Basic Information

Insect: Orthosia gracilis
Gene Symbol: IKZF1
Assembly: GCA_947562075.1
Location: OX387267.1:23026359-23037519[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 20 3.2 3e+02 3.0 0.9 1 23 54 77 54 77 0.94

2 20 0.087 8.2 7.9 4.1 1 23 84 107 84 107 0.97

3 20 5 4.8e+02 2.3 4.0 1 23 191 213 191 213 0.96

4 20 0.0017 0.16 13.2 1.0 2 23 219 240 218 240 0.97

5 20 2.1 2e+02 3.5 1.4 1 23 246 268 246 269 0.94

6 20 0.21 20 6.7 3.4 2 22 498 518 497 518 0.95

7 20 0.086 8.2 7.9 2.6 1 23 615 637 615 637 0.95

8 20 0.6 57 5.2 0.3 2 23 775 796 774 796 0.96

9 20 0.0011 0.11 13.8 0.5 2 23 876 897 875 897 0.96

10 20 0.13 13 7.3 0.3 1 23 905 927 905 927 0.97

11 20 5 4.8e+02 2.3 2.6 1 23 964 986 964 986 0.93

12 20 0.00024 0.023 15.9 4.0 1 23 994 1016 994 1016 0.99

13 20 0.41 39 5.8 1.9 1 23 1100 1122 1100 1122 0.97

14 20 0.024 2.3 9.6 0.6 1 23 1178 1200 1178 1200 0.97

15 20 0.037 3.5 9.0 2.5 1 23 1299 1321 1299 1321 0.95

16 20 0.0055 0.52 11.7 1.1 1 23 1327 1349 1327 1349 0.96

17 20 0.0068 0.64 11.4 2.6 1 23 1439 1461 1439 1461 0.97

18 20 0.00017 0.016 16.4 1.4 1 23 1467 1489 1467 1489 0.99

19 20 0.84 80 4.8 2.7 1 23 1580 1602 1580 1602 0.96

20 20 0.0099 0.94 10.8 5.6 1 23 1613 1635 1613 1635 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	20	3.2	3e+02	3.0	0.9	1	23	54	77	54	77	0.94
2	20	0.087	8.2	7.9	4.1	1	23	84	107	84	107	0.97
3	20	5	4.8e+02	2.3	4.0	1	23	191	213	191	213	0.96
4	20	0.0017	0.16	13.2	1.0	2	23	219	240	218	240	0.97
5	20	2.1	2e+02	3.5	1.4	1	23	246	268	246	269	0.94
6	20	0.21	20	6.7	3.4	2	22	498	518	497	518	0.95
7	20	0.086	8.2	7.9	2.6	1	23	615	637	615	637	0.95
8	20	0.6	57	5.2	0.3	2	23	775	796	774	796	0.96
9	20	0.0011	0.11	13.8	0.5	2	23	876	897	875	897	0.96
10	20	0.13	13	7.3	0.3	1	23	905	927	905	927	0.97
11	20	5	4.8e+02	2.3	2.6	1	23	964	986	964	986	0.93
12	20	0.00024	0.023	15.9	4.0	1	23	994	1016	994	1016	0.99
13	20	0.41	39	5.8	1.9	1	23	1100	1122	1100	1122	0.97
14	20	0.024	2.3	9.6	0.6	1	23	1178	1200	1178	1200	0.97
15	20	0.037	3.5	9.0	2.5	1	23	1299	1321	1299	1321	0.95
16	20	0.0055	0.52	11.7	1.1	1	23	1327	1349	1327	1349	0.96
17	20	0.0068	0.64	11.4	2.6	1	23	1439	1461	1439	1461	0.97
18	20	0.00017	0.016	16.4	1.4	1	23	1467	1489	1467	1489	0.99
19	20	0.84	80	4.8	2.7	1	23	1580	1602	1580	1602	0.96
20	20	0.0099	0.94	10.8	5.6	1	23	1613	1635	1613	1635	0.98

Sequence Information

Coding Sequence: ATGCTACAGCAGATGTCCTCGCCGCCGCGCGCACAAGTCGGCGAGGTCGCGACTATCGTGCGCCACCTTGAAGGCCGCGTCTACGGCGACGTGTCTTCGGAGGCTTCCTCGGACGCCGCCGAAGATTTTGAATTACCACAGTGCAAGATAAGGAGGAATTATAATTGCACCAAGTGCACGTTCTATACGCAGAACCCGCGCGCTTATCTTGTCCACACGCGTGACGCTCACTTCGTCAGACTCAAGATTTATGATTGTCCACACTGTGTTTACGCTTCGAGACATCATCAAAAACTTATAAGACACGTCAAAATGGTTCACGGAGCATCAAAACCTACTGCAACGACTGTTAAAGTGGAAGAACTATCACCTCCCCCCAACGATAACATGGAGCCAGCAGACCGCATCGAAGACATGCTCGAGGAAGTCGAGGACTGCGAGGAGATGATGATAGAAGTTGATGAGGACTCCATGGACCAACCTGATGATGTCGACGGCGACTGCGACAGAAGTGTAGAGTTAGGATCGCCCTATCGTAGGGCACGTCTGTCAAAAGCTAAAGGCAAATTCTTCTCATGCGATAAGTGTAACTATGTCACCCATATAAGAGCTAGATTCACAAAACACGTCAAGTATCATTCGATGCCTATGATCAAGTGTACAATGTGTGATTTTCGAACACCGTACAAGTGGAATTTGGACCGTCACATGAAGAACCACGGTGGAAGTGGAAGTTTCAATTGTTCGATGTGCAACTTCACGGCGGACATCAAGCAGAGTCTGACGGTGCACGAAATGAATCATCACACACCGGCAGCGGGCCAATCGTTGCCGAGTCGCCGCCGCAACCGGGTGGGCGCCAGCGACACGGTTATTGCGGAGTTCGACGCAGCGAGCGCGTTGCTCCCCAAGGAGGAAGAAGGGAGCGGCGACTCGCGGTCCTCACACTCGGTCTCGGACATGGGTCTCCAATACGCAGACAGAGAACTAGTCAGTTGCAAAAGTGATTCCAACGACGGTACAACTGATGCAATCACCAATCGAAAGGAGACTTCTCAAGATGGATACCACCTTTCACCAACCCATAGCGCAGATGAGAAGCAAAAACAAAGCAGAAAGATTCCCAGGCCAATACCACAACTTATACCGTTAAATTCATCAACACCTAACCAAAAACAAACGTGCACTGGTGAACCACCACAGAAAAAGTTCAAGGAATCCGTCGACAGCGATGACTTTTCTGCTGAAAATACCCTCTTACCAGCAAACCCAGCAATAAAAGAGACTGCAGGTCGAAAGAAAAATGAATCTTTTTTCGACAGATTAAAAGAAAGACTGCTTACAGAAACAGGCGAAGAAGGTTCATTGATATGTAAGATCTGTGGATTTGAAAGTAAATGCTTATCAGAACATTCTGTACACGAGAAAAATTGTTCTCCACAAACGAATCGGATCAATGCAAACACGTCGGTTAAAAGTTTAAGTTCCACTCGATGTCAGAACTGTAGACACAGGTGTAAGTCTAGTGCAGACTTGTACATTCACATGCAAACTTGCGGTAAAAGCGAAACGGCCGACCATGACACCACTATAAAAATTGACAATAGTAATGATGGAGTCATTCCAATCCATGAAACAGAGACTGAGCCCCATCCAATGGAAAACGTCGTTTTCGTTTGGAACAATATTAATCATGACCCTAACAAATTTGATATACCTCTAGACATAAATATAAATGATGATTCCACTCTACCAGAAATGCATCGAAGTTTTGATGCTGAGATTGTTGATGACAATGAAAGCATGAATCTATCGCCGAGTCAAGCTATCGGAAGGAAGGTATTTAAATGTCCACATTGTCCATTTTTCTCCACAACAGCATCCAGATTTCACGTTCATATCGTGGGTCACTTAAACAAGAAGCCTTTTGAGTGTTCCCTCTGCAAATATAAATCTAATTGGAGATGGGATATAACCAAACACATTAAATTGAAATCCGCGAGGGATCCCGAGCATAATGAAGCAAAAGTGCTTATGACCGATGAAACAGGAAGAAGAAACTATAGCAAATATAATAAATTCTTAGCAATGCCTGTTTTAAACGAAAGTGGCGAAAATGAATTCCATTACTTGGATCCTAACACCGCAGTCGATAGCACGATGGAAATTGATGAATCATTTAATGATATGTCAGACGTAATGAATGTACAATTTGAAATGCAACCGCTTAACTTACAGACGCAACACATTGAAGATAATTATAACAACTATATTGATAATAGAGGTCTCAACGATATGAAGAAGCCCAAGAAAACATTATGGAAATGTAAAAAGTGCAATTACAAAGATCCCTCAAAAGAAGCGCTTTTAGAGCATGTCCGTGAGCACTCCAGAGCTGAAGGCGTCCATGACGATACAATCAAACCCCCTTTTAAGAAACCTGAAAACAATACTCCCGACCCAGCAGATCTTGCGTATCGTTGTGGGCATTGCAATCAGCTCTCTAATTGGAAACATGTCATCCAGCGCCATTGCCGATTAAAACACGAAGGAGTGATCAAAGTGATAACTACAGTTAAACCAAAACCTGACCCACCAATGAACATCAATGAGATCAATATTGATACTTGCAACAAATGTCCGTACAGAACGAGTGACAAAAAGCTACTTATTGCTCATTTACAACAGCATCAGCCCTCGGCGAATTCTATTTTCAAGTGCTACTTCTGTCCGTTCTTCGTAAAGGATGAGCCAGAATTAATTCAACATCTACTCCTGCACGGCATCACTGATCCAGAAGATTACATCGCAAAAGCAATGGGAACTAAATCTCCAGGACCACCTGAACCGCAAGCTCCTGTTACCACGTCATTAAACTCCACCAAGCGTCACAAATGCATAGAATGTCCATACGAAACAAACAGTAAGTCACAATTCATGTATCACGAACAATTTCATCGACTGCCGGCGGATACGCCTTACAAATGTCCAGAATGCAACTACAGCGTTTCTAAGAGGCACCTGCTGCACCAGCATCTTCGTGTCCACGGCATCGCCACCAAGAGAACTGAAACCGAGGCCGAATTAGAGGCATCAACATCTGCACAAAACAAGACGGATAAAACGGACTTCCATATAAATCTTGATGAAATACCATTTGTCTGGGTTTCCGCTAAGAACGAGTTCCATAAAATGTACAAGTGCCGTTACTGTTCGTACGTTAATGCTATAAAATGTAAAATACCAAATCATGAAAAAATTCATTGCATCGCTTTCGAAAACAGTGATACGACTATTTACAAATGTTTGGAATGCAAATTCACATGTGATAACGCCGGCAGACTCGCCGAACATTCTAAAAATCATGCTGAAATATATGGTCGCATTTATTGTCCCGTTGAATATGATGTGCCCGATGAGGAACAAATCACAAAATTGAGAAAGGTTATAGAAATTGAAAAATCAGCAAATCCAGAAAGTTTCTCAAGAGATGAAAGCACTACGCACGAAAATAGAGAAATAAAATTATTATATTTTTGTCAAAAATGCCCAGCAAGATTTTTTGATGACACCGACCTCGAGGTTCATGAAAAACGTCATAGCTGCGATGAAACATTGACCAACAAATGTAAGAGTTGTGACTTTTCAGTCACCGACGAATTTGAAATTGAATTAGCGGCACATTTTGCTGTGCACACAGATGAATATCACACAAAAACGAAGATGCTTAAATTTGTCCACAACTCACATCCTTTGCACAGGCCACCCGTGCTAGAGCTTGTTCACTGTCCAAGGACTTCACAGATTACCTGGATATCCACTGGCCCAAGTAAAGCTGAACATATTGAAACCCCTATGAAGAAAATGAGTGATTCTAAACACGTGCCAAAACAATATTGTTGCAGACAATGTCCTGCAAAGTTTTTCAAAAGTTCCGCTCTTACCTATCACATGGGGCTGCATGGAGGTGAAGGCGAACATAAGTGCAAGAAGTGCAACTACGCCGTGAAGAACATTGGAAATCTAGCCAAACATGAACTGCTTCACGAAAATGAGAACAAAGGTACAAGTTGCGACTATGAATCTGGTGATGATATGGATTATAAAAATATTCCATTATCAGGCACTGATTTGTTCCAGAGGAAGACTGAGGCTCAGAAAAGAGTTTTAACAGATAAAGATAAGTTAGTTAAGCCGAACGATCATTTCCCGCCTGTCCTACAAGCCGATCCCCAATTCGGTTATCTAATGCATGGTAATCCTGAATTCATATATCCCACGTATCTGAAAAATGGACGCCAAAAAGAAAAACGTTACAAATGCCACAAGTGTCCTTCAGCTTTTGAGAAAAGAGAACAATATAAGATTCATTTATCATTGCACGGTTCCAAGCAAAGATATAAATGTGAGTTGTGCGATTATTCAGTAAAATATTACGCCAATTACGTTCAACATATGCGAAAACATCAAATGAACGATGAAGCTCAAGCTGAAAGGAAGAAAGATAACAATGATTTTACAGAATCAGAACAACAAGAAGACGTAAAGCAAGACGATAGCAGTGATAACATAAAACTTGCAATAAAAACAATGCCAAAAGGAGCTGCTAAGAGCGACTTTCAGCAATTCTCAATTAGCGACCAACAGACGCTAAGACTGCTACAGAGGAGACGGTCAATGAATAATTCTGGAAACCAAAACACTTCTGAAACTTCGCCGATCAAAGAGCGTAAAATGCACATGTGTCTTTTATGTCCCTACACCAATCAACGTCAAGATTCTTTGAGCAATCATTACAGGAGGCACGGTGACACCGACGTCCTGAGCGGAGGCAGTCATAAATGCTCACATTGCGACCTAGTGGTTGTTCAGTCGCATTTCCTTCGGGAACATCTCAAGACACACTTTAACTACCACAAAACTCTCATTCCCGAATGTTTTGTGGCTAGTGAAGCTGTTAGTTTTACTATAACCAAGTTGGATGAAGAAAGTGAATCAGTTGATCTCAAATTAGACATGCAGAACAAGAGTTATGCATCTAACGATGAAAAGATATTTGTGAAAATTAAAACAGGAGAGCTAATGGTGGAATAA
Protein Sequence: MLQQMSSPPRAQVGEVATIVRHLEGRVYGDVSSEASSDAAEDFELPQCKIRRNYNCTKCTFYTQNPRAYLVHTRDAHFVRLKIYDCPHCVYASRHHQKLIRHVKMVHGASKPTATTVKVEELSPPPNDNMEPADRIEDMLEEVEDCEEMMIEVDEDSMDQPDDVDGDCDRSVELGSPYRRARLSKAKGKFFSCDKCNYVTHIRARFTKHVKYHSMPMIKCTMCDFRTPYKWNLDRHMKNHGGSGSFNCSMCNFTADIKQSLTVHEMNHHTPAAGQSLPSRRRNRVGASDTVIAEFDAASALLPKEEEGSGDSRSSHSVSDMGLQYADRELVSCKSDSNDGTTDAITNRKETSQDGYHLSPTHSADEKQKQSRKIPRPIPQLIPLNSSTPNQKQTCTGEPPQKKFKESVDSDDFSAENTLLPANPAIKETAGRKKNESFFDRLKERLLTETGEEGSLICKICGFESKCLSEHSVHEKNCSPQTNRINANTSVKSLSSTRCQNCRHRCKSSADLYIHMQTCGKSETADHDTTIKIDNSNDGVIPIHETETEPHPMENVVFVWNNINHDPNKFDIPLDININDDSTLPEMHRSFDAEIVDDNESMNLSPSQAIGRKVFKCPHCPFFSTTASRFHVHIVGHLNKKPFECSLCKYKSNWRWDITKHIKLKSARDPEHNEAKVLMTDETGRRNYSKYNKFLAMPVLNESGENEFHYLDPNTAVDSTMEIDESFNDMSDVMNVQFEMQPLNLQTQHIEDNYNNYIDNRGLNDMKKPKKTLWKCKKCNYKDPSKEALLEHVREHSRAEGVHDDTIKPPFKKPENNTPDPADLAYRCGHCNQLSNWKHVIQRHCRLKHEGVIKVITTVKPKPDPPMNINEINIDTCNKCPYRTSDKKLLIAHLQQHQPSANSIFKCYFCPFFVKDEPELIQHLLLHGITDPEDYIAKAMGTKSPGPPEPQAPVTTSLNSTKRHKCIECPYETNSKSQFMYHEQFHRLPADTPYKCPECNYSVSKRHLLHQHLRVHGIATKRTETEAELEASTSAQNKTDKTDFHINLDEIPFVWVSAKNEFHKMYKCRYCSYVNAIKCKIPNHEKIHCIAFENSDTTIYKCLECKFTCDNAGRLAEHSKNHAEIYGRIYCPVEYDVPDEEQITKLRKVIEIEKSANPESFSRDESTTHENREIKLLYFCQKCPARFFDDTDLEVHEKRHSCDETLTNKCKSCDFSVTDEFEIELAAHFAVHTDEYHTKTKMLKFVHNSHPLHRPPVLELVHCPRTSQITWISTGPSKAEHIETPMKKMSDSKHVPKQYCCRQCPAKFFKSSALTYHMGLHGGEGEHKCKKCNYAVKNIGNLAKHELLHENENKGTSCDYESGDDMDYKNIPLSGTDLFQRKTEAQKRVLTDKDKLVKPNDHFPPVLQADPQFGYLMHGNPEFIYPTYLKNGRQKEKRYKCHKCPSAFEKREQYKIHLSLHGSKQRYKCELCDYSVKYYANYVQHMRKHQMNDEAQAERKKDNNDFTESEQQEDVKQDDSSDNIKLAIKTMPKGAAKSDFQQFSISDQQTLRLLQRRRSMNNSGNQNTSETSPIKERKMHMCLLCPYTNQRQDSLSNHYRRHGDTDVLSGGSHKCSHCDLVVVQSHFLREHLKTHFNYHKTLIPECFVASEAVSFTITKLDEESESVDLKLDMQNKSYASNDEKIFVKIKTGELMVE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01231174;
90% Identity: iTF_00726922;
80% Identity: -