Basic Information

Insect: Pediculus humanus
Gene Symbol: -
Assembly: GCA_000006295.1
Location: NW:50807-56352[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 31 0.095 6.4 6.8 0.9 3 23 59 80 57 80 0.94

2 31 0.047 3.2 7.7 2.4 2 23 87 109 86 109 0.91

3 31 0.00065 0.044 13.6 0.4 3 23 296 317 294 317 0.95

4 31 0.22 15 5.6 0.8 2 19 324 341 323 344 0.91

5 31 2.7 1.8e+02 2.2 4.1 1 23 356 378 356 378 0.97

6 31 0.0033 0.22 11.3 1.9 1 23 500 523 500 523 0.92

7 31 1.7e-05 0.0012 18.5 0.8 1 23 541 564 541 564 0.94

8 31 4.2e-05 0.0028 17.3 0.6 1 23 581 604 581 604 0.93

9 31 0.92 62 3.7 2.8 1 19 636 654 636 659 0.90

10 31 2.9 2e+02 2.1 0.6 3 23 699 720 697 720 0.89

11 31 0.056 3.7 7.5 0.1 2 23 727 748 726 748 0.96

12 31 0.00012 0.0078 15.9 0.5 1 23 756 778 756 778 0.97

13 31 0.09 6 6.8 0.1 3 23 852 874 852 874 0.93

14 31 0.0019 0.13 12.1 0.7 1 23 877 900 877 900 0.97

15 31 0.00024 0.016 15.0 0.3 2 23 907 929 906 929 0.96

16 31 0.024 1.6 8.7 0.6 2 22 957 977 956 977 0.93

17 31 0.11 7.6 6.5 0.1 2 20 992 1010 991 1012 0.91

18 31 0.012 0.83 9.5 2.2 2 22 1027 1047 1026 1047 0.93

19 31 0.02 1.3 8.9 0.5 2 23 1065 1087 1064 1087 0.90

20 31 7.5 5e+02 0.8 1.0 2 19 1091 1112 1090 1117 0.82

21 31 0.08 5.4 7.0 1.2 3 23 1125 1147 1124 1147 0.92

22 31 0.44 30 4.7 1.6 2 23 1155 1177 1155 1177 0.94

23 31 0.0012 0.081 12.7 0.3 2 23 1245 1266 1244 1266 0.96

24 31 0.18 12 5.9 1.3 1 23 1281 1304 1281 1304 0.95

25 31 5.2 3.5e+02 1.3 1.9 3 23 1312 1333 1311 1333 0.80

26 31 0.042 2.8 7.9 0.5 2 23 1339 1360 1338 1360 0.97

27 31 2.8 1.9e+02 2.1 0.2 2 23 1370 1392 1369 1392 0.92

28 31 1.1 72 3.4 1.3 1 23 1430 1453 1430 1453 0.96

29 31 0.42 28 4.7 0.3 1 23 1482 1505 1482 1505 0.94

30 31 0.81 54 3.8 0.3 2 23 1514 1536 1513 1536 0.93

31 31 0.072 4.8 7.2 0.3 3 23 1543 1563 1540 1563 0.87

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	31	0.095	6.4	6.8	0.9	3	23	59	80	57	80	0.94
2	31	0.047	3.2	7.7	2.4	2	23	87	109	86	109	0.91
3	31	0.00065	0.044	13.6	0.4	3	23	296	317	294	317	0.95
4	31	0.22	15	5.6	0.8	2	19	324	341	323	344	0.91
5	31	2.7	1.8e+02	2.2	4.1	1	23	356	378	356	378	0.97
6	31	0.0033	0.22	11.3	1.9	1	23	500	523	500	523	0.92
7	31	1.7e-05	0.0012	18.5	0.8	1	23	541	564	541	564	0.94
8	31	4.2e-05	0.0028	17.3	0.6	1	23	581	604	581	604	0.93
9	31	0.92	62	3.7	2.8	1	19	636	654	636	659	0.90
10	31	2.9	2e+02	2.1	0.6	3	23	699	720	697	720	0.89
11	31	0.056	3.7	7.5	0.1	2	23	727	748	726	748	0.96
12	31	0.00012	0.0078	15.9	0.5	1	23	756	778	756	778	0.97
13	31	0.09	6	6.8	0.1	3	23	852	874	852	874	0.93
14	31	0.0019	0.13	12.1	0.7	1	23	877	900	877	900	0.97
15	31	0.00024	0.016	15.0	0.3	2	23	907	929	906	929	0.96
16	31	0.024	1.6	8.7	0.6	2	22	957	977	956	977	0.93
17	31	0.11	7.6	6.5	0.1	2	20	992	1010	991	1012	0.91
18	31	0.012	0.83	9.5	2.2	2	22	1027	1047	1026	1047	0.93
19	31	0.02	1.3	8.9	0.5	2	23	1065	1087	1064	1087	0.90
20	31	7.5	5e+02	0.8	1.0	2	19	1091	1112	1090	1117	0.82
21	31	0.08	5.4	7.0	1.2	3	23	1125	1147	1124	1147	0.92
22	31	0.44	30	4.7	1.6	2	23	1155	1177	1155	1177	0.94
23	31	0.0012	0.081	12.7	0.3	2	23	1245	1266	1244	1266	0.96
24	31	0.18	12	5.9	1.3	1	23	1281	1304	1281	1304	0.95
25	31	5.2	3.5e+02	1.3	1.9	3	23	1312	1333	1311	1333	0.80
26	31	0.042	2.8	7.9	0.5	2	23	1339	1360	1338	1360	0.97
27	31	2.8	1.9e+02	2.1	0.2	2	23	1370	1392	1369	1392	0.92
28	31	1.1	72	3.4	1.3	1	23	1430	1453	1430	1453	0.96
29	31	0.42	28	4.7	0.3	1	23	1482	1505	1482	1505	0.94
30	31	0.81	54	3.8	0.3	2	23	1514	1536	1513	1536	0.93
31	31	0.072	4.8	7.2	0.3	3	23	1543	1563	1540	1563	0.87

Sequence Information

Coding Sequence: ATGTTTaacttggaaaattattatgactTTTACGAAACATGCATCAGAGCTCAAACACTTTTACAGAGTAAACTTGGTGATGGCGGCGATGCGACAGCGGTTTGTGCCCCGATTATTAAAGAAGATACTGGTGGCATCGGAGGAGTAATACCCAACTTGGAaagaCTGGTTCATTGTGATCTGTGCTCCGCTTCATTCACAACCGCCAAGGACAGGTGGACCCACGTTTTGCGAACTCACAAAGGTGATCCTAGAATAACGTGTACGTTTTGTCGAAAGAGTTTCAGTACCATATCCGCGCTAAATTTTCACAAGAAAAATAAACATCCAGAAGAAATGGACGAGCTTGAAAAAAAGCTGAAACCACTTCCGAAGCTTCAAAAAATCAACGAAATCCCCAAAATCCAAAATAAAACATACGAAACGGTTCGAAATTTTCTAAACAATAAGACTGAAAACATATTACAGGATGCCAGGCATTCGGATTTAgcaaattttaatgtaaaaattggTAATACAGACATTAAGTTCGGAAACGCGAGCATCACAGTCGGAAATACGGATATTCGCGTCGGCAATTCCGGAGGGGTTAGTGAAAACAGAGCGAGCGAAAATCAATCGATGATAGATAGATTGAAAAATTTAGGTGTCGACGTGTTTACTGGAAATTCCAAAACTAACGATTATAATTCCGAAAGTTTATACGGACACGAGAACGTTGAACACCACAGGcgaaaagttcaaaaaaaacaaaaaatttactcatcGAGTGACGAACAAAATGCGACAGAGTTTCAAAATCCTGAAGACTTGCTAGAACTGGACATGGATTTGGAGGGAAATGACAACGTTGAGAACATTGTAGAATCTGAGAGTATATTCGGTTGCGAAGTATGTTTTCGCGACTTTAAGGATCGGTCTTCGCTATGGCTGCACATGCTGTATTCTCATAAAGTTGAAGCAGGGTGTACTTGTGGAATATGcctgaaattattttccaattaTCACGAATTAGCATTACATGGGAATCTCTGCAAGGATCAAatagaaagtgaaaaaaggaGGTACTACTGCAAAATTTGCTATAGGCAGCACGATTCcaagaaaaaattagaatcGCATACTTcaattcataatttaaatgacgattttattaaagaaaatttcgatttaaataatttgatatcGTCAAACCCTACCATgactgaaaaaataaaattagaggACTATATGGAAGCTGATGTGAGCGAATATTCGGATACGTATTCGCAAGAGCTCGATATTACCAATGACTCAACACAACACAGCATGACTGGTAACGGATATCCCAATGCAGGACAGCAGTATTTTGACGAAGTACAAAGTTATAGAGATCAATTAGCCTATCAAAACTTTTTAGAAGGATCCGGACATTTTTTAGAGTCCTCATCGTTTTTTGATAACATCAAAACGGAAGAAACAAAAACGGATGCTAATCAATCTGAAGACTTGAATAAATTTCGATGCGACGAATGTTATAGATCCTACGAAACATCTCTACAGTTGACGAAACACAAATACAACGTTCATAGAAATCCGAATAGATTACAATACAGGAACGATTCATTCGGTAATCCCGTTTACGAATGCGAATATTGTGGGCAAACTTATGACTCTCCGAAGCAGTTAACAAAACACCGTTACAACGTTCATAAATTTCCTACCAATGCGGTTCCCATTGACGAAACTGGAAAACAAATGTTCAATTGTTCCGAATGTCCGAGAGCTTTCGAAACTCCCAGGCAGTTACAAAAACATCGTTACAACGTGCACAAAGCCATGAGGAAACCCGCCGGTCAATCGATTCCGGGTTGCGATAGCCCGAGCAGTGTTGAATCTTTCAAACCCGGTTTCCATTACTCATCATTTGATTGTGAAATTTGCGGTGAAAAGTCTACGAGCAAAACGGAACGTTGGAAACACTGTTATAAACAACAtcaaaacgaagaaaaattaGTTTGCTCCAATgaagattgtaaaaaaatcatgcctacggaaaattttcaaaaggaacACATGAACTTTCATGCGATGCAAGGAAAATATCCCATTTGTTGTGAAATTTGTTCGAAACTCTGGACGACGAAAATGGAATTTTGGAAACACGTATCGGGAGTTCATTATTCCCTAATAGGATTAACTTGCGGAGTTTGCATGAGAATGTTTTTGACGCTGGATGAGTTGAAAGCACACATAAAAATCCATGAGCCGTTGTCGGAAGCAGAATTTAATTGTGACATTTGTGGTCGCGGATATTCCTCCAAGCCGAAAATGACACGGCATAGACTGATTCACGAAAACGATCCCGAAAGTGATGAATATAATATATTGAAACATACATTATTAAAAGGTAATaaaccgccgccgccgccggtggaaaaaggaaaatacgaaattttaaatataccgaaaataaatagaaattatGAAAATGATTTGGAAATCATCGAAGTCAATCCGGATGATAACGGTTTGGTGGATTTGGAACACGAAGAAAATACTGACACCCTCTGGTGCGACGTTTGTCCGGACCTTACATTTGCAGACCTTGATGAATTGAGGTCTCACAGGCGTAACATACACGCATTATACCCTTGCGATTTATGTCCAAAATTTTACGGCGGAGTGAGTCATTTGTGGAAGCACACGAATCGTAGTCATAAAAATCATCCCGACATAACGTGCGAGTATTGCGGTAAAACGAGTGCGAGTCGAATTCAGCTCAGAGgacacataaataaaaatcataaggAAATTTTATTGGGTCACGTCGTGTCAGAAGGAGGAAATCCTTTACACGTTTTACCAGATCCGGATCCGACAAACTTAAATTGTCGAAGGTGCGGTCGGGAATTTAGGATTCGTTCTCTCGTACGAAGACACGAGCGAACGTGTTTAACAAAGACTAATTTCGATCCGGATCCAACGAATCTGAATTGTCAAAAGTGTGGAAAATATTATCCCATTCGATCTTTGGTCAGAAGACATGAGAAAGCTTGCCTTAATAGAATCATCAAGGATGTGGATCCGGccaatttaaattgtaaagtTTGTGGTAAAGAGTTTCCAAAACGATCGTATTGTCGGCGTCACGAGCGAACGTGCGGTACAAAGAAAGAACGCACACCGAAGGAGGAGGGTCCCATCGAAATTCACTGCGAATGGTGTCCGAAGCAATTCAACAACAGGCGTGCTTATGCCAGTCACGTGGATTACATGCACAGTTTGGTCACTTGCGAAATTTGCGAAGAGGATGAAAAAGCATCGTTCAGATCAAAAACTGAACTTTACAATCATTGTAAGGAAAAGCACAGCGATCATCCGGATTTGTTATGtacttttgaaaaatgtaGGAGACTTCTTAGAACGAAAATCGATTTGGAGAAACACATGAGAGATCATAAGAATAGAGACAATCCTCCGACTTGCGAATATTGTGCCGACATATTTAAGGGacgtaaaaaattaaggaTTCACATGTTGCATCAGCATAGATCTGAAGAATCGAGGAGATACATCTGTGGTGTTTGCGTGAAAGTTCACGATGATACCGAAAAACTAATTGCTCACGCTTATGAAGCGCACAGTAAAATAATGGAAAGGGATTTCGTTTGCAAAATTTGCGCCAAACAATATAATTGCAATGCTAAAGTATTAGATCATCACAAAAATACTCACGATAGTCAATACAAACCTTGTAAAGTCTGTTTAAGGATTTTCACCGATCAAACTCTATTGGAAGAACATTTACAACAGCACGCGATCGGGGACCGAAGTGTAAATTCGGATTTAGTTACGGACCATCAATGTACGATATGTATGGAGTCTTTTGACACCGTAGTACTCCTTCACGAACACGTCAAAGAAAATCATCCGAACCTGCGAGAAAATTCGTGTTTGATTTGCGGAAAGAAATACCAAAGCATTTACACTTGTTATGATCACATGGAAAACAAACACGGAGGCACTTACCTCACATGCAGGAAGTGTTTAATGTTGTTCACCGATAAAGAGGAAAAGGCTGCTCACATGATGACTCATGGTATTCAAGAAGAAGTTGACGTACTGACTTGCACACTTTGTCGAACGCGCAACGAATCCGAAGAAGCTTTAGAAAATCACATAAAAGAATCTCATTCGGAACTTTTCGACGAGTTGGCCGACCGAAACATGTGTTTGATATGTTCCAAAGTATTAAAGTATAAATATAGCATTTTCTgtcacgtggaaaaaaatcATCCTCAAAACTACTGTTGTAGGGTTTGTTTGATGatttacaaagaaaaagacaagTTGGATGATCACGTGATGAGATTACACACGCGCGATAAAGCAGGGAATCCTCCGGTGTTCGTCCCGAAGACGGCTAGTAGTAAAAAACCCTTGAGTACAAAACGTCCTAAACATATGTGTGCCGTTTGCCAGAAAATAGAAGAGAATACTGACGAGTTAAGAAAACACGTCGAAACGGAACACGAATTCGTTCTCTCAAAGGATATGACCTGTTTCCTTTGCGGTTCCACTTACGCCAATCGAGTCAAAGTAGTGAGTCACGTGAAATTATATCACGGTCCGCCTTACATGTGTTGTCGAGAATgcctaaaaatttttgacaacgAAGACGAATTCGTGGCACACGTTGCCGAACACGAAAATGACGTGACGCTAAAATCTTCCGAAGAGATTTCGAAGAGCGTCAAAAGAAAGAGGAGTTCGACTTTGACGGATCCGTCTCCGAAAAGGTCGAAAGTCGAGGTGAAAGAAGAAATGGAAGAATTGGAGTCCGACATGGATAAAATGGCGAGTGAAAAAGATAACGAAGACAGTTACGTGTGCGAAACTGTCAAAAACCTCAGCGGTGAAGaagaattcaaaattaaaatcaaacacAGTATTGGAACCAAAGATGCAACGGACGAAAGTAAAAGTGGGAAAGTTTTGAAAAGGTTGGAAAATAGGGAAGTCGTGCGAAACGGAGAAGAGAGCAGCGAATTGGAAGGGTCCGATAAGAAAATGGGCAGTTCGGTAAAAGAcatgaaaaatttcacatcGTGCGTAGCTGAATAA
Protein Sequence: MFNLENYYDFYETCIRAQTLLQSKLGDGGDATAVCAPIIKEDTGGIGGVIPNLERLVHCDLCSASFTTAKDRWTHVLRTHKGDPRITCTFCRKSFSTISALNFHKKNKHPEEMDELEKKLKPLPKLQKINEIPKIQNKTYETVRNFLNNKTENILQDARHSDLANFNVKIGNTDIKFGNASITVGNTDIRVGNSGGVSENRASENQSMIDRLKNLGVDVFTGNSKTNDYNSESLYGHENVEHHRRKVQKKQKIYSSSDEQNATEFQNPEDLLELDMDLEGNDNVENIVESESIFGCEVCFRDFKDRSSLWLHMLYSHKVEAGCTCGICLKLFSNYHELALHGNLCKDQIESEKRRYYCKICYRQHDSKKKLESHTSIHNLNDDFIKENFDLNNLISSNPTMTEKIKLEDYMEADVSEYSDTYSQELDITNDSTQHSMTGNGYPNAGQQYFDEVQSYRDQLAYQNFLEGSGHFLESSSFFDNIKTEETKTDANQSEDLNKFRCDECYRSYETSLQLTKHKYNVHRNPNRLQYRNDSFGNPVYECEYCGQTYDSPKQLTKHRYNVHKFPTNAVPIDETGKQMFNCSECPRAFETPRQLQKHRYNVHKAMRKPAGQSIPGCDSPSSVESFKPGFHYSSFDCEICGEKSTSKTERWKHCYKQHQNEEKLVCSNEDCKKIMPTENFQKEHMNFHAMQGKYPICCEICSKLWTTKMEFWKHVSGVHYSLIGLTCGVCMRMFLTLDELKAHIKIHEPLSEAEFNCDICGRGYSSKPKMTRHRLIHENDPESDEYNILKHTLLKGNKPPPPPVEKGKYEILNIPKINRNYENDLEIIEVNPDDNGLVDLEHEENTDTLWCDVCPDLTFADLDELRSHRRNIHALYPCDLCPKFYGGVSHLWKHTNRSHKNHPDITCEYCGKTSASRIQLRGHINKNHKEILLGHVVSEGGNPLHVLPDPDPTNLNCRRCGREFRIRSLVRRHERTCLTKTNFDPDPTNLNCQKCGKYYPIRSLVRRHEKACLNRIIKDVDPANLNCKVCGKEFPKRSYCRRHERTCGTKKERTPKEEGPIEIHCEWCPKQFNNRRAYASHVDYMHSLVTCEICEEDEKASFRSKTELYNHCKEKHSDHPDLLCTFEKCRRLLRTKIDLEKHMRDHKNRDNPPTCEYCADIFKGRKKLRIHMLHQHRSEESRRYICGVCVKVHDDTEKLIAHAYEAHSKIMERDFVCKICAKQYNCNAKVLDHHKNTHDSQYKPCKVCLRIFTDQTLLEEHLQQHAIGDRSVNSDLVTDHQCTICMESFDTVVLLHEHVKENHPNLRENSCLICGKKYQSIYTCYDHMENKHGGTYLTCRKCLMLFTDKEEKAAHMMTHGIQEEVDVLTCTLCRTRNESEEALENHIKESHSELFDELADRNMCLICSKVLKYKYSIFCHVEKNHPQNYCCRVCLMIYKEKDKLDDHVMRLHTRDKAGNPPVFVPKTASSKKPLSTKRPKHMCAVCQKIEENTDELRKHVETEHEFVLSKDMTCFLCGSTYANRVKVVSHVKLYHGPPYMCCRECLKIFDNEDEFVAHVAEHENDVTLKSSEEISKSVKRKRSSTLTDPSPKRSKVEVKEEMEELESDMDKMASEKDNEDSYVCETVKNLSGEEEFKIKIKHSIGTKDATDESKSGKVLKRLENREVVRNGEESSELEGSDKKMGSSVKDMKNFTSCVAE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00362800; iTF_01251345;
90% Identity: -
80% Identity: -