Ngue009674.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Nephrotoma guestfalica
Gene Symbol
ZFY
Assembly
GCA_963691935.1
Location
OY829913.1:135342732-135345391[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 20 0.021 4.2 9.8 1.7 3 23 119 139 117 139 0.97
2 20 0.002 0.4 13.1 4.3 1 23 145 167 145 167 0.91
3 20 7.3e-05 0.014 17.6 2.0 1 23 179 201 179 201 0.96
4 20 1.6 3.1e+02 4.0 1.8 1 23 207 230 207 230 0.87
5 20 1.3e-07 2.6e-05 26.2 0.8 3 23 255 275 254 275 0.98
6 20 1.5e-05 0.0029 19.8 1.3 1 23 281 303 281 303 0.97
7 20 0.00013 0.026 16.8 0.9 1 23 309 332 309 332 0.95
8 20 0.00065 0.13 14.6 1.3 1 23 344 367 344 367 0.94
9 20 1.3e-06 0.00025 23.1 0.3 2 23 440 461 439 461 0.96
10 20 0.00082 0.16 14.3 3.0 1 23 467 489 467 489 0.99
11 20 0.0086 1.7 11.1 0.3 1 21 496 516 496 519 0.89
12 20 0.0035 0.69 12.3 0.4 2 23 527 548 526 548 0.95
13 20 3.1e-05 0.0061 18.8 5.7 1 23 586 608 586 608 0.99
14 20 0.00061 0.12 14.7 1.3 1 23 614 636 614 636 0.97
15 20 0.015 2.9 10.3 1.4 1 23 642 664 642 664 0.96
16 20 9.9e-06 0.002 20.3 3.7 1 23 670 692 670 692 0.98
17 20 7.4e-05 0.014 17.6 1.6 2 23 723 744 722 744 0.97
18 20 0.00011 0.021 17.0 1.7 1 23 750 772 750 772 0.97
19 20 0.0005 0.098 15.0 2.6 1 23 779 801 779 801 0.98
20 20 0.13 25 7.4 3.8 1 23 807 829 807 829 0.95

Sequence Information

Coding Sequence
ATGGATTcacaattatacattttatttaataataacgtGCTAACGCCAATTGATCAATCGAATATATGTTATGTAATTGAGTCCGGACTGCTAGTGCCAATATCCAATGACATTAATTCTATAAACCCTGTTGAAGAACCTTTCGTAACTTCCGAGGAGTTTATTTGCAATTATGATGAACAAATAATACCAATCAACGAAGAGGAATTCAGTACTTCCGGTTTATCAATGCCAATTGATGATGGATTTAACGAGATCTTCATGGAATATAATGAGGCCGAAAGTACTAGGCTTCCAAACGAACTATATATCAATTCAACATCTGACCCATCAAATACTAAAAACTCTTATGGGTGTGAACACTGTGGAATCAAGTTTCTACAAATAAAACTGTTGAATCGGCACAAGATGACACATATTTACGAGAAACCATTTAAATGCAACCAATGCCAtgagagttttaatttttcggtcaatttaaaaGTGCACAACACGTTCCACCAAGATCCATTGGTCAATTCCGGCAGACCAAGACATGTGTGCAGTgtatgcaataaaatatttcgccgCTTTTCAAGTTTACGCGGGCACCTCAAAGGGCATTCGGTCTCGGATTATTTTAATTGCGATCAttgcaatgaaatatttttggcaaaatcattttacgaaaatcatttGGATAATTACCATAAAAAGGAAGATAAGGAACGTAAAACTGTTAAATTACCTAGTGGTGGTAATGTTGCCAATATTGGACGAGACTGTAAATTATGtggaaaatcatttaaaaaacccAGTATGCTGGTTCGCCATATGCGAGTGCATAATGGTGACAAACCATTTAATTGCGGTACATGCGGTAgacaattttctcaaaaaaactCTCTCAAAATACATTTGCTTCGGCACACAGGAAGAAAACCGTTCGCTTGTACGTTGTGTTCTATGCGATTCACACAAAAAGGAAATCTAAAGATTCACAAGGAAAAAGTACATAACAAATTCAGCTCGAATACGGAGGCCACAAAATATCCCTGCAATAAATGCTCATGCGTATTTCGTAAAATCGGCTCACTCAATCGGCATATCACGGAAGTGCATAGTGCAAGTAATCGGAAAGGAACGACGTCTAATGGAGAAATTAATTTCAACGAGATTATGTCCCAAATCAATGATCTTAAACAAGCACCTCCTATTCCTGAAACTTCAGAACAACAAGGCGATGATATTATTCAGTTAGCCGATCGACTAGAAAACGGTATTTTAATTCATCGTAAAGTACAACATTTGAGTACCCACCGGGGTAAAAATATGTTAAGTTGCCTAAACTGTGGAAAACTTTTTACTCGACCATCGGACTTGCTACGACACATTCGTGTGCACACGAAGGAGAAGCCGTATGAATGCTATCTATGCAAACGTCGTTTTTCCGTCCAGAGAACTCTCTCACTTCACTACAAAACACATGAAAGCGCTTTGCGCAAATTTTCCTGTAGTGTGTGCAGTAAAAATTTTCGTGATGTTGCCACCCTGTTAGTGCACGGGACTGAATACCATCAAAATTCTAGTGACTATTTGCAGTGTTTTCGATGCAAATTGATTTTCTCAAATGCGGAACAACTTGAGGCCCATTCGAAGGAACATAATCGTCGACTTGCTGCAATGAATCGTAAAACTTACAACACAAGTATCCAAATGCATGACCCGATTGTGATTAATCAGGAAATAAAACACGCAGATACCCGGAGGCGTTTATATAAATGTAACGATTGTCCAAAGAGTTTCATAAAATTGTGCCACCTTAAGCAGCATCAACTATCGCATACGGGCGACCGACCGTTCAGTTGtgataaatgtataaaaacatttaaatctcGGAATGCCTTGACCATCCATACCCGAGGCCATTCAAATCTAAAGCCATACAAATGCGAGACGTGCAATGAACATTTTGTATCAAGGCCAATTTTGAAGCGACACAGCTTGATCCATTCCGAGGTGCGCAATTTTATATGCCCttattgtcaaaaatcgtttaaatccAATTCAGATTGCCGCAAACATATTCGAATACATCAAAAGGAAATTGTCACCCCTCCGGTTGAGCTCGATGTGTGCCCTAGCGCACATGTAGTATGTATTAATCAAATACAACCAAGCTTCAAGACCTGTCAATACTGCAatcgttattttaaaaaaccaatCGACCTTCGACGGCACGAAAGGGTACATACCGGCGAACGACCATTTAATTGTGATAAATGCGATAAATCGTTTTCCTTGGCGTCCACTTTGAAATTCCATCAAAGAATTCATGATGAATTCAAGCGAATGTTCACGTGTCACGTTTGTTCTAATAAATACGCTACAAAGGGTAGCCTTAAAGTGCATAAACGAATCCACACTGGCGAAAAACCATTTAAATGCAGATTCTGTGACgtaaaatttaggacaaatggACATCGCAGCGTTCATGAATCAAATCACTTAAAAATCGCTTGCGAACGTGGCATAGACCCTAAAGATGTTAAAAATATGCGATCATCGAAATTCGAGAGTATTGTCGAAGATTTCACGTTTAATTAA
Protein Sequence
MDSQLYILFNNNVLTPIDQSNICYVIESGLLVPISNDINSINPVEEPFVTSEEFICNYDEQIIPINEEEFSTSGLSMPIDDGFNEIFMEYNEAESTRLPNELYINSTSDPSNTKNSYGCEHCGIKFLQIKLLNRHKMTHIYEKPFKCNQCHESFNFSVNLKVHNTFHQDPLVNSGRPRHVCSVCNKIFRRFSSLRGHLKGHSVSDYFNCDHCNEIFLAKSFYENHLDNYHKKEDKERKTVKLPSGGNVANIGRDCKLCGKSFKKPSMLVRHMRVHNGDKPFNCGTCGRQFSQKNSLKIHLLRHTGRKPFACTLCSMRFTQKGNLKIHKEKVHNKFSSNTEATKYPCNKCSCVFRKIGSLNRHITEVHSASNRKGTTSNGEINFNEIMSQINDLKQAPPIPETSEQQGDDIIQLADRLENGILIHRKVQHLSTHRGKNMLSCLNCGKLFTRPSDLLRHIRVHTKEKPYECYLCKRRFSVQRTLSLHYKTHESALRKFSCSVCSKNFRDVATLLVHGTEYHQNSSDYLQCFRCKLIFSNAEQLEAHSKEHNRRLAAMNRKTYNTSIQMHDPIVINQEIKHADTRRRLYKCNDCPKSFIKLCHLKQHQLSHTGDRPFSCDKCIKTFKSRNALTIHTRGHSNLKPYKCETCNEHFVSRPILKRHSLIHSEVRNFICPYCQKSFKSNSDCRKHIRIHQKEIVTPPVELDVCPSAHVVCINQIQPSFKTCQYCNRYFKKPIDLRRHERVHTGERPFNCDKCDKSFSLASTLKFHQRIHDEFKRMFTCHVCSNKYATKGSLKVHKRIHTGEKPFKCRFCDVKFRTNGHRSVHESNHLKIACERGIDPKDVKNMRSSKFESIVEDFTFN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01052485;
90% Identity
iTF_01053657;
80% Identity
-