Nmel024328.1
Basic Information
- Insect
- Netelia melanura
- Gene Symbol
- -
- Assembly
- GCA_964007305.1
- Location
- OZ023260.1:9705577-9710185[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 19 0.015 1.8 9.8 2.0 1 23 356 378 356 378 0.95 2 19 0.03 3.4 8.9 0.6 2 23 427 448 426 448 0.95 3 19 0.00039 0.045 14.8 0.1 1 23 524 546 524 546 0.94 4 19 0.001 0.12 13.5 1.3 1 23 550 572 550 572 0.96 5 19 0.00096 0.11 13.6 3.5 2 23 671 692 670 692 0.97 6 19 0.00012 0.014 16.4 1.7 2 23 698 719 697 720 0.94 7 19 0.00054 0.063 14.4 0.4 1 20 727 746 727 751 0.92 8 19 0.00011 0.013 16.5 2.3 1 23 848 870 848 870 0.97 9 19 5.6e-05 0.0065 17.5 3.9 1 23 926 948 926 948 0.97 10 19 0.0006 0.07 14.2 1.1 1 20 953 972 953 974 0.94 11 19 0.038 4.4 8.5 0.6 2 23 985 1006 985 1006 0.97 12 19 1.4e-05 0.0017 19.3 0.7 2 23 1045 1066 1044 1066 0.97 13 19 2.9e-05 0.0034 18.3 1.6 1 23 1071 1093 1071 1093 0.95 14 19 9.4e-05 0.011 16.7 1.8 1 23 1099 1121 1099 1121 0.98 15 19 5.2e-06 0.0006 20.7 0.4 1 23 1137 1159 1137 1159 0.95 16 19 1.6e-06 0.00019 22.3 0.3 1 23 1165 1187 1165 1187 0.99 17 19 3.1e-05 0.0036 18.3 0.3 1 23 1193 1215 1193 1215 0.98 18 19 0.00017 0.02 15.9 4.1 1 23 1221 1243 1221 1243 0.96 19 19 0.012 1.4 10.1 0.4 1 20 1249 1268 1249 1270 0.89
Sequence Information
- Coding Sequence
- atggacGCCGTAGAGATTGCTACGGCGGAGGAATCTCACAACGAAGACACGATAGAGGAAACCGTGCCCGAGGTCTGTCGTGTCTGTTTGCTCGGGCATGTAATAATGCGCGATCTTTTCGTCGAGAACGAGGTCGTCTCGCTCTCGACCAAAGCCATGAGCTTCGCCAGCGTCAAGATGTTACCCGAGGATGGTTTGCCGGGCCAAGTTTGCTGCGAATGTGCGGACAAGCTAGAAGCGGCGTACGAGTTTAAACTGCAGGTGGAGCAAGCCGATAATGTATTGAGACAGAGATACGACACTTTGAATATCAAAGAAGAgcttttcttcaacgaggtcGAGGTTCATCTTGAGGGCGACAGAGGTCACGGTGTTCACTCTTTAGACGTCGATGCTCATTATCAAGCGACGGTGGACAGTTTGAACGCGGTCGAGCCGGAGGATGAAAAACCATCGCTGCTGAAGGATCATCTGGCGCTCCTGGAAGTTGAGAAACTTGCGAAAGAACAGGATGAGCTCGAAGCTGAGAACAAAAACGTCGTTTCGATGGaagaagagagcgaggtggCTGAAATTCTTCGAGGAGACGATGATCATGCGGATTATCTGCGAGACGACGATGGAAATGTCGAGGAATTGGTTGATTACGGAGATACGGAAAAAACCGAGAGTATGCATGTTCCTGAAGGCGTAACCGTTGAGGAGCATAATTACATAATGCAACAGGGTTACTCATTAGCGCCTAACGAGGAAGAGTTGGGGACACGAGAAAGCTGTGATTCCGCAGCGAATGACGAGTCCGTGAATTATCTGTCCCTCATGGAAGACGATATGAGCGTCGAGGATGACCCGAACGAGTCGGAAATCTTGAATAGCGTCGATCCCGAAGAGCAGGACGAAAAGGCATTggtgaaagaagaaatttcGCCCTGCGAGACAAGGCGCAGTAAGCGAAAATTGACAAAACGCTTGCGCGATACCGACGAGGACaattactttgagaatttgaATCTCAGCAGTCGTTTGAAAAGATCGCAGACCATCGAGAAGggtgacaaattttattttctctgttATCTCTGCGACAAGCAATTCGTATCGAAGGAAATACTGAAAGAGCACATGCATTCTCACGAGGAGGTCAGACGTACGATGTCGTTGAAGAAGAacgaaaagggagaaaaacgtTTGGGGAGTCCGACGAAAACACCAACAGCGCCAACCACAACAACTTCGCCAAGCTCCGCTGGACAATCAATGTCTGGTAAAAAGGCCAACAAATGTCCTTACTGCGGCAAGGAATATCTTTATGTCATATCATTCAACAAGCATCTCAAACAACACGAGAAGAACAAAGAATCGTCGACGGGAACCTGGCCAGAAGAGCCGATGGACACAGCTGAAGATTCCTCCTCGGATTTCGTAGGTTACGACGAGACAAGAGTGTCCGAGGCAACGTCTCGCGTTGAGGCGAGCAACGATGATGTTTCCATCGATTTAAACGCTGAAGAAACGAGTCCGGGGAGAAGACATGCCCGACGACGTTCCATTCGTAACGAAACTCCGGCTTTCACTTGTGAGAAATGTCCGGAAAGATTCGCTAATAAACGTGACCTTGCTGAGCACGCTATCGACCACTGTACAACCTTCAAGTGTAGCACGTGCGATCGTGAGTTCGACGGTCTCGAGAAGCTTCGACGACATCGTACCGAGCACGTGGTCGAGGGTGTCCTCTCGGAGCAGGATCTCGAGGGTAACGTGTACGAAAGGGAATTCGACGAGGAAGCAGCAAACGACGCTGATAATGAGATTTTTGGGGAAATGGGAGAAGGTCAAAGCGAGGATGTTGGAAGTCAGGAACAAGTGAATGAAGCGGATGGCGAGAATAATTGGCGATTGGTCGGGATTGAAGGTGACGACTCTGCGGATGGTAAAGGTCCATTGGTACAGGAGACCGATGAACCCTCGACTGAAAGCGTGCCTGGAAATTGGCCAGAAACGCGCAATCTCAGGTGTCCTCATTGCTCTATCTACTGTTCCAGTAAAAAGTCACTAGCTCGTCATATCGAGACACACGATGCTTCCAGGCAAGTCTGTAAATTGTGCAAAATGGAATTTCCAAGGAAGGAACAGTTGCAGCGTCACATCGAGCAACACCACAGCGGTAGAACTAAGTCTTTCAACTGTACCGATTGCGGTAAGGTCTTTGGTAACGAGCTTACCCTTAGAAATCATTTATTCGCTACAAATCACAAAACGATAATGCATGGACAGCAATACGATCCTAACAAAAGATTGAAACGCGTTGCTGCTAAAGCGGCGCAGAGAATAATCGACAAAATCAAGACGGAGGATGACATGGACGAGGAAGAAACCGACAGGATcgacgaggaggaaagaaCGGAGGAGAACGACGGGGAAACGATGGAAGGACGAAACTCCAGGTCGAGCAACGCTCGTTGGTCACGTCAGGTTGAGAGACAACAAGGCGCTGCCTCAAGGAGAAAAGTTCAGCAACATCGTGGTCGTCGAAGATGCGATTATGAGTGCGAAGCTTGCGGTCGTAAATGCAGCTCTAAGCAATCCTTGACGAAGCACATGGAGCAGCATCGTGTCAAAGACGAAAAGATGGAGTCACCAGAAAAATCCAGAAGAAACGACATGGAGCGTGGTTTGCGTCAACCAAGCTCTAGAATCGATGAGAAGAATGAGGAAGAAACAGAGAACGATGAGAATTCTGATTTCGAGAGCGGTCTCGATTGGCCAATGGACAATCATGAGTGTCCAACCTGCAAGAAGAAATACAGCACGAAAAAATCCCTTCTGCGCCATCAGCTTTTGCACGAGGAGCCAAACTTTGAATGCGACATTTGCAACGTCAAGTTTTATCGCAAGGACAAACTCAAGTCGCACTACGACAAATGCTCAGAGAAGAATCCGGATCAAGTCAGAAAATGCAATATATGCGGGGACAGTTTTGAGaacaatgaaatattgaaGGAACACAAGAATCGTCACGTCGATGAGGGAATTCTCACCGAGGAGGATCTTCGAGACATAGAACCAGGCTTCGAGGAGAGACGAGAGTCCCGTAAGGtagcaagaaaaagaagagacgatATCGTTGGTCTCGAATGCACCGAGTGCAACAAACGTTACACCTCGCGCAAAGGATTGCTGCGACACATACAAGTACACGAGGGTAAGAAGTATCTCTGCGATATTTGTCCCAAGAAATTTTATCGCCGTGAACATTTGAAGATCCATGTCGCGAAGCACAACATGATAAAGCCTTACAAGTGTCCACGCTGTACCAAGCGTTTCATCAAAGAGGAACAATTATCGAATCACTTGTCCAAACACGATAGAACCTTCAAAAAACCCAAGGAGGCAGACACCGCCAAGAGATTCTTGTGTGAAATTTGTTCCAAGAGCTTTACTCAGTCAACGACCCTGATAGCGCATCTCAGAGCTCATAATGGTATTAAACCTTACGTTTGTGAAGTTTGCGCACGTCCTTTTACCACCAACGCTTATTTGAAAATGCACATGAGGACTCATACTCAGGAGCGACCTTACAGTTGTCAATATTGCTCGAGAGCATTTGCTCGTGCAGACACTTTGGCGAATCACCTAACCTCACATACCGGCGAGGCGAAATATCATTGCAAATATTGTCCGAAGAACTTTCGACGCCTCAAATCACTCAAGGAACACGTTTTTATTCATACGGGTCAACGACCTTACGCTTGTCCTACCTGCGATCGTCGTTTTAATAATAACGGCAGTCGTTACGCTCATAGCAAGAGATGCAAACAAAATGTCATGCAGAGTCAGAATCGACAACAACCCGGTCACATGACCGGCGCCATCTTGCAAAATACCATGGCTCAGCCAATAAGGTTGCATCAGTTCACGGGCCAGGAACACAGTTCGCAGATGCAAGTTGTCAAGTCTCAGAGTATCAAGACGATCACGATTGCGAGACAGAGCGATCAATTGACCGGACATCAAGTTATGCAACATCAAGAAATTCTCATGCCGCTTATTTTACCGCTTACCGTTACCCTCACGGACGTTGACGAGGAGGTCATTTTACCGGAGGGCACGAAGATCTTTACCACGGCTTGA
- Protein Sequence
- MDAVEIATAEESHNEDTIEETVPEVCRVCLLGHVIMRDLFVENEVVSLSTKAMSFASVKMLPEDGLPGQVCCECADKLEAAYEFKLQVEQADNVLRQRYDTLNIKEELFFNEVEVHLEGDRGHGVHSLDVDAHYQATVDSLNAVEPEDEKPSLLKDHLALLEVEKLAKEQDELEAENKNVVSMEEESEVAEILRGDDDHADYLRDDDGNVEELVDYGDTEKTESMHVPEGVTVEEHNYIMQQGYSLAPNEEELGTRESCDSAANDESVNYLSLMEDDMSVEDDPNESEILNSVDPEEQDEKALVKEEISPCETRRSKRKLTKRLRDTDEDNYFENLNLSSRLKRSQTIEKGDKFYFLCYLCDKQFVSKEILKEHMHSHEEVRRTMSLKKNEKGEKRLGSPTKTPTAPTTTTSPSSAGQSMSGKKANKCPYCGKEYLYVISFNKHLKQHEKNKESSTGTWPEEPMDTAEDSSSDFVGYDETRVSEATSRVEASNDDVSIDLNAEETSPGRRHARRRSIRNETPAFTCEKCPERFANKRDLAEHAIDHCTTFKCSTCDREFDGLEKLRRHRTEHVVEGVLSEQDLEGNVYEREFDEEAANDADNEIFGEMGEGQSEDVGSQEQVNEADGENNWRLVGIEGDDSADGKGPLVQETDEPSTESVPGNWPETRNLRCPHCSIYCSSKKSLARHIETHDASRQVCKLCKMEFPRKEQLQRHIEQHHSGRTKSFNCTDCGKVFGNELTLRNHLFATNHKTIMHGQQYDPNKRLKRVAAKAAQRIIDKIKTEDDMDEEETDRIDEEERTEENDGETMEGRNSRSSNARWSRQVERQQGAASRRKVQQHRGRRRCDYECEACGRKCSSKQSLTKHMEQHRVKDEKMESPEKSRRNDMERGLRQPSSRIDEKNEEETENDENSDFESGLDWPMDNHECPTCKKKYSTKKSLLRHQLLHEEPNFECDICNVKFYRKDKLKSHYDKCSEKNPDQVRKCNICGDSFENNEILKEHKNRHVDEGILTEEDLRDIEPGFEERRESRKVARKRRDDIVGLECTECNKRYTSRKGLLRHIQVHEGKKYLCDICPKKFYRREHLKIHVAKHNMIKPYKCPRCTKRFIKEEQLSNHLSKHDRTFKKPKEADTAKRFLCEICSKSFTQSTTLIAHLRAHNGIKPYVCEVCARPFTTNAYLKMHMRTHTQERPYSCQYCSRAFARADTLANHLTSHTGEAKYHCKYCPKNFRRLKSLKEHVFIHTGQRPYACPTCDRRFNNNGSRYAHSKRCKQNVMQSQNRQQPGHMTGAILQNTMAQPIRLHQFTGQEHSSQMQVVKSQSIKTITIARQSDQLTGHQVMQHQEILMPLILPLTVTLTDVDEEVILPEGTKIFTTA
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01057076;
- 90% Identity
- iTF_01057820;
- 80% Identity
- -