Plon086992.1
Basic Information
- Insect
- Pachydiplax longipennis
- Gene Symbol
- MBD3
- Assembly
- GCA_036926295.1
- Location
- JAVFKF010000089.1:451077-467606[+]
Transcription Factor Domain
- TF Family
- MBD
- Domain
- MBD domain
- PFAM
- PF01429
- TF Group
- Unclassified Structure
- Description
- The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 9.2e-26 1.2e-21 78.4 0.1 2 73 4 70 3 74 0.93 2 2 0.0019 24 6.8 0.1 28 74 87 146 72 149 0.80
Sequence Information
- Coding Sequence
- atgtctgtcgagaggaaaaaatatgaatgttcCGCTCTTCCGAAGGGTTGGCAGAGGGAAGAAGTAATTAGGAAATCAGGACTTTCGGCTGGAAAAATTGATGTGTATTACTATAGTCCTAGCGGGAAGAAGTTTCGGAGCAAGCCCCAGCTGGCTCGCTACTTGGGAGATGTCCTCGATCTTTCCACATTTGATTTCAGAACAGGCAAAATAAATTCCCTTCTTTTGCGAAAGAACAAGAAGCAGAAAGGGACTCAGTTCGACTACAGCAGAGGGGTGAGGAATGACGCTTCACTGGTGCCTCCCATACGGCAAACTGCATCCATATTCAAGCAGCCTGTCACCGTGTACAAAATGCAGGATGGTAAAGTTAAGTCAGACTTCAAGCATGGGCCACAGGAAAAGCCCAAGCAACTGTTTTGGGAGAAGCGACTGGAAGGACTAAGGGCTTGTGATGTTGGTGGAACAGAGCTTGATGCAATGGAACTTCCTCGAGGTTTGCGTGCTGTAGGTCCCCATGTGAGGGAGGAGACTCTTCTGCAGTCAGTTGCCACTGCTTTGCATGTTTCAGCTCAACCTGTCACAGGACAAACTGGATCACGCTCAGCACTTGACAAGAATCCTGGGGTATTCCTCAACCCAGACCAACCACTTGTTCAGGCTGTGACTGTGGCTGACGAAGACATAAAAAGGCAGGAAGAAAGAGTGTGTGCTGCACGCAAAAAGCTGGAAGAGGCATTGAAGGCACTCCTTGCATAA
- Protein Sequence
- MSVERKKYECSALPKGWQREEVIRKSGLSAGKIDVYYYSPSGKKFRSKPQLARYLGDVLDLSTFDFRTGKINSLLLRKNKKQKGTQFDYSRGVRNDASLVPPIRQTASIFKQPVTVYKMQDGKVKSDFKHGPQEKPKQLFWEKRLEGLRACDVGGTELDAMELPRGLRAVGPHVREETLLQSVATALHVSAQPVTGQTGSRSALDKNPGVFLNPDQPLVQAVTVADEDIKRQEERVCAARKKLEEALKALLA
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01343982;
- 90% Identity
- iTF_01131560; iTF_01212685;
- 80% Identity
- iTF_01131560;