Basic Information

Gene Symbol
-
Assembly
GCA_905220585.1
Location
HG992262.1:4537418-4549949[-]

Transcription Factor Domain

TF Family
AF-4
Domain
AF-4 domain
PFAM
PF05110
TF Group
Unclassified Structure
Description
This family consists of AF4 (Proto-oncogene AF4) and FMR2 (Fragile X syndrome) nuclear proteins. These proteins have been linked to human diseases such as acute lymphoblastic leukaemia and mental disabilities [1]. The family also contains a Drosophila AF4 protein homologue Lilliputian which contains an AT-hook domain. Lilliputian represents a novel pair-rule gene that acts in cytoskeleton regulation, segmentation and morphogenesis in Drosophila [2].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 2.5e-10 3.2e-06 27.2 0.0 3 76 44 119 42 132 0.87

Sequence Information

Coding Sequence
ATGCTCAGGTACGACAAGTGGGACCGGGGCGGGGGCGGCGGCGGCGCGGGCGGTGCGTGGGCGGGCCGCGAGCCGCGAGACGGTCGCGAGCCGCGCGCCGAGCCCCGCGATACACGCGACCGTGACACACGCGACCGCGAGCGCGACAGGGAGCGCGAGCGGCAGGCGCGCGCGCACCAGATGTCGCACGCGCACGCCGCCGAGCCCGATGCCTCGTCACTCTTCCCTGCACCTTTTAGAGTGACAGGAAATAGAGACCGCGTGAGCCAGCAGATCCAGATCAAACTCGGCGACTACAGGCTCGCTCAGACTTTGCTCGACGACCCTAGCAAATCTATCGGAATATGCGCCGAGCCACCCAGCCCCGCTCCCTGGCTGCGACTTCTAAGCGCAAGCATCGTTAGCAGAATTCACGACTGCTGTACAACATAG
Protein Sequence
MLRYDKWDRGGGGGGAGGAWAGREPRDGREPRAEPRDTRDRDTRDRERDRERERQARAHQMSHAHAAEPDASSLFPAPFRVTGNRDRVSQQIQIKLGDYRLAQTLLDDPSKSIGICAEPPSPAPWLRLLSASIVSRIHDCCTT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2