Pcan007815.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Polistes canadensis
Gene Symbol
egg
Assembly
GCA_001313835.1
Location
NW:196560-202422[-]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 4.4e-14 1e-10 40.2 0.0 5 70 636 695 633 701 0.85

Sequence Information

Coding Sequence
atGATGGAAGTAATTGAATTAGTTTCAGACGAAGAAGTAtccaataataaaatgaaaactcCCAAGATTTCAAAAACATGTAATactaattgtataaatttcaaatgtaattcAGGAATTGATATGAAACCTGCACCATCTTTTGCATGTGCATATTACAGTGTCaatacagaaaagaaaaaaaaacctaaagTAATATGCAAGCAATGTTTTGATATAGCTTTGGAACATCAAAAAAAATTAGTAGCAGCATTAATGGAACAAAAATCTTTATTGAAATGCGATTTTCCAGATCATACGGTTGAAGTAGAAATTTCTGACAGCGATGAATCAgacgaggaaaagaaaaaagaaattgacgACAGCGATACTTATTTACCAACGGAAGTACTTTTggatttagaagaaaaattggatATAACATTGCAATCACTTTTTAAACAATACAATGTggattatcaaataaatgaagcattaaatatattgacacAACAGTTGAAGGAAAATGATGAAAACAATACAATTATTGATGATGAGATCAAAGCCTTAACTAGTCAATTGGACACATTAAGAAATAGTTTATACGAAGACTTCAGGCCACAAATTCAAATGCTTCAGGaacttcaaataaatatagattgtgaagaaaataattatccacTTGTAGCGACTAAAAAAGTCACTCAAGTGCGTAATACACCTTGCAAATTGCAGCAAGATACTCAACCAGATATATTGCctattgaaagagaaaataaacaagTAGTTGGTTTGAATTTACCTCCTAGCGGTCCTCTTGTCAAACCGCAACCAGAACCTGACACCATAATCTACGTCATGAAACATCCTCTCATGCGATGGATTAAAGGAAAGgtattacatataatttcaaaaaatccATTACAATGTAGAGTAAGATTATTCCAAAGAAAGTATAATACAGCTATCAAGTCGGTTTTTGGCAAACAAATTGCTGTAGCAGTACCCAGTAAAGTTCTAATTCCTGTCGGTACAAGAATTGTTGCTATCTTTCACGAAGCagaaaattatgaaacaactaaagaaaaatatgattctaataatttttatagcgGTGTCATTGCAGAACCTCCTAAATCTACAAATAAGTATAGATATTTGGTGTTCTTCGACGATGGATATGTACAATACGTTACGCACAAAGATATTTTGATAGTAGCTGAAAGTTCTCCTAGAGTTTGGGAAGATGTAGCCAGTGAGTCGCgtgattttgttaaaaaatatatggaaaCGTATCCGGAAAGACCAATGGTAAAACTACAAAATGATCAGATAGTAAAAACCGAATGGAATGGTAAATGGTGGGTAGCAAGGGTTAAACAAGTAGATGCGAGTCTTGTGCAAATGCAATTTGATGCAGATCAAAGAACAGAATGGATTTATAGAGGTTCTGCTAGATTAGGACCATTATATGTTGAACTATTAAAAGCAAATGCAAGGCAGCAAGGTCATCATGCTTCTCTCAATGCATCTAGTCGTCATCGTATTCCCGTTATTTCTAATaaAAACAATCTACCTTACGTGGAATATACTTCAAATATAGAAGtagatgaggaaaaaaaaaatatcctaaTTGATAAACCATCGAACActgaatttaatgaaaatcaaaGTGTCAATACATCTAAGTCAGTCTCGACGATAGCACCATTGCAGTCTCGTGCTGTCGCTAAAAAAAGTACTAGTAAAAAAGCAGTTGTCACAGATATAACTCCTTACAACTCTACtatagaaatgaaatcttCTCATAGCATTGTTtattatcAAACACAAAATGAGATTCAAACGAGAAAATACATTCCTCATAAATGTGGACCGAAATGCATACGAAGTATATCTTTCACGCCAGAAGATTTGAAAGGTTACTCGCCCCTTTCGATTCCTTTACTATGTGGTTGGAATAGACAATTATGTAAATTTCCAAAAGCCAAAAAAGTTATACTGTATCAAGCACCGTGCGGTATAAGATTACGAAACATGGAAGAACTTCATTGTTATCTTCGTCAAACTAATAGTCCAATGTCTGtagatttatttgattttgatttttggGTCCATTGTCTGGCAGAATTTGTTTTAGATAAATgctttgttaatattaaaGATCTTAGTTATGGAATAGAAAATGTGCCAATACCGTGTGTGAATGAATTAGATCATGCTTTACCCGATACTATTAGATATAGTACTCAAAGAGAACCTACAGAAGGAGtcaatttaaatttagatCCAAATTTTCTTTGTAGTTGTGATTGCGAAGACGATTGTCAggtaataaatgataaaacaaaatgtcaATGTTGGCAATTAACAATACAGGGAGCAACTTTAGGAGGAAGAGTTCCAAATACAGCTGTTGGTTACGTTTATAAACGTTTACCAGAACCAGTAACAACTGGTATTTATGAATGTAATTCTGGTTGTAAGTGTGCCGTAAAAACTTGCTTGAATAGAGTTGTACAGCATCCactcaaattaaaattacaagttTTCAAAACGGCACCTCGAGGTTGGGGTATAAGATGCCTTACTGACATTCCATTAGGttcttttatatgtatttatgctGGACGTCTATTAACCGAACAGGGTGCAAACGAAGGTGGAAAAAACTATGGAGATGAATATCTAGCAGAGTTAGATTATGTCGAAGTTGTGGAAGGGATGAAAGAAGGTTACGAAAGCGATGTTTTTGATCCAGAAATACCTTTAACTCctgcaaaagaaaagagaaaagaacgtGGTACGAATGATgaagataataatgttaaaaataatacaaatgattCTGATGAAGATTATAACATTAGTAAATACGTGAATGTTTCTGTAGATTTAAACGAATCTTCTATCAGaaagcGCCTTAGAAAACGTAAAAGAGGTGAATCTAATTTAGATGGTTCTGAGGAAAACAGCGAAGATGGAAGTATTACAAaaagtttagaaaattttattactaaatCATCTGTGCTTGAAAATCGTTCATTGGATCAAGATACGGTAACAATAAgcgacgaagaagaaactcGAAGTAGTAGACGCGTACCAAGTAGATTCGATCCTTCGATAGAACCTTTACAATTAGATAGACCAAAGTTTAAATCTGTAAGGGATTTTTATGGAGAAGATGAAGCTGTTTACATCATGGATGCCAAAACAACAGGAAATATAGGCCGTTacttaaatcatTCCTGCGATCCAAACGTTTTCGTTCAAAACGTATTTGTAGATACACATGATGTACGTTTTCCATGGGTGGCATTTTTTGCTTTGAATTATATTCGAGCAGGCCAGGAATTAACATGGAATTATAGTTATGACGTAGGTAGCATACCGGGTAAAGTCATTATTTGTAAATGCGGTGCATCAAATTGCAGAGGTCGATTACTTTAA
Protein Sequence
MMEVIELVSDEEVSNNKMKTPKISKTCNTNCINFKCNSGIDMKPAPSFACAYYSVNTEKKKKPKVICKQCFDIALEHQKKLVAALMEQKSLLKCDFPDHTVEVEISDSDESDEEKKKEIDDSDTYLPTEVLLDLEEKLDITLQSLFKQYNVDYQINEALNILTQQLKENDENNTIIDDEIKALTSQLDTLRNSLYEDFRPQIQMLQELQINIDCEENNYPLVATKKVTQVRNTPCKLQQDTQPDILPIERENKQVVGLNLPPSGPLVKPQPEPDTIIYVMKHPLMRWIKGKVLHIISKNPLQCRVRLFQRKYNTAIKSVFGKQIAVAVPSKVLIPVGTRIVAIFHEAENYETTKEKYDSNNFYSGVIAEPPKSTNKYRYLVFFDDGYVQYVTHKDILIVAESSPRVWEDVASESRDFVKKYMETYPERPMVKLQNDQIVKTEWNGKWWVARVKQVDASLVQMQFDADQRTEWIYRGSARLGPLYVELLKANARQQGHHASLNASSRHRIPVISNKNNLPYVEYTSNIEVDEEKKNILIDKPSNTEFNENQSVNTSKSVSTIAPLQSRAVAKKSTSKKAVVTDITPYNSTIEMKSSHSIVYYQTQNEIQTRKYIPHKCGPKCIRSISFTPEDLKGYSPLSIPLLCGWNRQLCKFPKAKKVILYQAPCGIRLRNMEELHCYLRQTNSPMSVDLFDFDFWVHCLAEFVLDKCFVNIKDLSYGIENVPIPCVNELDHALPDTIRYSTQREPTEGVNLNLDPNFLCSCDCEDDCQVINDKTKCQCWQLTIQGATLGGRVPNTAVGYVYKRLPEPVTTGIYECNSGCKCAVKTCLNRVVQHPLKLKLQVFKTAPRGWGIRCLTDIPLGSFICIYAGRLLTEQGANEGGKNYGDEYLAELDYVEVVEGMKEGYESDVFDPEIPLTPAKEKRKERGTNDEDNNVKNNTNDSDEDYNISKYVNVSVDLNESSIRKRLRKRKRGESNLDGSEENSEDGSITKSLENFITKSSVLENRSLDQDTVTISDEEETRSSRRVPSRFDPSIEPLQLDRPKFKSVRDFYGEDEAVYIMDAKTTGNIGRYLNHSCDPNVFVQNVFVDTHDVRFPWVAFFALNYIRAGQELTWNYSYDVGSIPGKVIICKCGASNCRGRLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01234346; iTF_01235028; iTF_01233657; iTF_01512187; iTF_01232998; iTF_01514826; iTF_01513476; iTF_01514158; iTF_01089997; iTF_01512831;
90% Identity
iTF_01234346;
80% Identity
-