Basic Information

Insect: Pheosia tremula
Gene Symbol: znf423
Assembly: GCA_905333125.1
Location: HG995410.1:8269791-8278508[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 2.2 1.3e+02 3.5 0.1 1 23 84 107 84 107 0.93

2 18 5.8 3.5e+02 2.1 0.1 3 23 112 132 110 132 0.94

3 18 0.023 1.3 9.7 0.2 2 23 136 158 135 158 0.95

4 18 0.7 42 5.0 2.0 2 23 399 421 398 421 0.95

5 18 0.13 8 7.3 0.0 1 20 429 448 429 450 0.95

6 18 0.0064 0.38 11.4 0.5 2 23 460 481 459 481 0.94

7 18 6.3 3.8e+02 2.0 1.3 1 23 497 520 497 524 0.85

8 18 0.00046 0.027 15.0 1.9 1 23 529 552 529 552 0.96

9 18 3.5 2.1e+02 2.8 0.7 2 23 629 651 628 651 0.83

10 18 9.2e-06 0.00055 20.4 1.1 1 23 685 707 685 707 0.97

11 18 0.0002 0.012 16.1 1.7 1 23 714 736 714 736 0.98

12 18 8.7e-05 0.0052 17.3 2.3 1 23 741 763 741 763 0.96

13 18 0.0013 0.079 13.6 1.4 1 23 769 791 769 791 0.98

14 18 2.4e-06 0.00014 22.2 1.5 1 23 797 819 797 819 0.97

15 18 0.0006 0.036 14.7 2.5 2 23 826 847 826 847 0.97

16 18 0.00029 0.017 15.6 0.5 2 23 855 877 854 877 0.97

17 18 0.17 10 7.0 0.0 1 23 882 904 882 904 0.98

18 18 0.00021 0.013 16.1 2.5 1 23 910 933 910 933 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	2.2	1.3e+02	3.5	0.1	1	23	84	107	84	107	0.93
2	18	5.8	3.5e+02	2.1	0.1	3	23	112	132	110	132	0.94
3	18	0.023	1.3	9.7	0.2	2	23	136	158	135	158	0.95
4	18	0.7	42	5.0	2.0	2	23	399	421	398	421	0.95
5	18	0.13	8	7.3	0.0	1	20	429	448	429	450	0.95
6	18	0.0064	0.38	11.4	0.5	2	23	460	481	459	481	0.94
7	18	6.3	3.8e+02	2.0	1.3	1	23	497	520	497	524	0.85
8	18	0.00046	0.027	15.0	1.9	1	23	529	552	529	552	0.96
9	18	3.5	2.1e+02	2.8	0.7	2	23	629	651	628	651	0.83
10	18	9.2e-06	0.00055	20.4	1.1	1	23	685	707	685	707	0.97
11	18	0.0002	0.012	16.1	1.7	1	23	714	736	714	736	0.98
12	18	8.7e-05	0.0052	17.3	2.3	1	23	741	763	741	763	0.96
13	18	0.0013	0.079	13.6	1.4	1	23	769	791	769	791	0.98
14	18	2.4e-06	0.00014	22.2	1.5	1	23	797	819	797	819	0.97
15	18	0.0006	0.036	14.7	2.5	2	23	826	847	826	847	0.97
16	18	0.00029	0.017	15.6	0.5	2	23	855	877	854	877	0.97
17	18	0.17	10	7.0	0.0	1	23	882	904	882	904	0.98
18	18	0.00021	0.013	16.1	2.5	1	23	910	933	910	933	0.98

Sequence Information

Coding Sequence: ATGACTTCTGAATCATCAGATGACGAACCGCTATCTGTTTTGGTGGCTCATAAGAAGTTAAATCCTGAGAAATATGTGGACTCCAGGTTTATAGAAATTGAGGATGCCGAAGTGGCAAAGAAAAGGAAGAAGAAGTTTACCGTCGAGCAAAGCGTAACTGTAACGATAAATCTGAAAAAGCGTAAAGGAACAATAGAGCGGCCGGAGGATGTATGGCTGTACATGAAAGATTTCAACACTACAGGACCTTATAGTTGTTTACTGTGTCCTGAGTGGTTTATAAACAGATCCAAAATAATAGTACACTATATTTTAAATCATAAAAAAGATTTTTGTGGTATATGCAGGTATTTCGTGCCCAACAGAGACGCCTGGTTGGGACACCTTAAGTTTCACATGCCCTGGCCATGCTCCCAATGTGTCGAGAACTTTGAAACAGAAGGAGGACTGCGTCACCACCTCAGTAGTGCACATAAGCTAGTACACTGTCGACTTTGTCACTTCCGTGTGCCTGATGATGACCAATACAACACCCACTTGTTCCAGAAGCACAATGTCACAAATGTATCCAGCAAAGCTGAGGAGAATCTTTGGGAATTGGAATATGATGGGAGCCCAAACTTCCTTTGCTTACTATGTTCCAAATCAAATAACATGACTAAGAACTTCTTCAACCACTACATGGGTTTCCACCATTTCACATTAAAATGTTTTGCTAGTATCATTTCTGGTCGGGACTCTCCATTCTTCGTTTCTGGTGCTGATCTAAGAACTGAATTCATCGAAGGTCAGTTAAAGAATCATGCAAAAGTTGGTTACGTAGATGTAGATACAAAATCTAAATCAGAATGTGAGGGTAGTAATAAAACAGATCTTAACACTAGTGATTCGAAAGAGTTACTCAAAGTTCTAATACCAGAGATAAAGCAAGAGGATGTGAGTGGAGATGAGATGAATGATAATGAGGAGGAAGCGGAAGAGAATAAAAAGGATGAGTTAAAAGATGAAAATGATCTCACTAAGACTTATAAAGGTGATGAAGATTTTGACGTCACCCTCATGGAGTTAGTAGTAATACAGCAATGTTACTTTGATTACGTGAACAGTACACTGACTGACATAAATGCAAACATAGTACCAAAAATATCAGATATAGATTATGAGAAAGCCGTATCAGAACATCTTATGGATATAGTCTGCTCATTATGTCAAACACACCTCAACACCGTACAAAGTTTTACTAGTCACATGACAAAAATGCATGCGGTCAAGTCTCTGCCAATATTCTCGTGCAGAGTGTGTGCAACACCGTTTGACAGTCAAAATGAGTTGGACAACCACATTGCCCTGGAGTTAGGGGATTTTGAGGACTTGTGGATTTGTCAGTTTTGCGACAAGGAGTTTGATAATAGAGAGGCGACGAGACGCCACCTGACTGAGCATTTCGACACCATTGATTATGAAAACTGCTTCAGTCCACATTTAGGTTTCAAATGCAGATATTGCCCGACATTGTTCTGGAACGAAACTGACCGTGAGACACACCAAGTGCGAGCCCATTTATCTAAGCACAAAGAAGATTATTACAACTGTGATAAGTGTAATGAAATGTTCAGCGACAAGGTCTGGTTCATCCATCACTACTTAAAGGAGCACAACACAGAAGATAAGGTTCCTATATATCTTTTGAAGTGCTGCATCTGTTGTCTGGTGTTACCAAATGTCGATGATATGAGGAATCATTTCAACAGCATCCATCCAGAAGCTAAGAAAGTCTTTTGCTCTTTGGACCCATGTAAATACAAGCCTTTGAGCCATCGGAAGTCATTCAAATTGCACCTTAAGACGATCCACAGCGCGCGCCCCCGCGTGGAGCGCGCGGTGTCGTGCTCGGTGTGCGCGCGCGAGTTCAGCAGCTCGCGCGCGTGCGCCACGCACGTGTCGCAGGTGCACGGAGCCGCCAAGTTCAAGTGCAAGCTGTGCGCCGACCTGCTGCACACCAACGACGAGAGGAAACTCCACTATCTCATCTGTCACCCTGGCCAGCATCCCTTCGAGTGCCCGGAGTGCGGCAAATCTTTCCAGTACAAGTCGTCACTCTACATGCACAAGCAAGAACACCTGCCCAACAAACAGAACTACAAGTGCTCGTACTGCGGGAAATCATTTTTGAAACGCGACTCGTACCGCGAGCACGTGCAGATCCACGAGGGTCCTCGTCACGCGTGCTCGTACTGCCCGATGCGGTTCGTGCAGCGCTCCAACATGCTGCGGCACGAGCGCCGCCACACTGGCGAGCGGCCCTACGCCTGCCCGCACTGCCCCAGGAACTTCGCGGACAAGGGCGCGTGCACCGCGCATTCCAGAACGCATTCGAAGGAGGCGTCGTTTGCGTGCCTCTACTGCGGGCAGACGTTTGTGCAAAAGTCCAAACTCACTTACCACATCAGAAAACACACCGGGGAAAACCTGGAGACATGTTCGGTGTGTTCCAAGTTGTTCACGAGCGCGTGTTCGCTACGTGAACACATGAAGATACACAACGCGAACAAGCAGTCAGTCAAGTGTCCTTTATGTGACAAGAAGTACCAGGACGAGCGCTACATGCTGCGGCACCTCCGCACAGCTCACACGCGCGGCCGGTTCGAGTGCCCCGCCTGCGCCAAGCTGCTGGCCAGCCCCGCCGGCCTGCGCAACCATGTCATCACGCACGGGGCTGTTAAGGCATACAAGTGCAAACAATGCCCGAAAAGTTACTCCGTCAAGCGAACTATTGTGAAGCATTTACGCCGGCGACACGGCTTAAAGGGAACAGAAATAAACATAAAAGACTTTTACAAGAAACTAGAACCAAGGGAATGCCAATTGGGACTCGCCGACGATGTAATGGACAATATCTTTGGACCCAAGAAAAAACAAACAGGCAATGATCTGCTTTTAGCAGACTTCGTGACTCTAACCAAAGGATTGGTTAACCCGAAGAACACGCAAGAAAACGACCAGGATAATGAAAAATCCGAGTCCGAAGATGAGAAATCCAAAGAGAGTGAAAGAGACAGCGATAGTGAAGGAAATAGACCAATAAAAACTGAGACGAAAGATGATAGTGATCAGGGGGAATTGGAGCCCACGGACTTTGTAAGTGTGAAGATAGAACCAATGGATGACTACAATGAAGGTGTATAG
Protein Sequence: MTSESSDDEPLSVLVAHKKLNPEKYVDSRFIEIEDAEVAKKRKKKFTVEQSVTVTINLKKRKGTIERPEDVWLYMKDFNTTGPYSCLLCPEWFINRSKIIVHYILNHKKDFCGICRYFVPNRDAWLGHLKFHMPWPCSQCVENFETEGGLRHHLSSAHKLVHCRLCHFRVPDDDQYNTHLFQKHNVTNVSSKAEENLWELEYDGSPNFLCLLCSKSNNMTKNFFNHYMGFHHFTLKCFASIISGRDSPFFVSGADLRTEFIEGQLKNHAKVGYVDVDTKSKSECEGSNKTDLNTSDSKELLKVLIPEIKQEDVSGDEMNDNEEEAEENKKDELKDENDLTKTYKGDEDFDVTLMELVVIQQCYFDYVNSTLTDINANIVPKISDIDYEKAVSEHLMDIVCSLCQTHLNTVQSFTSHMTKMHAVKSLPIFSCRVCATPFDSQNELDNHIALELGDFEDLWICQFCDKEFDNREATRRHLTEHFDTIDYENCFSPHLGFKCRYCPTLFWNETDRETHQVRAHLSKHKEDYYNCDKCNEMFSDKVWFIHHYLKEHNTEDKVPIYLLKCCICCLVLPNVDDMRNHFNSIHPEAKKVFCSLDPCKYKPLSHRKSFKLHLKTIHSARPRVERAVSCSVCAREFSSSRACATHVSQVHGAAKFKCKLCADLLHTNDERKLHYLICHPGQHPFECPECGKSFQYKSSLYMHKQEHLPNKQNYKCSYCGKSFLKRDSYREHVQIHEGPRHACSYCPMRFVQRSNMLRHERRHTGERPYACPHCPRNFADKGACTAHSRTHSKEASFACLYCGQTFVQKSKLTYHIRKHTGENLETCSVCSKLFTSACSLREHMKIHNANKQSVKCPLCDKKYQDERYMLRHLRTAHTRGRFECPACAKLLASPAGLRNHVITHGAVKAYKCKQCPKSYSVKRTIVKHLRRRHGLKGTEINIKDFYKKLEPRECQLGLADDVMDNIFGPKKKQTGNDLLLADFVTLTKGLVNPKNTQENDQDNEKSESEDEKSKESERDSDSEGNRPIKTETKDDSDQGELEPTDFVSVKIEPMDDYNEGV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00622222;
90% Identity: iTF_01179763;
80% Identity: -