Basic Information

Gene Symbol
-
Assembly
GCA_036936625.1
Location
JAUPFT010000020.1:1252311-1253039[-]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 7 0.065 76 5.8 0.1 3 25 48 69 46 73 0.84
2 7 0.12 1.5e+02 4.9 0.1 3 25 74 95 72 100 0.83
3 7 0.023 27 7.2 0.2 3 25 100 121 98 125 0.86
4 7 3 3.6e+03 0.4 0.0 3 25 126 147 124 149 0.80
5 7 0.023 27 7.3 0.2 3 25 152 173 150 177 0.86
6 7 0.13 1.5e+02 4.9 0.1 3 25 178 199 176 203 0.83
7 7 0.023 27 7.3 0.2 3 25 204 225 202 229 0.86

Sequence Information

Coding Sequence
atGCATTGTGGTTACAGCCTGCTGGCGCGATGTGCATCGCAGTCATCGTTAGACGAATCGTCGCAGCCGCGAGCAGTCGGCGACGCAGATGCGGCCGAAAGCGGTGCGCAGCACGCCGTCACGCTTCTCGACGCGCTTGCGAGCCTGCGCTGCGAAGCCACGCTGTGCGACGTGCGCCTGCAGGTACAGCAGTATACGTTGCACGCCGACGCGCTTGCGAGTCTGCGCTGCGACGCCACGTTGTGCGACGTGCGCCTGCAGGTACAGCAGTACACGTTGCACGCCGACGCGCTTGCGAGTCTGCGCTGCGACGCCACGCTGTGCGACGTGCGCCTGCAGGTACAGCAGCACACGTTGCACGCCGACGCGCTTACGAGTCTGCGCTGCGACGCCACGTTGTACGACGTGCGCCTGCAGGTACAGCAGTACACGTTGCACGCCGACGCGCTGGCGAGTCTGCGTTGCGACGCCACGCTGTGCGACGTGCGCCTGCAGGTACAGCAGCACACGTTGCACGCCGACGCGCTTGCGAGCTTGCGCTGCGACGCCACGCTGTGCGACGTGCGCCTGCAGGTACAGCAGTACACGTTGCACGCCGACGCGCTGGCGAGTCTGCGTTGCGACGCCACGCTGTGCGACGTGCGCCTGCAGGTACAGCAGCACACGTTGCACGCCGACGCGCTTGCGAGCTTGCGCTGCGACGCCACGCTGTGCGACGTGCGCCTGTAG
Protein Sequence
MHCGYSLLARCASQSSLDESSQPRAVGDADAAESGAQHAVTLLDALASLRCEATLCDVRLQVQQYTLHADALASLRCDATLCDVRLQVQQYTLHADALASLRCDATLCDVRLQVQQHTLHADALTSLRCDATLYDVRLQVQQYTLHADALASLRCDATLCDVRLQVQQHTLHADALASLRCDATLCDVRLQVQQYTLHADALASLRCDATLCDVRLQVQQHTLHADALASLRCDATLCDVRL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-