Basic Information

Insect: Papilio protenor
Gene Symbol: MBD-R2_1
Assembly: GCA_029286645.1
Location: JAGSMZ010000055.1:2327533-2339045[-]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 3.3e-14 6.5e-11 42.2 0.0 5 65 731 790 727 798 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	3.3e-14	6.5e-11	42.2	0.0	5	65	731	790	727	798	0.90

Sequence Information

Coding Sequence: ATGGcagttaaaaaatgttgtattgAAAACTGTCAGTCATGCTCGACAAGAAAGGAAGATATTGGGGTAACATATCACAAATACCCCAAAAATGAAAGATTGTGTGACACATGGATAACAATTACACGAAACAAACAATTTGATATAACAACACCATCATATGTGTGCTCGCGACACTTTTGTAAAAGagattttcaaatttacaaggactgtaaatatgttttaaagtcAGatGCTGTTCCTTCAATATTtccatggaataaaaaaacatcaaacatGAACTCAAATGAAATATCTTCTGATGCTGTTAGTGCTGGTGCATCACAGCAAATTGATTTTGAAATAGAAAATCTGGATGCTATAAAGAAATTTATAGAAGATCAAGCGAAGGAGACAGAGATCCAAAAATGTGATGAAATGGCTGGAGCATCAGATAAGAAGATAGATATGGAGGAAAAGGAGAAATTAAAAGATGAATTAACTCCAAATGAAATGCAAGAGGAACCATTAACGGTAGCCACAAGTGTAATGGACCTTATATTAAGCCAATCAGAAGCTAGAATGTTAAGTAAAAAggaagaaaaatgttttgataaagAATGCCTTAGTCCAGAAGAAAAGGGCAATAATATGGCTTTGTCTGTTGGTTCTAAAGTTGAAGCAAAAGATTTTGAAGAATCTTGGCATCGGGCGGAAATTATTGAAGTAGATTATGATGAAATGGAAGTGTTGGTGCACTATGAGAATGCCtctaaaaaacaTGATGAATGGATAAGTGTTAACAGTCCTAGACTGAGACCTGATAGTACCACACCCATCCCTACTACGTCCAATTCTGAGACTGACAATGTGGAAGATCCTATAATGAAGGATGAAGATAAACAAGACgagaaatcaaaattaaaatttgttattggTGAAAGATGTTTAGCACGATGGAGGGATAATCGAAGATTTATTGCTACGATTAATAAAGATTTGGGCAATGGCTCTTATGAAATCATCTTTGATGATGGATTCCACTGGAAGTGTACGACAAGCAGGCTCTTTAAACTGAAAGAAACAGAAAAAATTGATCCCTCAACTGAAGCATTATCATCTTCATCAATATCCCCTCCCATTTCCTTTAAATCCGGTCCTAGTACATCAACTACAGGATCCTTACAAACACCAATTTTCCATACCCACCTCTTTGACCCAACCCGTGATTATTTAGGTTCAAAAAGTGAACGTCGTGAAAAGAAACGAAAGTTgaacataaaagaaatatttaatatcggCCAAAAGAAGAGGAAAATGCAAAGATCACCAAAGGAATCGAATGCGCCATCACCAAAAGTGATGAAACAGGAAAAACCTAAGCCACtacaaaggaaaataaaactagaAAATAGTATTGACATGAGAAATGATATACCAGACGCTCTGGCATCTATAATTGGTACAATCGCCAGTCCAGAAGTTGATATTAAACCAAAAATAGAAGTTGAACCTCCAAATATGGAGATGGATAATAAAGATGACGCAATTAATATTCCGCAGAATGTAGAAAATGTTGAATCTGCTTGTGTCTCAGGTGTTAAGGAAGATACGGAAGTGACAGAACCTAGAAACAGTATTGATCCagtaCTAGAAGAGGaaataaaacttcaaaatTTCGAAGTAATAGATGACAAGAAGCACGAAGAAGTAATTGATCGGATTAAAGAAGCTATCATTAAATTGGAAGATGGTATCACTAAAACGGAAAAGGTAGATTCACCTAAAGTGGAAATACCCGAAGAAGAAGATGAAGACGAAATTAAAGATGAAATAGAAGCGATTCCAGTTGAACTGACTGAAGATGGTTTACCATTACCCGAACAATCGGAAACTACTGAATACgaaagtaaaagtaaaacaaagaaatctgCGTCGCATTTGAAGAGGAATAAGAAATTTAGATTGTTACAGGCGAAGGCAAAGAAGAAGATGGAGAAGGTGGAATGTGAACTAGCAGAGATGAAGCGGCAAGTGGAAGAGATGAGGAAGCAAATAGTGAGGAAGCAGGAGATGCCGGAGAGTTTCATGTTGCCCGGGGAGTGGTGCTGCCGGTGGGTCAACGGGCAGCCAGTAGGCTCAGTCAGCGAAATAGAAAGTGAAATTAATCAAGACCCAAACAGCAAACCACCTTTACCGAGACGAAGTGTTCAGGTGGAAGATAAGCGTTTGCCTGTGGGATGGACGAAGCATATGGTACGACGAAGTTTCGGCAATTCAGCTGGGAAATGGGATGTTGTTTTGGTTAACCCTGAAAACCGTCGGTTTCATACTAAAACCGATATGCGGGCGTATTTAGAGAAGGAAGCAACGGAAGACCTTAAGCCTTACGAGCACGCGTTACTAGATTTCGGCATCCATTTGAAGCTGGCGCGCCGCATGGGCTGGGTGGCGCACAGCGCGCCCGAGGAGCAGGTGACGCCGGTCCCCGCCGGCATGATCAGCTGCAGCTCCCCACTTGCCAAGAGGAAAAAACTTAACCTCAACAGAGTTAAGGGTATAGTCAAGTCAAAAGACAAGAAAAGAAAGTGGAGTGGAGACGCCAAGATACGTCGTATGCACAAACAACGTACTAAAGCTAGCTTACCAGAAACAagcaatgaaaatatttttgattctGCTAATAATGAAGAAACATCTATCGAAAATGCCACTCTAGAAGATGGATAcgTTTTTGTCGGATCTTTAAAAGTCCAAGTCATCGAAAACTTATTACGCTGTCCTGCTGATGGTTGTTTTAAGAACTTCAGAAATAATACACTATTGAAAATGCATATTAAACATTATCACCGAGACTTAAGGAAACTCCTCGGCGCTACGCCTAAAGTTCTAGATCTAGCTTACGCTAGAACTAGACCTACGAAATTAATAATGgctaaaatgaaaagtaaaagAGAAAGCAAAgtgattaaagtaaaattacctAAACCAGCGAAACGTCTCGAAGTTAAGATAGACATGAAAGAATTAGACGCTGAATTGAAAGTTGATATACCGATATCTTCACCACCAGATTTAGGAAGTGTACCAAAAACACAAGATTCACCTAAACTCCGTAACGCTCTCGTGCACAAACCGGTTAAAAGACCAAAAGTCTTACTTCCAGTTAGAAGACTAGATTCGGACAGGAATGAAAACTTTGGAGAACTAGGATTGGAAGCGCGTGGCGGCACGCCAGTTAGTATGCCGGAGGTGCTAGATTTTGAAACGTCAATATCAACTCATACAGTGACAAAaccaatatttgaaataatgagGAAGGATAAGAAACGAAGGGAATTCGCCACTTTCCCTAACATTCAAAGCGAAGACGATGAATGGCACTCAATGAACTCTGATGTAGAAACGAGGTCCAGTTTCCCGGGCTCCGGGACTCCGGACTCGAAGATAATGGATACTAAGACGTCCGTCAACGCGGCGCCCTCCTCGGAGTCCAATGAGGATCAGAAGGAACAAATGTACACGTACACGGAAACGGGCGAGCGCATTAAGATAGTTCAGATGAAGCGCGAGGAGATAATAAACTGCCACTGCGGCTACCGCGAGGAGGACGGCCTCATGGTGCAGTGCGAGCTGTGCCTCTGCTGGCAGCACGCGCTCTGCCACAACATACAGAGGGAGTCGGAGGTGCCAGAGAAGTACACGTGCAGCATCTGCCTGAACCCGTGGCGCGGGCGGCGGTCGCGGCGCTTCGTGCACGACCAGGAGCGGCTGTACGAGGGCGTGCTGGcgggcagcgcgcgcgcctccGAGCCGCTGCGGCGCGCGCACGAGCTCGCCGGCAACCTGCTGCGCGTGCAGGACGCGCTGCACGCGCTGCGCGTCAAGTACTACGTCGCCACGAAAAAGGACCATCCAAAGTTATACCTATGGGCGAAGGACTGGGAGAACACAGAATTAACTATGACACAGGAGAAATTGAATTCGGACTACTCGGATCTCAATATAATGATCCATAACATTGGCAAGGAGAACTTGCCGTTGAAGACTGATGACGTCAGTGAGATGGCGATGGACGTGACGTCAGAGGAGAGGGATATACCTCTCGGCCCTCAGACGTTACTTAGTGGGTTACTCTCGAGTCCCGGAGGCACCTCCTTGGAATTGCCCATTAGTACTTCGGAGCTGGAGAGATTGGCTAAATGTGTTCAAGAGCAGAGCGAGGTGCGCGCGCCGCAGCCCGAGGCGGCCATCGAGAGCGGCGCGTGTCGCGAGCGCCTGCTGCGACACATACAGCGCTGCCAGGCGCTGCTCGACTCCCGCCTTGACTCCATAGAGGCGCAGGTCGCGGagTTGGAATCCCAAGACCCGTTATTCGAGGACGACGAGACGGCGGAGTATTTCCCGCGCACGAAGCAGACCATACAAATGTTGCTGCGCGACCTCGACACTATGGAGGAACTCGGAGTCATTACATAA
Protein Sequence: MAVKKCCIENCQSCSTRKEDIGVTYHKYPKNERLCDTWITITRNKQFDITTPSYVCSRHFCKRDFQIYKDCKYVLKSDAVPSIFPWNKKTSNMNSNEISSDAVSAGASQQIDFEIENLDAIKKFIEDQAKETEIQKCDEMAGASDKKIDMEEKEKLKDELTPNEMQEEPLTVATSVMDLILSQSEARMLSKKEEKCFDKECLSPEEKGNNMALSVGSKVEAKDFEESWHRAEIIEVDYDEMEVLVHYENASKKHDEWISVNSPRLRPDSTTPIPTTSNSETDNVEDPIMKDEDKQDEKSKLKFVIGERCLARWRDNRRFIATINKDLGNGSYEIIFDDGFHWKCTTSRLFKLKETEKIDPSTEALSSSSISPPISFKSGPSTSTTGSLQTPIFHTHLFDPTRDYLGSKSERREKKRKLNIKEIFNIGQKKRKMQRSPKESNAPSPKVMKQEKPKPLQRKIKLENSIDMRNDIPDALASIIGTIASPEVDIKPKIEVEPPNMEMDNKDDAINIPQNVENVESACVSGVKEDTEVTEPRNSIDPVLEEEIKLQNFEVIDDKKHEEVIDRIKEAIIKLEDGITKTEKVDSPKVEIPEEEDEDEIKDEIEAIPVELTEDGLPLPEQSETTEYESKSKTKKSASHLKRNKKFRLLQAKAKKKMEKVECELAEMKRQVEEMRKQIVRKQEMPESFMLPGEWCCRWVNGQPVGSVSEIESEINQDPNSKPPLPRRSVQVEDKRLPVGWTKHMVRRSFGNSAGKWDVVLVNPENRRFHTKTDMRAYLEKEATEDLKPYEHALLDFGIHLKLARRMGWVAHSAPEEQVTPVPAGMISCSSPLAKRKKLNLNRVKGIVKSKDKKRKWSGDAKIRRMHKQRTKASLPETSNENIFDSANNEETSIENATLEDGYVFVGSLKVQVIENLLRCPADGCFKNFRNNTLLKMHIKHYHRDLRKLLGATPKVLDLAYARTRPTKLIMAKMKSKRESKVIKVKLPKPAKRLEVKIDMKELDAELKVDIPISSPPDLGSVPKTQDSPKLRNALVHKPVKRPKVLLPVRRLDSDRNENFGELGLEARGGTPVSMPEVLDFETSISTHTVTKPIFEIMRKDKKRREFATFPNIQSEDDEWHSMNSDVETRSSFPGSGTPDSKIMDTKTSVNAAPSSESNEDQKEQMYTYTETGERIKIVQMKREEIINCHCGYREEDGLMVQCELCLCWQHALCHNIQRESEVPEKYTCSICLNPWRGRRSRRFVHDQERLYEGVLAGSARASEPLRRAHELAGNLLRVQDALHALRVKYYVATKKDHPKLYLWAKDWENTELTMTQEKLNSDYSDLNIMIHNIGKENLPLKTDDVSEMAMDVTSEERDIPLGPQTLLSGLLSSPGGTSLELPISTSELERLAKCVQEQSEVRAPQPEAAIESGACRERLLRHIQRCQALLDSRLDSIEAQVAELESQDPLFEDDETAEYFPRTKQTIQMLLRDLDTMEELGVIT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01144553;
90% Identity: iTF_01148886; iTF_01143890; iTF_01143844;
80% Identity: iTF_01148886;