Basic Information

Gene Symbol
-
Assembly
GCA_963924545.1
Location
OZ004694.1:75222424-75227851[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.011 1.1 11.4 3.8 1 23 146 168 146 168 0.97
2 16 0.03 3 10.1 4.5 3 23 176 196 175 196 0.97
3 16 0.00039 0.04 16.0 2.6 1 23 203 225 203 225 0.96
4 16 0.0022 0.22 13.6 0.8 1 23 317 339 317 339 0.98
5 16 8.2e-07 8.3e-05 24.4 6.4 3 23 347 367 346 367 0.98
6 16 0.00086 0.087 14.9 2.9 2 23 391 413 390 413 0.96
7 16 1.1e-05 0.0012 20.8 1.6 2 23 495 516 494 516 0.96
8 16 0.0019 0.2 13.8 0.4 1 23 522 545 522 545 0.92
9 16 2.8e-06 0.00029 22.7 0.8 1 23 550 572 550 572 0.98
10 16 1.3e-05 0.0013 20.6 2.2 2 23 583 604 582 604 0.97
11 16 4.4e-07 4.5e-05 25.2 0.9 1 23 611 633 611 633 0.97
12 16 5.1e-05 0.0052 18.8 1.6 3 23 645 665 643 665 0.92
13 16 0.00017 0.017 17.1 4.4 1 23 671 693 671 693 0.99
14 16 7e-05 0.0071 18.3 1.7 1 23 699 721 699 721 0.96
15 16 1.5e-07 1.6e-05 26.7 0.4 1 23 727 749 727 749 0.99
16 16 0.00024 0.025 16.6 0.1 1 23 755 779 755 779 0.93

Sequence Information

Coding Sequence
ATGATTAACAAAGAAATAGACttaataatagataaaatatgTCGATGCTGTATGTGCGAAAATGAAAACATGCATAATGTGTTTGAAGACAAGAAAGGTGCGCAGGGCTCCACCTCGGTACTTCTTTCAGAGATGTTGATGGTTTGCACCTCTGTAGAGGTATCATTTGGGGATGGATTACCATATAGTGTATGCGACACATGTGAGAACAAGCTTTATTCAGCATACGAATTCAGGCAGCAATGCCAAAAAACAGATTCTACTCTCAGGGAGCTGACGAATACTGAATCAAAAGCTGACATAGCAAAACAAGAGGATATTGTAATACAACCTGATGTACATGATGATATGTTTGATGAAGAAGATGACTTACCATTAATACAGCGTAATGTAAAGCGCAAAAGAGGAAGACCAAAGAAAAAACAAGAAGACAATTTTGCTTGTACATTTTGTCATAAAGTGCTGCACACAAAAAAAGGTTTACGAGTACATTTACGGGCACATACTGGTGAAAAAATGAGACACTGTTTATTTTGTGATGCAAAATATACTCGTACTAATCATTTAATTCGTCACATTAGCACTCATGATAAACCTGGATTAACACATCCTTGTGAACATTGCGAAAAAACCTTTACTGCTGCGTCTGAACTATATAAACATTCTAGAGAACATGAAGAACAAGAAGGAGGTGGAGAAGATATCAAacaggaagaagaagaaattaaacctgaagtaaatttaaatacagaTAATATAAACCTCGTTGGAAACCAGATAGAGATTACTGAAGAAGCTGATGATAATAATGAcgtttttaataatgatttccCATTtagtgatgatgatgatgatgcagaaaatgatgatgatgatgattttcTTACACCCATGAAAAAGGAAAAAGCGAATAAACCTAAGAAAACTGAAGAAaaagataaaactttatatGACTGTAAAGAATGTAGCAAAGTTATGACTACATACCTAGGGTTAAAAATTCATATGCGAAGACATACTGGAGCAGATTTATCATTTTGCAaattatgcAATAAATCATTTACAAAACAGAGTCACCTAAACAGACACATGCGTACTCATGGTATAATTGAGAAGGACAAATTAAAAGCATTTAAACATGCTACAGATGTCAAAGGAAAAAGGGTTATGGAGTGTGATTTTTGTGATCGCAAGTTTAAGTATCGAAAAAGTTTTGTTCACCATATGCAAATTGAACATGGTATGTCCGATACTGAAAGTGAGTTTGTAAGTGCAGAGAGAAACATAGATAAACCCAACGAATTAAAAGACGCAATCAACAATGCAGTTCAAGAGGAaggtgCCAGTGAAGAGAATCCTGAACATAAGCTGGAAGTGAATAGTGATGGCGGTCAAGATCAACTATTGCCTAAAGATGATAATGGGGATGGCATACCTACAATGGAAAATTTAGTGGTAAAAAGAGTAAGAAACAGAAATCAAGTATGTCATGTGTGCGGTGCTAGTTTTGCCAGAGCAAACCATCTCACCAGGCATATGACGTTGCATCGGGCAGTATTGGTGCATCAATGTGATAGATGTGACAAAGCGTTTGCTGCAGAAGAATATCTTAAAAAGCATGTTGAGGAGGAGCATATTAATAAACCATATGTGTGTACAGTGTGTAATAAACCTTTTAGCAGGGGAGAACATTTGATTAGGCACTTAAAAGTGCACCAGTCCAATTCCGATAAAGAGGCAAATCTTAAGTGTTCAATATGTGATTCTACATTTACTAGGTCTGACCATTTAGCGAGACACACTAAAGTTCATTTATTACAAGATAAACGCCATGTATGCGTTGAATGTGGCAAGGCATTTAACAGACTTGACAACCTCAAGACTCATCAGAGGATTCACACTGGAGTAAAGGACACTGTCAAATTGCACCTATGCATTTACTGTGGAAAAGAATTCAATAATTCCAGTAACATGATTGTCCACATGCGTAGACACACAGGTGAGAGACCCTATAAGTGTAGCGAATGTGGAAAAGGCTTTCCGAGGTCACATGATCTGAAGTGTCACGAAAGGACACATTCTGGGGAGAAACCATACTTATGCACTCTGTGTGGAAAATCATTTAACAAGAGTAACAAATTGCTACGACATAGTCGAGTACATACAGGCGAACGACCATATGTGTGCAACATTTGTGGTCGTGCTTTTACACAGTCCAATGACTTATCTTTGCATATGAGACGCCACACAGGTGCTCGTCCATATGCCTGTGGCGTGTGCCCTGCCCGTTTCATTCAATCTGGACAACTGAAAACCCACAGGAGAACAACAGGTCACTGGATGGAAACTCAACCGGACCTTAAAGGAGGACACAGGGTGGAACCTGTCACTCCAGCTCACGAACCTATGCCGATACGATTTAAATCCCatggaaaaatgaaaaaagaaaaggaagttgTAGAAACTCTGGTTACTGACACACAAAACATTCAGCAAAACATAAGTGTTCATCCGATTGAAGAAGTAAATGTTCCAGAAGTGGCAGAAATTCAAACCCAACCACAACGAATTTTGATGGGCATCATgggtaatattaaaattcaaaatgagATGCAGCCGCTTATAATAGATAGTACAAAACTTGTCGAGCTCCACAATGCCGGACTGGTTAATTTGCCATCAGTAATTCAAACTACTAATGGCGAAGATATCAAATTAAAGTCAGAGGTTTCAAACTTTAATATCTCCCAGTGTGAACAGACCTTGGAGAAGCAGGAACCGAGTGCGAGCGGCACATTCCAAGATGCAACTGTAGTTTATTCAAGTGTCGGGCACACTTCTACCACTTTTACATCTAGCGAaaacttcaattttcaaaattaccattaa
Protein Sequence
MINKEIDLIIDKICRCCMCENENMHNVFEDKKGAQGSTSVLLSEMLMVCTSVEVSFGDGLPYSVCDTCENKLYSAYEFRQQCQKTDSTLRELTNTESKADIAKQEDIVIQPDVHDDMFDEEDDLPLIQRNVKRKRGRPKKKQEDNFACTFCHKVLHTKKGLRVHLRAHTGEKMRHCLFCDAKYTRTNHLIRHISTHDKPGLTHPCEHCEKTFTAASELYKHSREHEEQEGGGEDIKQEEEEIKPEVNLNTDNINLVGNQIEITEEADDNNDVFNNDFPFSDDDDDAENDDDDDFLTPMKKEKANKPKKTEEKDKTLYDCKECSKVMTTYLGLKIHMRRHTGADLSFCKLCNKSFTKQSHLNRHMRTHGIIEKDKLKAFKHATDVKGKRVMECDFCDRKFKYRKSFVHHMQIEHGMSDTESEFVSAERNIDKPNELKDAINNAVQEEGASEENPEHKLEVNSDGGQDQLLPKDDNGDGIPTMENLVVKRVRNRNQVCHVCGASFARANHLTRHMTLHRAVLVHQCDRCDKAFAAEEYLKKHVEEEHINKPYVCTVCNKPFSRGEHLIRHLKVHQSNSDKEANLKCSICDSTFTRSDHLARHTKVHLLQDKRHVCVECGKAFNRLDNLKTHQRIHTGVKDTVKLHLCIYCGKEFNNSSNMIVHMRRHTGERPYKCSECGKGFPRSHDLKCHERTHSGEKPYLCTLCGKSFNKSNKLLRHSRVHTGERPYVCNICGRAFTQSNDLSLHMRRHTGARPYACGVCPARFIQSGQLKTHRRTTGHWMETQPDLKGGHRVEPVTPAHEPMPIRFKSHGKMKKEKEVVETLVTDTQNIQQNISVHPIEEVNVPEVAEIQTQPQRILMGIMGNIKIQNEMQPLIIDSTKLVELHNAGLVNLPSVIQTTNGEDIKLKSEVSNFNISQCEQTLEKQEPSASGTFQDATVVYSSVGHTSTTFTSSENFNFQNYH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

90% Identity
-
80% Identity
-