Basic Information

Insect: Anoplophora glabripennis
Gene Symbol: topi
Assembly: GCA_000390285.2
Location: NW:1248654-1254987[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0039 0.12 12.6 2.1 2 21 104 123 103 124 0.94

2 14 1.6e-06 4.8e-05 23.3 0.3 1 23 149 171 149 171 0.96

3 14 0.017 0.51 10.6 2.0 3 23 179 199 178 199 0.95

4 14 0.3 9.2 6.7 0.2 2 19 218 235 217 238 0.83

5 14 0.00077 0.024 14.8 1.1 2 23 298 319 297 319 0.97

6 14 2.8 86 3.6 0.0 1 13 325 337 325 346 0.80

7 14 0.0043 0.13 12.5 3.4 2 22 362 382 361 385 0.88

8 14 0.042 1.3 9.4 0.2 1 23 512 535 512 535 0.97

9 14 0.0078 0.24 11.7 0.2 1 23 539 561 539 561 0.97

10 14 1.3e-06 3.9e-05 23.6 2.4 1 23 567 589 567 589 0.98

11 14 0.037 1.1 9.5 0.2 1 23 595 620 595 620 0.96

12 14 0.22 6.7 7.1 2.9 1 23 626 648 626 648 0.85

13 14 4.5e-05 0.0014 18.7 0.3 3 23 656 676 654 676 0.97

14 14 6.1e-06 0.00019 21.4 0.8 1 23 682 705 682 705 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0039	0.12	12.6	2.1	2	21	104	123	103	124	0.94
2	14	1.6e-06	4.8e-05	23.3	0.3	1	23	149	171	149	171	0.96
3	14	0.017	0.51	10.6	2.0	3	23	179	199	178	199	0.95
4	14	0.3	9.2	6.7	0.2	2	19	218	235	217	238	0.83
5	14	0.00077	0.024	14.8	1.1	2	23	298	319	297	319	0.97
6	14	2.8	86	3.6	0.0	1	13	325	337	325	346	0.80
7	14	0.0043	0.13	12.5	3.4	2	22	362	382	361	385	0.88
8	14	0.042	1.3	9.4	0.2	1	23	512	535	512	535	0.97
9	14	0.0078	0.24	11.7	0.2	1	23	539	561	539	561	0.97
10	14	1.3e-06	3.9e-05	23.6	2.4	1	23	567	589	567	589	0.98
11	14	0.037	1.1	9.5	0.2	1	23	595	620	595	620	0.96
12	14	0.22	6.7	7.1	2.9	1	23	626	648	626	648	0.85
13	14	4.5e-05	0.0014	18.7	0.3	3	23	656	676	654	676	0.97
14	14	6.1e-06	0.00019	21.4	0.8	1	23	682	705	682	705	0.98

Sequence Information

Coding Sequence: ATGAGCAGTcttgataatataataataaatgtgcaCAAGATCACAGAAGATGGAATGGTAGTAACATCTATAAGGCACGAACTGGACCCGAATACCAAGGAACTCATCTCTAGAACTTATTTCACTCCGGAAAATGTAAGTTTTAACGATAATAACGACGATAAATTACACTTAAACTACCAGCGCTTCGAAGTCGACGAGGAAgttataaaatgtttgaaactgGAAGACGTCCAAATAGTTCAATCCCCAGATTCTTCAGAAGCAGCGCTTGATAAAAAGCCCGTTCTTAACATCCCAACAATGATCAGGTGCCAAAACTGTGAAACGAATTTCCCGACGAAATATCAGTACCAGCGACACCAGTGCGAATTTAATGCTGAGAGAGTTGTCCTCAAGGCCGACGCAGACGTCAAGGACATCGACAAGGGTGTTCGTGTTAAATATGTTTGCACTGTCTGCGACAAGCAGTTCGTCAGCAAGAACAATTTGGAACGCCACCAGGCCGGTCACGAGAATACCCAGGATAACATCTGTGAGCACTGTAATAAACAGTTCGTTAGTGAGAACAGGCTTAGAATCCACAAGGAAAATCATTGCAAGAAGTCTGGAGACATCTCGAAATTTTATAGAAGCGACGTAACCGTGTGGAAGTGCAGAAAATGCCACGAAGTGTTTTCCTCGACGGTTACAGCGAATTACCACGTAGCTATTTGCACTGAAATAATAGAATTTGACGCCGATTCCGAAGAGAACAAGGAACTGAGCTTCTTGCAGGAAGAAATAAAGAGTTTCGCCTCGCTGATCACGAACGGCGAGTCGAGCAAGGATAATTCCTCAGTCCACGTCGACGATAAGAACATCGAGAAGATCCTGACGGAGATCCTGCTCCAATGCGAGTTCTGTAACAGGACCTACGCTGAAAAAAACTTGCTCCTGATGCACCAACGGAAGCACACCACCGGGAAGAACTACGAATGCGTCAACTGCAACCTGGTGTTCGATTCCTACGCTGTCGCCGCTCAGCACTGGATGAAGAAATGCTCCGAATACGTGAGCCTCTTTTACCTGCCGAAGTTGACCTACTGTGAGTACTGCGACAGGACCTTCAAGTCCCACGAGCTGCTCTACACGCACAAAATCAAAAAGAAGCACTACACCCCTAAGCTGCACATCCCCAACACTTCCGATCATGAGAAAAAGGAGACCGATACCAAGGAGAAGGCTCTGGACAACAAGCAGATCCTCAACAAGTTGATCGAGGACGTGCTGAAGACTTTAGACGTGCCTGTGAACAAGATCAACAACGTCAGTCCGTCAACCATCAACGAGGACAGCAACAAGGAAAACGTCGAACCGGAGAAGTTGATCGATCTGAGTAAAGTGAAGACTGAGGTCCCGGAAGCCAGTTGCGGTGCAGTTTCCCAACAGGAAGCTCCGGAGAAGAAGAAGAGGGGCAGGAAGCGCAAATGGCCCAAGAATCAGTCGTTGAAGTTGAAGAAGTTCTGCGCGGAGGTCGACGACGGTTTCAAGTATCAGTGTGAACGGTGCATTAAGGTTTTCGGGACTATCGTCGACCTGGAAACGCATAGGGAGAAGGAACACGCCGCCAGTTTCACTTGCGAGGAGTGCGGACAGGTTCTCCACAGCGCCAAAGCGCTCCTTATCCACAGTCGCGCCCACAAGAGTTTAAAACCTTACGTTTGCGAAACCTGCGGTAGGAGTTATTCCCAAACTTCCCACCTGTGGCAGCACATGCGGTTTCACCAAGgcaTCAAGCCCTTCGCCTGCCCCCACGAAGGCTGCGAGGCGAGGTACACCATAAGGCCGGACTTGAAGGACCACATCCGCAAGGTGCACACCAGGGAACGGCCTTTCCGGTGCACAGTGTGCGACAAGTGTTTCCTGACGGGGTCGGTTTACTACCAGCACCGTTTGATACACACCAACGACAGGAGATACGGATGCGACCTTTGCCCCAAGAGATTTTTCAGGGCCGACGCCTTGAACAACCACAGGAGGATCCACACGGACGAGAGACCCTATCCCTGTCAGGTGTGCGGGAGAGAGTTTAGGCAGAAGGGAGACCGGAACAAGCACCTGCGTACCCAACATCCCGACGCTATTATACTGTAA
Protein Sequence: MSSLDNIIINVHKITEDGMVVTSIRHELDPNTKELISRTYFTPENVSFNDNNDDKLHLNYQRFEVDEEVIKCLKLEDVQIVQSPDSSEAALDKKPVLNIPTMIRCQNCETNFPTKYQYQRHQCEFNAERVVLKADADVKDIDKGVRVKYVCTVCDKQFVSKNNLERHQAGHENTQDNICEHCNKQFVSENRLRIHKENHCKKSGDISKFYRSDVTVWKCRKCHEVFSSTVTANYHVAICTEIIEFDADSEENKELSFLQEEIKSFASLITNGESSKDNSSVHVDDKNIEKILTEILLQCEFCNRTYAEKNLLLMHQRKHTTGKNYECVNCNLVFDSYAVAAQHWMKKCSEYVSLFYLPKLTYCEYCDRTFKSHELLYTHKIKKKHYTPKLHIPNTSDHEKKETDTKEKALDNKQILNKLIEDVLKTLDVPVNKINNVSPSTINEDSNKENVEPEKLIDLSKVKTEVPEASCGAVSQQEAPEKKKRGRKRKWPKNQSLKLKKFCAEVDDGFKYQCERCIKVFGTIVDLETHREKEHAASFTCEECGQVLHSAKALLIHSRAHKSLKPYVCETCGRSYSQTSHLWQHMRFHQGIKPFACPHEGCEARYTIRPDLKDHIRKVHTRERPFRCTVCDKCFLTGSVYYQHRLIHTNDRRYGCDLCPKRFFRADALNNHRRIHTDERPYPCQVCGREFRQKGDRNKHLRTQHPDAIIL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01370124;
90% Identity: iTF_01227610;
80% Identity: -