Basic Information

Insect: Nephrotoma flavescens
Gene Symbol: zfy1
Assembly: GCA_932525705.1
Location: CAKOBH010004354.1:9661-12311[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 20 0.00014 0.025 16.7 2.8 1 23 116 138 116 138 0.98

2 20 0.002 0.37 13.1 4.3 1 23 144 166 144 166 0.91

3 20 0.0023 0.42 12.9 5.0 1 23 178 200 178 200 0.96

4 20 8.5 1.5e+03 1.7 0.6 1 21 206 226 206 229 0.75

5 20 1.3e-07 2.4e-05 26.2 0.8 3 23 254 274 253 274 0.98

6 20 5.3e-06 0.00095 21.2 2.3 1 23 280 302 280 302 0.98

7 20 0.00013 0.024 16.8 0.9 1 23 308 331 308 331 0.95

8 20 0.00066 0.12 14.6 1.3 1 23 343 366 343 366 0.94

9 20 1.3e-06 0.00023 23.1 0.3 2 23 439 460 438 460 0.96

10 20 0.00082 0.15 14.3 3.0 1 23 466 488 466 488 0.99

11 20 0.058 10 8.5 0.1 1 22 495 516 495 518 0.89

12 20 0.0035 0.63 12.3 0.4 2 23 526 547 525 547 0.95

13 20 0.017 3.1 10.2 9.4 1 23 584 606 584 606 0.98

14 20 0.00038 0.068 15.4 0.7 1 23 612 634 612 634 0.97

15 20 3.4e-05 0.0061 18.7 1.6 1 23 640 662 640 662 0.97

16 20 1.6e-05 0.0029 19.7 2.7 1 23 668 690 668 690 0.98

17 20 0.00019 0.034 16.3 1.8 2 23 720 741 719 741 0.97

18 20 0.00011 0.02 17.1 1.7 1 23 747 769 747 769 0.97

19 20 0.0005 0.09 15.0 2.6 1 23 776 798 776 798 0.98

20 20 0.15 26 7.2 3.8 1 23 804 826 804 826 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	20	0.00014	0.025	16.7	2.8	1	23	116	138	116	138	0.98
2	20	0.002	0.37	13.1	4.3	1	23	144	166	144	166	0.91
3	20	0.0023	0.42	12.9	5.0	1	23	178	200	178	200	0.96
4	20	8.5	1.5e+03	1.7	0.6	1	21	206	226	206	229	0.75
5	20	1.3e-07	2.4e-05	26.2	0.8	3	23	254	274	253	274	0.98
6	20	5.3e-06	0.00095	21.2	2.3	1	23	280	302	280	302	0.98
7	20	0.00013	0.024	16.8	0.9	1	23	308	331	308	331	0.95
8	20	0.00066	0.12	14.6	1.3	1	23	343	366	343	366	0.94
9	20	1.3e-06	0.00023	23.1	0.3	2	23	439	460	438	460	0.96
10	20	0.00082	0.15	14.3	3.0	1	23	466	488	466	488	0.99
11	20	0.058	10	8.5	0.1	1	22	495	516	495	518	0.89
12	20	0.0035	0.63	12.3	0.4	2	23	526	547	525	547	0.95
13	20	0.017	3.1	10.2	9.4	1	23	584	606	584	606	0.98
14	20	0.00038	0.068	15.4	0.7	1	23	612	634	612	634	0.97
15	20	3.4e-05	0.0061	18.7	1.6	1	23	640	662	640	662	0.97
16	20	1.6e-05	0.0029	19.7	2.7	1	23	668	690	668	690	0.98
17	20	0.00019	0.034	16.3	1.8	2	23	720	741	719	741	0.97
18	20	0.00011	0.02	17.1	1.7	1	23	747	769	747	769	0.97
19	20	0.0005	0.09	15.0	2.6	1	23	776	798	776	798	0.98
20	20	0.15	26	7.2	3.8	1	23	804	826	804	826	0.95

Sequence Information

Coding Sequence: ATGGATTCACAATTATACATTTTATTTAATAATAACGTACTAACACCAGATCAATCGAATATATGTTATGTAATTGCCTCCGGACTGCTAGTGCCAATATCCAATGACATAAATTCTATAAACCCCGTTGAAGAACCTTTCGTAAATTCCGAGGAGCTTACTTGCAATTATGATGAACAAATAATACCAATCAACGAAGAGGAATTCAGTACTTCCGGTTTATCAATACAAATTGATGATGAATTTAACGAGATCTTCATGGAATGTAATGAGGCCGAAAGTACTAGGCTTCCAAACGAACCATATATAAATCCAACATCTGACCCACCAAATATTGAAAACTCGTATGCGTGTGAACACTGTGGAATCAAATTTCCACACATAAAACTGTTGAATCGGCACAAGATGACACATATTTACGAGAAACCATTTAAATGCAACCAATGCCATGAGAGTTTTAATTTTTCGGTCAATTTAAAGGTGCACAATACATTCCATCAAGATCCATTGGTCAATTCTGGCAGACCAAAACATATGTGCTGTGTTTGTAACAAAATATTCCGCCGTTTTTCAAGCTTACGTGGGCACCTCAAAGGGCATTTGGTCTCGGATTATTTTAATTGCGATCTTTGCAATGAAATATTTTTGGCAAAAACATTTTATGAAAATCATTTGGATAATTACCATAAAAAGGAAGACAAGGAAAGTAAAATCGTTAAATTATCTAGTGGTGGTAACGTTGCCAACATTGAACGAGACTGTAAATTATGTGGCAAATCATTTAAAAAACCCAGTATGCTGGTTCGCCATATGCGAGTGCATAATGGTGACAAACCATTTAAATGCGGTACATGCGGTAGGCAATTTTCTCAAAAAAATTCCCTCAAAACACATTTGCTTCGACACACAGGAAGAAAACCTTTCGCTTGTACGTTGTGTTCTATGCGATTCACACAGAAAGGCAATCTAAAGATCCACAAGGAAAAAGTTCATAACAAATTCAGCTCAAATATGGAGGACACGAAATATCCCTGCAATAAATGCTCATGCGTATTTCGTAAAATCGGTTCACTCAATCGGCATATCACGGAAGTCCATAGCGCGAATAATCGGAAAGGGGTGACGTCTAATAGAGAAATTAATTTCAACGAGATTATTTCACAAATCAACGATCTAAAACAAGCACCCTCTACTCCTGAAACTTCGGAACAACAAGGTGATGGTATTATTCAGTTAGCCGATCGACTAGAAAACGGTATTTTAATTCATCGTAAAGTACAACATTTGGGCACCGACCGGGGTAAAAATATGTTAAGTTGCCTAAACTGTGGAAAACTTTTTACTCGACCATCGGACTTGCTACGACACATTCGTGTGCACACGAAGGAGAAGCCGTATGAATGCTATCTATGCAAACGTCGTTTTTCCGTCCAGAGGACTCTCTCACTTCACTATAAAACACATGAAAGCGCTTTGCGCAAATTCTCTTGTAGTGCCTGCAGTAAAAACTTTCGTGATATTGCCACCCTGTTAGCGCACGGGATTGAATACCATCAAAATTCTTGTGACTACTTGCAATGTTTTCGGTGCAAATTGATTTTCTCAAATGCGGATCAACTTGAGGTCCATTCGAAGGAACATAATCGTCGACTTGCAATGAATCGTAAATCTTACAACACAAGTATCCAAATGCAGGATCCGATTGTGATTAATCATGAAATAAAACAAGCAGATACCCGGAGACGGTTACATAAATGTTACGACTGTTCAAAGAGGTTCATAAAATTGTGCCACCTTAAGCAGCACCAGCTATCGCATACGGGTGACCGACCATTCAGTTGTGATGAATGTATAAAAACATTTAAATCTCGGAATGCCCTGACCATCCATACCCGAGGCCATTCAAATCTAAAGCCATACAAATGCGAGACGTGCGATGAACATTTTGTATCAAGGCCTAATTTGAAGCGGCACAGCTTGATTCATTCCGAGGTACGCAATTTTATATGCCCTTATTGTCAGAAACCGTTTAAATCCAATTCAGATTGCCGCAAACATATTCGAATACATCAAAAAGAAATTGTCGCGCCTCCGGTTGAGCTCGATGTGTGCCCTAACGCACATGTATGCATTAGCCAAATACAACCCAGCTTCAAGACATGTCGATACTGTAATCGTTATTTCAAAAAACCAATCGACCTTCGACGGCACGAAAGGATACATACCGGCGAACGACCGTTTAATTGTGATAAATGCGATAAATCGTTTTCCTTGGCCTCCACTTTGAAGTTTCATCAAAGAATTCATGATGAATTCAAGCGAATGTTCACGTGCCACGTATGTTCTAATAAATACGCCACAAAGGGTAGCCTTAAAGTGCATAAGCGAATTCACACCGGCGAGAAGCCATTTAAATGCAGATTCTGTGACGTAAAATTTAGGACAAACGGACATCGAAGCATTCATGAATCAAATCACATAAAAATCGCTTATGAACGTGGCATAGACCCTAAAGATGTTAAAAATATGCGATCGTCGAAATTCGAGAGTATCGTTGAAGATTTTACGTTTAATTAA
Protein Sequence: MDSQLYILFNNNVLTPDQSNICYVIASGLLVPISNDINSINPVEEPFVNSEELTCNYDEQIIPINEEEFSTSGLSIQIDDEFNEIFMECNEAESTRLPNEPYINPTSDPPNIENSYACEHCGIKFPHIKLLNRHKMTHIYEKPFKCNQCHESFNFSVNLKVHNTFHQDPLVNSGRPKHMCCVCNKIFRRFSSLRGHLKGHLVSDYFNCDLCNEIFLAKTFYENHLDNYHKKEDKESKIVKLSSGGNVANIERDCKLCGKSFKKPSMLVRHMRVHNGDKPFKCGTCGRQFSQKNSLKTHLLRHTGRKPFACTLCSMRFTQKGNLKIHKEKVHNKFSSNMEDTKYPCNKCSCVFRKIGSLNRHITEVHSANNRKGVTSNREINFNEIISQINDLKQAPSTPETSEQQGDGIIQLADRLENGILIHRKVQHLGTDRGKNMLSCLNCGKLFTRPSDLLRHIRVHTKEKPYECYLCKRRFSVQRTLSLHYKTHESALRKFSCSACSKNFRDIATLLAHGIEYHQNSCDYLQCFRCKLIFSNADQLEVHSKEHNRRLAMNRKSYNTSIQMQDPIVINHEIKQADTRRRLHKCYDCSKRFIKLCHLKQHQLSHTGDRPFSCDECIKTFKSRNALTIHTRGHSNLKPYKCETCDEHFVSRPNLKRHSLIHSEVRNFICPYCQKPFKSNSDCRKHIRIHQKEIVAPPVELDVCPNAHVCISQIQPSFKTCRYCNRYFKKPIDLRRHERIHTGERPFNCDKCDKSFSLASTLKFHQRIHDEFKRMFTCHVCSNKYATKGSLKVHKRIHTGEKPFKCRFCDVKFRTNGHRSIHESNHIKIAYERGIDPKDVKNMRSSKFESIVEDFTFN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01052485;
90% Identity: iTF_01053656; iTF_01052485; iTF_01054580;
80% Identity: iTF_01053656;