Basic Information

Insect: Ochropleura leucogaster
Gene Symbol: Zfa
Assembly: GCA_958449745.1
Location: OY288211.1:6439380-6447812[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 23 0.0071 0.57 11.5 1.1 3 23 582 603 581 603 0.96

2 23 0.23 18 6.7 0.3 1 22 988 1009 988 1009 0.95

3 23 8.3 6.6e+02 1.8 0.4 1 22 1051 1072 1051 1074 0.82

4 23 0.018 1.4 10.2 4.8 2 22 1084 1104 1083 1104 0.93

5 23 2.4 1.9e+02 3.5 0.0 3 23 1113 1134 1111 1134 0.89

6 23 0.019 1.5 10.1 0.2 3 23 1155 1176 1153 1176 0.96

7 23 0.0041 0.33 12.2 3.5 1 23 1182 1205 1182 1205 0.95

8 23 0.14 11 7.4 0.0 1 23 1231 1254 1231 1254 0.90

9 23 0.021 1.7 10.0 3.4 1 23 1259 1281 1259 1281 0.97

10 23 0.0095 0.76 11.1 0.2 1 23 1287 1310 1287 1310 0.95

11 23 0.0044 0.35 12.1 0.8 1 23 1323 1345 1323 1345 0.97

12 23 0.0002 0.016 16.4 1.8 1 23 1395 1418 1395 1418 0.97

13 23 0.0012 0.1 13.8 1.4 1 23 1478 1501 1478 1501 0.96

14 23 0.0026 0.21 12.8 2.1 2 23 1528 1550 1527 1550 0.95

15 23 0.044 3.5 9.0 0.1 2 23 1556 1578 1555 1578 0.94

16 23 0.011 0.87 10.9 0.2 1 21 1622 1642 1622 1643 0.95

17 23 0.00046 0.037 15.2 1.0 1 23 1653 1675 1653 1675 0.93

18 23 0.00012 0.0099 17.0 0.3 2 23 1768 1790 1768 1790 0.93

19 23 4.4e-07 3.5e-05 24.7 1.4 3 23 1797 1817 1796 1817 0.98

20 23 0.024 1.9 9.8 0.3 1 23 1835 1857 1835 1858 0.95

21 23 0.2 16 6.9 0.0 1 23 1881 1903 1881 1903 0.97

22 23 0.03 2.4 9.5 0.6 1 23 1909 1932 1909 1932 0.95

23 23 0.00028 0.022 15.9 0.4 1 23 1940 1963 1940 1963 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	23	0.0071	0.57	11.5	1.1	3	23	582	603	581	603	0.96
2	23	0.23	18	6.7	0.3	1	22	988	1009	988	1009	0.95
3	23	8.3	6.6e+02	1.8	0.4	1	22	1051	1072	1051	1074	0.82
4	23	0.018	1.4	10.2	4.8	2	22	1084	1104	1083	1104	0.93
5	23	2.4	1.9e+02	3.5	0.0	3	23	1113	1134	1111	1134	0.89
6	23	0.019	1.5	10.1	0.2	3	23	1155	1176	1153	1176	0.96
7	23	0.0041	0.33	12.2	3.5	1	23	1182	1205	1182	1205	0.95
8	23	0.14	11	7.4	0.0	1	23	1231	1254	1231	1254	0.90
9	23	0.021	1.7	10.0	3.4	1	23	1259	1281	1259	1281	0.97
10	23	0.0095	0.76	11.1	0.2	1	23	1287	1310	1287	1310	0.95
11	23	0.0044	0.35	12.1	0.8	1	23	1323	1345	1323	1345	0.97
12	23	0.0002	0.016	16.4	1.8	1	23	1395	1418	1395	1418	0.97
13	23	0.0012	0.1	13.8	1.4	1	23	1478	1501	1478	1501	0.96
14	23	0.0026	0.21	12.8	2.1	2	23	1528	1550	1527	1550	0.95
15	23	0.044	3.5	9.0	0.1	2	23	1556	1578	1555	1578	0.94
16	23	0.011	0.87	10.9	0.2	1	21	1622	1642	1622	1643	0.95
17	23	0.00046	0.037	15.2	1.0	1	23	1653	1675	1653	1675	0.93
18	23	0.00012	0.0099	17.0	0.3	2	23	1768	1790	1768	1790	0.93
19	23	4.4e-07	3.5e-05	24.7	1.4	3	23	1797	1817	1796	1817	0.98
20	23	0.024	1.9	9.8	0.3	1	23	1835	1857	1835	1858	0.95
21	23	0.2	16	6.9	0.0	1	23	1881	1903	1881	1903	0.97
22	23	0.03	2.4	9.5	0.6	1	23	1909	1932	1909	1932	0.95
23	23	0.00028	0.022	15.9	0.4	1	23	1940	1963	1940	1963	0.96

Sequence Information

Coding Sequence: ATGAATGTGAACTATGATCGTGTTTGTAGACTGTGCTTGTCATCTCGAGGCGAATTACTGCCGATTTTTCCTACCACCAGTTCGGATGGCTCAGAACCTCCCGTCCTCGCTTTGAAAATCAAGGAATGTGTGTCCGTACAGATAAACGAAAATGACGACCTGCCCACCAATGTCTGCAGGAAATGCATGGACAATGTCAATAACTggcatgtttttaaaaatgtatgtgaAAGGACACAAAACAAACTACTGTCTCTAAAAGATGGCAACCAACTAGAAGAGgtaaaaataaaaagtgaaccACTGTCTGATGAGGCTTATGATGATGGAGTGGTCATTGATGGGTCATATCCTGTCATTGAGaatgCTGGCTATTCAAACAAAGTGCAACCTGAAGGTCCCCCAATCTTGGCTTCATTGGGGCTCACACCAAGAAGTGATAAGAAATGTGTGGACCCGCGAATGGATTGGCACCGGGTCCATGCAATTTTGGACATGGTTCAAGACAATGAGGTGATTGACTCTCTGCAGACAAGGGAAGAGTGTGATGTTTTGCAGTATTCAGACCATGACTCGGATACTGAAGCTGAACTCCTAACAGAAATTGATGATGGTTATGTTAATAGCAAATCTGGATATatatgcaaaaataaacaagttatgTCAAAAGTTCCAAAACTTTCAACTTCTGTAAATAATGCAAGAGTGAAAGAAGCTTTCAAACTAAGGAAGCGTAAATCAGAAGTTCGTAAACATTGTTCACGACCTAAAAATGCGTGGCAGTTGTTATTCACTGATGACCTACTAGAGTTGATTGTCGCTTCCACTAATGACAATATTGTGACCAATGGGAAAAGTTTCACGGAGTCAACGAGCGTCAGCGAAATTAAAACGCTTATCGGTATTCTGTATCTGCACGGTATAATGCGGCCGACGCATCAGAAACTAAGTGACCTTTGGAACAGTGAATGTGGTGTACCTTGTGTCAGAAATATCATGAAATACGAAAGGTTCAAATTCCTGCTACAAAACATGAGCTTCGATAAAGAGGACGACAACAGCATTATACAGTTTGACATAATGAAGCGTATGCGTAAAGTATTCGAAATCTTCGCCATGAATTGCAGAACAGCTCACGAGATAGAAAATGTCGCGGTTATTGATGAGATCATCGTGCCAGTTTACGGCCCTTGCCCATTTCGATACGATATTGATAAGAAGCCGCTGAAGCGGGGTTTAAAGATGGTATTGCTAGTTGATTCATCTACATTCTACATGAGTAATTTAGACGTCATCACTGATCCATACTTTGGCGCCGAGGAGATAACGAAGAAGTTGGTTCAGCATTTGGCGGGAACTGGCAGATCTATTGTTATGGACAGTTGGTTCACTTCTTCTTCATTGATGGATATCCTTAAAAATGAGTACCAGTTGTATTCTATTGCAGCCTTGAACCCAAAGAGTGATATGATTCCACCACTGTTCCTATCTCAGTACAGGAAATGTCGAACATTCATGTCTGGATTTATTGATCATGAAGTATCCATGACATCGTATGTCAACACTGAGGGGAAATCCGGCGCGGAGAGTGAAAACAATGAAGAAGACGAGGAAGAAATGAATGAACCCGCTCAAAATTTCCCAAAAATGCCTCACATGCCCGAGGTATCTATCACGGTCATGAGGACTACTGGTGAGACCCTGCACGCTCGCCAAGGTATTCACCAACTCGCCTCCAAACTGTGCCTCGTTTGCGGCCGCTCGTACAGGTACTCTCACAACGCACGCAGACATGAACTTACCGCTCACAGCTTCGACagatatacaaacaaaattaccCCTAAAAAAACCCTCAATCATCTACAACCCAAACTGAGACCAAACCCATTCAACCCCAAAGCACGGATGATGCCGAATCCTATTAGTCATAAGATGCAGTTCATGAACAAGAACATGCCCACGAAAATAATGCCCATAAACAAAGTTATAACGCCACAGAAACCCATTCCAATAAAGACGTCGTCAAAGACACAAAATAATTTGCCTTATCCTCTACGCATTAAAGCactcaaagatttacaaattaaGAAAAAGGAGCCTCAGATTCTAAAGACTTTGTTGACTTCTAAACCAGAAGTACTGGTCTCAGAACCGGAAATTCTAAATTCTGGGCCTGAAAGTCCAGAAACATTGATATCTGAGCCTGAAATTGCATCTTTTCAAGTTGAAGCTATCCTTACGGAACCGGATGCCGATGCATACGATGATCCACAGCAAGGTGACGAAGAAATCGATGAAGAAATGCAgaacaatcaaaatcaaaactatGACACTGTCGATATGGACTCTGAGAACGAAATAGAGATTGCTCGTCAGCAAAGCATTGAACACGATGGCGAGGAAAATGTTGATGGagacgacaatatggaccatgATGACGACAATAACATGGAAGGCGGTCAGAGTGATAACGAGAAAGATGCCAATGATGATACAGCTGATAGCCAAGAGAACATAGAAGAAGAAGATAGTGTTGATATCAAACCTGAAGATCAAATGAAGGACGATGATGGCCAAGAGGAAGGAGAACACGAAGAAGTAGAAATTAATCATAATGAAAACGAGGAAGAAGACGACGATGACCTGCCGATGTCTCTAGCTCCCGTCGTCGAAATAAGTGAGGGGTTGCAAGGCGACTCGTTCAACAGCGAAGTCGTTGAGGAAGAAGAGGAGCTCGACGAAACTGTTGATCCCAATGATACGATCGAAGAGGAAGAGCAGGTTAAGGAACTTGACCCTGACAAAACATATGTTACTAAAACCCAAAGAGACTTCATCCAAAAATACCGCGATATCATTCAGCAAATCAACACGAAACGTTGTTTATGCTGTGATCGAGAACATCCGCGCAGAAAAGCTGTTATACAACACTTGCAGAAAAACGGTCACAAGGTACCAAAACACACATGCTATAATTGTGTCATCACGTTCGGTCATATTGGCGCACTACTCAGCCATATGAGGTCGAATTCTTGTACCAATTTGTGGAAGattatttacaatgaaaatGGCATTACTGACGACTTGGTTCTCGAAGATGAGCCGAAAGAGGTCAAGGTTGCTTACAAAGATATCTTCAATGCCAGGTCGTACGCTTGCAAACTCTGCCCTGCAAAATTCCAACTGAAACAGTTCATAATGAAACATGTTTTGGATACCCATGAGGATGGACAGTCAAGGGTGCCACTGTGTTGCGTCCACTGCCGTTCTAGATTCAAAGATAAGAGTTTACTAAAGAAACACATTCGTAAAGGCGATTGTACAGTTTATATTGCTTGCGATTTGTGCTCAGAAAAGTTCGGTAACATGCAGGACTTCAACGACCATGCGCTAGCCATCCACGCTGGCAGTTTCGATCAGTCGGATAATCAGAGCAAATGTGTTGACGGTCGACCGACAGACTGTCCTCTGTGTGGAAAGAAAAACAGTAGCTATCCGAATTTAGTAAAACATTTGAAGATTATACATGCAGAGGAAAAACCTCACTACTGCCAGCATTGCGACTCGAAATTCGAACAAGCTACTGATCTGAACAAACACATTTACATGGAGCATTCTGACAGGACATTAGGCATGACGCCTGCTGAACCCGATATGTCCATTGTGAAGGAAGAAGCAGAGGAGTATCACTACTCCTGTACAGAATGTAATGCGATATTCGAAACTGTTGATGCGTGGACTGATCACCAAGTCGCCGAACATAACCAGGTGGCCCACCACTGTGACCAGTGTGAGAAGAAATTCCTTCGTCCTTCAGAGCTGGCAGAACACAAGAACACTCACTTGAGGGTTAAGTTTTATCCTTGCAGTGTATGTCCTAACTCTTACAGCACACCACAGAAACTGTCTGAGCATGTGCAACAGTCACATCCTGGAATAGGAGCGGTCGCGGCAGCAGAGTCTGAATTCTTCTGCGACATCTGCATCAGAGCTTTTAAGAGTCGCCAAGCTTACTCAAATCATATGCGTATTCATGCTAAAGTACCTACCACTAACAGGAAACCGACTCCAACCAAAGATGGATTCACGCCTCAAATAATTGGGAAACCCATCAAGCAGTATCCTATGGTTCAACCGGGTTTTGTATCATTTAAACCTAATTACAACATCCCTAACGCTCCTTATTCTTGTGACATCTGTGGTAAAGGATTCatgcataagaaaaatatatggaAACACAAGAAAGTGTTGCATGCTGATATTTTAGTCGATAGACATGATAGTGAAGAGAACACTATGCAAGCTTCTACAGAAGAGGAGGAATTCAATCCTGATGAGAATGGTGCCATTCTTTCAACGCCgcaatttaatagttttaactTTTCGAACTTCCCGAACAATACTCAACAATCAACACCAGAAACAATGCCATATTCGTGTGAGTTATGCAGCAAACGGTTCCCACTTAAGACCAGTTTATGGAAACACAAGCGCGCTAAACACGGAATTGTGAACCCTAGCACTAGTGGTAATAACGAAACATCCACGCCGTCCGCTAGCGGGGAAAGCAGTAGTCGATCTAGCTGCACTATATGCAGAATCACATTTTCAGATAAGAAATCTTACTATCGCCATCGAAAGAATGTCCACAAATCTACAGTTCAAATGTGCAAAATATGTGGCAAACCGCTAAGTTCAACTTTGGAATTATACGAACACTTGAAAGCTGCTCATGCAAGGGAGTTACTGGGTTATAATGCTAATCAAGGGTCCAGTAAATCACAAGATATGGCACAAGAGATAGAACCCGATTATGAAAATGATCAGGAGTCTCTCGACCCCAGCGTTGATTACCAAGCGCGGTACCCCTGCGATACTTGTGGTAAACAATTTGTTGGTTTGCTAGCTTTGCAAAACCACCAGTGCATCAATCAGATATCATCACAGCCACAGACATTTGACTGTGAGATTTGCCACAAGAGTTACACTTCAATATCTGCGCTAAAAAGCCATCGTGGGTGGCATTTACGTTCGCCCGATGGAAAAGCTGCCGCCAACAATTCTGGCCTTTGGATGCCTCAGCACAAAGTTACAAGCAAGATAAGCAAACATGAGGTTGTGGACGCGTCACAACTGGCTAAGGTCACACACACCCCCACTTCCCCACCTGTCTCTGCTACGGCAGCAAAAAGAAGACTACCACCAGAGGTCGAAGTGACAGTCGTAAATCCCAACAAGAAACTGCGTTCAGACGACTCGGTCGACTTGGATATGCAAAATTCTGGTACCATCGAGGACAGGTATTGTACGATTTGCGATAAGGAATTTACAAAACGAGCGGCGTATCAGCGTCACATGGACGAGGTACATCAACCGAACTCTGTGTTTTGCCCGGTCTGTGATAAGAGTTTTACAAGGAAATCCACATTGCTCATTCACATGAAGAAACATTACGAAAGTGGTGAGGGTAGTTCCTCCGCTACAGGTCAAGGGGACGATGATTACTCGTGTGATTTGTGTGGAGCTCAGTACGACAACGACCAGGCGTTGAGAGCGCACCGAGCGCGGCACCACGGAGAAGATGAAGAGTCGGCTGAAGAGAGTGATGACGGAAATGTTCCTATTGCTCCTCCCGGTGAATTCACATGTGCGCAATGTGGCGATGGCGTCGCTACTCCCAGGGACCTCATCGCCCATCGCACAATGCACGCTACTCCCACCAAATTCTTCTGTAATATATGCAAAGTGTACTTCGCTCGGGCGCTCGACCTCTCCTCGCACACTCGGGCGCGACACGCTGACAACGAAAAGGTATTCTTCCCGTGTGCCATGTGCGACAGGTTTTACATGAACAAGAAGAGCTTACAGCGGCACATCGAGATGGCTCACTGA
Protein Sequence: MNVNYDRVCRLCLSSRGELLPIFPTTSSDGSEPPVLALKIKECVSVQINENDDLPTNVCRKCMDNVNNWHVFKNVCERTQNKLLSLKDGNQLEEVKIKSEPLSDEAYDDGVVIDGSYPVIENAGYSNKVQPEGPPILASLGLTPRSDKKCVDPRMDWHRVHAILDMVQDNEVIDSLQTREECDVLQYSDHDSDTEAELLTEIDDGYVNSKSGYICKNKQVMSKVPKLSTSVNNARVKEAFKLRKRKSEVRKHCSRPKNAWQLLFTDDLLELIVASTNDNIVTNGKSFTESTSVSEIKTLIGILYLHGIMRPTHQKLSDLWNSECGVPCVRNIMKYERFKFLLQNMSFDKEDDNSIIQFDIMKRMRKVFEIFAMNCRTAHEIENVAVIDEIIVPVYGPCPFRYDIDKKPLKRGLKMVLLVDSSTFYMSNLDVITDPYFGAEEITKKLVQHLAGTGRSIVMDSWFTSSSLMDILKNEYQLYSIAALNPKSDMIPPLFLSQYRKCRTFMSGFIDHEVSMTSYVNTEGKSGAESENNEEDEEEMNEPAQNFPKMPHMPEVSITVMRTTGETLHARQGIHQLASKLCLVCGRSYRYSHNARRHELTAHSFDRYTNKITPKKTLNHLQPKLRPNPFNPKARMMPNPISHKMQFMNKNMPTKIMPINKVITPQKPIPIKTSSKTQNNLPYPLRIKALKDLQIKKKEPQILKTLLTSKPEVLVSEPEILNSGPESPETLISEPEIASFQVEAILTEPDADAYDDPQQGDEEIDEEMQNNQNQNYDTVDMDSENEIEIARQQSIEHDGEENVDGDDNMDHDDDNNMEGGQSDNEKDANDDTADSQENIEEEDSVDIKPEDQMKDDDGQEEGEHEEVEINHNENEEEDDDDLPMSLAPVVEISEGLQGDSFNSEVVEEEEELDETVDPNDTIEEEEQVKELDPDKTYVTKTQRDFIQKYRDIIQQINTKRCLCCDREHPRRKAVIQHLQKNGHKVPKHTCYNCVITFGHIGALLSHMRSNSCTNLWKIIYNENGITDDLVLEDEPKEVKVAYKDIFNARSYACKLCPAKFQLKQFIMKHVLDTHEDGQSRVPLCCVHCRSRFKDKSLLKKHIRKGDCTVYIACDLCSEKFGNMQDFNDHALAIHAGSFDQSDNQSKCVDGRPTDCPLCGKKNSSYPNLVKHLKIIHAEEKPHYCQHCDSKFEQATDLNKHIYMEHSDRTLGMTPAEPDMSIVKEEAEEYHYSCTECNAIFETVDAWTDHQVAEHNQVAHHCDQCEKKFLRPSELAEHKNTHLRVKFYPCSVCPNSYSTPQKLSEHVQQSHPGIGAVAAAESEFFCDICIRAFKSRQAYSNHMRIHAKVPTTNRKPTPTKDGFTPQIIGKPIKQYPMVQPGFVSFKPNYNIPNAPYSCDICGKGFMHKKNIWKHKKVLHADILVDRHDSEENTMQASTEEEEFNPDENGAILSTPQFNSFNFSNFPNNTQQSTPETMPYSCELCSKRFPLKTSLWKHKRAKHGIVNPSTSGNNETSTPSASGESSSRSSCTICRITFSDKKSYYRHRKNVHKSTVQMCKICGKPLSSTLELYEHLKAAHARELLGYNANQGSSKSQDMAQEIEPDYENDQESLDPSVDYQARYPCDTCGKQFVGLLALQNHQCINQISSQPQTFDCEICHKSYTSISALKSHRGWHLRSPDGKAAANNSGLWMPQHKVTSKISKHEVVDASQLAKVTHTPTSPPVSATAAKRRLPPEVEVTVVNPNKKLRSDDSVDLDMQNSGTIEDRYCTICDKEFTKRAAYQRHMDEVHQPNSVFCPVCDKSFTRKSTLLIHMKKHYESGEGSSSATGQGDDDYSCDLCGAQYDNDQALRAHRARHHGEDEESAEESDDGNVPIAPPGEFTCAQCGDGVATPRDLIAHRTMHATPTKFFCNICKVYFARALDLSSHTRARHADNEKVFFPCAMCDRFYMNKKSLQRHIEMAH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00017541;
90% Identity: iTF_00758469;
80% Identity: -