Pvar002043.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Phortica variegata
Gene Symbol
-
Assembly
GCA_001014415.1
Location
JXPM01002827.1:3166-21514[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 2.5e-05 0.0021 18.4 2.1 1 23 495 517 495 517 0.97
2 18 8.3e-06 0.00069 19.9 0.4 1 23 523 545 523 545 0.97
3 18 0.00091 0.076 13.5 0.5 1 23 551 573 551 573 0.95
4 18 1.8e-05 0.0015 18.9 3.1 1 23 579 601 579 601 0.97
5 18 4e-05 0.0033 17.8 4.7 1 23 607 629 607 629 0.99
6 18 7.3e-05 0.0061 16.9 5.7 1 23 635 657 635 657 0.97
7 18 3.6e-07 3e-05 24.2 4.3 1 23 663 685 663 685 0.98
8 18 1.3e-07 1.1e-05 25.6 2.4 1 23 691 713 691 713 0.97
9 18 7.5e-05 0.0063 16.9 6.7 1 23 719 741 719 741 0.97
10 18 0.00013 0.011 16.2 6.5 1 23 747 769 747 769 0.98
11 18 1.2e-05 0.00097 19.5 4.5 1 23 775 797 775 797 0.98
12 18 8.5e-06 0.0007 19.9 8.1 1 23 803 825 803 825 0.98
13 18 6.6e-06 0.00055 20.2 7.8 1 23 831 853 831 853 0.97
14 18 7.7e-07 6.4e-05 23.2 7.7 1 23 859 881 859 881 0.98
15 18 4.3e-05 0.0036 17.7 6.9 1 23 887 910 887 910 0.97
16 18 3e-05 0.0025 18.2 0.8 1 23 916 938 916 938 0.98
17 18 0.00091 0.076 13.5 4.4 1 23 948 970 948 970 0.98
18 18 1.1e-05 0.00089 19.6 1.6 1 23 976 999 976 999 0.96

Sequence Information

Coding Sequence
ATGTCTGCCTTGCAGAATAACAACAGtcacgacgacaacaacaacagcagtaacagcaacaatgttaGTAATAACGTCATTGGCGTTGGCAATGGTTTGTTAACGCAACACGCAACAACATTgcccgctgctgctgcgggcACAACTATTACAACAAATGCTAGTGATGTAGGCAACACcaataatattgttgttgcggcgCAAGCACcgaaattaacaacaacaacacttaattTGGCGCCGCCGCTACCACTGCTGCCGACGTCGTcagcactaacaacaacagcaacaacgacactGTTAAATGTTTCTGACACGGTATCATTGTCGTcagcactaacaacaacaacatcagcagcggcaacagcaacaacattggctGAAACAGCATTAAAACCAacgaatgcaacaacagcaacaacaacaagcagaacACCATTTATAACGAATgcacaaaatTTGATTGATTGGATAATAGCGCCAAATCGACCTACAAGtgaagagcagcagcaacagcagcagcatctacaacaacaacaacaacatcagcagacTTCTACAGTCAACAACACCAGCGAAAACGTTGGCGGTGCTGACGGTGGTAATGTGCTGACACTAGAAACACAATCCATGTTAACGAATGCAGCGGGCTTAGCTGgccagcatcaacagcaacaattgcagcagcaacatcaacaattacTTGCTTCGTTGAATGCCGGCGATGACAATagacatcaacagcagcaacatgtaGCTACtgtgcagcaacagcaacaacaactacaacaccacacaataaaacaagaaGTCAACGATAATAAATCTAATCAGCAGCTAAACATGCAACACGTTAGCGCCTCCGGTGCCACGCCCTCTGTGGTAACGCCAGTTGTAACAACGGGCGGCGGCACAACGATCACATTGGGCGGGCCGCCACCGCCAGTGGCGAAAACGGAAATCAAAGATGATAGCAAACCGCCAGCACATGGCATTGAAATGTATAAAGTGAACATTGAGGATATCTCACAATTGTTCACATATCATGAAGTATTTGGTAAAATCCATGGCGATGTAGTCAATCATCCATTGGCAGCGCATAGTGGTCaattgccaccgccgccgccgttgccaCCGCAAGGACATAGTAGTGCGACAAATGCCGCTGTTGCAGCAGCGGCTGCATCAACCAATAATGCAGCTGTTGCAGCAGTAATGGCCTCAGCgaatgcagcagcagctgctgcagcGGCAGCATCGGCCGCCACCAAtgggcagcaacaacagccgccggtaacaacggcgacgacgaccGGCAGCGGTGCACAGCTAACGACGGCAACGGTAACCACAAGCGGTACGGGTACGACGACGACGGGTGAGTTGCTTATGCCGAAAATGGAGGGCGGACTGCAGGGTGTTGATGGTCAGACAACGACGGTGACATTGGCGCCGGATGGTACGCCAATAGCGACGGGCACGCATGTATGCGATATATGCGGCAAAATGTTCCAGTTTCGTTATCAACTGATTGTGCATCGGCGCTATCATAGCGAACGTAAACCGTTTATGTGTCAGGTGTGCGGACAGGGCTTTACGACATCGCAGGATTTAACGCGTCACGGCAAGATACACATTGGCGGGCCGATGTTTACGTGCATTGTGTGCTTTAATGTATTTGCGAACAATGCTAGCTTGGAACGTCATATGAAACGTCATTCGACGGATAAGCCATTTGCCTGTACGATTTGTCAGAAAACTTTTGCACGCAAAGAACATTTGGATAATCATTTTCGTTCCCATACGGGCGAGACACCGTTCCGCTGTCAATATTGCGCCAAGACATTCACACGCAAGGAGCACATGGTCAATCATGTGCGCAAACACACGGGTGAGACGCCACATCGTTGCGATATTTGTAAGAAGTCTTTCACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGGACAAACACCGCATCAGTGCGATGTCTGCGGCAAGAAATACACGCGTAAGGAGCATCTTGCAAATCATATGCGTTCGCACACCAATGATACGCCGTTCCGTTGTGAGATCTGTGGCAAGAGTTTCAGCCGAAAGGAGCACTTCACCAATCACATACTTTGGCATACAGgcGAGACACCGCATCGTTGCGATTTCTGCTCAAAGACGTTTACACGCAAGGAGCATTTGTTGAATCATGTGCGCCAGCACACCGGCGAGTCGCCGCATCGCTGCTCATACTGTATGAAGACGTTCACACGGAAGGAGCATCTGGTCAATCATATACGGCAGCACACGGGTGAGACACCGTTCAAGTGCACCTACTGCACGAAAGCGTTTACGCGCAAAGATCACATGGTTAATCATGTACGGCAACATACAGGCGAATCGCCGCACAAGTGCACTTATTGCACAAAGACGTTCACACGCAAGGAGCATCTGACGAATCATGTACGCCAGCATACCGGTGATTCACCGCATCGTTGTACATATTGCAAGAAGACGTTCACACGCAAGGAACACTTGACCAATCACGTGCGTTTGCATACGGGCGATTCACCGCACAAGTGTGAATATTGCCAGAAGACGTTCACGCGCAAAGAGCATCTCAACAATCATATGCGTCAGCATTCAAGCGATAATCCGCATACGTGCAATGTGTGCAGCAAACCGTTTACGCGTAAAGAGCATCTCATCAATCATATGTCACGTTGTCATACCGGCGATCGTCCGTTCACCTGTGAGACGTGTGGCAAATCGTTCCCGCTAAAGGGCAATCTGCTGTTCCATATGCGCAGTCACACCAAGGGTCAGGAGTGCGAGCGACCGTTCTCATGTGAGAAGTGTCCGAAGAACTTTATATGCAAAgGTCACTTGGTCTCCCATATGCGTTCGCATTCGGGTGAGAAGCCGCACGCTTGCACATTGTGCAGCAAAGCGTTTGTTGAGCGTGGCAATCTAAAGCGTCACATGAAAATGAATCATCCGGACGCAAtgatgccgccgccgccagtGCATCCCCATCCGCAGATACCTGCGGGCGTTCTGACACAAGTGAAACAAGAAGTCAAACCGATCATAAGTGAGTCGGCATACAAACACGCAAATACGTTTGCCGAAATTTGCAATTTAGCACCAATTCCCCTTTCAGTACCCCATCAAGCGGCAACAATGCATACCATACAGCAAATAACCGCCGGTGCGGGCGCTCAGGCTGTGCAATTGACGCCTGGTTTGGTGCCGTTGGTCACATCGACGCTCATTTCGCACAATAgtcaaacacaaaagcaacaacagcaacagcagcaacaacaacagcaacagcagcagcaacaacagcagcaacaacaacagcagcagcaacaacagcaacaacaacagcaacaacaacagcagcaacaacaacagcaacaagcacatcagcaacatcaacaacatgttgtacaacagcaacaagcagctgctgcagcagccGCTGCGGCTGCAgcacatcaacagcaacaacagcagcaattgcaacaacagcaacaacaattattacaaCTATCGATACAACAGGcagctcatcatcatcagcaacaacagcaggaacaacatcgtcaacatcagcatcatcaagccgcacaacaacaacagcatccaCAGGCCCCGCCACCAccccaacagcaacaacaacagccaccaCCACAAGTGCCAATCGCACTGATTAGCGATCCAAGTGCGCTTGCACGCGCAGCCATGCAATTACAGCATTTGCCTGCCAATGTTGAACAACATCCAGTGGTTTACTAA
Protein Sequence
MSALQNNNSHDDNNNSSNSNNVSNNVIGVGNGLLTQHATTLPAAAAGTTITTNASDVGNTNNIVVAAQAPKLTTTTLNLAPPLPLLPTSSALTTTATTTLLNVSDTVSLSSALTTTTSAAATATTLAETALKPTNATTATTTSRTPFITNAQNLIDWIIAPNRPTSEEQQQQQQHLQQQQQHQQTSTVNNTSENVGGADGGNVLTLETQSMLTNAAGLAGQHQQQQLQQQHQQLLASLNAGDDNRHQQQQHVATVQQQQQQLQHHTIKQEVNDNKSNQQLNMQHVSASGATPSVVTPVVTTGGGTTITLGGPPPPVAKTEIKDDSKPPAHGIEMYKVNIEDISQLFTYHEVFGKIHGDVVNHPLAAHSGQLPPPPPLPPQGHSSATNAAVAAAAASTNNAAVAAVMASANAAAAAAAAASAATNGQQQQPPVTTATTTGSGAQLTTATVTTSGTGTTTTGELLMPKMEGGLQGVDGQTTTVTLAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNASLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNDTPFRCEICGKSFSRKEHFTNHILWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCTYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHTCNVCSKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHMRSHTKGQECERPFSCEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEVKPIISESAYKHANTFAEICNLAPIPLSVPHQAATMHTIQQITAGAGAQAVQLTPGLVPLVTSTLISHNSQTQKQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAHQQHQQHVVQQQQAAAAAAAAAAAHQQQQQQQLQQQQQQLLQLSIQQAAHHHQQQQQEQHRQHQHHQAAQQQQHPQAPPPPQQQQQQPPPQVPIALISDPSALARAAMQLQHLPANVEQHPVVY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01195443;
90% Identity
iTF_01364076;
80% Identity
-