Ochl020451.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Ornithomya chloropus
Gene Symbol
RHOBTB1
Assembly
GCA_963971445.1
Location
OZ020532.1:27336042-27340696[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 8.4e-08 2.5e-05 24.8 0.1 3 45 256 299 254 324 0.78
2 3 2.7e-07 8e-05 23.2 0.1 49 103 391 444 370 448 0.87
3 3 6.3e-18 1.9e-15 57.4 0.0 10 103 479 571 473 578 0.93

Sequence Information

Coding Sequence
ATGGATAATGAACAGCCGCATCAAGAACTTGTAAAGTGTGTACTGGTAGGTGATACTGCTGTTGGTAAAACACGCCTGATATGTGCCAGAGCATGTAATAAACACGTCTCATTATCACAATTGTTGTCTACACATGTGCCTACTGTTTGGGCTATAGACCAATACCGCATTTATAAAGATgTACTTGAACGTTCCTGGGAAGTAGTTGATGGAGTTAATGTTTCTTTACGGCTGTGGGATACTTTCGGTGATCATGATAAAGATCGTCGTTTCGCTTATGGCCGGTCGGATGTAGTGCTTTTGTGCTTCTCCATCACCAGTCCCATTTCCCTGCGCAATTGCAAAGCCATGTGGTATCCAGAAATAAGACGTTTCTGTCCGGATGTGCCTGTGATATTGGTGGGTTGTAAAAATGATTTGCGTTATATGTACCGAGATGAGACTTATTTATCCTACTTTGGTGAACGAAGTACATTTGTTAGAGCTGCTCTGAAAAGTGACTTGGTAATGCCCGATGAAGCTAGAGCCGTTGCTAAAGAGTTGGGAGTCGCTTATTATGAAACGAGTGTATTCACCTATTTCGGTGTAAATGAAGTCTTCGAAAATGCTATACGTTCAGCCTTAATTGCTAGGCGGCAGCAGCGTTTTTGGATGACCAATTTGAAGAAGGTGCAAAAACCGTTACTGCAAGCACCGTTCCGGCCACCTAAGCCGCCGCCGCCCGAAGTCACCGTTGTGGTGGGCAATTATCGTCAagatatgtataatatgttcCTTGCTCAAAACTATACAGATCTGTTGTTGGTAATTGGTGCCAGCAAATTCTCGGTTCACAAATTTATGCTTGCAACAGCGTCCAATATATTCTGCCGAATTTTGAATACGGAAATTTCGGATATGGGTGGACGCAGTAGTAGCGAATCCAGCATGGTTAGTTCCACCTTTGGCGATGCAACTACTTCGGACTTCAATGATGATACTGAGTGTTTAATACGTCATGAATCCAGAACACAAAGaaTGTGGGAACATTTAAAGCGTAGATCCAGCTATCAGGCCTTGCCTCTCATAGAAACCAAGAGATCCAGTGACCTCTATAAGGAACTGCATCATCCGTTATTTCAAAATATGAGGATTGTACAGTTGGAAATCAGTCGAGGTATTTCGGTTAATCAAACCATAGTTACTATAACTAAGCTCATCACACCGCAGGCTTTACATCAGTgcctaaaatttatttatactggCACGATCGAAAAAGATTTAAATAACATACAGGATACAAAGCAAGCAGCTGACCTGCTCGAACTTACCCAATTGTCACAATTGCTCTCCAAACCGCAAAACGTGTTGGTTGGTTTAAATGATGAAGCAAACCCACACATATGTCTCAGCATTAAGGAGAATATGGAGAAGCATTGTATTGGGGATGGTGGTTTTAATGATATAACCTTTGAATTGGATGATGGGCAAATGAAGGCACATCGTGCCATATTAGTGGCACGTTGTGATGTTATGCGTGCCATGTTAACCGGTGATTTTCGGGAGGCTTATTCCAGTGTGATTGTTTTTCCGGGTGTGACATTGTATACATTCCACAAGCTACTTTGCTATTTATACACTGACGAATTGCCCCCCGTATCAGCGGATAAATGTTTGAATTTATTGGAACTGGCGAATCGTTTGTGCCTGCCTCGTCTCTTAAACTTGATCGAATGCCGTGTCATTGAGGATCTCACATTTATATCGCAAAATGAGACCAATGAGACCGTAGATCATTGCCTTAAGCTTTTAGAACCAGTAAAACTTCACAATGCCCATCAGTTGGCTGAGTGGTGTATGTCCTATTTGTGCGTTAACTACAacataatatgtaaatattcaaTTAAGAGCCTTAGGGCTCTGCATCAGGATAATCAAGAGTATTTGCGAGAGCACCGATGGCCACCGGTATGGTATTTAAAGGATTATGATTACTATCAACGTTGTGTCAACGAAATGAATAAAGAGCTGAAGAATTCAAGGCGCGATTCCAAAAGCGATGAAGATGGCTGCCTGTGCTTTACTGGTGGAAAATCAAAGCAAAGACTAGCACCGAATGGAACAAGCAGTGGCGTGTGTTCAAATGAAAATCAACGGTCGTTACGATTTATTGTAATCTTGCCAGTACTGATCTGTTTCATTTGCACCATTTTGAGTATTTTGATACTTTTTCAAATCTATACGTAA
Protein Sequence
MDNEQPHQELVKCVLVGDTAVGKTRLICARACNKHVSLSQLLSTHVPTVWAIDQYRIYKDVLERSWEVVDGVNVSLRLWDTFGDHDKDRRFAYGRSDVVLLCFSITSPISLRNCKAMWYPEIRRFCPDVPVILVGCKNDLRYMYRDETYLSYFGERSTFVRAALKSDLVMPDEARAVAKELGVAYYETSVFTYFGVNEVFENAIRSALIARRQQRFWMTNLKKVQKPLLQAPFRPPKPPPPEVTVVVGNYRQDMYNMFLAQNYTDLLLVIGASKFSVHKFMLATASNIFCRILNTEISDMGGRSSSESSMVSSTFGDATTSDFNDDTECLIRHESRTQRMWEHLKRRSSYQALPLIETKRSSDLYKELHHPLFQNMRIVQLEISRGISVNQTIVTITKLITPQALHQCLKFIYTGTIEKDLNNIQDTKQAADLLELTQLSQLLSKPQNVLVGLNDEANPHICLSIKENMEKHCIGDGGFNDITFELDDGQMKAHRAILVARCDVMRAMLTGDFREAYSSVIVFPGVTLYTFHKLLCYLYTDELPPVSADKCLNLLELANRLCLPRLLNLIECRVIEDLTFISQNETNETVDHCLKLLEPVKLHNAHQLAEWCMSYLCVNYNIICKYSIKSLRALHQDNQEYLREHRWPPVWYLKDYDYYQRCVNEMNKELKNSRRDSKSDEDGCLCFTGGKSKQRLAPNGTSSGVCSNENQRSLRFIVILPVLICFICTILSILILFQIYT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01300978;
90% Identity
iTF_00384643; iTF_01115084;
80% Identity
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