Basic Information

Gene Symbol
-
Assembly
GCA_951751655.1
Location
OX632364.1:19792165-19795866[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.034 3.9 8.7 0.4 1 20 159 178 159 179 0.96
2 13 0.011 1.2 10.2 4.6 2 23 314 336 314 336 0.91
3 13 4.2e-05 0.0048 17.8 1.4 3 23 392 413 391 413 0.96
4 13 6.1 7e+02 1.6 7.6 3 23 500 521 499 521 0.95
5 13 2.6 3e+02 2.7 0.8 1 23 572 595 572 595 0.92
6 13 0.076 8.7 7.6 0.1 3 23 644 665 642 665 0.94
7 13 0.035 4.1 8.6 0.1 3 23 688 709 686 709 0.92
8 13 0.14 16 6.7 4.4 2 23 773 795 772 795 0.96
9 13 0.011 1.3 10.2 2.4 2 23 809 831 808 831 0.94
10 13 0.00075 0.086 13.9 0.1 2 23 876 898 876 898 0.93
11 13 0.05 5.8 8.1 1.6 1 23 977 999 977 999 0.98
12 13 0.00022 0.026 15.5 1.0 3 23 1017 1038 1016 1038 0.98
13 13 0.04 4.6 8.4 0.5 1 23 1114 1137 1114 1137 0.98

Sequence Information

Coding Sequence
ATGGCGTCCACAGTGGCCCGTGAGCAATTGTCGATGACGATGGATCAGCAGATGAGCGAGATCGACAGCGAGAGTTCGAGCAGTTGCGAGGATCGCGAGGCGCGAAAACGGTTGCGCGAGGATGCGGAAAACACCAGCGGTGGCAGTCCGAAGAAGCGCCGGAAGCAAACAACACCGGTGAGATTTCCAACGTCATTGACGAGCAACAGCGGCGACAGGCCAGAGTCCGAGGCGGATGAAGAAGACGGAGACGAGGACACGGAAGAGAACGAGTTGGAGGACGGCGAAGATGAGGCGGGTGAGGGAGCGACGAGAATTACCAGGGCCGAGGACGAGGAGCCCGACGGGACACTTCCGGAAGGTAAGCCAAGAACGTTATCGCCGCAGGCGTATGCGCAAAGTACGATCGGCCAAACGACAACAGGAACAGGAACGATGGCAACGTTCGCTAAAGACGAGAATCTCAACAGCGAATTTCGCTGTCAATTCTGCGCTCTTACCTTCGACGACAAGGACACGATGTCGCGACATCTAGAATGCGAGCACGCGATCCTTTGCAGCGCGTTGCAAGCGGCCCCGAGTAATTCACCGTTGTCCGATCAAGTTAGGGTTAAGCTAGAGCCGTCGATTCAGATCCTCGAGGATGCCCCCGAGAGTCCCGTGAATCTTTCGGGCCTAGGCATGAAAAGTTTCGCCGCCAATTGGCTGAATTCCCAAGCGCAGGTGCATCAGCAACAGATGCAACTTCAGTCGCAAAATCCCGACGGTTGGACCTCACCCAGTCCCGCAGCTTCCGTTCCTAGTCACCTCCAAGCCCTTACGTTTCCCGGCGGTCTCGCGCAGTATCTCCCTCTACCGGGCTTTTCCCTGGCCGACGCCGGACAACTCGGCCGTCCTCCCGTTGGACCGGCACCCATAAGAATCTTCAATCCGGACGCGTATTGTGATCTTTGCAACAAGGAGTTTTGCAACAAGTACTTTCTCAAGACCCACAAAGCAAACAAGCACGGAATCTACGTGGACGCGCCCTGTCAGAATCCCGGCGACAATGGAATTTCCGGTGGCATGTTCTCCGGCGCGTTCGCGGTTGGTGGTGGGATCAAATCCGAACAGACCCAGAGGCTCGAAGTGCCCACGCCGATGGTCTCCGTGCCCTCGAGCAACGCCGTGGCCTGCGACGTGTGTCAGAAACGCTTCAAGAACGAGGACTCGTTGAGGAAGCACAAGCAAAAGGTTCACAATGGTTCCATCGATAATCAGGAGTCGCATTCGCTTCCCGCAACGAGCAGCAGCGTCGACGAGGAACGCGAACTTTCGCGCAACAGCCCTAGCGCGATGGAGTCACTTTTCAAGCAGGAATTCGGCGTCGAGCAAGAGGACTCGAAGTTCATGCCGGCACCGCGACATCTGTCGCCCCAGTCGAGCCAACAAGCCAGAGACTCGGGCTTCAACGTTGATCGTCTTCGAAGATTGGGCGTCATCAATCCCGAGGCTTTTTGCGAGATATGCTGCAAGGAATACTGCAACAAGTATTTCCTGCGCACCCACAAGATGAAGAGACACGGCATATACGTCCAGGAGAGCGAGAAACCACCCAGCAATCCTGGCAGCGCTGCAACCTGGCATCAGATACAAACGAGTCCGCTGAATCTCATCGTGACCGAAGGCAACGCTGGAAGTTCCTCGGAATCGGGTGATCGCCCGAGCGAAGACTTCGAGTGCAAACCCTGCGGTATCCGCTTTCAGACATTGGGACTTTGTCGCGCGCATCGCGCCAAAATTCACGACACCGACGAGGCCAAATCGCCCAAGCGAGAGTACGAAATGGATCCGACGGAGCAACGAACCGATACCATTTCCGAGGACCTTCAGAAGCTTCAAACGATGATTTTGCAAATCAACGGTCTGGAATCGAGCAAAGCGTTGAACTGCGGCGCGTGCGGCCGTGAGTGCGAGAACATCGGTGCTCTGAGGAGTCACGTGAGGGTGGAACACGGCGGAATGAACGACGAACTTTCCGTCCAATCCAACGAAAATTCACTCCACGGAACGTCGACGTTCTGCACGATTTGCGAGAAGGAATATCAGACGCCGGAAGCGCTTGGCCAACATATCACGGAGGAACATCAGCGTAACCCTAACAATCTCACGTCGAGGCTTTCTCAGCAGGTTATTTCACCAACCGTCACGCTTCAAGGTACCGTTTCCGCAGTGACGACAACGGTAACGGTACCCGCCCCGGCCACGGGCTTGGTGCAAACGCCACCAGCACCGCAGCCCGAAAGAAAGATCACCTCGATGACCCCGACGTCGAGCTACTGCGAGCTATGTCGCAAAGAGCTGTGCAACAAGTACTTCATGAAAACGCACATGCAGAAAATGCACAATATCGAGATAGAGAATGGATCGCAGATAGGTGGCGTGGTATGCAACATATGCAACAAGGAGCTGTGCAGCAAGTACTTTCTGCGCGTGCACAAGCAAAATACTCACGGCATCGTCGACGAGGGTAGCACCGCGTCCAGCAAGCAAGAAACTTACGAATCGTCGAGCAACGAGGACGCGGCGTTGAAGCCCGATCAGCTCGGCGATTTGAGCCATCGTTATTTCACACACTTCACCGAAGTCTGTCCGGTCTGCAGTCGACGATTCAGAAGTATAAAGTGGCTGAAGGCTCATCTCCTCGGGGATCACGGAAAGGCGGGTATCGAGAAGTGGCGGGAGCTCGAGAATCAGTATCAAAGCTCTTCGAGGGCTGGTGTGAGAGGTGCGACGAGCAAAGCGGGTGGGCAAAGTCAGAGCATAAAGATACCCAATGGATTGGAGATGGTGCAGCAGCAGCTGAAGAACAACGATTACGCAGGCCTGGGCAATCAAGTATTGTCGAGTCTCTTCGGTGCGACGACTGACGAACAGCAGGCCAAGAGTTATCGTTGCTCTTATTGCAACTTCACGACTACCGTTTTGCCATTTTTGTTTCTCCACGAGAGATCGCACACGAGCCCCCGGGACAACAGTAATCCAGGGATGGAAAGCGCTTCCCTGTTGTGCCCGATATGCTCGCAGGTTTTCGCTCAACCCGAACTTTTGCATCATCATCTGCTGACGCGTCATCAGTTCTCGGGTCTGTTGTCCCAATTGCCTGGCCCGTTGATGACCAGTCCGAGGCTCGAGGCTGCAAGTTCCGAAAGGAACAATGATAACTACGAGAAGGCCGAGTACGAGAGCAAGGAGGATAATCGCCAGGGCAGTCCTCAAGTTTCTTCGGCAAACATGGAATCGTCTCCGAAGAGCCAAAAGAAGGAGGAAGCCGCGGTGCAGGTCACGCCTCAGGGTGCCTACAAGTGCGCTCAGTGCGGCTTCGCCACGGCAAATCTCAACAGGATCAAAAAACACGTTCGGAAGGATCACAAGACACTCGGTGACGCTACCGAGAGTGTTATCGACGAGTTGAGCAAAACGCTGAGGGACGTTGCGAACAAGCACAAACTACCGGCCAGCTACGCGATGCCTCAGGACATGAATTCAAATCCCGACGCTACGACCATCATGCAACCGTTCTTGATGGAGGAACGGGACGTCGGGCGAATCGGCGATGAAACGAGCCCGGAAAAACGTTTCGCACCTGCCCTTGTCTATTTGCCAGTCAGAGCAAGGATTAACAGTTCCCTCACGACATCGTTCACCCTCAGTCCTGCCTGA
Protein Sequence
MASTVAREQLSMTMDQQMSEIDSESSSSCEDREARKRLREDAENTSGGSPKKRRKQTTPVRFPTSLTSNSGDRPESEADEEDGDEDTEENELEDGEDEAGEGATRITRAEDEEPDGTLPEGKPRTLSPQAYAQSTIGQTTTGTGTMATFAKDENLNSEFRCQFCALTFDDKDTMSRHLECEHAILCSALQAAPSNSPLSDQVRVKLEPSIQILEDAPESPVNLSGLGMKSFAANWLNSQAQVHQQQMQLQSQNPDGWTSPSPAASVPSHLQALTFPGGLAQYLPLPGFSLADAGQLGRPPVGPAPIRIFNPDAYCDLCNKEFCNKYFLKTHKANKHGIYVDAPCQNPGDNGISGGMFSGAFAVGGGIKSEQTQRLEVPTPMVSVPSSNAVACDVCQKRFKNEDSLRKHKQKVHNGSIDNQESHSLPATSSSVDEERELSRNSPSAMESLFKQEFGVEQEDSKFMPAPRHLSPQSSQQARDSGFNVDRLRRLGVINPEAFCEICCKEYCNKYFLRTHKMKRHGIYVQESEKPPSNPGSAATWHQIQTSPLNLIVTEGNAGSSSESGDRPSEDFECKPCGIRFQTLGLCRAHRAKIHDTDEAKSPKREYEMDPTEQRTDTISEDLQKLQTMILQINGLESSKALNCGACGRECENIGALRSHVRVEHGGMNDELSVQSNENSLHGTSTFCTICEKEYQTPEALGQHITEEHQRNPNNLTSRLSQQVISPTVTLQGTVSAVTTTVTVPAPATGLVQTPPAPQPERKITSMTPTSSYCELCRKELCNKYFMKTHMQKMHNIEIENGSQIGGVVCNICNKELCSKYFLRVHKQNTHGIVDEGSTASSKQETYESSSNEDAALKPDQLGDLSHRYFTHFTEVCPVCSRRFRSIKWLKAHLLGDHGKAGIEKWRELENQYQSSSRAGVRGATSKAGGQSQSIKIPNGLEMVQQQLKNNDYAGLGNQVLSSLFGATTDEQQAKSYRCSYCNFTTTVLPFLFLHERSHTSPRDNSNPGMESASLLCPICSQVFAQPELLHHHLLTRHQFSGLLSQLPGPLMTSPRLEAASSERNNDNYEKAEYESKEDNRQGSPQVSSANMESSPKSQKKEEAAVQVTPQGAYKCAQCGFATANLNRIKKHVRKDHKTLGDATESVIDELSKTLRDVANKHKLPASYAMPQDMNSNPDATTIMQPFLMEERDVGRIGDETSPEKRFAPALVYLPVRARINSSLTTSFTLSPA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00263801;
90% Identity
iTF_01101616;
80% Identity
-