Basic Information

Insect: Odynerus spinipes
Gene Symbol: MBD-R2_1
Assembly: GCA_032403825.1
Location: JAIFRP010004408.1:4856382-4864750[-]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 3.5e-17 7.6e-14 50.8 0.2 8 69 544 605 538 613 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	3.5e-17	7.6e-14	50.8	0.2	8	69	544	605	538	613	0.91

Sequence Information

Coding Sequence: ATGAAGCGGCGGCGTATAGCGCGGTCGCGTGTTAAGAGGCTACCACCGCCTGCGGGGGCGATGAGAATGGCGCGCAAATGTTGCGTGCCCAACTGCGAAATCGACGTTCAAGAGGCGCGTACGAAGGGCCTGCCGCTTCATAAATTTCCAAAGGACGCTCTACTCAGAGGCAGGTGGTTGGCCAGCGGCGGTTTCGAGCCGAGCTTCAAGCCGACGCCCGGTCAAGTCGTCTGCCACAGACATTTTAAACGTGCCGACTACGAAGCTGCCAGCAAAACTAACAAGCTAGCGTTGAAGAAAGGCAGCGTGCCTTCGGTTTTTGCAGACTATGACAACCATCCAGATCCAGTAATCATGTCGGTAAAGACCTCTACTTCCTATGCCCAAGAAGATTTGGATTTGATAAATGCAGAGATTTTAAACATGAGACATTCTCCTTTATTATCCGAAGATAGAACGCCAAAGTCTGACAGTTGTGGCGATACTTGTTATTCTAGACCAGAATCGTCTGCGGATTCAGTTAATTTATTGGAGACCACAGATTCGATGGAGCAGGGGTGCAGATTGTCGGTGGAAAAAAATTCTAGGAATATGAAAGAGGAAATGCTTGAAGATTcggaaataaaagtaaatactaTGGCGATACAATTGGGTATAGTTGAACCTGAAATAGCTATGCAGCATGTGCCCAAAGATTTGATTCTCAAAAATGAGTTAAATGGATTTAAAGAGGTAGACGAGAAAGATTTTGACAAAGCTGATGacttaaaaacaaaagtgCTAAGTCGCGATAGTTTAAAATTCTTCCCTGGTGCCAAATTGGAAGCAAAGGACTTCAATGAAAAGTGGTATTCTGCTAAAGTAGTGGAAACGGATTGGGTGGAAAGAGAAGTACTGATACATTTTGATAAGTGGAGTGCAAGATTCGATGAGTGGATACCGATGGATAGTTCGAGGCTACGAGTATCGCAAACAGAGCCAAACGAGCAAACTTGGGTGCTGCCATCTCCGGAGACGAGCATGAGAGAGTTCTCAGTGGGAGAAAGGATCCTAGCTACGTGGGCGGACGGCAGAAAATACCCTGCGAAAGTAAACGCCGTCTTAGGGAATGACAGGTATGATGTGCTCTTTGACGATGGATACGCAAAGATTGTCAGGTCCTCGAAGATGACTAAAATTGCCACCCCGCCCGAAACGCAGCAACCGGTTCAGGAAGAAGGCTATATAGGAAgtaaacaagaaagaagagacaagaagaggaagcatACTGTCATGGAACTTTTTCATACACACTCTAGGAAGCGTTCAAAAAATGACATGGATAAAatagcgaagaaagaagaacccGTCGCTCGTGACAATGCAGATAGTTTTTCAGAACCAAAGATCGACTTGGATGGTACCTTATTTGGACCTTGTTACGATCCTGGAACAGATTTATTAAAAGGATTTAATGCAAATGTGCCAAAAACAAAGCCATTGgcaaaaaaaacgaagaaagaaacgcatAAATCTGATGCGGAACAGGAAGAATACGTGGGTCCAGCATGGATTGACGGAGAACCTCAGGGAATTGAATCTTATATCGTAGATGGAAATGATGGGCCACGCCGTTCTATTATTGTACCTGATAAAAGATTACCTCCAGGCTGGCAAAAACATTTCACGCAAAGAAAAGCTGGTACATCTGCAGGAAAATGggatgttttatttatacaCAAATCTAGTGggaaaaaatttcgatcgagaaatgaTATCAGAGCATTTATGGAAAATCAAGGCCAATTTGACTTTGACCCTGATAAATTTGACTTCTGCATtcatcgtaagaaaaaaaatcatggaCAAAAGTTAAAACAAGATATTCCTACACCAGAAGTACCAAAGAAGATTAAGACATTGTTGCCTAAAGTAAAAACACCAGCTTCTACTGAAAGTACACCGCTCGCGCCAGTAAATATACCAGTTACCACACCAGTGATGTCTGCCAATTCTACTCCTGTAACACCTATAACTAATGGCGCTGTTTTCATCGGTGGCCTTCGAGTGGAAATGGAAGATAGTGCTTACAAGTGTCCTAAGCAAGGatgtaataaaacatttcgaaaagaaaatcttttgcAAATGCACATAAAGCATTATCATCCAGAATATTCCAAATTTTTGGGATCTACACCAAATGTTGCAGATTTGGCATATGCAAGAACGATCGGAGAGTCTATCGATGATATTATTCCAAAGAAAACGACTCCTCTATTGGAAAAAATGACCAAGTTTGGGAAAAAGAAGACTTCTCAAGACAGGTCACCTTTACCTGGGTCGCAATCAGGATTAAATTTTGTGCAGCCTAGCTCTCCATCGGTATCATTACCAATGCTCGATGAACGTGAAGATGAAGTCGATCAACTAGACAAAATAAATGAATCGCATAAAGATGATATTAAGATGGAAACTATGTCACCTATTTCGAGTCATAGTATGGAAGTGGATGAGgatatagaaaaaaggagagagaattcgTGTGCAATGTCACCTGGGACGCTGTTCGATATGAAAataagagaggagaaaacagagaaagttggaattaaaacattattgcCCGTTCGGCCACCTACAACGTCCGAGGTACAAAGAGTCGATAGATCAAAGTCCTTGGACGATTCTGTGCAcgttgaaagaggaaaaggtcAACGGAAGCGTCAATTGTCAGAATACAGTTCCGATTTACCATCTAAAGGGAAAAGGCGACACgCTATGCAAGAAGTCGTAGATGATTATGGAGATATAGACGACAGTGCTGTAGATACGGAAGGTCCTACCACTTTGATGTACAGATACAGTCGCAGAAAATCCGATTCTAAGAGCGATGAAAATAGTCAAAATAGTCAACTTAATGATTCTCGCCTTGAGAAAGGTGACCCCTTCAAAGGGGATTCTGCAAAAAGAGATAATAGTAATGACGCGGAAGAAAACGAAGGTGTTATGATGATGATCAACGGAGAAATGGTAAAAGTGGAACAACTTCGTCgtgaagaaataattaattgtaccTGTGGGTTTATGGAAGAAGACGGTTTAATGATACAGTGTGACCTCTGCTTGTGTTGGCAGCATGGTCATTGTAATGCcattgaaaaagagaaggatgtTCCTGAAAAATACGTTTGTTATATTTGTCGACACCCGTATCGAGAGAGGCCTTCCAGAAAGTACTATCACGATCAAGATTGGATTAAGGAAGGCAAACTGCCAAGTTTACCTAGTCGGACGAAGAACCAGGACGCGATTAATAGAAGAACCGCAATATTAAAGCGATCGTATGATTTAGTCGCGGCTCTCCTACAAATCCAACAAATTCTTCATAGCTTGAGAGTGAAAATTAATGTAGCTCAGAAAAAGGATCATCCAAAATTGTATCTGTGGGCTAAGAACTGGGAAAAAATGGATGTACCCAAACCGGATACGGAACCTGTTCCGGTGATGGAGGTAACAAAAACGCCCGTGGATTCCGTCGATACAAGCTCCGAAACATCTAGACGGACAGACATcaaaatagaaacgagaacgTCGCTGAAGGATGATCATGACGACAAATCAATAGCCTCGGATTcagaattaatgaaaattctgGAAGAAGATAGCTCGAATTCAGACGAGTCTAAAGTAATGTGTAAGAAGGAGGATACGGTTAATTCAAACGACGGTCACATATTGTTAGACGCGCTAACGAGAAACGGAAGTCCCgtcgaaaaacaaaaattgaagcTTGAAAATGCAACGGAAAATATGAATACAGCCGCTTTGGAAGATAACAAATCGACGTGCGGATTATTTATGGACACTATACATGATGAAACGAATGCACCTGAAATTGGACAGGAATTGTCAACTCCGTTGCAACCATTTATTCCGGAACCCGAAGCACCGATTGATTCGGCAGAATGTCGAATGAGATTGCTGGAACATATTGAACATTTTCAAAGTCACATAGATTCGAGATTAATATCTATAGAAGCCCAAGTTTGTGCTTTGGAGGCTATGGATCCTGACGAGATAATACCAAGTCCGGACGTTCAACCTCGGACGAAACAAACCGTGAAAATGTTACTTCGGGATTTAAATACAGTCCGTAAATTGGCTGCTTTATGTTAA
Protein Sequence: MKRRRIARSRVKRLPPPAGAMRMARKCCVPNCEIDVQEARTKGLPLHKFPKDALLRGRWLASGGFEPSFKPTPGQVVCHRHFKRADYEAASKTNKLALKKGSVPSVFADYDNHPDPVIMSVKTSTSYAQEDLDLINAEILNMRHSPLLSEDRTPKSDSCGDTCYSRPESSADSVNLLETTDSMEQGCRLSVEKNSRNMKEEMLEDSEIKVNTMAIQLGIVEPEIAMQHVPKDLILKNELNGFKEVDEKDFDKADDLKTKVLSRDSLKFFPGAKLEAKDFNEKWYSAKVVETDWVEREVLIHFDKWSARFDEWIPMDSSRLRVSQTEPNEQTWVLPSPETSMREFSVGERILATWADGRKYPAKVNAVLGNDRYDVLFDDGYAKIVRSSKMTKIATPPETQQPVQEEGYIGSKQERRDKKRKHTVMELFHTHSRKRSKNDMDKIAKKEEPVARDNADSFSEPKIDLDGTLFGPCYDPGTDLLKGFNANVPKTKPLAKKTKKETHKSDAEQEEYVGPAWIDGEPQGIESYIVDGNDGPRRSIIVPDKRLPPGWQKHFTQRKAGTSAGKWDVLFIHKSSGKKFRSRNDIRAFMENQGQFDFDPDKFDFCIHRKKKNHGQKLKQDIPTPEVPKKIKTLLPKVKTPASTESTPLAPVNIPVTTPVMSANSTPVTPITNGAVFIGGLRVEMEDSAYKCPKQGCNKTFRKENLLQMHIKHYHPEYSKFLGSTPNVADLAYARTIGESIDDIIPKKTTPLLEKMTKFGKKKTSQDRSPLPGSQSGLNFVQPSSPSVSLPMLDEREDEVDQLDKINESHKDDIKMETMSPISSHSMEVDEDIEKRRENSCAMSPGTLFDMKIREEKTEKVGIKTLLPVRPPTTSEVQRVDRSKSLDDSVHVERGKGQRKRQLSEYSSDLPSKGKRRHAMQEVVDDYGDIDDSAVDTEGPTTLMYRYSRRKSDSKSDENSQNSQLNDSRLEKGDPFKGDSAKRDNSNDAEENEGVMMMINGEMVKVEQLRREEIINCTCGFMEEDGLMIQCDLCLCWQHGHCNAIEKEKDVPEKYVCYICRHPYRERPSRKYYHDQDWIKEGKLPSLPSRTKNQDAINRRTAILKRSYDLVAALLQIQQILHSLRVKINVAQKKDHPKLYLWAKNWEKMDVPKPDTEPVPVMEVTKTPVDSVDTSSETSRRTDIKIETRTSLKDDHDDKSIASDSELMKILEEDSSNSDESKVMCKKEDTVNSNDGHILLDALTRNGSPVEKQKLKLENATENMNTAALEDNKSTCGLFMDTIHDETNAPEIGQELSTPLQPFIPEPEAPIDSAECRMRLLEHIEHFQSHIDSRLISIEAQVCALEAMDPDEIIPSPDVQPRTKQTVKMLLRDLNTVRKLAALC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01232400;
90% Identity: iTF_01090042;
80% Identity: iTF_01090042;