Basic Information

Gene Symbol
-
Assembly
GCA_964007305.1
Location
OZ023257.1:9589811-9593766[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 0.1 12 7.2 0.2 2 23 228 250 227 250 0.91
2 18 0.16 18 6.6 0.5 1 23 262 285 262 285 0.95
3 18 0.014 1.6 9.9 4.9 1 23 298 321 298 321 0.94
4 18 0.0011 0.13 13.4 4.8 1 23 327 349 327 350 0.93
5 18 0.023 2.7 9.2 0.4 2 23 356 378 355 378 0.95
6 18 0.0009 0.1 13.7 1.2 1 23 383 406 383 406 0.98
7 18 7.6e-07 8.8e-05 23.3 0.5 2 23 413 434 412 434 0.96
8 18 6.8e-07 7.9e-05 23.5 0.3 1 23 440 462 440 462 0.96
9 18 0.00014 0.017 16.2 1.0 1 23 468 490 468 490 0.97
10 18 0.00012 0.014 16.4 5.6 3 23 610 630 609 630 0.97
11 18 0.00022 0.026 15.6 0.5 1 23 632 655 632 655 0.95
12 18 0.0017 0.19 12.8 2.1 1 23 660 683 660 683 0.96
13 18 4.9e-05 0.0057 17.6 2.0 1 23 689 712 689 712 0.96
14 18 0.0013 0.16 13.1 2.0 2 23 719 741 718 741 0.95
15 18 0.0022 0.26 12.4 0.3 1 23 746 768 746 768 0.96
16 18 0.00078 0.09 13.9 0.5 3 23 776 795 775 795 0.98
17 18 7e-06 0.00082 20.3 0.1 1 23 801 823 801 823 0.97
18 18 0.0055 0.65 11.2 0.7 1 23 829 851 829 851 0.97

Sequence Information

Coding Sequence
ATGAAGAAATGGCAAATATTGGAATTCGACGGTAAGGCATACTACGCATTCGTGCCGGAGAATGATGATCCTTTCGACACGGGTTGCACACCCGAAGTGGAAAGCAGAAGCGCTCCGTGTTTCAAGGAAGAAACAGTCACGGGAGATTATATCTACGAGGATTATTCCCCGGAAAACGACGCAAGTTTTTCCAAATACGACGAGTCAAACGACGAGGAGGAGCAACCCGAATTGGACGAGACGAAGCCGTCATTATTGAACACGTCGGAAGGCGCGACTCGAACTAAATCTCTTGGTAATTTATATCAGGTCAAGATCGAAGCAAGCACAGTGACGTTGGAGAGGCTTGCTGAAGGAGTCGAGACCGACGGGGAGATGCAGATGCCCGAAACGATGAAACAAGAGCCCTCGACCGAGCTATCCGATTACGAAATGAACGAGACACTCGAAGAAGATCTGGAGGAGGAGGATTTTGTCGAGGATTCAATCGTCGATAATTCTATGGAGGATTTGATCGCCGAGGAACGCCAAGGAGAGCAAGaggagaacgaggaagaagaagccGACGAGCaggaagaaggagaggagTTAGTGACTGAAGAGAAGACAGTACAATATCGATTTCAAGAACCTTCGAAAAATTTCACCGCGACAATGACGAAAATGACCGGAGGACCTCTCAAGTGCAAAGCATGCTCGGAAACTTTTGGTTCGGAGATGGCCTTTAAAAAGCACGTAGCCTGGACCCACAAGAAGAAAGTTTGCATCCAAGAGGCCGGTGCTTATATATGCTCGGTCTGTGATTACAGAACGTTGAAGAAATCCTTGTTCGCCGCTCATCTTGAGAGAAAACACGAGACATGGACGAGAAAGCGACAGAACAGTCTCGTCTTCCCCTGCGAAACTTGCGGTTTCATCTGTCGCTCCAAACACTCGTTGCAGTCACATTTCATCAGGAAACACACCGACAGATTCGAACATGACTGTAATTTTTGCGCAAAGAAGTTCAAGGTTAAGGGCGATTTGACTAATCACATAAGATTTCATCACAAGGAGAAACCTATCAGCTGCGACGTTTGCGGAAAATTGTGCCAGAACACGGGTTCCCTTTACGTTCATCAAAAGTGGGCCCACTATAAGCCAAAGTACGAGTGTCACATATGCAAGCGTCGTATGGTAACGCAGGAAAATCTGGATCAACATCTTATCACGCAACACGAGCGACGTGAGAAAATCGTTTGCGCACAGTGCGGCAAGACTTTCACGAAGAAGGACTCGTTCAGGCGACACATGGCTGTACACTCGGGATGCAAACCTCATCCTTGTCCGATATGCACCAAACCATTCGCTCGTCAGTCTCAGCTTAGACAGCACGTTCTCATACACACCGGACAACGTCCTTTTATTTGCGACATATGTGGCAAAGGTTTCACTCAAAAACCAGGACTGATCTGTCACAGAAAAACCCACCCAGGACCTCATGCACCTTTACCAGTCATGCCCATAGCCGACCTCGTTAGAGATTTTATCGCTCAGAACGAGGAGAGTCAGAGTCATGATCTCGATTTGGAaaATCTGCAACGAGATCCTCTGACCATatcggaaaataaaattgcgccACGACGTCTCCGATCTATTACGACTTCCGGATACAAGAGTCTAAAAccgcaaagaagaaaaaagtggaCTATCGACAAGAAGGACGTTTGCCATCGAGAAAGAAGAATCTCGCTCGagaatttgtcgaaagaatcTTGCCAAGTTGACACGATCGTATCATCGAAAGCATCGATCTCGAAAGGATCCGTCGCTCGAATTAGCGTTGACTGTCACCATTGTGGAAGAAAATTTCAGAAGAAGAGTAATCTGATCGAGCACCTCAAACAGCACAGGCACAAATGTCTCGAGTGTCCGAAAACTTTCAGTCTCGCTCGTTATCTCGAAGCTCACGTTGACAAGGTCCATCGTCTTCACGTACACGAGTGCAGCGTGTGTGATTACAAGAGCAACAACAAGGGTACTCTGAAAAATCACTACATCAGATTACACACGAGCAATTACGAGTATTCCTGCGAGATCTGTGGTAAACAGTTCAAGATAAAGAAAGCACTGAATCATCACGTGAAACAAAGTCATAGTGATTTGCCACCGATAGTTTGCGACGTTTGCGGTCACTTCAGCAAAAATCTTCACGCTCTCAAAGCCCATATGAAGTATCGTCACTACAAGCCcgaatttatttgtaaaatatgcAGACGTGGTATGACAACCAGAGAAAATTTGGAGCAGCACATAACTTGGCACGAAACTCGCGAGAAAGTGTTGTGTCCAACTTGTGGCAAGAGATTTCGTGGCCGGGATCTTGACTCTCACATGAGAGTTCACACGGGTGTAAAGCCTTTTCCATGTCCAGTTTGTGGCAAAACTTTTCGACGTCAGACAGCTCAGGAACAACACGTTCTCATTCACACTGGAAAAAGACCATACGTTTGTGATATCTGTAGTCAAGCCTTCGCCCAAAAGCCAGGACTGATCTGTCATCGAAAGAGACATCCGGGGCCGTTACCACCGTTGCCCATAGTTTCTATTAAAAAGATCGTTACCGAATTCACTCGCGAATACACGAgcagaaaaattcagaacTGA
Protein Sequence
MKKWQILEFDGKAYYAFVPENDDPFDTGCTPEVESRSAPCFKEETVTGDYIYEDYSPENDASFSKYDESNDEEEQPELDETKPSLLNTSEGATRTKSLGNLYQVKIEASTVTLERLAEGVETDGEMQMPETMKQEPSTELSDYEMNETLEEDLEEEDFVEDSIVDNSMEDLIAEERQGEQEENEEEEADEQEEGEELVTEEKTVQYRFQEPSKNFTATMTKMTGGPLKCKACSETFGSEMAFKKHVAWTHKKKVCIQEAGAYICSVCDYRTLKKSLFAAHLERKHETWTRKRQNSLVFPCETCGFICRSKHSLQSHFIRKHTDRFEHDCNFCAKKFKVKGDLTNHIRFHHKEKPISCDVCGKLCQNTGSLYVHQKWAHYKPKYECHICKRRMVTQENLDQHLITQHERREKIVCAQCGKTFTKKDSFRRHMAVHSGCKPHPCPICTKPFARQSQLRQHVLIHTGQRPFICDICGKGFTQKPGLICHRKTHPGPHAPLPVMPIADLVRDFIAQNEESQSHDLDLENLQRDPLTISENKIAPRRLRSITTSGYKSLKPQRRKKWTIDKKDVCHRERRISLENLSKESCQVDTIVSSKASISKGSVARISVDCHHCGRKFQKKSNLIEHLKQHRHKCLECPKTFSLARYLEAHVDKVHRLHVHECSVCDYKSNNKGTLKNHYIRLHTSNYEYSCEICGKQFKIKKALNHHVKQSHSDLPPIVCDVCGHFSKNLHALKAHMKYRHYKPEFICKICRRGMTTRENLEQHITWHETREKVLCPTCGKRFRGRDLDSHMRVHTGVKPFPCPVCGKTFRRQTAQEQHVLIHTGKRPYVCDICSQAFAQKPGLICHRKRHPGPLPPLPIVSIKKIVTEFTREYTSRKIQN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01057822;
90% Identity
iTF_01057078;
80% Identity
-