Basic Information

Insect: Nephrotoma appendiculata
Gene Symbol: -
Assembly: GCA_947310385.1
Location: OX371224.1:124603807-124605654[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 8.8e-06 0.002 20.6 0.3 1 23 46 71 46 71 0.96

2 15 0.27 59 6.5 0.9 1 23 77 100 77 100 0.94

3 15 0.00015 0.032 16.8 0.1 1 23 119 141 119 141 0.96

4 15 2.1e-05 0.0045 19.4 0.5 1 23 148 170 148 170 0.96

5 15 0.012 2.7 10.7 0.3 1 21 176 196 176 197 0.94

6 15 5.1e-06 0.0011 21.3 1.5 1 23 229 251 229 251 0.98

7 15 0.00021 0.046 16.3 1.2 1 23 257 279 257 279 0.98

8 15 3.5 7.8e+02 2.9 0.4 2 19 285 302 284 307 0.77

9 15 1.4 3.1e+02 4.2 3.7 1 23 313 335 313 335 0.95

10 15 8e-05 0.018 17.6 2.9 1 23 345 367 345 367 0.98

11 15 3.2e-05 0.0072 18.8 3.6 1 23 391 414 391 414 0.91

12 15 0.16 35 7.2 0.8 1 23 419 443 419 443 0.94

13 15 1.8e-05 0.0039 19.6 1.0 1 23 459 483 459 483 0.98

14 15 0.0029 0.64 12.7 1.3 1 21 488 508 488 509 0.94

15 15 0.094 21 7.9 0.3 2 21 522 541 521 542 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	8.8e-06	0.002	20.6	0.3	1	23	46	71	46	71	0.96
2	15	0.27	59	6.5	0.9	1	23	77	100	77	100	0.94
3	15	0.00015	0.032	16.8	0.1	1	23	119	141	119	141	0.96
4	15	2.1e-05	0.0045	19.4	0.5	1	23	148	170	148	170	0.96
5	15	0.012	2.7	10.7	0.3	1	21	176	196	176	197	0.94
6	15	5.1e-06	0.0011	21.3	1.5	1	23	229	251	229	251	0.98
7	15	0.00021	0.046	16.3	1.2	1	23	257	279	257	279	0.98
8	15	3.5	7.8e+02	2.9	0.4	2	19	285	302	284	307	0.77
9	15	1.4	3.1e+02	4.2	3.7	1	23	313	335	313	335	0.95
10	15	8e-05	0.018	17.6	2.9	1	23	345	367	345	367	0.98
11	15	3.2e-05	0.0072	18.8	3.6	1	23	391	414	391	414	0.91
12	15	0.16	35	7.2	0.8	1	23	419	443	419	443	0.94
13	15	1.8e-05	0.0039	19.6	1.0	1	23	459	483	459	483	0.98
14	15	0.0029	0.64	12.7	1.3	1	21	488	508	488	509	0.94
15	15	0.094	21	7.9	0.3	2	21	522	541	521	542	0.94

Sequence Information

Coding Sequence: ATGAACCATTTTAGCCTTGTTACACTAAATCAATCCGAATCCGCAGAAGTCCCGAGTGGTAGCAATTATCCGAAAATGGACTTAAATACAGCCACAAAATCGAAGCCAAATAAAAATAAAATATCTAAACATCAATATGAGTGTAGAATCGAGGGCTGCGATAAATCATTCACCAGTGCTTCGGCTGTCAACAATCACATGAAACGAAAACATTTGGCTAAAAGTTTCTATCCGTGTGATGAGTGTTCAGTAAACTTTACCATTCAACATGAGCGAACCTTACACAAAATAAAAGAGCACGAAGGGAGGCGTTTCCAAATATCACGATTCCAAACAAAAAAAGACAATTCCGAATATCCATGTCCTGAGTGCAGTAAAGTATTTTACACGCTCGACATGTTTGCCGAGCATCGCATTTTACACGATTCCACGATTATCAAGTACACGTGCAAGGATTGTGGCAAGGAATTTATATCGGAGAAAAAATTAAAAGATCATTCAATCGTACACCAAGAACGAACCATGTATAAATGTAACGTTTGCGCAAAAGTATTCCTTCGTAGCCAAACGCTTCAATATCATCGATTAATTTGTAAAGCCGCATATCCATGTGATGAGTGTGTCGATAGTTTAATGACCGAAGCAGCTCTGGTTAAGCACAAAGTATTCCATGCGGCTGCCAATTTCACATGCAAGAAATGTAATAAAGTGTTTCCAAATCAGGAAACACTTTCGGTGCACGAGAAACGTCATTCACTTCGTATGAACTACACTTGCCAAATATGCAAGGAGACGATATCGACCCAAGCCAAATTTCAAAAACATATCAAGGATCATTTGGAAATGAATCTTGAATGTCGAATTTGTAAGGAAAAATTTCAGAGTCTCGTCAAATATGGATACCACAAAGCGGAGATGCACTCAATTATGCGACCATACGATTGTGTTTTGTGCAGTGATGAATTTTGCACGAGAACCGACCTTTTTCTTCATTTGCATAATCATATTGATATGAATACATCCACAAATATGTATCAATGCGAACATTGCGATATAAAATTTTCGCTCAAAGAAAATTACGAGAAACATCGCGATTCACATCGCAAAGATGAACTTGTTGTTTCACCACCGCCGCTAATTCTGCAACCATTAGAAGAGGAAACTTCTAATTTTGAGTGTGATCATTGTGATAAAAGCTTTAACTATAAATCTCTATTATCACATCACAAAATCGCTGAGCATGAATCGCGTGTTTATCCGTGTACAATAGGATTTTGTGATCAAAAATTTAGCACGCTTGCAGATTGTACAGAGCACCAGGCGCAACATGAAACTGACCCGAATTTAGAAGACGGATCACAGGATACGCTACCTTTTAAATGTAATATAGAAGGTTGTAAACGTTCGTTTGAATACGCGAGCCGTTTAAACAAGCATATGATGTCACACGTCCTTAATGAGTATAAATGCACGAAGTGCGATCGAATTTTCTATTCGCAGTCCATATTCCAGCAACATTACAATGTGTGTGAAAGTAGCAACAGTAATCATTTTGGTCCGGTTAAATGTAGTATTTGTCGCCAACTGTTTGAAAATCCGACTGTGTTGCAGAATCATCGAAAATTTTGTTGGGAAAATAGCAGCACGTTGAGCGAGGATAAAAGCGTCTTCTCGAATAACGATAGCGTTCAGAGTTTTCGTTCGATTGATAATTTACGTAGTCCGGAAAGTATTTTATCGGTGTATGTACAAAATGATTATGATTCAAATTTGCTTCCGGAATTTTAG
Protein Sequence: MNHFSLVTLNQSESAEVPSGSNYPKMDLNTATKSKPNKNKISKHQYECRIEGCDKSFTSASAVNNHMKRKHLAKSFYPCDECSVNFTIQHERTLHKIKEHEGRRFQISRFQTKKDNSEYPCPECSKVFYTLDMFAEHRILHDSTIIKYTCKDCGKEFISEKKLKDHSIVHQERTMYKCNVCAKVFLRSQTLQYHRLICKAAYPCDECVDSLMTEAALVKHKVFHAAANFTCKKCNKVFPNQETLSVHEKRHSLRMNYTCQICKETISTQAKFQKHIKDHLEMNLECRICKEKFQSLVKYGYHKAEMHSIMRPYDCVLCSDEFCTRTDLFLHLHNHIDMNTSTNMYQCEHCDIKFSLKENYEKHRDSHRKDELVVSPPPLILQPLEEETSNFECDHCDKSFNYKSLLSHHKIAEHESRVYPCTIGFCDQKFSTLADCTEHQAQHETDPNLEDGSQDTLPFKCNIEGCKRSFEYASRLNKHMMSHVLNEYKCTKCDRIFYSQSIFQQHYNVCESSNSNHFGPVKCSICRQLFENPTVLQNHRKFCWENSSTLSEDKSVFSNNDSVQSFRSIDNLRSPESILSVYVQNDYDSNLLPEF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01455131;
90% Identity: iTF_01054622;
80% Identity: -