Basic Information

Gene Symbol
-
Assembly
GCA_963855985.1
Location
OY979743.1:11367918-11381398[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 7.9e-05 0.0071 17.7 1.5 1 23 420 442 420 442 0.96
2 18 0.0038 0.35 12.4 0.6 1 20 448 467 448 470 0.94
3 18 1.9e-05 0.0017 19.6 5.6 1 23 489 511 489 511 0.98
4 18 9e-05 0.008 17.5 4.1 1 23 517 539 517 539 0.99
5 18 3.3e-05 0.0029 18.9 5.3 1 23 545 567 545 567 0.97
6 18 3e-05 0.0027 19.0 7.8 1 23 573 595 573 595 0.97
7 18 6.5e-07 5.9e-05 24.2 2.9 1 23 601 623 601 623 0.98
8 18 9.4e-05 0.0084 17.4 6.7 1 23 629 651 629 651 0.97
9 18 9.3e-05 0.0083 17.5 6.5 1 23 657 679 657 679 0.97
10 18 0.00057 0.051 15.0 0.5 1 16 685 700 685 701 0.97
11 18 0.00043 0.038 15.4 3.4 2 23 706 727 705 727 0.97
12 18 0.00049 0.044 15.2 0.4 1 16 733 748 733 750 0.96
13 18 5.7e-05 0.0051 18.1 4.2 2 23 754 775 753 775 0.97
14 18 0.00057 0.051 15.0 0.5 1 16 781 796 781 797 0.97
15 18 0.65 58 5.4 0.3 2 17 802 817 801 818 0.91
16 18 0.0023 0.21 13.0 0.2 2 16 821 835 820 837 0.94
17 18 5.7e-05 0.0051 18.1 4.2 2 23 841 862 840 862 0.97
18 18 0.00049 0.044 15.2 0.5 1 16 868 883 868 885 0.96

Sequence Information

Coding Sequence
ATGAATCCTGAACACCATAGTATGAATACGGGTGGTGGCCAACCTCCTGGAAGTTCGGAGTCGCAGAGCCAGAGAGTTCAATCTGCGCAGCAACAGCAGCAGGGCAATAATTTGCCCGCGACAACCTCTGCGACGGATTTGCGAGTGAATTCCGCGGCCGTGAACGTCGCTTTGTCTAGCGTCGCCAAATACTGGGTGTTTACAAATTTATTTCCCGGACCTATACCACAAGTTTCCGTGTACGGTTTGCCTACTGGCGCCAGGATTGAAAATGGGAAACCAGTCCAGGACCTAGGTCAACATGCTAGCATACTCAATGGTGATCCAAATATCATTTTGGGGCACCATGGAGGCCAACAGCAAGTTACAGTGTCAGCCGCTGGAGCACAACAAATACCTGTATCTCAAATTATTGCAACACAATCAGGACAAACACATGAAGCATTGGTGGCTCACAACCAACAGCAGGAGCTGGCGCAGCAAGCAGCCAACGCTGCTCAGGTCACAGTTAGTGCGGGTCAACCACACCAGCAGGTACCCAATAACCGGGTCGAGTTTGTACAACACCATAACATTGATATGGTAAATCACGTGGGGCATCATTCACAACAACACTTAATGCAGCAGCAACTAATGGCGGCTGCCCGTCCGGATCACTCAAATCAGCagATACAGCTGACAGTCAGCGAAGATGGAATTGTCACGGTGGTGGAGCCAGGAGGCGGCAAACTGGTTGACAAGGAGGAACTCCATGAAGCCATCAAAATGCCCACAGACCACACCCTCACTGTGCATCAGTTACAACAGATCGTTGGACAGCAGGTGTTAGACAGCGTAGTCCGCATAGAGCAGGCTACAGGAGAGCCAGCGAATATACTCGTGACTCACAATCCGGACGGGACAACCTCCATAGAAGCGAGCGCCGGCGAACAGCTCATAGTGAAAGACGAGAAAAGCGTCGGCAAAATCGAGACAGCGCAGTATGCTGAAATCAAGGACATTAAAGGATTAGATTTAAAGAGTGTCAACGCAATGGGGATGGAGGGTGCGGTGGTGAAGATATCTGGAGCCAACGAGCATGACCTTCACGCCATGTACAAGGTCAATGTGGAGGACCTCTCACAACTGCTAGCCTATCACGAGGTGTTCGGGAAACTGAACGCGGACGGGCAGCCTCAGGCTAAGGTGATAAGCGAAGTTGAAGTAGAGGCCGGAACAAGCGCTGGAATGTCAGAAGCGGAGTCCTCGCCAGGCCATCACGCTTGCGATATCTGTGGCAAGATATTCCAGTTCCGATATCAGCTGATCGTCCATAGACGATATCACGGGGAGAGTAAACCATTTACATGTCAAGTTTGTGGTTCCGCCTTTGCCAATCCGGTCGAATTATCAAGACATGGGAAGTGTCATCTTGCCGGGGATCCCACTGAGCGACACACGAAGAGGTTGACGCAGGACAAACCGTACGCCTGCACCACTTGCCACAAGACTTTCTCGCGCAAGGAGCATCTGGATAACCACGTGCGCAGCCACACCGGAGAAACGCCATACAGATGCGAATTCTGCGCCAAGACATTCACCCGCAAGGAGCATATGGTGAACCACGTCCGGAAACACACGGGCGAGACGCCGCACCGCTGCGAGATTTGCAAGAAAAGCTTCACCAGAAAAGAACACTTTATGAACCACGTCATGTGGCACACAGGTGCAACTCCACACCATTGTACATTATGCGGTAAGAAGTATACTAGGAAGGAGCATTTAGTGAACCATATGAGATCGCACACAAACGATACGGCGTTTCGATGCGACCTGTGCGGCAAGTCGTTCACAAGAAAGGAACATTACACCAATCACATAATGTGGCATACCGGCGAGACCCCACACCGTTGCGACTTCTGCTCGAAGACATTCACCCGCAAGGAACACTTATTGAACCACGTCCGTCAACATACTGGCGAATCTCCTCATCGCTGCAATTTTTGTTCTAAATCGTTCACGCGGCGCGAGCACCTCGTGAACCACGTGCGACAACACACCGGCGAGACGCCCTTCCAGTGCGGATACTGTCCCAAAGCGTTCACAAGGAAGGACCACCTCGGCGAGGAGCTAAGCCGTTGCTACTTCTGCTCCAAGTCTTTTATACGGCGCGAGCACCTCGTCAACCACGTGCGACAACACACCGGCGAGACGCCCTTCCAGTGCGGATACTGTCCCAAGGCGTTCACCAGGAAGGACCACCTCGGCCAGGAGCTAAGCCGTTGCAACTTCTGCTCCAAGTCGTTCACGCGGCGCGAACACCTCGTCAACCACGTGCGACAACACACCGGCGAGACGCCCTTCCAGTGCGGATACTGTCCCAAGGCGTTCACAAGGAAGGACCACCTCGGCGAGGAGCTGAGCCGTTGCGTCTTCTGCTCCAAGTCGTTAACGCGGCAGGAAAATCTCGTCAACTATATGCAGTGCAGATACTGTCCCAAAGCGTTCACCAGGAAGGACAACCTCGGCCAGGAGCTAAGCCGTTGCAACTTCTGCTCCAAGTCGTTCACGCGGCGCGAACACCTCGTCAACCACGTGCGACAACACACCGGCGAGACGCCCTTCCAGTGCGGATACTGTCCCAAGGCGTTCACCAGGAAGGACCACCTCGGTAACAAACAACTCTGGCTCCTAGACTAA
Protein Sequence
MNPEHHSMNTGGGQPPGSSESQSQRVQSAQQQQQGNNLPATTSATDLRVNSAAVNVALSSVAKYWVFTNLFPGPIPQVSVYGLPTGARIENGKPVQDLGQHASILNGDPNIILGHHGGQQQVTVSAAGAQQIPVSQIIATQSGQTHEALVAHNQQQELAQQAANAAQVTVSAGQPHQQVPNNRVEFVQHHNIDMVNHVGHHSQQHLMQQQLMAAARPDHSNQQIQLTVSEDGIVTVVEPGGGKLVDKEELHEAIKMPTDHTLTVHQLQQIVGQQVLDSVVRIEQATGEPANILVTHNPDGTTSIEASAGEQLIVKDEKSVGKIETAQYAEIKDIKGLDLKSVNAMGMEGAVVKISGANEHDLHAMYKVNVEDLSQLLAYHEVFGKLNADGQPQAKVISEVEVEAGTSAGMSEAESSPGHHACDICGKIFQFRYQLIVHRRYHGESKPFTCQVCGSAFANPVELSRHGKCHLAGDPTERHTKRLTQDKPYACTTCHKTFSRKEHLDNHVRSHTGETPYRCEFCAKTFTRKEHMVNHVRKHTGETPHRCEICKKSFTRKEHFMNHVMWHTGATPHHCTLCGKKYTRKEHLVNHMRSHTNDTAFRCDLCGKSFTRKEHYTNHIMWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCNFCSKSFTRREHLVNHVRQHTGETPFQCGYCPKAFTRKDHLGEELSRCYFCSKSFIRREHLVNHVRQHTGETPFQCGYCPKAFTRKDHLGQELSRCNFCSKSFTRREHLVNHVRQHTGETPFQCGYCPKAFTRKDHLGEELSRCVFCSKSLTRQENLVNYMQCRYCPKAFTRKDNLGQELSRCNFCSKSFTRREHLVNHVRQHTGETPFQCGYCPKAFTRKDHLGNKQLWLLD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01071806;
90% Identity
iTF_01125661;
80% Identity
iTF_01125661;