Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.0018 13 7.0 0.1 19 44 95 120 90 125 0.89

2 7 6.6e-05 0.5 11.6 0.1 21 51 125 155 121 158 0.86

3 7 0.061 4.6e+02 2.1 0.2 22 44 154 176 150 184 0.85

4 7 0.034 2.6e+02 2.9 1.1 4 44 164 204 161 208 0.79

5 7 0.026 2e+02 3.3 0.1 21 47 209 235 206 241 0.85

6 7 0.00066 5 8.4 0.2 23 48 239 263 236 266 0.89

7 7 0.011 85 4.4 0.0 22 46 266 290 261 296 0.85

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.0018	13	7.0	0.1	19	44	95	120	90	125	0.89
2	7	6.6e-05	0.5	11.6	0.1	21	51	125	155	121	158	0.86
3	7	0.061	4.6e+02	2.1	0.2	22	44	154	176	150	184	0.85
4	7	0.034	2.6e+02	2.9	1.1	4	44	164	204	161	208	0.79
5	7	0.026	2e+02	3.3	0.1	21	47	209	235	206	241	0.85
6	7	0.00066	5	8.4	0.2	23	48	239	263	236	266	0.89
7	7	0.011	85	4.4	0.0	22	46	266	290	261	296	0.85

Coding Sequence: ATGTCTAATATGAATAATACAGAAACATTTATAGCAGAACAATATGTCACAGAACCAGATCTTACAACAGTCTGGAGCGTAACCAGTTTCAATAAAATCGATgctatagaaataaatttaactgataattattataacaatgaTCTACTGATTCTGGAGCTACAAGATGAGAATAATCAAGAATCCCTTAATTTCATCCAACGCATGCACCTTAAAACGAATGATGCAGTAACGACTAAAGAACAATTAACAGACAGTAAAATGCAGCTGAAGAACAATACTTCAGAAAAAGAAAAGCGTCTTACATGTTTACAGTGTGCAAGAGTATTTACGAATGTAAGCAACTTAAAACGTCATATCATAACTCATTCTGCAGAACGTCCTCATAAGTGTCCGATATGtgaaaaaacatttaaacaacCAGCTGATTTAAAAACTCATGCACTACTCCATTCTGGAGATAAACCACATGAATGTTCGCATTGTGGAAAACGTTTTGCTCACCCTAGTAATCTAAAAAGACATTTAGTGACTCATAGTGGAGAACGCCCTTACAACTGTACAGAATGTTACAAAACCTATGCAAGATTGGCTCACCTAGagacacatttattaactcATACTGGAGAGCGTCCCTATAAATGCAATATGTGTGAGAAAACTTTTACACAGCAAACACATCTTAAAACTCATATTATGATCCACCTCGGGCAGAAGCCCTATAATTGTGAAGACTGCGATAAAACCTTCACGAACAGCAGTAATTTAAGACGTCATATTCTGAGACATAACctaaatcaaaaatttaaatgcaaGCATTGTTTGAAGGGTTTTACTCAGTCATCAGATCTTAAAGCACATCTAGAAACGCATGATCCTGTCACACCAAACTCATTACGTAATATTCCAAGAATTCTTAAAAGGCCTAATTTATAA
Protein Sequence: MSNMNNTETFIAEQYVTEPDLTTVWSVTSFNKIDAIEINLTDNYYNNDLLILELQDENNQESLNFIQRMHLKTNDAVTTKEQLTDSKMQLKNNTSEKEKRLTCLQCARVFTNVSNLKRHIITHSAERPHKCPICEKTFKQPADLKTHALLHSGDKPHECSHCGKRFAHPSNLKRHLVTHSGERPYNCTECYKTYARLAHLETHLLTHTGERPYKCNMCEKTFTQQTHLKTHIMIHLGQKPYNCEDCDKTFTNSSNLRRHILRHNLNQKFKCKHCLKGFTQSSDLKAHLETHDPVTPNSLRNIPRILKRPNL

Sequence clustering based on sequence similarity using MMseqs2