Basic Information

Insect: Noctua comes
Gene Symbol: egg
Assembly: GCA_963082995.1
Location: OY720295.1:6703606-6747637[+]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 2 5 1.6e+04 -3.8 0.1 29 38 1859 1868 1828 1869 0.69

2 2 7.2e-13 2.2e-09 37.4 0.0 4 73 1900 1962 1897 1966 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	2	5	1.6e+04	-3.8	0.1	29	38	1859	1868	1828	1869	0.69
2	2	7.2e-13	2.2e-09	37.4	0.0	4	73	1900	1962	1897	1966	0.88

Sequence Information

Coding Sequence: ATGAGTGATAAGGAAGAAAAAGACAATAAAGAGAAAGAAATTCCACGAAATAATCAAGACGGAGGTTCCAACAACCCAGAATCATTAACTGAGGGTAATGTACTATCTTTAGATTCGAATAAAAATACCGAAAATAGTAGCACCATATCTGAAAGTAAACTTCAATCAGCAGTTTTAGAAGGCTCTGGAGATAATGCCGGCCGCATTGTTCAAGAAAACTCGGAACTTGATAAAATAGAAGCAGAATTGACTGAAATGTCAAAGGAGTTGTTAGATACTGATGCAGGCATAGGCAGTGGTGATTATATAGCTACAGCAAAGGTCAGCGACGTAGATGATGAAATAATTGAGGACATAAATACTGAAATTAATGCTAAATCATCTAAAACCGTTGTAATTGCGGAGAAAGATGAAAGTAATGATGATCTTCTTGACAAATGTGATGATATAGAACTCAAAAAGACTGATGATTTTGACGAATTTGAAGATGAAGATATGCAACTAAGATGGGATGAGGATGATGATGCTAGCAATCAACTTCAGGGTGATGACACCACAAATGTTGGCAATAAGAATGATGGTATTCTGTCCGAAGACCAACTTTTGGAAGATTCTTCTGATGTTTTGACTGAAAAAGGCAATCTTGAAAGTGTAACATTAAGAGACAATTCTAAAGAATCAGAAACTAGCCTGAAACTGGACATCCATACAGACAAGGCTGATCTTGAAAAAAGCTTGGAAGAAGAGCTTTTAGAAGAACCTGATGTTAATACTGAAGCAATAAAAAGCCCTGAAATGGTTTTTTCTGCAGAAGAAAAAATGGAGCAACATTTCCTAGAAGAGAAAATACTTGAAGGCTCTGAAATGAACAGAGAAACAGAATTTATAGCTCAGGCCAAAGAGATTATTGACGTGAAAAATATGAATGAACAGATAAAAAACACTAACCCTGCAGAGAAACTAATAAAAGAAGATGAACTAACAAATTTTACTGAAACACTAGAAATGACATCTTCTAATAATCTTTTAGAAGAACCAGTTTCTAAGGACAAAAGTTCTGAAATTATTCCTGTAAAAGACACGGAAAGTTCTGACAACATTCCTGTAAAAGACACGGAAAGTTCTGACAACATTCCTGAAAAGGAATTCCCAATGAACAAAGAATTAGATGATGATGTTCTGCTAGAAGAAAAACTCTTAGAAGAACCTGAAAGAGCTGAAGTTATTCCTGAAAGTGATGTAACTATGGAAGTTGATGATGAAAATGAAGCTGAGTTACTAAAAGATGATGGTGGTCAAAACGATAGTAGTACTCCTATGGATGTTGACAGTACTGATCCATCTATTAAAGATCAAGCGAAGATAGAAGACACGATTATAGATCAGCCAATGGATGTTGAATCCGAAGTAGGGAAGAAAGAGATAGCTCAAACTTATCTAGAAAAGATTAATATAAACCAAACAACAGATGAAATCAAAGTAATGAATGAATCTGATGTGCAATTAGAAATGACTGAGAAAATCATTCATCAGCCGGTTGAAGATATAACTAAAACAATAGAGGTTATCAAAGATTTACCTGTTGAAGAAAAACCTGCAACAGTGGAATTTAATAAAGAGACAGCTATTGAGGATCAAGCTAAAATAGACGAGCAAAATATTGATTTAGCTGCATCAGAGACGGAAAATGTAAATCAATCAATGAATGATAAGAAGAAAATGGTTGAAAACAGCAAAGTTCAATTAATTGTAGAAACAAATACAATAGAAGAGTCTATCAAGACTCCTGAACAATTGGATGAAGTCACTGATTCTAATGTCCCTAACATTGAAATTGAACGACAGGAGAAATCTATCCCAGATAAATCTACACTTGAAAAGGTAATTGAAAGCAAAGAGGAGCAAGAGCAACCTAAATTAAATACAGAAAGTGTGCATGCAgacattaattttgaaaaacctgAAAAATCTAAAGAAATTGCTGTATTGGACACAAGCTTAGACAAAAACAATGAGACTGCTGAAGATTCATCTAGTTCTTCAATATTTCGAGATAGTCTGTCACCAATCAAAACTTTCCATGGTTTAAATAAACCAGATGTAATGCTAGAAATACCTACTCAAGAATTAATAGACATGGATATGACAGATTTATCTATGAATCTAGACCAATCAGAAGTTTTAGACAGTAGTGACAGAgatcaaaatatgaaaaaagatTTAGAAGATGACAGCACAATTGATATGTGTATACCTGAGGATGACACAGTAACTGAGACATCAGTAGATAATATAACTAATGTTATTGATGACACAGCAAACCAAAACACAGTAGATCAAGACACCATACTTACTGAAACAAAAGATGATAAAATTACCACAGCAAATGAGAAATCAGTAGATCCACAAACCACAGTAACTGAAGCAACAGTAGATGAATTACCAATAGaaagtaaaattgtaaaaagtggaaaaaaagaagaaactgTAGCTGAAGCGACTGTTGAAGAAACTATGGAAATACTGTTTGCTGATGTTGAACCCATGGTTGCTAAAGAAGTTCCTGAGTGCATTGCATCCACAAGCGAAACCCTGGAACAGCCATCGACATCCACCACACAAATGACTCCAGACACATCGGATGAACTTCCAGAGGTATCAGACAGTCTGGGGCTGTTGGCTGAGTCTACGCGGGTCATGGAAGATGACGAGGAAaacgaagatgatgatgatggtgacggtgatgatgatgatgatgacgattttgATCAGGATGaaaGCAGCAACCAAGTCTCGGCTGAACAGTCGGAAGACTCGAATCAAGCAGCCATAGAGTCCGAACCAGTCACAGAGACGGAGGAGAAGGAGTTGGAGACGCCAGACCCTAAGGAAAGCGAGTTTCCGTTCCTGCGTGACAGTTACTCACAGGATAAGGGGGAGAAGATCCATATGGAGTATGGCACGatgGAGTTACAGGCTGAAACAATAAATGAGATGAATCAAGAGGCAACATCAGCTGTAGCTGCGTTGTTGAATGCTGATAACCCCGTCATTGAACAAGCCAAGGCCCCAAAGGAAACCCCAGAAGAAATGGATATAGAAACAGTGAAACTGTCAGACACGTCTGACAATGAGGCTGACGTTGAACCTACTGTAGTTGAAAAGACTGTGGCTGAATCTAGCAAGGAGGTTGAAGAAGAGCAAAAGAAATCACCATCTAAATCCCCACTGCAAAGCAGTGTCTCCCCCAAGCAATCACCAAGCAAGCTGAAGAACTTAGCTATAACCGCGCAAGCGGCTAGATCCGTTGTTAATATTGTGGAATTGGAGGAGAGCAGCTCTTCAGACGATGATATACAAGAAACGGAAGTCCAAAAACAACCGTCACTGGAACCTGAGACAAAAGACGATAAACCTGCTTCCCCCGATCCGGACTCGGCAGTTACCAGCGTCAACATACCCACGGGCATAGACATAATACGTAGTGTGTCTTCCGGCGGAATTACCTCGGAGATAACAACTAAAGATGGGGAAGCTGTTATCAGTGGGGTACCTAAACCGCCGCCGCATAAGCCTgCCAGATTGAATATGAGTGAAGTTTCGATCAAAACTGTCAGTTCCACCGAACCAATGGTTATACCTGAAACTAAGATAAACGAACAGACCCCAACTCAGTCTAAACCTAAGCTGAGTCTAGAAATATTCAGTCTAGATTCTGACGAAGAAGATAGTTCTGCTAAAGaaaaatcCACAACAACACCTCAACACGAAATGACGGCGTTAGAACTGGAAAAAGCACGAGAAACATCGAAATGTATCAACTATGCTTGCACTAGCGACAACACAGTGCCATACAGGGTCGCGGAGGCAACAGAGATAGCGTACTACGACGCCAGCAGGAAGAGACGCGCCCTGGTGTGCCAGCCGTGCGCTGCTGTCGTCGCTGACAGGACTAAGAATCTAATCCAAGGCATGAAGGACCTAACTCCGCTCCTAGAATTAGACATGCGCAAGTCATCACAGGAACTGGTGGAGATATCAGATTCTGACTCTGAAGACGAGGATATGAATTCTGAGGAGCCGAAGGAGACCATTGGGAAAGAAGGGGCTAAaaTCATAGAAGAGAGTCTAAGTCAGTTTTTGAACGACACTTGGAAGAAATACAAAATGGATGCGCGGCTCAAAGAGACGCAGATCATGTTAGATGATGAAATCGAGAAACTAGAGCAGGACAGCAAGGAAATCGACTCAATGCTGAACGCATGTCAGGTGGCGACAGACAAGCTTCGCTGCGATCTGTACGCGACGTTCGAGTGTCGACTGCAACAGCTACCCCCAATTGTTATACAAGACACGCCTGAGAAAAAATATATTGGACAAGAAGAACAAGTCATCCCGCCTGTGGTTGGTGAATCAGCAGCGgtTCGTCATGCCAAGCGTCGTTTGTCGTCAACCTCCAATGAGCTGCCTGCCAAACGCCCCGCCATACCGCTTGGATATGCTCCTCTAGATTCTGCTGACGCTAAGGAAAAAGCAGCAATTCCTGCACCGGAAATTAAACTGGATGATGACAAAGACATATCAGTAGTGAAGCTATCAGCGGAAGCGGCCCCGGCCGACCTCCCCCCTCCGGGCGAGATCTCCCGCCCCCCCTTACGAGTGGGGATGCCGGTGTTTGCCATGAAGAACGCCTTCGGACCGTTTTTAAGAGGCAAGGTGCTGGAGATACAGCCCAAGAATCCTAGTGGGgGCAACCCGTTCTCTCTGTGCCGCGTGAGATTCGACCATAAGGCCAAAAGCAATGGGAAGGTGCTGCAAGCGAGGTCCATCGCTTATTCTGAGCCCGCTGATGTTAGAATGACAATTGGTACTCGCCTCATAGCCTTATTCAAGGATTCGAATAAGCGCGAGTCTTACTACTCAGGCGTGGTCGCTGAAATACCGAATCCGGTCAATAATTATAgATACCTAGTATTCTTCGACGACGGCTACGCTCAATACGTACAGCATCAGTATACCCGGCTTGTCTGCGAGAGCTCCTCTTTAGTATGGGAGGAAGTGCATCCATTCTCGCGGGAGTTCGTGCGCGAGTACCTGATGGCGTACCCTGAGAGACCCATGGTCAGGCTGCACACGGGGCAAAACCTGAAGACTGAGTGGAACGGAAAATGGTGGGCATCCCGGGTGAGCCGGGTAGACGCTTCACTAGCTCAGGTGACGTTCGTGGAGGACGGTCGGCGCGAGTGGATCTACCGCGGTTCAACACGACTCGCACCCTTGTATCTTGAACTTCGCGCCGCCGAGAGACACCGGCCCCGCCCCATGCCCCGGAGCAAGGCGCAGCCTAGGTTGAATATGCCGTACGTGGAGTACATTCGGTCGGATGAGCAGTCCGAGCAATCCAGCAAGCCACCAGACGTGCAGGTGCAGATTCAGCAGCAAATGCAACAACAACAGCTGCAGCGAGATGAGGAGATTCGCCGCCAACGCGCCGTGGCCAAGAAGTCCACATCAGCACCTCCTCAAGTGTACCCGCCGGCGCATCAGATCATGCCGCCCCTTAACACGGATCCTGTCACCAGCAGAGTTGTGtaCTACACACCAAAGAATGCAGTCAGGCCATTGAAGATGGTCCCGCATCGATGCACTCCAAAATGCAAGAGGAGTGACGTTCTCTCACTAAAGGAGTTGAGGACTTACAATCCGCTGGCCAAACCTCTACTTAGCGGATGGGAGAGACAAATAGTCCGCTTCAAGGGCCACAAGGACGTGATGTACCGCGCGCCCTGCGGCCGGCGCATACGCAACATGCGCGAGCTACATCACTACTTACGTTCCATAGACAGCGACCTGCCTGTAGATCTCTTCGATTTCCACTACTCCACGCACTGTCTGGCGGAGTTCGTGTTGAACAAGTGTCTTGTGGGGAAAAAGGACCTATCCCACGGCAAAGAGAACGTCCCGGTGCCGTGCGTGAACTACTACGACGACTCGCTCCCGGAGTTCTGTTCGTACAACACCGAGCGTACACCCACCGCAGGGGTGCCGCTCAACTTGGAGCCCGAATTCCTGTGCGGCTGCGACTGTACCGATGATTGTCAGGATAAATCCAAATGCGCTTGCTGGAAGATGACGCTAGAGGGCGCTCGGACCATCGGCCTGGTCGGGCCCAATGTGGGCTATGTCTACAAACGATTGCCAGAACCGTTACCTTCTGGAATATATGAGTGTAATTCTAGGTGCAAATGCAAGCATACGTGTCTAAATCGCGTGGCACAGCATCCACTGCAATTGAAGCTGCAGGTATTCAAAACTCCAAACCGCGGTTGGGGGATCCGCGCACTGAACGACGTGCCCAAAGGATCCTTCCTCTGTGTCTACGCTGGTAACCTGCTCACGGATGCTACGGCTAACTTGGACGGCTTAAATGAGGGCGACGAATATTTAGCCGAATTAGATTATATCGAAGTTGTTGAACAAATGAAAGAAGGGTACGAAGAGGACATCCCTGAGGCCATTAAGAAATTGGACAAGAAAGAATCAGGCAAGGATGGAGAAGACAGCGATGGagagccatcatcatcatctgaggATGAGGAGACCGCCTCCAAGACTGACAAAGAGGATGATGACTTCAGACCTGGGTACATTGGACTGGGACTGGGGGCTGGCGTTGCGGAGTTCAACAAACGCCTCCGTAAACGCGAGAAATCaaagaaagataaagaaaacGCGGCGGCTGACGATAAAGACAAAGATAAAGATACGACTAAAGATATAAAAGAACCAAAGGAAGCGAATGCTGAAGAAGATTGTATTACTATTAGCGATGATGAAGAAGGATACATCACTTGTACACTCAGGTGTGATGTAAACAAAAGAGAAGCAGACAATAAAACGAAAACTGCAAGGAGTAGTGATACTTTAGAGCCATCGGAGAACATAGAGGAACCAGTCAGTGCCGAGCAACCAGGACATGTAAAGACACCAAATGCTACTGAGCCACCACGCAATTTAGATCAACCAGAAGATGTAGTAACTACAGATGCTGTAGAGCCACCGGATGATGCGAGGCAACCACAAAATGTAGAGATAGAATTTCCTGTACGAGAACCTTCAAGATTCATGGCACAAACAAATATGGGAGCCAACGAGTATATATCTAAATACAAaTCTGTTCGCACACTGTTCGGTAAGGACGAGGCGTGCTATATCATGGACGCTAAGGTTCAAGGCAACATTGGCAGATATCTCAATCACTCCTGTTGTCCCAACGTATTCGTACAAAACGTCTTCGTGGACACCCACGACCCGCGCTTCCCCTGGGTAGCGTTCTTCGCACTATCGCACATAAAGGCGGGTACAGAGCTCACGTGGAACTACAATTATGACGTGGGTTCGGTGCCCGGCAAGGTGCTCTACTGTTACTGCGGCGCCGTCAATTGTAGGGGGCGGCTTTTGTAA
Protein Sequence: MSDKEEKDNKEKEIPRNNQDGGSNNPESLTEGNVLSLDSNKNTENSSTISESKLQSAVLEGSGDNAGRIVQENSELDKIEAELTEMSKELLDTDAGIGSGDYIATAKVSDVDDEIIEDINTEINAKSSKTVVIAEKDESNDDLLDKCDDIELKKTDDFDEFEDEDMQLRWDEDDDASNQLQGDDTTNVGNKNDGILSEDQLLEDSSDVLTEKGNLESVTLRDNSKESETSLKLDIHTDKADLEKSLEEELLEEPDVNTEAIKSPEMVFSAEEKMEQHFLEEKILEGSEMNRETEFIAQAKEIIDVKNMNEQIKNTNPAEKLIKEDELTNFTETLEMTSSNNLLEEPVSKDKSSEIIPVKDTESSDNIPVKDTESSDNIPEKEFPMNKELDDDVLLEEKLLEEPERAEVIPESDVTMEVDDENEAELLKDDGGQNDSSTPMDVDSTDPSIKDQAKIEDTIIDQPMDVESEVGKKEIAQTYLEKININQTTDEIKVMNESDVQLEMTEKIIHQPVEDITKTIEVIKDLPVEEKPATVEFNKETAIEDQAKIDEQNIDLAASETENVNQSMNDKKKMVENSKVQLIVETNTIEESIKTPEQLDEVTDSNVPNIEIERQEKSIPDKSTLEKVIESKEEQEQPKLNTESVHADINFEKPEKSKEIAVLDTSLDKNNETAEDSSSSSIFRDSLSPIKTFHGLNKPDVMLEIPTQELIDMDMTDLSMNLDQSEVLDSSDRDQNMKKDLEDDSTIDMCIPEDDTVTETSVDNITNVIDDTANQNTVDQDTILTETKDDKITTANEKSVDPQTTVTEATVDELPIESKIVKSGKKEETVAEATVEETMEILFADVEPMVAKEVPECIASTSETLEQPSTSTTQMTPDTSDELPEVSDSLGLLAESTRVMEDDEENEDDDDGDGDDDDDDDFDQDESSNQVSAEQSEDSNQAAIESEPVTETEEKELETPDPKESEFPFLRDSYSQDKGEKIHMEYGTMELQAETINEMNQEATSAVAALLNADNPVIEQAKAPKETPEEMDIETVKLSDTSDNEADVEPTVVEKTVAESSKEVEEEQKKSPSKSPLQSSVSPKQSPSKLKNLAITAQAARSVVNIVELEESSSSDDDIQETEVQKQPSLEPETKDDKPASPDPDSAVTSVNIPTGIDIIRSVSSGGITSEITTKDGEAVISGVPKPPPHKPARLNMSEVSIKTVSSTEPMVIPETKINEQTPTQSKPKLSLEIFSLDSDEEDSSAKEKSTTTPQHEMTALELEKARETSKCINYACTSDNTVPYRVAEATEIAYYDASRKRRALVCQPCAAVVADRTKNLIQGMKDLTPLLELDMRKSSQELVEISDSDSEDEDMNSEEPKETIGKEGAKIIEESLSQFLNDTWKKYKMDARLKETQIMLDDEIEKLEQDSKEIDSMLNACQVATDKLRCDLYATFECRLQQLPPIVIQDTPEKKYIGQEEQVIPPVVGESAAVRHAKRRLSSTSNELPAKRPAIPLGYAPLDSADAKEKAAIPAPEIKLDDDKDISVVKLSAEAAPADLPPPGEISRPPLRVGMPVFAMKNAFGPFLRGKVLEIQPKNPSGGNPFSLCRVRFDHKAKSNGKVLQARSIAYSEPADVRMTIGTRLIALFKDSNKRESYYSGVVAEIPNPVNNYRYLVFFDDGYAQYVQHQYTRLVCESSSLVWEEVHPFSREFVREYLMAYPERPMVRLHTGQNLKTEWNGKWWASRVSRVDASLAQVTFVEDGRREWIYRGSTRLAPLYLELRAAERHRPRPMPRSKAQPRLNMPYVEYIRSDEQSEQSSKPPDVQVQIQQQMQQQQLQRDEEIRRQRAVAKKSTSAPPQVYPPAHQIMPPLNTDPVTSRVVYYTPKNAVRPLKMVPHRCTPKCKRSDVLSLKELRTYNPLAKPLLSGWERQIVRFKGHKDVMYRAPCGRRIRNMRELHHYLRSIDSDLPVDLFDFHYSTHCLAEFVLNKCLVGKKDLSHGKENVPVPCVNYYDDSLPEFCSYNTERTPTAGVPLNLEPEFLCGCDCTDDCQDKSKCACWKMTLEGARTIGLVGPNVGYVYKRLPEPLPSGIYECNSRCKCKHTCLNRVAQHPLQLKLQVFKTPNRGWGIRALNDVPKGSFLCVYAGNLLTDATANLDGLNEGDEYLAELDYIEVVEQMKEGYEEDIPEAIKKLDKKESGKDGEDSDGEPSSSSEDEETASKTDKEDDDFRPGYIGLGLGAGVAEFNKRLRKREKSKKDKENAAADDKDKDKDTTKDIKEPKEANAEEDCITISDDEEGYITCTLRCDVNKREADNKTKTARSSDTLEPSENIEEPVSAEQPGHVKTPNATEPPRNLDQPEDVVTTDAVEPPDDARQPQNVEIEFPVREPSRFMAQTNMGANEYISKYKSVRTLFGKDEACYIMDAKVQGNIGRYLNHSCCPNVFVQNVFVDTHDPRFPWVAFFALSHIKAGTELTWNYNYDVGSVPGKVLYCYCGAVNCRGRLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01533075;
90% Identity: -
80% Identity: -