Pobe047657.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Phasia obesa
Gene Symbol
grau
Assembly
GCA_949628195.1
Location
OX451219.1:107613808-107615672[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.4 60 6.0 0.3 3 23 263 284 262 284 0.93
2 9 1.6e-06 0.00025 22.9 3.1 1 23 317 339 317 340 0.96
3 9 0.0002 0.031 16.3 1.7 3 23 350 370 348 370 0.95
4 9 3 4.6e+02 3.2 0.2 2 23 379 403 378 403 0.87
5 9 0.018 2.8 10.2 0.7 3 23 410 430 409 430 0.97
6 9 0.28 42 6.5 0.2 3 23 440 463 438 463 0.80
7 9 0.039 5.9 9.1 7.1 1 23 468 491 468 491 0.97
8 9 6e-06 0.00092 21.1 0.4 1 23 496 518 496 518 0.97
9 9 0.0002 0.03 16.4 2.5 1 23 524 547 524 547 0.97

Sequence Information

Coding Sequence
atgatttGTTTTGTATGCACGGAGAACGCTGATCAAACTTTAGCAATATTTGGTGAAGACAATGTTAATTCTAAAATTGCAGCAATGATTGAAAAACATTTATgtctaaagCCTCAGGAAAAGGAGGAACAAAAAATCTTGGAAATATGTGTTAAATGTTTGGAAAAACTAAGAGATTTTAACGAGTTTTTCGAATTTGTTGCAAAAGTTCATAATGAAGAAACGAAATGCTTGCAAGGGTTACTTTTAGAAGATACGGGCGGCTTAGtttcgcaaaaaaatatatgggatACTAATATAAAAACGGAAACATTGGAGGAAACGTTGAACAATAATGTAGAATTACATTTTCTGGAAACGGAAGACGCATTTACCGAAAATCCGCTGTTAGACCTTGAACCGGAAGAGGATAATGACATGgaagattttataaatattgatataaaaacCAAGAATGAGAAACCCAAAGCCGCAAAgacaaaaaaatcacaaaaattgaTGAAGCGAGCTAAAAGTTCTGAATCAAGCGACAGTGATGATGAAAATGAACAGTCATTAGCGTCCCTTTTAGATGAGATTAAGAATGAAGATAGTGAGGAAACCTTAGATACAAACAATGAAATAAGGGTTGGTTCCGAAAAGAAAAAGAGGCAAAGAAGAACATTATCTCGATCAAAAAGCAAACGgtctaaaaaaattgataaaccTAATGAACCTAAACGTAGAAAGGGTCATGTTTTATTAGAAGAAAATGATAGTCTTATTAAAAAGCATATAAAAATGCTATGTCAAATGTGTTCATTTATAGGAGAAGATTTCTCAAACCTTATAAAACATTACAAAGATGAGCATGTAGGTGTAAAACCCTTTATAAAATGCTGTGAGCGTAAATTGGATTGTCCGTCGGATATTTTACAACATGCTTATTTTCATGAAGATCCTGAACACTTTAAGTGTCAAGAATGcggtaaaacttttataaacaattccGGGCTAAAGGATCACTTTATGAAACATCATGAACCAGAAGAAAATCTGCCATATGGCTGTGATGAATGCCCTCGTcgattttcaagaaaaaatctGCTGGCTCATCATAAAGCTAAACATATACCGAAAACGGAAAGATCACATTTTTGCCAAATATGTGCACCGCCGAAAGCatttgccAGTGAGTATATATTACAGATTCATATAAAGTCACGTCATAAGAAGGCATCAAATATTTGTCATGTATGCGCTAAAGAAATACGAGATAAACAAGCGTTTGAAAAACATGTACGGCTACATTTTGAGACAAGTGGACCACGTATTAAATGTCCCCGAGAAGGCTGCGAAAGTTGGCTAAAGGATGAAGACAATTTAAAACAGCATTTGAGACGTTTCCATAATCAATCCAAATACGAGTGTCCTGAATGTAGTcgaatatgtaaaaataaacattcttTAACCTGTCATTTAAGAAACACACATTCCACGCAAATATTTACATGTGAAGAATGTCAAAAGAGTTTTAAAAGCGCTTTGTcattaaaggaacATATGGCGGGTCACACTGGAGAACCTTTATACAGTTGTCCGTTTTGTACGAGAACTTTTAATTCCAAGGCAAATATGTATTCACATAAGAAAAAAGCTCATCCCATAGAATGGGATTTAgttaacaaatcaaaaatgggttttatataa
Protein Sequence
MICFVCTENADQTLAIFGEDNVNSKIAAMIEKHLCLKPQEKEEQKILEICVKCLEKLRDFNEFFEFVAKVHNEETKCLQGLLLEDTGGLVSQKNIWDTNIKTETLEETLNNNVELHFLETEDAFTENPLLDLEPEEDNDMEDFINIDIKTKNEKPKAAKTKKSQKLMKRAKSSESSDSDDENEQSLASLLDEIKNEDSEETLDTNNEIRVGSEKKKRQRRTLSRSKSKRSKKIDKPNEPKRRKGHVLLEENDSLIKKHIKMLCQMCSFIGEDFSNLIKHYKDEHVGVKPFIKCCERKLDCPSDILQHAYFHEDPEHFKCQECGKTFINNSGLKDHFMKHHEPEENLPYGCDECPRRFSRKNLLAHHKAKHIPKTERSHFCQICAPPKAFASEYILQIHIKSRHKKASNICHVCAKEIRDKQAFEKHVRLHFETSGPRIKCPREGCESWLKDEDNLKQHLRRFHNQSKYECPECSRICKNKHSLTCHLRNTHSTQIFTCEECQKSFKSALSLKEHMAGHTGEPLYSCPFCTRTFNSKANMYSHKKKAHPIEWDLVNKSKMGFI