Ople012126.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Ochropleura plecta
Gene Symbol
Rfx2
Assembly
GCA_905475445.1
Location
FR997726.1:19636502-19659894[+]

Transcription Factor Domain

TF Family
RFX
Domain
RFX domain
PFAM
PF02257
TF Group
Basic Domians group
Description
RFX is a regulatory factor which binds to the X box of MHC class II genes and is essential for their expression. The DNA-binding domain of RFX is the central domain of the protein and binds ssDNA as either a monomer or homodimer [1]. It recognize X-boxes (DNA of the sequence 5'-GTNRCC(0-3N)RGYAAC-3', where N is any nucleotide, R is a purine and Y is a pyrimidine) using a highly conserved 76-residue DNA-binding domain (DBD) [2].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 1.5e-37 3.4e-33 115.4 0.0 3 78 228 303 226 304 0.97

Sequence Information

Coding Sequence
ATGTCTGAGATGGGCTTTGAGAATGTGTTCTATTTAGAGAACTTTGAGTGCGCCGGCGACGAGGTGCTGGTGGAGTCGTCGCCGCCTGCTTCACCGGACATGGCAGCGAGGCTCGCGGCTCCTGCACAGGGTGGCGCGGGCGGCGGTGCCTCGCCGAGCGCGGTGCGTGATCTCATCGTAATACCGGAAATACCCGACTCCATGCATTTGCAGCACGCTATGCAACAGGTAACGAGTACGGTGGTGGAAGTGAACGGCGACAGTTCCGGCCAGTCCAGTCCCACGGCCGAGGGGCAGCACACTTACATCACTGTAGCGAGCGAGTTGCAAGGCGCATGGGCTCAACCTGGCTCCCAAGTGAAGATTGAGGAACAAAGTGACCAAGAAAGCGAGGGCGGCAATGGAGTCAACTACCACGTGCAGTATGTTACGGAGCCGCAAGAGATCTACACACAAGGTCACCCGACGCATATGGATTCGTTGCGCTCCTACCCAGTGTATGGGGTGACGACGGTAGGGAATGGCCCAAGTGCGGAAGGCACGTCCGCCGACAACGGATGGGGTGGAGCTTCTTCCGCTGAATACACGGCTTATGGCGTCGTGGTGGCTGGCGACGAGGCCGAAGCCCCGGCGTCCCCGGCCACCCCGGCCGGAGCGCCCGCCCCGCCGCGCATGCCGCCCGCCACAGTGCAGTGGCTACTCGACCACTACGAGACCGCTGAGGGCGTGTCACTCCCTCGCTCAACTCTCTACGCGCATTACCTCCGCCACTGCGGGACCCACCGACTGGAACCAGTCAATGCTGCATCCTTCGGCAAGCTCATCCGGTCCGTCTTCATAGGCCTTCGTACTCGCAGGCTTGGGACTAGGGGGAACTCCAAGTATCACTACTACGGGATCAGGGCGAAGCCCGGGGTCGAACATGATCACAGCGAGAGCGATGTCAATGATCAACAGGAGAATAATGATGATAAGACCGATGTGTTGGATCTGCAGGACGGGCGCTCCCGCTCCCCCCGGTCCCGCGAGCCGGCCAGCAGCCCCGGGCTGGCCCACCGGCAGTACCTGGGCTCCGTGTCGCCGCCCGAGCCTCCGCCGCTAGTGATCCACCCGCTGCCCGACGATGTGCCGCCCGAGGCACTTAATGCGCTGAGGAGACACCATCGGGAGCACGGCGCGGAGTTCCTGTCGGCGGTGGCGGCGCTGGACTCGGGCGGCGTGGAGCGCGCGCGCCGCGCCTTCTGGAGGCGCCCCGCCGGCGCGCTGTGCCGCCGCGTGCTGGCGCGGCTGGCGGCGCGGCGCGACGTGGGCGAGTGGCTGCGCGCGGCCGAGCTGCAGCTGTACCAGCGCGCCGTCGAGCTGCTGCTGCCCGACGTGCTGCGGCCCATACCGCCGCAGCTCACGCAGGCGATCCGCAACTTCGCGAAGAGCCTGGAGGGCGCGCTGGCGGCGGGCGCGGACTCGGCCCCGGCGgccgcggcgcgcgcgcaggcgtcggcggcggcggcgctggCGGCGGCGCTGCGCCGGTACACGTCGCTCAACCACCTGGCGCAGGCCGCGCGGGCCGTGCTCAACAACCATCATCAGATACATCAGCTTGGCAATAATCTTAACCTATCATATACGTACTAG
Protein Sequence
MSEMGFENVFYLENFECAGDEVLVESSPPASPDMAARLAAPAQGGAGGGASPSAVRDLIVIPEIPDSMHLQHAMQQVTSTVVEVNGDSSGQSSPTAEGQHTYITVASELQGAWAQPGSQVKIEEQSDQESEGGNGVNYHVQYVTEPQEIYTQGHPTHMDSLRSYPVYGVTTVGNGPSAEGTSADNGWGGASSAEYTAYGVVVAGDEAEAPASPATPAGAPAPPRMPPATVQWLLDHYETAEGVSLPRSTLYAHYLRHCGTHRLEPVNAASFGKLIRSVFIGLRTRRLGTRGNSKYHYYGIRAKPGVEHDHSESDVNDQQENNDDKTDVLDLQDGRSRSPRSREPASSPGLAHRQYLGSVSPPEPPPLVIHPLPDDVPPEALNALRRHHREHGAEFLSAVAALDSGGVERARRAFWRRPAGALCRRVLARLAARRDVGEWLRAAELQLYQRAVELLLPDVLRPIPPQLTQAIRNFAKSLEGALAAGADSAPAAAARAQASAAAALAAALRRYTSLNHLAQAARAVLNNHHQIHQLGNNLNLSYTY*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00123965; iTF_00887942; iTF_00444843; iTF_00685166; iTF_00071155; iTF_00172465; iTF_00425106; iTF_00711547; iTF_01062491; iTF_01525661; iTF_00446847;
90% Identity
iTF_00887942;
80% Identity
-