Basic Information

Gene Symbol
-
Assembly
GCA_000390285.2
Location
NW:5511-15127[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.018 0.55 10.5 3.6 1 23 142 164 142 164 0.97
2 16 0.012 0.36 11.1 4.6 3 23 172 192 171 192 0.97
3 16 7.9e-05 0.0024 17.9 0.7 1 23 199 221 199 221 0.96
4 16 0.00046 0.014 15.5 1.3 1 23 311 333 311 333 0.99
5 16 6e-06 0.00018 21.4 5.2 3 23 341 361 340 361 0.98
6 16 0.00067 0.02 15.0 2.9 2 23 385 407 384 407 0.96
7 16 6.4e-05 0.002 18.2 4.0 3 23 491 511 489 511 0.96
8 16 0.0002 0.0063 16.6 0.7 1 23 517 540 517 540 0.93
9 16 2.4e-06 7.2e-05 22.7 0.8 1 23 545 567 545 567 0.98
10 16 3.9e-06 0.00012 22.0 1.8 2 23 578 599 577 599 0.97
11 16 3.7e-07 1.1e-05 25.3 0.9 1 23 606 628 606 628 0.97
12 16 4.2e-05 0.0013 18.8 1.6 3 23 640 660 638 660 0.92
13 16 9.5e-05 0.0029 17.7 4.5 1 23 666 688 666 688 0.99
14 16 5.9e-05 0.0018 18.3 1.7 1 23 694 716 694 716 0.96
15 16 1.3e-07 3.9e-06 26.7 0.4 1 23 722 744 722 744 0.99
16 16 0.0002 0.0062 16.6 0.1 1 23 750 774 750 774 0.93

Sequence Information

Coding Sequence
atgattaataaagaaatagagTTAATAATAGACAAAATTTGTAGATGTTGCATGTGCGAAAACGAAAATATGCACAATGTGTTTGAGGATAAAAAAGATTCACAGAGTCCCTCTGTACTTCTCCCAGAGATGTTGATGGCTTGTGTGTCTGTAGAGgtCGTATTTGGCGATGGATTACCTTATAATGTATGTGAGACTTGTGTGGGTAAACTAAATGCTGCATATGAATTTAGACAACAATGTCAAAAAACGGATTCTGCTCTTAGAGAGTTGATAAATACTGAATCCAAAGCTGATATAGCAAAAGAAGACATTGTCATACAACCAGATGTGCATGATGATATGTTTGACGAAGAAGATGATTTACCACTGATACAACGTAAACGCAAACGAGGGAGACCAAAGAAAAAACAAGATGATAATTACGCTTGTACATTTTGTCACAAAATATTACATACAAAGAAAGGATTACGAGTACATTTAAGAGCACATACCGGTGAAAAAATGAGACACTGCTTATTTTGTGATGCAAAATATACTCGTACAAACCATTTAATTCGTCATATTAACACACATGATAAGCCTGGTTTAACGCATCCATgtgaaaattgtgataaaaCTTTCACTGTTGCAGCTGAACTTTATAGACATTCAAGAGAACATGAAGAAGGAGAGGGAGAGGATATTAAACTAGAGGAAGATGAAATTAAACCTgaagtaaatttaaacagtGAAAATAATACAACCACCGCTGGAAACCAAATAGAAGTTATAGAAGTCGAAGACCATAATGatgtttttaataatgattttcCATTTAGTGATGATGATGATGCTAATATTGATGACGCAGATGATGACTTTCTTACAGCTATAAAGAAgggtaatgaaaataaaaccaaGAGGCAGGAAGAGAAAGACAAAACTTTATATCAATGTAAGGAATGTACAAAGGTTATGACTACGTACCTAGGATTAAAAATTCACATGAGAAGACACACCGGAGCCGATTTATCATTTTGCAAATTATGTAATAAATCGTTTACAAAATTAAGTCACCTAAATAGGCACATGCTCACTCATGGTATCATAGAAAAGGACAAGATAAAAGCATTTAAGCATAATACAGACGCCAAAGGAAAAAGGATCATGGAATGTGATTTTTGTGATCGCAAATTTAAGTATCGGAAAAGTTTCGTTCATCATATGCAGGTTGAACATGGCATGTCGGATACTGAAAGTGATTTTGCAAGTGCAGACGTGGGTGTTGACAAACCAAATCCCGAGTTAACGGACACTGTCATTAGTGCAATTCAAGAagcgGGATCCAATGAAGAAAGTCCTGAGCAAAAGCAGGAAATAAAGAATGATGTTGGGCAAGACCAAATGTTACTTGAAGAGGAAGACGCAGACGGTATCCCAGACACGGAGAACCTGCTAGTAAAAAGGGTGAGAAGTAGGAACCAAATATGCCACGTGTGTGGCGCCTGTTTTGCCCGAGCAAACCACCTCACCAGGCATATGACCTTACACCGAGCGATATTGATTCATCAATGTGACAGATGCGAAAAGGCGTTTGCCACAGAAGACTACCTTAAAAAACACGTCGAAGAAGAACATATTAATAAACCGTATGTCTGTACAGTGTGTAATAAGCCTTTTAGCAGGGGAGAGCATTTAATTAGACACCTGAAAGTGCACCAGTCCAATCCTGAAAAAGAGACAAATCTTAAGTGTTCAATATGTGATACTGAGTTTACTAGgtCTGACCATCTAGCAAGACACACTAAAGTTCATTTGCTACAGGACAAACGTCACGTATGTGTCGAATGTGGCAAGGCTTTTAATAGACTGGACAACCTAAAGACTCATCAGAGGATCCACACCGGGGTCAAGGATAACTCTAAGTTGCACCTATGCATTTATTGTGGAAAAGAATTCAATAATTCCAGTAACATGATTGTGCACATGCGGAGGCACACGGGTGAGAGACCTTACAAGTGTAATGAATGTGGGAAAGGCTTTCCAAGATCGCACGATTTGAAGTGTCACGAAAGGACGCATTCTGGAGAAAAACCATACTTGTGTACGCTGTGTGGAAAATCGttcaacaaaagtaataaactgctAAGACATAGTCGAGTACACACAGGAGAACGGCCGTACGTGTGCAACATCTGCGGTCGCGCTTTCACACAGTCAAATGACTTGTCTTTGCACATGAGGCGTCATACCGGGGCCCGACCCTATGCCTGCGGTGTGTGTCCTGCCCGTTTCATCCAGTCCGGACAACTGAAAACTCACCGTAGGACAACGGGCCACTGGATGGAAACTCAACCAGACCTGAAAGGAGGGCACAGGGTCGAACCAGTCACGCCAGCCCATGAACCTATGCCTATAAGATTTAAATCTCACGGAAAGATGAAAAAAGAGAAAGAAGTCGTGGAAACTCAGGTTACCGAAATGCAGCAGAATATAACGCTTCATCCAATCGAAGAAGTAAACGTTCCGGAAGGTCCCGACATTCAAACCCAGCCTCAGAGAATCTTGATGGGCATCATGGGTAACATTAAAATCCAGAATGAAATACAGCCACTGATAATCGATAGTACAAAACTCGTGGAGTTACATAATGCGGGGCTCGTCAATCTGCCGTCAGTAATACAAACTACCAACGGTGAAGAGATCAAATTGAAATCAGAGGTTTCCACATTCAATATCTCCCAGTGTGAAGAGAACTTGGAGAAGCACGAATCTAGCGCTAGTAACACATTCCAAGAATCAACGGTGGTTTATTCAAGTATTGGACACACTGCTACCACTTTTACGTCTAGtgaaaactttacttttcagaacTACCACTAA
Protein Sequence
MINKEIELIIDKICRCCMCENENMHNVFEDKKDSQSPSVLLPEMLMACVSVEVVFGDGLPYNVCETCVGKLNAAYEFRQQCQKTDSALRELINTESKADIAKEDIVIQPDVHDDMFDEEDDLPLIQRKRKRGRPKKKQDDNYACTFCHKILHTKKGLRVHLRAHTGEKMRHCLFCDAKYTRTNHLIRHINTHDKPGLTHPCENCDKTFTVAAELYRHSREHEEGEGEDIKLEEDEIKPEVNLNSENNTTTAGNQIEVIEVEDHNDVFNNDFPFSDDDDANIDDADDDFLTAIKKGNENKTKRQEEKDKTLYQCKECTKVMTTYLGLKIHMRRHTGADLSFCKLCNKSFTKLSHLNRHMLTHGIIEKDKIKAFKHNTDAKGKRIMECDFCDRKFKYRKSFVHHMQVEHGMSDTESDFASADVGVDKPNPELTDTVISAIQEAGSNEESPEQKQEIKNDVGQDQMLLEEEDADGIPDTENLLVKRVRSRNQICHVCGACFARANHLTRHMTLHRAILIHQCDRCEKAFATEDYLKKHVEEEHINKPYVCTVCNKPFSRGEHLIRHLKVHQSNPEKETNLKCSICDTEFTRSDHLARHTKVHLLQDKRHVCVECGKAFNRLDNLKTHQRIHTGVKDNSKLHLCIYCGKEFNNSSNMIVHMRRHTGERPYKCNECGKGFPRSHDLKCHERTHSGEKPYLCTLCGKSFNKSNKLLRHSRVHTGERPYVCNICGRAFTQSNDLSLHMRRHTGARPYACGVCPARFIQSGQLKTHRRTTGHWMETQPDLKGGHRVEPVTPAHEPMPIRFKSHGKMKKEKEVVETQVTEMQQNITLHPIEEVNVPEGPDIQTQPQRILMGIMGNIKIQNEIQPLIIDSTKLVELHNAGLVNLPSVIQTTNGEEIKLKSEVSTFNISQCEENLEKHESSASNTFQESTVVYSSIGHTATTFTSSENFTFQNYH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01227543;
90% Identity
-
80% Identity
-