Basic Information

Insect: Pogonocherus hispidulus
Gene Symbol: topi
Assembly: GCA_963924545.1
Location: OZ004693.1:9662893-9668799[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0047 0.47 12.6 2.1 2 21 104 123 103 124 0.94

2 14 2.2e-06 0.00022 23.1 0.3 1 23 149 171 149 171 0.96

3 14 0.02 2 10.6 2.0 3 23 179 199 178 199 0.95

4 14 0.52 53 6.2 0.2 2 19 218 235 217 238 0.80

5 14 0.00092 0.093 14.8 1.1 2 23 299 320 298 320 0.97

6 14 3 3e+02 3.8 0.1 1 12 326 337 326 340 0.88

7 14 0.0051 0.52 12.5 3.4 2 22 363 383 362 386 0.88

8 14 0.038 3.9 9.7 0.1 1 23 511 534 511 534 0.97

9 14 0.0093 0.94 11.7 0.2 1 23 538 560 538 560 0.97

10 14 1.5e-06 0.00015 23.6 2.4 1 23 566 588 566 588 0.98

11 14 0.044 4.4 9.5 0.2 1 23 594 619 594 619 0.96

12 14 0.26 26 7.1 2.9 1 23 625 647 625 647 0.85

13 14 5.3e-05 0.0054 18.7 0.3 3 23 655 675 653 675 0.97

14 14 7.2e-06 0.00073 21.4 0.8 1 23 681 704 681 704 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0047	0.47	12.6	2.1	2	21	104	123	103	124	0.94
2	14	2.2e-06	0.00022	23.1	0.3	1	23	149	171	149	171	0.96
3	14	0.02	2	10.6	2.0	3	23	179	199	178	199	0.95
4	14	0.52	53	6.2	0.2	2	19	218	235	217	238	0.80
5	14	0.00092	0.093	14.8	1.1	2	23	299	320	298	320	0.97
6	14	3	3e+02	3.8	0.1	1	12	326	337	326	340	0.88
7	14	0.0051	0.52	12.5	3.4	2	22	363	383	362	386	0.88
8	14	0.038	3.9	9.7	0.1	1	23	511	534	511	534	0.97
9	14	0.0093	0.94	11.7	0.2	1	23	538	560	538	560	0.97
10	14	1.5e-06	0.00015	23.6	2.4	1	23	566	588	566	588	0.98
11	14	0.044	4.4	9.5	0.2	1	23	594	619	594	619	0.96
12	14	0.26	26	7.1	2.9	1	23	625	647	625	647	0.85
13	14	5.3e-05	0.0054	18.7	0.3	3	23	655	675	653	675	0.97
14	14	7.2e-06	0.00073	21.4	0.8	1	23	681	704	681	704	0.98

Sequence Information

Coding Sequence: ATGAGCAAtcttgataatataataataaatgtccaCAAAATCGCAGAAGATGGAATTGTAGTTACATCCATAAGGCACGAAATGGATCCGAATACCAAGGAACTCATTTCTAGGACCTTTTTTACTCCAGAAAAAGTAAGTTTTAATTGTAGAGATGACGATAAATTACATCTAAGCTATCAGAGATTTGAAGTCGAAGAGGAAGTTATAAGATGCTTAAAACTCGAAGACGTTCAAATATCCCAATCTTCAGATTCGTCTGATCTAACACTTGATAAAAAACCATTCCTTAATATCCCAACAATGATAAGATGCCAAAACTGCGAGACTAATTTTCCAACGAAATATCAATACCAACGCCATCAATGTGAATTTAACGCTGAAAGAGTTGTCTTAAAAGCAGACGCAGATGTTAAGGATGTCGACAAAGGTGTCCGTGTTAAGTACGTTTGTTCGGTTTGCGACAAGCAGTTCGTTAGTAAAAATAACTTGGAGCGTCATCAGGCCGGCCACGAAAACACCCAGGATAACATTTGTGAGCACTGTAACAAGCAATTTGTTAGCGAGAATAGGCTTCGAATTCACAAGGAAAATCATTGCAAGAAGTCTGGAGATATCTCAAAGTTCTATAGGAGCGATGTAACTGTATGGAAGTGTAGAAAATGCCACGAAGTATTTTCCTCTACGATTACTGCCAATTATCATGTAGCTATTTGTACCGAAATAATAGAATTTGATGCTGACTCGGAGAATAATAAGGAATTGAACTTCTTACAGGAAGAAATAAAAAGTTTCGCTtctttaattacaaataatgGTGATACGAGTAAAGAAAACACTTCAGGTCACGTCGACGATAAGAACATCGAGAAAATACTAACCGAGATACTACTCCAGTGTGAGTTCTGCAATAGGACTTATGCTGAAAAAAATTTGCTTTTAATGCACCAGAGAAAGCATACCACTGTGAAGAACTATGAGTGCGTTAACTGCAACCAAGTGTTCGATTCTTATGCCATTGCTGCTCAGCACTGGATGAAGAAATGCTCTGAATACGTCAGTCTCTTCTACCTGCCTAAATTAACGTATTGCGAGTATTGTGACAGGACATTTAAATCTCACGAATTACTCTAtacacacaaaataaaaaagaaacattACACTCCCAAGTTACATATCCCCAATTCATCTGATCAAGAAAAAAAGGACAGTGATAGTAAGGATAAGGCTTTGGATAACAAACAGATCCTCAATAAGTTGATCGAAGATGTCCTGAAGACTTTGGATGTCCCAgtgaataaaatcaataacgtAAACCCTCTCATTGACAATAGTAACAAGGAAAATATCAACCCAGAGAAATTAATTGATTTGAGCAAAGTGAAAACAGAGGCTCCGGAATGCGGTTCCAGCCAAATTTCCCAACCGGAGGCTCCGGAAAAGAAGAGGAGAGGCAGGAAGCGAAAATGGCCTAAGAACCAATCACTGAAGTTGAAGAAGTTTTGCGCTGAGGTTGACGATGGATTCAAGTACCAGTGTGAACGCTGCATTAAAGTTTTTGGCACTATTGTGGATCTTGAAGCGCACCGGGAAAAGGAACACGCTGCTAGCTTCACCTGTGAGGAATGTGGACAAGTTCTTCACAGTGCCAAGGCTCTACTTATTCATAGTCGTGCTCACAAGAGCTTAAAGCCATACGTTTGTGAAACATGTGGAAGAAGTTATTCCCAAACTTCTCATCTTTGGCAGCATATGCGATTCCATCAAGGTATCAAGCCTTTCGCGTGTCCTCATGAAGGTTGTGAAGCGAGATATACCATAAGACCGGATCTGAAGGACCACATCCGCAAAGTGCACACCCGAGAACGACCCTTCAGGTGTACCGTGTGCGACAAGTGCTTCCTGACGGGGTCAGTGTACTACCAACACCGATTGATACACACCAATGACAGAAGATACGGATGCGACCTTTGTCCAAAGCGGTTTTTCAGAGCAGATGCTTTAAACAATCACAGAAGGATCCACACCGATGAAAGGCCGTACCCGTGCCAAGTTTGCGGAAGAGAATTCAGGCAGAAAGGCGATAGGAATAAGCACCTGCGCACCCAGCACCCCGATGCCATCATAATGTAg
Protein Sequence: MSNLDNIIINVHKIAEDGIVVTSIRHEMDPNTKELISRTFFTPEKVSFNCRDDDKLHLSYQRFEVEEEVIRCLKLEDVQISQSSDSSDLTLDKKPFLNIPTMIRCQNCETNFPTKYQYQRHQCEFNAERVVLKADADVKDVDKGVRVKYVCSVCDKQFVSKNNLERHQAGHENTQDNICEHCNKQFVSENRLRIHKENHCKKSGDISKFYRSDVTVWKCRKCHEVFSSTITANYHVAICTEIIEFDADSENNKELNFLQEEIKSFASLITNNGDTSKENTSGHVDDKNIEKILTEILLQCEFCNRTYAEKNLLLMHQRKHTTVKNYECVNCNQVFDSYAIAAQHWMKKCSEYVSLFYLPKLTYCEYCDRTFKSHELLYTHKIKKKHYTPKLHIPNSSDQEKKDSDSKDKALDNKQILNKLIEDVLKTLDVPVNKINNVNPLIDNSNKENINPEKLIDLSKVKTEAPECGSSQISQPEAPEKKRRGRKRKWPKNQSLKLKKFCAEVDDGFKYQCERCIKVFGTIVDLEAHREKEHAASFTCEECGQVLHSAKALLIHSRAHKSLKPYVCETCGRSYSQTSHLWQHMRFHQGIKPFACPHEGCEARYTIRPDLKDHIRKVHTRERPFRCTVCDKCFLTGSVYYQHRLIHTNDRRYGCDLCPKRFFRADALNNHRRIHTDERPYPCQVCGREFRQKGDRNKHLRTQHPDAIIM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01370124;
90% Identity: iTF_01014925; iTF_00110810;
80% Identity: -