Basic Information

Insect: Orthosia gothica
Gene Symbol: Zfa
Assembly: GCA_949775005.1
Location: OX459049.1:6025274-6033751[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 22 0.05 10 8.9 2.2 3 23 650 671 649 671 0.96

2 22 0.25 50 6.7 0.3 1 22 1054 1075 1054 1075 0.95

3 22 0.11 23 7.7 4.8 2 22 1150 1170 1149 1170 0.93

4 22 2.9 5.8e+02 3.3 0.0 3 23 1179 1200 1177 1200 0.89

5 22 0.021 4.2 10.0 0.2 3 23 1219 1240 1217 1240 0.96

6 22 0.03 6 9.6 2.0 1 23 1246 1269 1246 1269 0.95

7 22 0.15 30 7.4 0.0 1 23 1295 1318 1295 1318 0.90

8 22 0.023 4.5 10.0 3.4 1 23 1323 1345 1323 1345 0.97

9 22 0.01 2.1 11.0 0.2 1 23 1351 1374 1351 1374 0.95

10 22 0.0048 0.96 12.1 0.8 1 23 1387 1409 1387 1409 0.97

11 22 0.00021 0.042 16.3 1.8 1 23 1459 1482 1459 1482 0.97

12 22 0.0013 0.27 13.8 1.0 1 23 1540 1563 1540 1563 0.96

13 22 0.0028 0.57 12.8 2.1 2 23 1590 1612 1589 1612 0.95

14 22 0.047 9.4 8.9 0.1 2 23 1618 1640 1617 1640 0.94

15 22 0.012 2.4 10.8 0.2 1 21 1684 1704 1684 1705 0.95

16 22 0.0005 0.1 15.1 1.0 1 23 1715 1737 1715 1737 0.93

17 22 0.00013 0.027 17.0 0.3 2 23 1830 1852 1830 1852 0.93

18 22 4.7e-07 9.4e-05 24.7 1.4 3 23 1859 1879 1858 1879 0.98

19 22 0.026 5.3 9.7 0.3 1 23 1897 1919 1897 1920 0.95

20 22 0.15 29 7.4 0.0 1 23 1943 1965 1943 1965 0.97

21 22 0.033 6.6 9.4 0.6 1 23 1971 1994 1971 1994 0.95

22 22 0.00031 0.061 15.8 0.4 1 23 2002 2025 2002 2025 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	22	0.05	10	8.9	2.2	3	23	650	671	649	671	0.96
2	22	0.25	50	6.7	0.3	1	22	1054	1075	1054	1075	0.95
3	22	0.11	23	7.7	4.8	2	22	1150	1170	1149	1170	0.93
4	22	2.9	5.8e+02	3.3	0.0	3	23	1179	1200	1177	1200	0.89
5	22	0.021	4.2	10.0	0.2	3	23	1219	1240	1217	1240	0.96
6	22	0.03	6	9.6	2.0	1	23	1246	1269	1246	1269	0.95
7	22	0.15	30	7.4	0.0	1	23	1295	1318	1295	1318	0.90
8	22	0.023	4.5	10.0	3.4	1	23	1323	1345	1323	1345	0.97
9	22	0.01	2.1	11.0	0.2	1	23	1351	1374	1351	1374	0.95
10	22	0.0048	0.96	12.1	0.8	1	23	1387	1409	1387	1409	0.97
11	22	0.00021	0.042	16.3	1.8	1	23	1459	1482	1459	1482	0.97
12	22	0.0013	0.27	13.8	1.0	1	23	1540	1563	1540	1563	0.96
13	22	0.0028	0.57	12.8	2.1	2	23	1590	1612	1589	1612	0.95
14	22	0.047	9.4	8.9	0.1	2	23	1618	1640	1617	1640	0.94
15	22	0.012	2.4	10.8	0.2	1	21	1684	1704	1684	1705	0.95
16	22	0.0005	0.1	15.1	1.0	1	23	1715	1737	1715	1737	0.93
17	22	0.00013	0.027	17.0	0.3	2	23	1830	1852	1830	1852	0.93
18	22	4.7e-07	9.4e-05	24.7	1.4	3	23	1859	1879	1858	1879	0.98
19	22	0.026	5.3	9.7	0.3	1	23	1897	1919	1897	1920	0.95
20	22	0.15	29	7.4	0.0	1	23	1943	1965	1943	1965	0.97
21	22	0.033	6.6	9.4	0.6	1	23	1971	1994	1971	1994	0.95
22	22	0.00031	0.061	15.8	0.4	1	23	2002	2025	2002	2025	0.96

Sequence Information

Coding Sequence: ATGAATGTGAACTATGATCGTGTTTGTAGACTGTGCTTGTCATCTCGAGGCGAATTACTGCCGATTTTTCCTACCACCAGTTCGGATGACTCGGAACCTCCCGTCCTCGCTTTGAAAATCAAGGATTGTGTGTCCGTACAGATAAACGAAAATGACGACCTGCCCACCAATGTCTGCAGGAAATGCATGGACAATGTCAATAACTggcatgtttttaaaaatgtatgtgaaaggACACAAAACAAACTACAGTCTCTGAAAGATGGCAGCCAACTAGAAGAGgtgaaaataaaaagtgaacCACTGTCTGATGAGGCTTATGATGATGGAGTGGCCATTGATGGCTCATATCCTGTCATTGAGAATGCTGGCTTTTCAAACAAAGTACAACCTGAAGGTCCCCCAATCTTGGCTTCACTGGGGCTCACACCAAGAAGTGATAAGaaatgtgtggATCCGCGAATGGATTGGCATCGGGTCCATGCTATTTTGGACATGGTTCAAGACAATGAGGTGATTGACTCTCTGCAGACAAAGGAAGAGTGTGATGTTTTACAGCGATCTGATCATGACTCTGACTCAGAAGCTGAACTCAAACCTGAAATTGATGACAATTATGTTGATTGCAAAAGCGGTTACatatgcaaaaataaaaaagtaatatcaAAAGCTCCAAAACTATCAACTTCTGTAAACAATGCAAGAATGAAAGATGCTTTCAAACTCAGGAAACGTAAATTGGAAGTCCGTAAACATTGTTCTCGACCTAAAAATGCGTGGCAATTGTTATTCACCGATGACCTACTAGAATTGATTGTTGCTTCAACTAATGACAATATTGTGACAAATGGGAAAAGTTTCTCAGAGTCAACTAGTGTCAGCGAAATTAAAACGCTTATCGGTATTCTGTATCTGCACGGCATAATGCGACCGACGCACCAGAAATGTACTGACCTTTGGAACAGCGAATGTGGCGTTCCTTGCGTCAGAAATGTCATGAAATACGAAAGGTTCAAATTCTTACTTCAAAACATGAGCTTCGATAAAGAGGACGACGACAGCATTATTCAGTTCGACATAATGAAGCGTATGCGCAAGGTATTCGAAATCTTCGCCATGAATTGCAGAACATCTCACGAGATCGAGAATGTCGCGGTTATTGATGAGATCATCGTGCCAGTTTACGGACCTTGCCCATTTCGATACGATATTGATAAGAAGCCGCTGAAGCGGGGCATAAAAATGGTGTTGCTAGTTGATTCATCCACATTCTACATGAGCAATTTAGATGTCATTACTGATCCTTATTTTGGGGCCGAAGAGATAACGAAAAAGTTGGTTCAGCATTTAGCTGGAACTGGCAAATCTATTGTTATGGACAGTTGGTTTACATCTGCCTCGTTGATGGATACGCTTAAAAATGAGTACCAGTTGTATTCCATTGCAGCCCTGCACCCAAATAGTGATATGATTCCACCTCTATTCCTATCTCAATACAGGAAAACTCGATCATTTATGTCTGGGTTTATTGATGATGAAGTATCATTGACATCTTATGTCAATGCTGAGGGAAAATCAGTAAATGTATTGACTAATGAGCCTAGATATTACAGGAAAGGTCATATTAATCACACTACAGTTGTATCGGTGTATAAGAAGACGCAGTCTGCTGTAGAAGTTGTCGATGTTCTCATGCATTACTACACCACAATGCAACACACAAATGATTGGACATTGACTTTATTCTTCACATTGCTGAATATTGCCTCTGTGAATGCTCAAGGTGCCGAGAGCGAAAATAATGAAGAAGACGAGGAAGAAATGAATGAGCCCACACAAAATTTTCCGAAAATGCCAAACATGCCTGAGGTATCCATCACGGTCATGAGGACTACCGGTGAAACCCTTCATGCTCGCCAAGGTATTCATCAACTCGCCTCAAAACTGTGCCTCGTCTGCAATCGCTCCTACAGGTACTCTCACAATGCACGCAGACATGAACTTACTTCTCATGGCTTCGACAGATATACCAACAAAATTACTCCTAAAAAAACCCTCAATCATCTACAACCTAAACTCAGACCGAACCCGTTCAACCCCAAAGCAAGGATGATGCCGAATCCTATTAGTCATAAGATGCAGTTCTTGAAAAAGAATATGCCAACAAAAATAATGCCCATGAATAAAGTTATAACGCCACAGAGACCCATTCCAATAAAGACAACGTCAAAGACACAAAATAATTTGCCTTATCCTCTACGCATTAAAGCACTCAAAGATTTACAAATTAAGAAAAAGGAGCCTCAGATTCTCAAGACTTTGTTAACCTCTAAACCTGAAGTTCTGGTTTCAGAACCAGAAATTCTAAATTCTGGGCCTGAAAGTCCAGAAACATTGATATCTGAGCCTGAAATTGCGTCTTTTCAAGTCGAAGCTATCCTTACGGAACCCGACGCCGACGCATACGATGACCCTCAACAAGGTGACGAAGAAGTTGATGAAGAACTGCAAAACAATCAAAGTCAAAACTATGACACAGTCGATATGGACTCTGACAATGAAATAGAGATTGCTCGTCAACAAAGCATTGAACAAGAAGGTGAAGAAAATGCTGAAGGGGAAGAGAATATCGACCATGATGACGATAATAATGAAGCCGGTCAGAGCGATAATGAGAAAGATGGTAATGACGATACAGCTGAAGTACAAGAGAACATGGAAGAAGAAGATAGTGTTGATATTAAACCTGGAGATCATATAAAAGACGACGAGGACCAAGAGGACGGAGAACATGAAGAAGTAGAGATGAATCATAATGAGGACGATGAAGACGACGATGAGCTTCCAATAACATTAGCACCAGTCGTTGAGATAAATGAGGGATTGCAATCCAACTCGTTTAACAGCCAAGCTAATGAAGAAGACGAGGAACTTGACGAAACTGTCGATCCTAATGAAACCATCGAAGATGTGGAGCAGGTTAAAGAACTTGACCCTGACAAAACATATGTTACAAAAACCCAAAGAGACTTCATTCAAAAATATCGCGACATCATTCAGCAAATCAACACGAAGCGATGTTTATGTTGTGATCGCGAACATCCGCGCCGAAAAGCTGTCATACAACACTTGCAGAAAAACGGACACAAAGTGCCAAAACACACTTGTTACAATTGTGTCATCACGTTTGGACATATTGGCGCACTACTCAGTCATATGAGGTCCAATTCTTGCACAAATTTGTGGAAGATTATTTACAATGAAAATGGCATTACCGACGACTTGGTTCTCGAAGATGAGCCGAAGGAGGTCAAGGTTGCTTACAAAGATATTTTCAATGCTAGGTCATACGCTTGCAAGCTCTGCCCAGCCAAATTCCAACTGAAACAGTTTATAATGAAGCATGTATCGGATACGCATGAAGATGGACAGTCTAGGGTACCGCTCTGTTGTGTCCACTGCCGTTCCAGGTTCAAAGAGAAGAGTTTACTCAAGAAACACATTCGTAAAGGCGATTGTACCGTTTATATTGCTTGTGATCTGTGCCCGGACACATTTAGAAACATGCAGGACTTTAACGACCATGCGTTAGCCATCCACGCTGGCAGTTTCGATGATAACCAGAGCAAATGTGTTGATGGTCGGCCAACAGACTGTCCGCTGTGCGGAAAGAAAAACAGTAGTTATCCGAATTTAGTGAAACATTTGAAGATTATTCATGCTGAGGAGAAACCTCACTACTGTCAGCATTGCGACGATAAATACGAACAAGCTGCTGATTTGAACAAACACATTTACATGGAGCATTCCGACAGAACTTTAGGCATGCCGCCCGCGGAGCCGGATATGTCCTTAGTGAAGGAAGAAGCAGAGGAGTATCATTATTCCTGTACGGAATGTAATGCTATTTTCGAAACTGTTGATGCGTGGACTGATCACCAAGTTGCAGAACATAACCAAGTGGCCCACCACTGCGACCAGTGTGAGAAGAAGTTCCTGCGTCCGTCAGAGCTGGCCGAGCACAAGAACACGCACTTGAGGGTTAAGTTCTATCCATGCAGTGTATGTCCCAACTCTTATAGTACTCCACAGAAACTGTCGGAGCATGTGCAACAGTCACATCCAGGAATTGGTGCAGTCGCGGCAGCCGAGTCGGAGTTCTTCTGTGACATCTGCATCAGGGCATTCAAAAGTCGCCAAGCGTACTCGAATCATATGCGTATTCACGCTAAAGTACCTACTACTAACAGGAAACCGGCTCCAATTAAAGAAGGCTTTGCACCCCAAATTATCGGCAAACCCATCAAACAATATCCAATGGTTCAACCTGGGTTTGTATCATTTAAACCTAATTACAACATCCCTAACGCTCCATATTCTTGTGACATTTGTGGTAAAGGATTCATGCACAAGAAAAATATATGGAAACACAAGAAAGTGTTGCATGCCGATATTTTAGTTGATAGACATGATAGTGAAGAGAACACTATGCAAGCATCCACTGAAGAAGAGGAATTTAACCCTGATGAGAACGGTGCCATCCTCTCTACGCCACAATTTAATAGTTTCAACTTTGCGAACTTGAACAATGCACAACAAACGCCTCCAGAAATGACTTATGAATGTGAATTATGTAGCAAACGGTTCCCGCTTAGGACCAGTTTGTGGAAACACAAGCGTGCTAAACACGGAATTGTGAACCCCAGCACTAGTGGTAGCAACGATGTATCCCAGCCATCCGCCAGCGGGGAAGGCAGTAGTAGATCTAGCTGCACTATATGTAGAATCACATTTTCGGATAAGAAATCTTACTATCGCCATCGAAAGAATGTCCATAAATCTACTGTTCAAATGTGCAAAATATGTGGCAAACCGTTAAGTTCAACTTTGGAACTATACGAGCACTTGAAAGCCGCTCATGCAAGGGAATTACTGGGTTACAACGCCAACCAAGGCTCCAGTAAATCACAAGATGTGCCACAAGACATGGAACCTGATTATGATAATGATCAGGAATCTGTCGACCCAAGCGTCGATTACCAAGCGCGCTACCCGTGCGATACTTGTGGCAAACAATTCGTTGGTCTGCTAGCGTTGCAGAACCACCAGTGCATCAACCAGGTGTCATCACAACCACAGACGTTTGACTGCGAGATTTGTCACAAGAGCTACACTTCAATATCTGCATTAAAAAGCCATCGTGGATGGCATTTACGTTCGCCCGATGGCAAGGCAGCCGCCAATAACTCTGGCCTTTGGATGCCTCAGCACAAAGTTACCAGCAAGATAAGTAAACACGAAGTCATCGACCCGTCTCAACTTGCGAAGGTCACACATACTCCCACTCCGCCTCCAGTCACTGCCTCCGTAGCGAAACGAAGACTGCCACCAGAGGTCGAAGTGACAGTAGTAAATCCAAACAAGAAATTGCGCTCAGACGACTCGGTCGACATGGACATGCAAAATTCTGGTTCAATGGAGGATCGGTACTGCACGATTTGCGACAAGGAATTTACAAAACGGGCGGCGTATCAGCGCCACATGGACGAAGTGCATCAACCGAACTCTGTGTTTTGTCCGGTCTGTGATAAGAGTTTTACAAGGAAGTCCACACTGCTCATTCACATGAAGAAACACTACGAGAGTGGTGAGGGCAGTTCCTCTGCTACAGGTCAAGGGGACGATGATTATTCTTGTGATTTGTGTGGCGCTCAGTATGATAATGATCAGGCGTTGAGGGCGCACCGAGCGCGACACCATGGAGAAGACGAAGAGTCGGCAGAAGAGAGTGATGACGGGAATGTCCCTATAGCTCCTCCCGGCGAATTTACATGCGGGCAATGTGGTGATGGTGTCGCTACTCCTAGGGACCTCATCGCCCACCGCACAATGCACGCTACTCCCACCAAATTCTTCTGTAACATATGCAAAGTGTACTTCGCTCGAGCTCTGGACCTCTCGTCACACACTCGAGCGCGACACGCTGACAACGAAAAGGTATTCTTCCCGTGTGCCATGTGCGACAGGTTTTACATGAACAAGAAGAGTTTACAGCGGCACATCGAGATGGCTCACTGA
Protein Sequence: MNVNYDRVCRLCLSSRGELLPIFPTTSSDDSEPPVLALKIKDCVSVQINENDDLPTNVCRKCMDNVNNWHVFKNVCERTQNKLQSLKDGSQLEEVKIKSEPLSDEAYDDGVAIDGSYPVIENAGFSNKVQPEGPPILASLGLTPRSDKKCVDPRMDWHRVHAILDMVQDNEVIDSLQTKEECDVLQRSDHDSDSEAELKPEIDDNYVDCKSGYICKNKKVISKAPKLSTSVNNARMKDAFKLRKRKLEVRKHCSRPKNAWQLLFTDDLLELIVASTNDNIVTNGKSFSESTSVSEIKTLIGILYLHGIMRPTHQKCTDLWNSECGVPCVRNVMKYERFKFLLQNMSFDKEDDDSIIQFDIMKRMRKVFEIFAMNCRTSHEIENVAVIDEIIVPVYGPCPFRYDIDKKPLKRGIKMVLLVDSSTFYMSNLDVITDPYFGAEEITKKLVQHLAGTGKSIVMDSWFTSASLMDTLKNEYQLYSIAALHPNSDMIPPLFLSQYRKTRSFMSGFIDDEVSLTSYVNAEGKSVNVLTNEPRYYRKGHINHTTVVSVYKKTQSAVEVVDVLMHYYTTMQHTNDWTLTLFFTLLNIASVNAQGAESENNEEDEEEMNEPTQNFPKMPNMPEVSITVMRTTGETLHARQGIHQLASKLCLVCNRSYRYSHNARRHELTSHGFDRYTNKITPKKTLNHLQPKLRPNPFNPKARMMPNPISHKMQFLKKNMPTKIMPMNKVITPQRPIPIKTTSKTQNNLPYPLRIKALKDLQIKKKEPQILKTLLTSKPEVLVSEPEILNSGPESPETLISEPEIASFQVEAILTEPDADAYDDPQQGDEEVDEELQNNQSQNYDTVDMDSDNEIEIARQQSIEQEGEENAEGEENIDHDDDNNEAGQSDNEKDGNDDTAEVQENMEEEDSVDIKPGDHIKDDEDQEDGEHEEVEMNHNEDDEDDDELPITLAPVVEINEGLQSNSFNSQANEEDEELDETVDPNETIEDVEQVKELDPDKTYVTKTQRDFIQKYRDIIQQINTKRCLCCDREHPRRKAVIQHLQKNGHKVPKHTCYNCVITFGHIGALLSHMRSNSCTNLWKIIYNENGITDDLVLEDEPKEVKVAYKDIFNARSYACKLCPAKFQLKQFIMKHVSDTHEDGQSRVPLCCVHCRSRFKEKSLLKKHIRKGDCTVYIACDLCPDTFRNMQDFNDHALAIHAGSFDDNQSKCVDGRPTDCPLCGKKNSSYPNLVKHLKIIHAEEKPHYCQHCDDKYEQAADLNKHIYMEHSDRTLGMPPAEPDMSLVKEEAEEYHYSCTECNAIFETVDAWTDHQVAEHNQVAHHCDQCEKKFLRPSELAEHKNTHLRVKFYPCSVCPNSYSTPQKLSEHVQQSHPGIGAVAAAESEFFCDICIRAFKSRQAYSNHMRIHAKVPTTNRKPAPIKEGFAPQIIGKPIKQYPMVQPGFVSFKPNYNIPNAPYSCDICGKGFMHKKNIWKHKKVLHADILVDRHDSEENTMQASTEEEEFNPDENGAILSTPQFNSFNFANLNNAQQTPPEMTYECELCSKRFPLRTSLWKHKRAKHGIVNPSTSGSNDVSQPSASGEGSSRSSCTICRITFSDKKSYYRHRKNVHKSTVQMCKICGKPLSSTLELYEHLKAAHARELLGYNANQGSSKSQDVPQDMEPDYDNDQESVDPSVDYQARYPCDTCGKQFVGLLALQNHQCINQVSSQPQTFDCEICHKSYTSISALKSHRGWHLRSPDGKAAANNSGLWMPQHKVTSKISKHEVIDPSQLAKVTHTPTPPPVTASVAKRRLPPEVEVTVVNPNKKLRSDDSVDMDMQNSGSMEDRYCTICDKEFTKRAAYQRHMDEVHQPNSVFCPVCDKSFTRKSTLLIHMKKHYESGEGSSSATGQGDDDYSCDLCGAQYDNDQALRAHRARHHGEDEESAEESDDGNVPIAPPGEFTCGQCGDGVATPRDLIAHRTMHATPTKFFCNICKVYFARALDLSSHTRARHADNEKVFFPCAMCDRFYMNKKSLQRHIEMAH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00017541;
90% Identity: iTF_00758469;
80% Identity: -