Basic Information

Insect: Pheosia gnoma
Gene Symbol: znf423
Assembly: GCA_905404115.1
Location: FR989907.1:1915570-1924196[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 2.1 1.2e+02 3.5 0.1 1 23 90 113 90 113 0.93

2 18 5.7 3.3e+02 2.1 0.1 3 23 118 138 116 138 0.94

3 18 0.022 1.3 9.7 0.2 2 23 142 164 141 164 0.95

4 18 0.69 40 5.0 2.0 2 23 405 427 404 427 0.95

5 18 0.13 7.6 7.3 0.0 1 20 435 454 435 456 0.95

6 18 0.0063 0.36 11.4 0.5 2 23 466 487 465 487 0.94

7 18 6.3 3.6e+02 2.0 1.3 1 23 503 526 503 530 0.85

8 18 0.00084 0.048 14.2 2.8 1 23 535 558 535 558 0.96

9 18 3.5 2e+02 2.8 0.7 2 23 635 657 634 657 0.83

10 18 9.1e-06 0.00052 20.4 1.1 1 23 691 713 691 713 0.97

11 18 0.0002 0.012 16.1 1.7 1 23 720 742 720 742 0.98

12 18 8.6e-05 0.0049 17.3 2.3 1 23 747 769 747 769 0.96

13 18 0.0013 0.075 13.6 1.4 1 23 775 797 775 797 0.98

14 18 2.4e-06 0.00014 22.2 1.5 1 23 803 825 803 825 0.97

15 18 0.00059 0.034 14.6 2.5 2 23 832 853 832 853 0.97

16 18 0.00029 0.017 15.6 0.5 2 23 861 883 860 883 0.97

17 18 0.029 1.7 9.3 0.1 1 23 888 910 888 910 0.97

18 18 0.00021 0.012 16.1 2.5 1 23 916 939 916 939 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	2.1	1.2e+02	3.5	0.1	1	23	90	113	90	113	0.93
2	18	5.7	3.3e+02	2.1	0.1	3	23	118	138	116	138	0.94
3	18	0.022	1.3	9.7	0.2	2	23	142	164	141	164	0.95
4	18	0.69	40	5.0	2.0	2	23	405	427	404	427	0.95
5	18	0.13	7.6	7.3	0.0	1	20	435	454	435	456	0.95
6	18	0.0063	0.36	11.4	0.5	2	23	466	487	465	487	0.94
7	18	6.3	3.6e+02	2.0	1.3	1	23	503	526	503	530	0.85
8	18	0.00084	0.048	14.2	2.8	1	23	535	558	535	558	0.96
9	18	3.5	2e+02	2.8	0.7	2	23	635	657	634	657	0.83
10	18	9.1e-06	0.00052	20.4	1.1	1	23	691	713	691	713	0.97
11	18	0.0002	0.012	16.1	1.7	1	23	720	742	720	742	0.98
12	18	8.6e-05	0.0049	17.3	2.3	1	23	747	769	747	769	0.96
13	18	0.0013	0.075	13.6	1.4	1	23	775	797	775	797	0.98
14	18	2.4e-06	0.00014	22.2	1.5	1	23	803	825	803	825	0.97
15	18	0.00059	0.034	14.6	2.5	2	23	832	853	832	853	0.97
16	18	0.00029	0.017	15.6	0.5	2	23	861	883	860	883	0.97
17	18	0.029	1.7	9.3	0.1	1	23	888	910	888	910	0.97
18	18	0.00021	0.012	16.1	2.5	1	23	916	939	916	939	0.98

Sequence Information

Coding Sequence: ATGACTTCTGAATCATCAGATGACGAACCGCTATCTGTTTTGGTGGCACATAAGAAGTTAAACCCAGAGAAATATGTGGACTCCAGGTTTATAGAAATTGAGGATGCGGAGGTAGCAAAGAAAAGGAAGAAAAAGTTTGCCGTCGAAGAAAGCGTAACTGTTACGATAAATCTGAAAAAGCGTAAAGGAATTGGACGGTCACCGCCAACAATAGAGCGGCCGGAGGATGTATGGCTGTACATGAAAGATTTCAACAATACAGGACCTTATAGTTGTTTACTGTGTCCGGAGTGGTTTATAAACAGATCCAAAATAATAGTACACTATATTTTAAATCATAAAAAAGATTTTTGTGGTATATGCAGGTATTTCGTGCCCAACAGAGACGCCTGGTTGGGACACCTTAAGTTTCACATGCCCTGGCCATGCTCCCAGTGTGTTGAGAACTTTGAAACAGAAGGAGGACTGCGTCACCACCTTAGTAGTGCACATAAGCTAGTACACTGTCGTCTTTGCCACTTCCGTGTGTCTGATGATGACCAATACAACACCCACTTGTTCCAGAAGCACAATGTCACAAATGTATCCAGCAAAGGTGAGGAGAATCTTTGGGAATTGGAATATGATGGGAGCCCAAACTTCCTTTGCTTACTATGTTCTAAGTCAAATAACATGACTAAGAACTTCTTCAACCACTACATGGGTTTCCACCATTTCACATTGAAATGTTTTGCCAGTACCATTTCTGGTCGGGACTCTCCATTCTTCGTTTCTGGTGCTGATCTAAGAACTGAATTCATCGAAGGTCAGTTAAAGAATCATGCGAAAGTTGGTTATGTAGATGTAGATACAAAATCTAAATCAGTATGTGAGGGTAGTAACAAAACAGATCTTAGCACCGGTGATTCGAAAGAGTTACTCAAAGTTCTAATACCAGAGATAAAGCAAGAGGATGTGAGTGGAGATGAGATGAATGATAATGAGGAGGAAGCAGAGGAGAATAAAAAGGATGAGTCAAAAGATGAAAATGATCTCACTAAGACTTATAAAGGTGATGAAGATTTTGACGTCACCCTCATGGAGCTAGTAGTAATACAGCAATGTTACTTTGATCATGTGAACAGTACACTGACTGACATATATGCAAACATAGTACCAAAAATATCAGACATAGATTATGAGAAAGCCGTATCAGAACATCTTATGGACATAGTCTGTTCGTTATGCCAAACACACCTCAACACAGTACAAAGTTTTACTAGTCACATGACAAAAATGCACGCGGTCAAGTCTCTGCCAATATTCTCGTGCAGAGTGTGTGCAACACCGTTTGACAGTCAAAATGAGTTGGACAACCACATTGCCCTGGAGTTAAGGGATTTTGAGGACTTGTGGATCTGTCAGTTTTGTGATAAGGAGTTTGATAATAGAGAGGCGACGCGACGCCACCTGACTGAGCATTTCGACACCATTGATTATGAAAACTGCTTCAGTCCACATTTAGGATTCAAATGCAGATATTGCCCGACTTTGTTCTGGAACGAAACTGACCGTGAGACACACCAAGTTCGGGCTCACTTATCTAAGCACAAAGAAGATTATTACAACTGTGATAAGTGTAATGAAATGTTTAGTGACAAGGTCTGGTTCATCCATCACTACTTAAAGAAGCACAACACAGAAGATAAGGTTCCTATATATCTTTTGAAGTGCTGCATCTGTTGTCTGGTGTTACCAAATGTCGATGATATGAGGAATCATTTTAACAGCATCCATCCAGAAGCCAAGAAAGTCTTTTGCTCTTTGGACCCATGTAAATATAAACCTTTGAGCCATCGGAAGTCATTCAAATTGCACCTTAAGACGATCCACAGCGCGCGCCCCCGCGTGGAGCGCGCGGTGTCGTGCTCGGTGTGCGCGCGCGAGTTCAGCAGCTCGCGCGCGTGCGCCACGCACGTGTCGCAAGTGCACGGAGCCGCCAAGTTCAAGTGCAAGCTGTGCGCCGACCTGCTGCACACCAACGACGAGAGGAAACTCCACTATCTCATCTGTCACCCTGGCCAGCATCCCTTCGAGTGCCCGGAGTGCGGCAAGTCGTTTCAGTACAAGTCGTCGCTTTACATGCACAAGCAAGAACACCTGCCGAACAAACAGAACTACAAGTGCTCGTACTGCGGGAAATCATTTTTGAAACGCGACTCGTACCGCGAGCACGTCCAGATCCACGAGGGCCCGCGCCACGCGTGCTCGTACTGCCCGATGCGGTTCGTGCAGCGCTCCAACATGCTGCGGCACGAGCGCCGCCACACCGGCGAGCGGCCCTACGCCTGCCCGCACTGCCCCAGGAACTTCGCGGACAAGGGCGCGTGCACCGCGCATTCCAGAACGCATTCGAAGGAGGCGTCGTTTGCCTGCCTCTACTGCGGGCAGACGTTTGTGCAAAAGTCCAAACTCACTTACCACATCAGAAAACACACCGGGGAAAACCTGGAGACATGTTCGGTGTGTTCCAAGTTGTTCACGAGCGCGTGTTCGCTACGTGAACACATGAAGATACACAACGCTAACAAGCAGTCGGTCAAGTGTCCTTTATGCGACAAGAAGTACCAGGACGAGCGCTACATGCTGCGGCACCTGCGCACAGCGCACACGCGCGGTCGGTTCTGCTGCCCCGTGTGCGCCAAGCTGCTGGCCAGCCCCGCCGGCCTGCGCAACCACGTCATCACGCACGGGGCTGTTAAGGCATACAAGTGCAAGCAATGCCCGAAAAGTTACTCCGTCAAGCGAACTATTGTGAAACATTTACGCCGGCGACACGGCTTAAAGGGAACAGAAATAAACATAAAAGACTTTTACAAAAAACTAGAACCGAGGGAATGCCAATTGGGACTCGCCGAAGATGTAATGGACAATATCTTTGGACCCAAGAAAAAACAAGCAGTCAATGATCTGCTTATAGCGGACTTCGTAACTCTAACCAAAGGATTGGTAAAGCCGAAGGACACGCAAGAAAATGACCAGGATAATGAAAAATCCGAGTCCGAAGATGAGAAATCCAAAGAGAGTGAAAGAGACAGCGATGGTGAAGGAAATAGACCAATAAAAACTGAGACGAAAGATGACAGTGATCAGGGGGAATTGGAGCCTACGGACTTTGTAAGCGTGAAGATAGAGCCAATGGATGACTACAATGAAGGTGTATAG
Protein Sequence: MTSESSDDEPLSVLVAHKKLNPEKYVDSRFIEIEDAEVAKKRKKKFAVEESVTVTINLKKRKGIGRSPPTIERPEDVWLYMKDFNNTGPYSCLLCPEWFINRSKIIVHYILNHKKDFCGICRYFVPNRDAWLGHLKFHMPWPCSQCVENFETEGGLRHHLSSAHKLVHCRLCHFRVSDDDQYNTHLFQKHNVTNVSSKGEENLWELEYDGSPNFLCLLCSKSNNMTKNFFNHYMGFHHFTLKCFASTISGRDSPFFVSGADLRTEFIEGQLKNHAKVGYVDVDTKSKSVCEGSNKTDLSTGDSKELLKVLIPEIKQEDVSGDEMNDNEEEAEENKKDESKDENDLTKTYKGDEDFDVTLMELVVIQQCYFDHVNSTLTDIYANIVPKISDIDYEKAVSEHLMDIVCSLCQTHLNTVQSFTSHMTKMHAVKSLPIFSCRVCATPFDSQNELDNHIALELRDFEDLWICQFCDKEFDNREATRRHLTEHFDTIDYENCFSPHLGFKCRYCPTLFWNETDRETHQVRAHLSKHKEDYYNCDKCNEMFSDKVWFIHHYLKKHNTEDKVPIYLLKCCICCLVLPNVDDMRNHFNSIHPEAKKVFCSLDPCKYKPLSHRKSFKLHLKTIHSARPRVERAVSCSVCAREFSSSRACATHVSQVHGAAKFKCKLCADLLHTNDERKLHYLICHPGQHPFECPECGKSFQYKSSLYMHKQEHLPNKQNYKCSYCGKSFLKRDSYREHVQIHEGPRHACSYCPMRFVQRSNMLRHERRHTGERPYACPHCPRNFADKGACTAHSRTHSKEASFACLYCGQTFVQKSKLTYHIRKHTGENLETCSVCSKLFTSACSLREHMKIHNANKQSVKCPLCDKKYQDERYMLRHLRTAHTRGRFCCPVCAKLLASPAGLRNHVITHGAVKAYKCKQCPKSYSVKRTIVKHLRRRHGLKGTEINIKDFYKKLEPRECQLGLAEDVMDNIFGPKKKQAVNDLLIADFVTLTKGLVKPKDTQENDQDNEKSESEDEKSKESERDSDGEGNRPIKTETKDDSDQGELEPTDFVSVKIEPMDDYNEGV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00622222;
90% Identity: iTF_01180579;
80% Identity: -