Basic Information

Insect: Osmia lignaria
Gene Symbol: IKZF1
Assembly: GCA_012274295.1
Location: NW:426609-435320[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.94 65 3.5 0.5 1 23 79 104 79 104 0.95

2 17 0.091 6.4 6.6 1.9 2 23 117 138 117 139 0.94

3 17 3.2 2.2e+02 1.8 3.7 1 23 145 167 145 167 0.97

4 17 0.02 1.4 8.7 0.5 2 23 173 194 172 194 0.97

5 17 0.11 8 6.3 8.5 2 21 472 491 471 494 0.94

6 17 1.3 94 3.0 1.0 1 23 559 581 559 581 0.82

7 17 0.031 2.2 8.1 0.2 1 23 788 810 788 810 0.94

8 17 0.003 0.21 11.3 0.3 1 23 818 840 818 840 0.98

9 17 0.071 5 7.0 1.1 2 23 935 956 934 956 0.96

10 17 0.059 4.1 7.3 0.5 3 23 968 988 966 988 0.96

11 17 0.0019 0.13 12.0 0.2 1 23 1065 1087 1065 1087 0.98

12 17 0.021 1.5 8.7 0.3 1 23 1178 1200 1178 1200 0.97

13 17 3e-05 0.0021 17.6 0.6 1 23 1206 1228 1206 1228 0.97

14 17 0.0031 0.22 11.3 2.6 1 23 1275 1297 1275 1297 0.97

15 17 0.00051 0.036 13.7 1.7 1 23 1303 1325 1303 1325 0.99

16 17 0.22 16 5.4 2.0 2 23 1416 1437 1415 1437 0.97

17 17 4.7 3.2e+02 1.3 0.3 2 23 1445 1466 1445 1466 0.79

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.94	65	3.5	0.5	1	23	79	104	79	104	0.95
2	17	0.091	6.4	6.6	1.9	2	23	117	138	117	139	0.94
3	17	3.2	2.2e+02	1.8	3.7	1	23	145	167	145	167	0.97
4	17	0.02	1.4	8.7	0.5	2	23	173	194	172	194	0.97
5	17	0.11	8	6.3	8.5	2	21	472	491	471	494	0.94
6	17	1.3	94	3.0	1.0	1	23	559	581	559	581	0.82
7	17	0.031	2.2	8.1	0.2	1	23	788	810	788	810	0.94
8	17	0.003	0.21	11.3	0.3	1	23	818	840	818	840	0.98
9	17	0.071	5	7.0	1.1	2	23	935	956	934	956	0.96
10	17	0.059	4.1	7.3	0.5	3	23	968	988	966	988	0.96
11	17	0.0019	0.13	12.0	0.2	1	23	1065	1087	1065	1087	0.98
12	17	0.021	1.5	8.7	0.3	1	23	1178	1200	1178	1200	0.97
13	17	3e-05	0.0021	17.6	0.6	1	23	1206	1228	1206	1228	0.97
14	17	0.0031	0.22	11.3	2.6	1	23	1275	1297	1275	1297	0.97
15	17	0.00051	0.036	13.7	1.7	1	23	1303	1325	1303	1325	0.99
16	17	0.22	16	5.4	2.0	2	23	1416	1437	1415	1437	0.97
17	17	4.7	3.2e+02	1.3	0.3	2	23	1445	1466	1445	1466	0.79

Sequence Information

Coding Sequence: ATGTCAGGAAGGCTACCTCGATTGCGTGCACTTCGTCCACGACCTCAGCAACTGAAAATTGAACCGCAGAAGGAAAGTAACCTTAAAGAAACTCGACAGGAAGTCGCGATGCGGGAATACGAGTTACAGGAGAGTTCCGAGGAAATTTCATACGATGTCAAAGGCAATAGCTCTGTAAGGAACAGTTTGAAACGTGAACACGAGGGATACGATTGTTCGGGATCTTCGCAAAATTATGAATGTAAAACTTGTAAACCCTCAAAGCCCCTGTCTAATCTTAAAGCGTATCTtgatcatttgaaaaaagaacaCAAACAAAAGggAAAATTTATACGCGATACTGGAAATCGATGTTCCATGTGTTCATATGTTTCCCTAAATTCAAGGGATCTTGAAACTCATCAGAGAGTACATCATTTGAAAAGAAGATTTTTTAGATGTGCTAAATGTTCTTATGTCACGCATGTACGTGCTCGTTACACAAAGCACGTGAAATATCATTCCATGCCAATGATTAAGTGCGATGCTTGTGACTTTCGTACACCGTACAAGTGGAATTTAGACAGGCACACCAGGAATCATGGAGGAGGAGGAGCTTTCCAATGTCGTGCTTGTAATTTTACAGCTGATATCAGGCAGAGTTTAACAGTGCACGAAACCAATCATCACGAACCTCCTGTGAGTCAAACAAATCGCAAATCTAACACACCTTTTGAGCGTAAACCAAGAAATAGCCCTAAGCGTTACAACCAGGTGGGTGCAAGTGATTTTCGAGATTCGTTACACATATCTGGAAGTACAAGCGTGTCGATCAGTCCTGGAGATTCGTACTCGATTTCTGACCAGGCTTTGGAAGATAAAAGAAGTGCAATGGCAAATGCCGAATGTATAGCGTTAAAATGCGAGGAGAAAGGTTGTCAATTTATTACAGCATGGGATTCTGAAATGCAACGACATCTGGCAGAATGTCATGCTCCAATTACACcaaataaatctaaaaaacCACTGCCAATGTTAATACCTTTAAGCCCTGCTAAATCTGGCAGCAGTAACACCAGTGGATCTTCGGCAACATTATTGAAAGTTCCGCGTGTGAGGGTAAGGCCGGAACTTGCACAAATCGCAAGAGACACCGAACTAGCCAAGTTGTATGGAAATAAAGAAGTGAGAAATTTAAAGAAGGATGCAAATAATGCGGcagatttatttgaaaaaaaaaatgcgtCCTTCTTTGATAAGCTAAAGGAAAAGCTTACAACGTCGGCGTCAATTAATAACGGAGTACCAGAGGTAGCTGTAAGTACTACGAACGATTTGAAATGCTGGTGTACTTTTAAAGCTAGTAGCATGGAAGAGCTGGCTTGTCACAAACAAACACACCACACCGCTCTCAGTGTATCTGTGGGTACAACGCGTTGTCCTAAGTGCAGAAGACGTTGCAAAAGTTCGACTGATCTACAAGTGCATATGCAGTGTTGTCACTCGACAAGCAACAATACGTCCATACACAATAGCttagaaaaaatatcaaattgttCAGAACTCCGTGTGACCTCGTATCGCGGTGAATATACATTTCCTGCGCAAACGGATTGGGACATTAATCTCAGCGGACTGAATTCTTCTGGATCATCGGTTGAAGGCACCTCGACGCATCCATGTGGCCGACGGGTATTTAAATGCCCGCACTGTCCATTTTGGGCATCCACCGCAAGTCGTTTTCATGTTCATATTGTCGGTCATTTAAATCGGAAGCCATTCGAGTGTTCCCTATGCGCGTATCGCTCTAACTGGCGGTGGGACATCACAAAACATATTAAACTTAAAGCAGCTAAAGATCCAGTTCATATGACTGCCACGGTACTTATGACGGATGAAACAGGTCGACGGAATTATTCCAAATATAACAAATACCTTGCACAGGTCGAACAACAATCGTGGGACGAACAAAACATGGAGGAGCGTAACgtagaagaaacaaattctGACGAACCACCGACAAAGTTGTTAATAATGAACACCGATGAATATTTACAAACACCCGAACTTACGACTACTCCTATTTCGATAATGTCTTCGAGCGAAGGAAATCATAATGTTAACGCTATTAATATTGGATTAAGGCCACCTCCCCCTCTGAAAGCTGCTGCTAGAAATCGTGGTCAATCGttgcttaaaaataatttgaattctaCAAGTCAGCCGAGTACATCTACCTCTGCTACGAGTTCggaagaaaataaacgtaCAATGTGGAAGTGTAAGCGTTGTAATTTTCGACATTCCAGTAGAGAAACTGTATCGTTGCACGTTAAGTCTCACAGTGAATCGGAGCAACgatacgaagaagaaaaaAATGCATTTAGCTGCGGAGATTGTCCATATTCTGCATCCGATGCCGCTACTTTATCGATGCACCGAGTTCATCATCGTCCAAATTTGGaagcaattttcaaatgttatttATGCCCTTATTACGTTAGCACAAAAgcGGAGCTTTTGGATCATGTTAGACTTCACGGAGAAGAACTTGCTGTTGTACATCAACAGAATAtggattataatttttcacctACTAAATCTAAAACGCAGCAACCATTAGGAGGAGATACGAATCGtatgaaaggagaaaaatctGTAGAACAAGTGATACATATAACAACGCAAAATAACGTGACTTGTATCACAAGTGCCTCAAAAAGTTCCAGTGTACCTCCGCCGTTACTTCTGGATACCCGAGCACTGCCTGAAGCTCCGTTAGTATGGGTGTCCCGACCGGATGGTACACTTACGAAGATGTTAAAATGTCGTCACTGCCCCTTTGTGTCTTCGCGACGTGCCGAAGTTCGAGATCACGAAAGCATGCATCTCGATTCTCCTGGTAATGGTCCTGTGATCGCATGTACCGATTGTAGTTTTACTTGTACACGACGAGAAGTAATGGTCGCGCATATAGACATGCATTCCGGTTCTTTAGGTACCGTTCATTGTTTAGTAGACGATTCGAGGCCAGATTCGCAGCAGTTGATCGATTTGACTGCGCTTCTCGGATTCACGCATTCCCCTGTATTGGGTTCAGAGCCTGATCTACGTGATTCGAGGCTTGTGCATTGTTGCAGTAAATGCCCAGCGCGATTTCTTTGCGAGAAAGAATTAAGAATTCATTTGCGATATCATTCAACGGAATTGGCTTACTCTTGCCAGTGGTGTTCTTACGCTGCTCGACAACCAGCTCACCTTCTAGCACATCAGAAAGCACACTCGACCGAGTACCAAGAACGTACCAAGTACTTGTTATCATTGTACGGTTACTCGCAACGTTATCCACCTCCTACCACAGCTTGCGTCGAAACAAATGGCCAAGGCACAAATAATTCAACGCCTACCGTTGCATGGATCGTAGTAGAAATTACGGAAACTTCGAGTAGCAGTTTCAATGGTAATagtaacaacaacaacaataacaacaacaataacaacaataacagCAATAACAACAACTCAAACCAACGAAATCAAGGAAATCAAGTATTCACTTGTGCCAAGTGTCCGGCTCGTTATTTCAAACTCGATGCTCTGGAGTATCATATGACTTTGCATGGATCCAACAACAGATTCAAATGCACCGAATGCGATTACTCGTCGAAGACAGCTCAGAATTTGGTGAAACATCAAGTGGTTCATCGACGACAGAACGATACGAACGATGTAACTTCGAATCTGAGTCCGCCACCCGATCCTCAGTTTGGAATCTTTATGCGTGGCAATCCGAATTTCGTATACCCTGGTTACTTGAGGAATGGTCgtttgaaagagaaacggtACAAATGTCACAAATGTCCTTCCGCTTTTGAGAAACGAGAACAATATAGAGTTCATTTGACGTTGCACGGAGCGAAACAAAGATATCGCTGCGACACTTGTGATTATTCTGTCAAATATTATGCTAATTACATACAGCATTTGAAGAAGCATCAAGCAAATGCCGAAGCGCAAGCGTCGCGCAGGCAATTCGAAGATGACACGATCACCATCGATGGCGATACAGTTTCCGACAGGGAATCTGTATCTCGTTCAGGAAAGACTCTTAAATCGTCGAATAATTCAGCTGCGACAATGTCTACGAACGGAATATCAATGTTAAATTACGGTGGAGTTCAAGCTTCGAATCAAGACAAGCAGTCTTTAATGTTGTTGCAAAAGAAAGGAATACTGGTATCGTCGAACGACGAAGTGGAAACATTACGGTGCCAAAGTTGTCCGTTTTCCACCTGTGACAAAGAAGCGATGGACGCTCATAAGCGTCGACACGGTATTGAAAGAATGACGCCATCCTGTCCCCATTGCGACTACATCCCTCGGAAAGATGAGAACGTTGGTGAACATATAAGACTACATTTCACAAGACTTTACAAACCGGAATCCTATCTTATTATAGAGCTTTTAACTTTGACAATGAAGAAAATAGCATCAAATggaaaggaagagaaacagAAGGCTGCTGAATTACTTTTTAAGGAGTACGCGGATGGAAGGTTCTTTCCATTCGCTGATACAAATGCATTTGGTAGTCCTTCAAATAGTCACAAGGAAAAGGTTATAGTAGATCCGAATACCGGCGAAACGAAACATCATTTTCCTCTTTAA
Protein Sequence: MSGRLPRLRALRPRPQQLKIEPQKESNLKETRQEVAMREYELQESSEEISYDVKGNSSVRNSLKREHEGYDCSGSSQNYECKTCKPSKPLSNLKAYLDHLKKEHKQKGKFIRDTGNRCSMCSYVSLNSRDLETHQRVHHLKRRFFRCAKCSYVTHVRARYTKHVKYHSMPMIKCDACDFRTPYKWNLDRHTRNHGGGGAFQCRACNFTADIRQSLTVHETNHHEPPVSQTNRKSNTPFERKPRNSPKRYNQVGASDFRDSLHISGSTSVSISPGDSYSISDQALEDKRSAMANAECIALKCEEKGCQFITAWDSEMQRHLAECHAPITPNKSKKPLPMLIPLSPAKSGSSNTSGSSATLLKVPRVRVRPELAQIARDTELAKLYGNKEVRNLKKDANNAADLFEKKNASFFDKLKEKLTTSASINNGVPEVAVSTTNDLKCWCTFKASSMEELACHKQTHHTALSVSVGTTRCPKCRRRCKSSTDLQVHMQCCHSTSNNTSIHNSLEKISNCSELRVTSYRGEYTFPAQTDWDINLSGLNSSGSSVEGTSTHPCGRRVFKCPHCPFWASTASRFHVHIVGHLNRKPFECSLCAYRSNWRWDITKHIKLKAAKDPVHMTATVLMTDETGRRNYSKYNKYLAQVEQQSWDEQNMEERNVEETNSDEPPTKLLIMNTDEYLQTPELTTTPISIMSSSEGNHNVNAINIGLRPPPPLKAAARNRGQSLLKNNLNSTSQPSTSTSATSSEENKRTMWKCKRCNFRHSSRETVSLHVKSHSESEQRYEEEKNAFSCGDCPYSASDAATLSMHRVHHRPNLEAIFKCYLCPYYVSTKAELLDHVRLHGEELAVVHQQNMDYNFSPTKSKTQQPLGGDTNRMKGEKSVEQVIHITTQNNVTCITSASKSSSVPPPLLLDTRALPEAPLVWVSRPDGTLTKMLKCRHCPFVSSRRAEVRDHESMHLDSPGNGPVIACTDCSFTCTRREVMVAHIDMHSGSLGTVHCLVDDSRPDSQQLIDLTALLGFTHSPVLGSEPDLRDSRLVHCCSKCPARFLCEKELRIHLRYHSTELAYSCQWCSYAARQPAHLLAHQKAHSTEYQERTKYLLSLYGYSQRYPPPTTACVETNGQGTNNSTPTVAWIVVEITETSSSSFNGNSNNNNNNNNNNNNNSNNNNSNQRNQGNQVFTCAKCPARYFKLDALEYHMTLHGSNNRFKCTECDYSSKTAQNLVKHQVVHRRQNDTNDVTSNLSPPPDPQFGIFMRGNPNFVYPGYLRNGRLKEKRYKCHKCPSAFEKREQYRVHLTLHGAKQRYRCDTCDYSVKYYANYIQHLKKHQANAEAQASRRQFEDDTITIDGDTVSDRESVSRSGKTLKSSNNSAATMSTNGISMLNYGGVQASNQDKQSLMLLQKKGILVSSNDEVETLRCQSCPFSTCDKEAMDAHKRRHGIERMTPSCPHCDYIPRKDENVGEHIRLHFTRLYKPESYLIIELLTLTMKKIASNGKEEKQKAAELLFKEYADGRFFPFADTNAFGSPSNSHKEKVIVDPNTGETKHHFPL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00762862;
90% Identity: iTF_01122712;
80% Identity: -