Basic Information

Gene Symbol
Aef1
Assembly
GCA_943735905.1
Location
CALSEP010001646.1:34963-35963[-]

Transcription Factor Domain

TF Family
zf-GAGA
Domain
zf-GAGA domain
PFAM
PF09237
TF Group
Zinc-Coordinating Group
Description
Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 0.0057 81 4.7 0.1 21 48 181 208 167 212 0.85
2 4 6e-05 0.85 11.0 0.0 21 46 209 234 207 236 0.91
3 4 0.00038 5.5 8.4 0.0 21 51 237 267 235 268 0.88
4 4 0.00015 2.1 9.7 0.1 21 47 265 291 261 296 0.89

Sequence Information

Coding Sequence
ATGCATATAAAAAGTTtgcaacatgcgcacgctgcagctgccatggctaattgtgaaatagtcattgttgctgcttcacccaataatgccaatgatgctaatGCAgctgctgccgccgccgctgccgccaatgcacaacagcaacaacaacaacaacaacagcaacaacaacagcagcaacagcaacaacaacaacaacagcagcaacaacaacagcaacaacaacaacaacagcagcaacaacaacagcagcagcaacaacaacaaactcatacaactgaaattcagctacctttcaacgtccatctgaccgctgccagcgctgaagctcacgccgccgctcaagctgccgccatggctgcggctcaggcagcagctcaagcagctgccgctgctgaagcccaccaacagcatccaggtcatcatcatgccatgttgcaacaacatccattggcgcatcttgtggctacggctagcactagtccggctctgtcCGAAGATCACTATGGTGGTGATCGTAATGGTCATGTGGCGGGCGGCCCGGAGAAACCCTTCCAATGCAATGTGTGCGAACGACGATTTCGTCAGCTTAGCACACTGACCAATCATGTCAAAATACACACCGGCGAGAAACCGTACAAATGCAACATTTGTGATAAAACATTTCGTCAATCGTCCACGCTAACCAATCACATGAAGATTCACACCGGTGAGAAACCGTTTACGTGCACCTTCTGTCCGAAGAACTTTCGTCAGCTGAGCACGCTGACAAATCATTTGAAAATTCATACAGGTGAAAAACCCTTCGAATGTGCCGTCTGTAAAAAACAATTCCGCCAGTCTAGCACGCTGAACAATCACATAAAGATTCATGTGATGGACAAGGTCTACTTGCCCATGAAAATAAAAACTGAGGAAGATGAGGGGTGA
Protein Sequence
MHIKSLQHAHAAAAMANCEIVIVAASPNNANDANAAAAAAAAANAQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTHTTEIQLPFNVHLTAASAEAHAAAQAAAMAAAQAAAQAAAAAEAHQQHPGHHHAMLQQHPLAHLVATASTSPALSEDHYGGDRNGHVAGGPEKPFQCNVCERRFRQLSTLTNHVKIHTGEKPYKCNICDKTFRQSSTLTNHMKIHTGEKPFTCTFCPKNFRQLSTLTNHLKIHTGEKPFECAVCKKQFRQSSTLNNHIKIHVMDKVYLPMKIKTEEDEG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00625175;
90% Identity
iTF_01181401;
80% Identity
iTF_01181401;