Ndro007601.1
Basic Information
- Insect
- Notodonta dromedarius
- Gene Symbol
- zfh1
- Assembly
- GCA_905147325.1
- Location
- LR990177.1:10469309-10472146[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 19 0.11 7.2 7.5 3.4 1 23 27 49 27 49 0.94 2 19 0.00035 0.023 15.3 1.4 2 20 56 74 55 76 0.93 3 19 0.019 1.3 9.8 0.2 7 23 90 106 90 106 0.95 4 19 4.5e-06 0.0003 21.3 4.1 1 23 112 134 112 134 0.98 5 19 3.9e-05 0.0027 18.3 0.3 1 23 140 162 140 162 0.98 6 19 5.9e-06 0.0004 20.9 2.0 1 23 168 190 168 190 0.95 7 19 0.00039 0.026 15.2 5.2 1 23 196 219 196 219 0.96 8 19 0.66 45 5.0 2.6 2 23 277 297 277 297 0.96 9 19 4e-06 0.00027 21.4 0.6 1 23 303 326 303 326 0.96 10 19 6.7e-08 4.5e-06 27.0 1.9 1 23 332 354 332 354 0.98 11 19 8.7e-05 0.0059 17.2 0.5 1 23 360 382 360 382 0.98 12 19 1.2e-05 0.00079 20.0 0.2 1 23 387 409 387 409 0.97 13 19 0.37 25 5.8 1.7 1 23 468 489 468 489 0.94 14 19 0.0014 0.098 13.4 0.6 2 23 606 628 606 628 0.96 15 19 0.00013 0.0088 16.7 0.5 1 23 634 656 634 656 0.95 16 19 6.1e-06 0.00042 20.8 1.9 1 23 662 684 662 684 0.98 17 19 0.0076 0.52 11.1 6.1 2 23 691 712 690 712 0.96 18 19 0.00025 0.017 15.8 3.7 1 23 718 740 718 740 0.98 19 19 0.00064 0.044 14.5 3.2 1 23 745 768 745 768 0.96
Sequence Information
- Coding Sequence
- ATGAGGAAAGGGCGGATGGACGATGAAACTAGACGAGAGTTGAGCGAAGTCCAAACCAGAATTAACGGGAAAGTGTACTACACGTGTAAGATATGCGGAAAGAATTTGAGTTCAACGCACACCTACGTGTTCCACAAGCGCATCCACACGGGGGAGCGGCCGTGCGTGTGCCACGTGTGCGGGAAGCAGTTCCGCGTCGCCAACGGCCTGCAGCGCCATCTCANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCCCAAAACCTTTGCGAACACTCAGAACTTGAAGCAGCACCTGCGCATCCACACCGGAGAGCGGCCGTTCATCTGCAGCCACTGCGGCAAGCGGTTCAGACAGCGGGGCTCGCTGCACGTGCATCTGAAGGTCCACACTGAACAGTTTCCCTACCAATGTGCGGATTGCGGAGAAAAGTTCAGATTGCGCGCCGGTTTGGTCCGACATCGATTGAAGCACACCGGGGAGCGGCCGCACGCCTGCCTGCTCTGCGGGAAGACGTTCCGACAGAAATATGAGCTGAACAACCACAGATTAATACATTCGGACAGCAAGCCGTTCGCGTGCTGCATCTGTGGCGCGACCTTCAAGCAACGGAGGACTCTGCGGCACCATACTAAGAGGGTCCATGAAACTGATGGGACCCGGGAACCGACTCATCCGCTAGTACTGTTTACAGAAAAGCAAGATATCAAAATAGAAGTGGACGAAGACACAGACAGCTCAAACTTAGTTAAAATCTTTGAAAATATCGAAAAGCCCACCACCATCACTGTAGACGAAGATGGGAGGCGATTTGGAACCTGCAAGGTGTGCAACAAGGCTGTCAGGTTGACCTCCTGGCACCGGCACTCGCGGAGCCACCAGGCCAACCGACGTTACAGCTGCCACACCTGCGGCTTGGGGTTCAACGACAACGGGAACCTGGCCCGCCACAGGCGCGCTCTGCACGCGAAACAACGACCCTACTCCTGCCCCATATGCCAGAAAAGCTTCTCAAGGAATAGCCATTTGGAAGATCATGTGAAATCCCATTCGGAAAGCAGGGAGTTTGTTTGTGTTTTGTGCGGTAAAGCGTCGAAGTCTAGCACAGCGTTGAGGATGCATCGGAAGACGCACGACGCGAGCCGGTTCCAGTGTATGGAGTGCGGAGCCCGGTTCAAGCGGCGGGGGGAGCTGCGCGCGCACGTCACCGTGCACACCGGCGAGAAGGCGCATCTATTCGAGGACATAGCCAACATAGTGGAGACCCTGGCGCCGCCGCAGCTCGCTGCCGCCCCCCCCTCGGACTCCAGGCCCTGCGACTTCTGTGACACGGAGCTCGCGGAGGCTTCCTACAAGGAGCACCTGGTCACGGCGCACGCCGACATGCTGTTCCACTGCGAGGAATGTGACAAATACATCGACAGAAAAGACTTTATACTCCACATGTCGCTACACGCGGTACAATACACCACTGACAACGATAAACGTGATATAAAGAAGATTAAGAAAATGAAAAAGAGGAAGCAGGATGAGAGATCTGATAGCAATACTGATGTGGATAAACGGCCGCCTAAATTTGAGGACCGGCAAGAGAACGAGTTCTCGGACCATAGTGATACTGACTACGGCTTTGGACCACTACCCGAGTCTGTTTTCGAAGCCATAGAGGACTCTCAGGACAGTCAGCCGGCCGATGAAGAACCTATAATTGCAGAATCTGAAAATTGTGATACGAATAGTCAACCCCAAGCCGAAGGGGAGAACACAGAAAAAGTCAAAGTCAAAAGCCACAAGAAGACGAGAACGTGTCCAATTTGTTCCAAAGTGTACACAGCGTCCTCTAGCTACTTCTATCACCTGAAATATTTCCATAATAAGAGCAAGGACCACGAATGTGATGTGTGCGGACGGAAGTTCGGGACTAAGGCCAGTTTGTCGCAACACGCATTGCTTCACTCAGGGGAGTGTCATTACGAGTGCAAAGAGTGCAAGAAACGGTTCAGATCCAAAGCGAGTCTGTACATCCACGAGCAGACCCATAACGGCATTAAATCGTGGAGCTGTCAGCAATGCCACAAGTCGTTTCGCTGGCGGACGCATCTGCTGCGGCACGTGAAGCGGCACTCCGCTGAGAAGGCGCACGTGTGCTCGCAGTGCGGGCGCGGCTTCAGCGTGCGCTGCGACCTGCTGCGGCACTCGCGCACGCACGCCGCCGCCGCCCACGTCTGCGGGCAGTGCGGACACAAGTTCGCACAGCTACGGTACCTCAAAGTGCACATGGACAAGAAACACTTGGACACCGCGAAGGAATCTCATTGCGTGTAA
- Protein Sequence
- MRKGRMDDETRRELSEVQTRINGKVYYTCKICGKNLSSTHTYVFHKRIHTGERPCVCHVCGKQFRVANGLQRHLXXXXXXXXXXXXXXXPKTFANTQNLKQHLRIHTGERPFICSHCGKRFRQRGSLHVHLKVHTEQFPYQCADCGEKFRLRAGLVRHRLKHTGERPHACLLCGKTFRQKYELNNHRLIHSDSKPFACCICGATFKQRRTLRHHTKRVHETDGTREPTHPLVLFTEKQDIKIEVDEDTDSSNLVKIFENIEKPTTITVDEDGRRFGTCKVCNKAVRLTSWHRHSRSHQANRRYSCHTCGLGFNDNGNLARHRRALHAKQRPYSCPICQKSFSRNSHLEDHVKSHSESREFVCVLCGKASKSSTALRMHRKTHDASRFQCMECGARFKRRGELRAHVTVHTGEKAHLFEDIANIVETLAPPQLAAAPPSDSRPCDFCDTELAEASYKEHLVTAHADMLFHCEECDKYIDRKDFILHMSLHAVQYTTDNDKRDIKKIKKMKKRKQDERSDSNTDVDKRPPKFEDRQENEFSDHSDTDYGFGPLPESVFEAIEDSQDSQPADEEPIIAESENCDTNSQPQAEGENTEKVKVKSHKKTRTCPICSKVYTASSSYFYHLKYFHNKSKDHECDVCGRKFGTKASLSQHALLHSGECHYECKECKKRFRSKASLYIHEQTHNGIKSWSCQQCHKSFRWRTHLLRHVKRHSAEKAHVCSQCGRGFSVRCDLLRHSRTHAAAAHVCGQCGHKFAQLRYLKVHMDKKHLDTAKESHCV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01180486; iTF_01179660;
- 90% Identity
- -
- 80% Identity
- -