAAAGATCAGTGCAGTAGAACAAGCGAGACAAAGGTTACTCTCTTTGGAAGCGGCCATTGAAAGGAGATACTTGAAACCACCTTTAGGAGTTTGCACGGGAGATCCAAATCTGGCGGCGTTGAAAGCAGAACAGGCAGCCGCCGCAAACGCTAACTCGAACAATTCGGATCAGAGTAATCAGGCACCTATTCCTCAAGAAGAGACAACACCAAGAGGGCTGAACAACTGGCGAGAAGCTACCGCACGTGCACACACATCGGCTCAACTGGCTATGGCGCTTTATATGCTCGAGGCCAGCATCGCTTGGGACAAGAGCATCATGAAGGCTAATTGCCAGTTTTGTCATAGTGGAGACAACGAGGACAAGTTATTGCTTTGCGATGGCTGTGATCGCGGTTATCATACTTATTGTTTCCGTCCAAAAATGGAAAACATTCCTGATGGTGACTGgtACTGTCACGAATGTATGAACAAAGCAACAGGAGAACGTAATTGTTTGGTATGTGGGAAAAGGGTTGGGAAAAATTTGGTCCTCTGCGAGCTTTGTCCTAGGGCTTATCACACCGACTGCCATAATCCGGTTATGCCAAAAATGCCAAGAGGGAAATGGTATTGCTCTAATTGCCACAGTAAGCAaccaaagaagagaaatagtagTCGAAGGAGTCATACCAAAGGGGGAAGCAccagagagagtgagagttcTGATCATCCACCAGCTAGTCCAACGCCTTCAACGGCATCGAACACGCACGTAGAGGACGTCAGTTCGTCGGAACCGGCAACCCCTACTGCATCCCCGAGGAAGGAGGGAAACAATAGGACCCTTACTAAGAAGCAACAACGAGAGCTGGCACCTTGTAAGCTTCTTCTCGAACAGTTGGAGCAGCAGGACGAAGCCTGGCCATTCCTATTGCCGGTTAACACCAAACAGTTCCCGACCTACAAGAAAATCATTAAGACTCCCATGGATCTCAGTacgataaagaagaaactacAGGACTCTGTGTACAAGTCCCGCGATGAATTTTGCGCCGATGTCAGGCAGATGTTCATCAACTGCGAGGTATTCAACGAAGACGACAGTCCCGTAGGAAAGGCCGGACACGGGATGAGAAGTTTCTTCGAAATGCGATGGACCGAGATCACCGGTGCACCCCCACCCCATACACAGACGCATAGCTGA
Protein Sequence
MEKENSASGGGGGGEAAATATSGSTSTSEKLQADQANPLLDPTALFGAYWPRGDSAASSLFGGMPGGYGLGAHHLPSAYAILGRGGSAPGFGGHTPASAPPPPPYSHSSLGTLSVAASQAASLGITPASAAWWTMASHLAAQDYLARLQGATGIPTFPPGAESIIPPYPASLLNPPSLSSHKSTKSKSSKSHKTPASSSSSSSTTTNMTSSSLPVSSQATVTPTHHSTSASTTPNSQTNVVSDPSSILGGVRLPPDTEIIKYTSSIVGPKVPGTTNRGRKKTISLDTPSVSVHPPTISTLSAHQTNTTTSSLMMEPRKYNRTGTESNEYRETVDRVEVIKLPAHSTNGSVLSAPSSYTSGNNSTTSANDSDAPLNLSLKPSSTSSSSPISGSQPLSQLSNLSQSLLASDRTSRRKPGPKPRRVPQNSVPVPASPSPSLAQLFAAADSPQRPSSGSEESESASTTHHKDGRPRNLGRGVSKPKKNTVASLLAQSRALGIKPTPTLDPSAPLSHQVSLLRSNIIAAQLHASATGQVDDKNQRSLQEKMKNKLLEASGEESNMDVTSESGSNTDVLTDTDEDNAEGTPSAKRRKLKPSERDLQMPLERGWKRETVIKGLGKTGVIKGDVSYYSPCGKTFRCSPDLVKFLEQQIPAELTTANFSFSSRPLVGEFLQPTLGLAEAEFVRLGAQEVARRLEEIRVAGGFRDIRTTNNQYERDKLAYAKKLAKEEAQRHKEQARLIKEQEKTERQEAVRREREIRNQQLLEGRKRLAFTIKQKMKIIQEIERGKSKSDVARELGLASSTVATIWKNRESIAESWRNRDIMQQQQQQQQQQHQQHHLPLHHQQQLDQEEAILLKKQTFSSVSPVALSLCSGTSSLTNSSVSNLSILPVTTTVNVVPTTCVVGASSTNAISPTTPLMLTSTNNSTTNISTNTTTMTMMNSSNNNNNNNTNNNNNSNSINNINNINQAAIMVGGAPTGTTVVATTPQVNSLLPSTTALQLTTNNPVNAANAVINAASNAAAAAAAAIATLTALPSTLSSSSSSSSSSSTSSSSSICSISSTTQQQQQQQQQQQQQQHQQHQQHQQQQHQQLVLQQQQQQQQAVQPTTPPTSTSTGTVTVAVQPDNTQQAQTQTQSGQELLEARKKRQEEVEKIRLEEQQRKQQERELKRQQTVMFKEQMYMQELTKQREMLYTVELERERRRQHMALVRALENRRKMEERERKRLEARAERIATKEKRAEQRKIELELVEQIRKPVEDMELTDHRALPDIKRIPGLKLSGQAFADIVMVFEFLHNFGETLGFDMESLPSLRSLQLALLNDEEAEEEMLSVMTHLLVCAIEDPGIPQPARHTTGLGQSLRQADITHANISEILRIYLYANATGEVKALTGVCLERERDKRFADHHQNGGDYASSCSGKNAQFFEHMHKNETWKLSERLRDKPFLALNPTHKAQTLAFLCNELLQNKAVIRQIEGSLETVAQLKKERFVLDTKIRKLRQLHSRKVRMEAVGVIVNKTGDTITIEKKEVDEEGNTTSTAVGTTPTPDEIHHEDEVEDMSENESEGTQPEEEEDKNLSGEELGKKLDKLLKQSEEQLQKLNSSSKQLRAHTFGQDRYWRRYWELANAGGIFVEAMESAEPEVLELQAELDEKYKNMPVEEKTETKQEEQAKPNTENRENEAPNEAKDEKKLNANEEDDNSKSQSKDKKNTDCEEINCKKEPVQNCNLDNSGNNMKEERRHDGDSMMTDAKTNVTSEEIKQETEVVKMEVDVKIEETKKENEEMGEEMPKLVVKMMEDKIVETIPNGDKFNHINNLHNGKELNGTFISIMSIITDNNAEPNWFSILPRETCDTPGPSTKQIFGIAEPTELRIPVFPPPASPNYDRCDSPAPLILTQDEAAQLEYLKVNGLPPPGEAKPVPKDLRYGWWRITDVDTFQELLEHLHSRGVREKELKRTTWATMESFLAVTGRINVDPGNVTATELQAEPDDPDTPIPKPDNPDDWSEQVALRVDAQLLEQVEALEDKVANASMQVKGWKLPPRAGTEEADEIEKLNEMEKISAVEQARQRLLSLEAAIERRYLKPPLGVCTGDPNLAALKAEQAAAANANSNNSDQSNQAPIPQEETTPRGLNNWREATARAHTSAQLAMALYMLEASIAWDKSIMKANCQFCHSGDNEDKLLLCDGCDRGYHTYCFRPKMENIPDGDWYCHECMNKATGERNCLVCGKRVGKNLVLCELCPRAYHTDCHNPVMPKMPRGKWYCSNCHSKQPKKRNSSRRSHTKGGSTRESESSDHPPASPTPSTASNTHVEDVSSSEPATPTASPRKEGNNRTLTKKQQRELAPCKLLLEQLEQQDEAWPFLLPVNTKQFPTYKKIIKTPMDLSTIKKKLQDSVYKSRDEFCADVRQMFINCEVFNEDDSPVGKAGHGMRSFFEMRWTEITGAPPPHTQTHS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01234343; iTF_01232399; iTF_01235025; iTF_01233654; iTF_01089994; iTF_01454084; iTF_01539601; iTF_01255546; iTF_00966028;
90% Identity
iTF_01232399;
80% Identity
-