Prud002767.1
Basic Information
- Insect
- Panzeria rudis
- Gene Symbol
- MBD2
- Assembly
- GCA_956483635.1
- Location
- OY101447.1:21046405-21048413[-]
Transcription Factor Domain
- TF Family
- MBD
- Domain
- MBD domain
- PFAM
- PF01429
- TF Group
- Unclassified Structure
- Description
- The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 2.9e-24 3e-20 73.1 0.0 1 72 9 75 9 80 0.94 2 2 4.2e-06 0.044 14.9 0.0 27 75 196 253 181 255 0.89
Sequence Information
- Coding Sequence
- atgcAAATGAACTCGAATATTTCAATTGAACGTAAGAAAGTAGACTGCAGTGCACTGCCAAAAGGATGGCAAAGAGAAGAAGTTCTACGAAAATCAGGAATCTCTGCGGGAAAAGTTGATGTATACTATTACagTCCAACTGGGAAACGTATAGATAGCAAACTACAATTGGCACGACATTTAGGAGAAATCATAGATATAAGCAGTTTTGATTTtcagaaaggcaagtttatacAACATCTACCATCACCTTCTATATCACTGTACCGCTGCACATCTGGTACATCTGCCTGCAGCACTAGTGGAACTGGTGTAGTAGTTGGTGGCACCAATATAAGCACTACTGCTGCTGGTAGTGCTACTACATTGCCAACTTTGGGTGGTGGTATCACTATAATACCATCACATCATGCATCTGTGGGTCACAATTTAAAGCGCAAGCATAGAATGGGATCTCAAACAgcagtttttaattttccttcCACTTCAATTTCGAGTCATCATAATCTTTTAAGTTCTTGTACAACGATGACGACGATGACATCAACAAATTTGCCACTTAAGCAACAACAATTAGAATTCAGTCGCGCATTGCGAACAGATGTCTCACTGGTGCCTCCTATACGTCAGACTGCCTCCATATTTAAGCAACCCGTAACTGTAATACGGAATCATGAAAACACCAAGACGAAAAGTGACACAAAACAAGGACCACAAGATAAACCGAAGCAATTATTTTGGGAAAAACGCTTAGAGTCAATGAGAGCTTGTCATGAAACTGGTGAACAATTTGATGACATTGTATTGCCTAAGAGTCTTAAACCTTTAGGGCCCAACGTCCATGAACAGACTGTGATGCAATCACTAGCTACAGCTTTACATGTACTAAATACTCCTGTAACTGGGCAAACTGCTtctaaaaatgaatttcaaaaaaacGCCACGGCTTTCATCAATCCTGACCAACCCCTAATGCAAGGTATTCTCATATCAGAGGATGATATACGCCGACAAGAAGATCGTGTGAGTTTTGCGCGAAGAAAGCTACAAGAAGCtttgaaagtttaa
- Protein Sequence
- MQMNSNISIERKKVDCSALPKGWQREEVLRKSGISAGKVDVYYYSPTGKRIDSKLQLARHLGEIIDISSFDFQKGKFIQHLPSPSISLYRCTSGTSACSTSGTGVVVGGTNISTTAAGSATTLPTLGGGITIIPSHHASVGHNLKRKHRMGSQTAVFNFPSTSISSHHNLLSSCTTMTTMTSTNLPLKQQQLEFSRALRTDVSLVPPIRQTASIFKQPVTVIRNHENTKTKSDTKQGPQDKPKQLFWEKRLESMRACHETGEQFDDIVLPKSLKPLGPNVHEQTVMQSLATALHVLNTPVTGQTASKNEFQKNATAFINPDQPLMQGILISEDDIRRQEDRVSFARRKLQEALKV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00331517;
- 90% Identity
- -
- 80% Identity
- -