Pgno016299.1
Basic Information
- Insect
- Pheosia gnoma
- Gene Symbol
- ZFX
- Assembly
- GCA_905404115.1
- Location
- FR989912.1:402289-405091[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 19 0.11 6.5 7.5 3.4 1 23 27 49 27 49 0.94 2 19 0.00012 0.0071 16.8 2.2 2 23 56 78 55 78 0.92 3 19 2.5e-06 0.00014 22.1 0.9 1 23 84 106 84 106 0.99 4 19 2.5e-06 0.00015 22.1 4.3 1 23 112 134 112 134 0.98 5 19 8.1e-05 0.0046 17.4 0.3 1 23 140 162 140 162 0.98 6 19 3.4e-06 0.0002 21.7 2.6 1 23 168 190 168 190 0.97 7 19 0.00042 0.024 15.1 5.2 1 23 196 219 196 219 0.96 8 19 0.027 1.6 9.4 1.3 2 23 282 302 282 302 0.97 9 19 6.1e-06 0.00035 20.9 1.0 1 23 307 330 307 330 0.96 10 19 6.8e-08 3.9e-06 27.0 1.9 1 23 336 358 336 358 0.98 11 19 2.2e-05 0.0012 19.2 0.3 1 23 364 386 364 386 0.98 12 19 0.00014 0.0078 16.7 0.1 2 23 392 413 391 413 0.96 13 19 0.5 29 5.4 2.2 1 23 493 514 493 514 0.94 14 19 0.0014 0.083 13.4 0.5 2 23 630 652 630 652 0.96 15 19 4.6e-05 0.0026 18.2 0.1 1 23 658 680 658 680 0.96 16 19 9.4e-06 0.00054 20.3 2.1 1 23 686 708 686 708 0.98 17 19 0.00086 0.05 14.1 6.6 2 23 715 736 714 736 0.97 18 19 0.00014 0.0083 16.6 3.1 1 23 742 764 742 764 0.98 19 19 9.3e-05 0.0053 17.2 3.2 1 23 769 792 769 792 0.97
Sequence Information
- Coding Sequence
- ATGAGGAAAGGGCGAATGGATGATGAGACTAGACAGGAGTTAAGCGAGGTCCAAACAAAGGTTAATGGAAAAGTCTACTACACTTGTAAGATATGTGGAAAGAATTTGAGCTCGACGCACACATACGTGTTCCATAAGCGCATACACACAGGGGAGCGGCCGTGCGTGTGTCACATATGTGGCAAACAATTCCGGGTAGCCAACGGCCTTCAGCGACATTTGACCGAGACCCATGAACGAATAAAGCGTTACACTTGCATGTTGTGTCCGAAAACCTTCGCGAATACACAGAACTTGAAGCAGCACTTGCGAATTCACACCGGCGAGCGACCTTTCGTTTGTACACACTGCGGCAAGCGGTTCCGGCAGCGCGGGTCTCTGCATGTGCATCTGAAGGTTCACACGGAGCAGTTCCCTTACCAGTGCGCAGATTGTGGGGAGAAGTTCAGATTGCGCGCTGGTTTAGTCCGACATAAACTGAAGCATACTGGTGAAAGGCCCCACGTTTGTCTACTCTGCGGAAAGACGTTCAGACAGAAATATGAGCTGAACAACCATAGACTAATGCATTCTGATAGCAAGCCGTTCGCGTGTTGTATCTGTGGAGCGACATTCAAGCAACGCAGGACTCTGAGGCACCATACTAAGAGGGTGCATGAAAATGATGCGAGTCGTGAGGTGACGCAGCCGCTAGTGTACCACCCTGGTCCACTGTATATAGAGAAGCATGAAATCAAAATCGAAGTGGACGAAGACACCGATACCTCAAACTTTGTTAAAATCATCGAACATATTGAAAAACCTACTATAATCACTGTAGGTGAGGATGGGAAGAGATACGGGACCTGTAAAGTGTGTAATAAGACTGTTAGGTTAACATCTTGGAGACGACACGCGCGGAGCCATCAGGGGAACCGATACAGCTGCCACACCTGCGGGCTGGGCTTCAACGACAACGGAAACCTGTCTAGACACAGAAGAGCGTTGCACGCGAAACAACGCCCCTATTCCTGTCCCGTATGCAACAAAAGCTTCTCTAGAAACAGCCATTTGGAAGACCACGTGAAATCTCATTCGGAGAGCAGAGAATTCGTTTGTGATTTGTGCGGTAAAGCTTCGAAGTCGAGTGCGGCGTTGAGGATGCATCGGAAGACGCACGACGCGCGCCGGCTGCAGTGCATGGAGTGCGGGGCGCAGTTCAAGAGGCGGGCGGAGTTGAGAGCCCACGTGACGGTGCATACTGGGGAGAAGGCGCATTTGTGCGGCTGCGGCCGGGCGTTCAGACTTAGGATTGACGGCTCGCTTTCTTGCAGATTCGAGGACATAGCCAACATAGTGGTCACCCTGGCCCCGCCGCAGTACGCCGCGGCAGCCGGCAGCCCCGCGCAGCGCACGCGGGACTGCCAGTTCTGCGACGCACAGCACGCCGACACCTCCTACAAGGAGCACTTGGTCACAGCGCACGCCGACATGCTGTTCCACTGCGAGGAGTGCGACAAGTACATCGACAGAAAAGACTTCATGCTGCACATGTCGCTACACGCTGTACAATATTCTACAGACGGCGATAGAACTGACATAAAGAGGTGTAGGAAAGTTAAAAAGAAGACACAAGATGAGAACACTGACAGCGTCAGCGATGGAGACAAAACTCTTCCACAAAAACCAGAAGACCGTCCGGAGAACGAGTTCTCGGACCACAGTGACACCGAGTACGGTTTTGGACCACTACCCGAATCCGTTTTCGAAGCGATAGAAGACTCCCAGGACAGTCAGCCGCCCGATGAGGACCCTGTCCATAATGAAACTGAAAACTGTGACACTAATAGTCCACCGCTAGTGGAGAATACAGAAAAAGTTGTAATTAAAAGTCACAAGAAGACCAGAACGTGTCCAATTTGTTCCAAAGTCTACACAGCGTCGTCTAGCTACTTCTATCATCTGAAGTACTCTCACAATACAAACAAAGACTATGAATGTGATGTGTGCGGTAGAAAATTCGGGACCAAAGCTAGTTTGGCGCAGCACGCGCTGCTGCATACAGGGCAGTGTCAGTTCGAGTGCAAAGAGTGCAAGAAACGGTTTCGATCAAAAGCGAGCCTCTACATCCATGAGCAGACCCACAATGGTATAAAAACATGGTCCTGTAATCAATGTCACAAGTCCTTCAGATGGCGGACACATTTACTGAGACATATGAAGCGGCATTCGGCTGAAAAGGTTCACGTTTGTTCGGTCTGCGGCCGCGGGTTCAGCATCAGGTGCGACCTGTTAAGACACACGCGAACGCATAACGCGGGCACCTTCACGTGCGAGAAGTGCGGACACAAGTTCGCTCAGCTGAGGTATCTCAAAGTGCACATGGACAAGAAACATTTGGAGGCGGAGAAGGAATCTCATTGCGTGTAA
- Protein Sequence
- MRKGRMDDETRQELSEVQTKVNGKVYYTCKICGKNLSSTHTYVFHKRIHTGERPCVCHICGKQFRVANGLQRHLTETHERIKRYTCMLCPKTFANTQNLKQHLRIHTGERPFVCTHCGKRFRQRGSLHVHLKVHTEQFPYQCADCGEKFRLRAGLVRHKLKHTGERPHVCLLCGKTFRQKYELNNHRLMHSDSKPFACCICGATFKQRRTLRHHTKRVHENDASREVTQPLVYHPGPLYIEKHEIKIEVDEDTDTSNFVKIIEHIEKPTIITVGEDGKRYGTCKVCNKTVRLTSWRRHARSHQGNRYSCHTCGLGFNDNGNLSRHRRALHAKQRPYSCPVCNKSFSRNSHLEDHVKSHSESREFVCDLCGKASKSSAALRMHRKTHDARRLQCMECGAQFKRRAELRAHVTVHTGEKAHLCGCGRAFRLRIDGSLSCRFEDIANIVVTLAPPQYAAAAGSPAQRTRDCQFCDAQHADTSYKEHLVTAHADMLFHCEECDKYIDRKDFMLHMSLHAVQYSTDGDRTDIKRCRKVKKKTQDENTDSVSDGDKTLPQKPEDRPENEFSDHSDTEYGFGPLPESVFEAIEDSQDSQPPDEDPVHNETENCDTNSPPLVENTEKVVIKSHKKTRTCPICSKVYTASSSYFYHLKYSHNTNKDYECDVCGRKFGTKASLAQHALLHTGQCQFECKECKKRFRSKASLYIHEQTHNGIKTWSCNQCHKSFRWRTHLLRHMKRHSAEKVHVCSVCGRGFSIRCDLLRHTRTHNAGTFTCEKCGHKFAQLRYLKVHMDKKHLEAEKESHCV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01073788;
- 90% Identity
- iTF_01180486;
- 80% Identity
- -