Basic Information

Insect: Nebria salina
Gene Symbol: znf423
Assembly: GCA_944039265.1
Location: CALUEJ010000326.1:94891-105137[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 21 2.4e-05 0.0023 19.1 1.1 1 23 86 108 86 108 0.98

2 21 0.3 29 6.2 5.9 1 23 114 136 114 136 0.98

3 21 1.6e-06 0.00016 22.8 4.1 1 23 142 164 142 164 0.99

4 21 2.6e-05 0.0025 19.0 0.2 1 23 170 192 170 192 0.98

5 21 0.0022 0.21 13.0 0.2 2 23 227 249 226 249 0.95

6 21 0.085 8.3 8.0 2.6 1 23 348 371 348 371 0.96

7 21 1.8 1.7e+02 3.8 0.0 2 23 390 412 389 412 0.94

8 21 0.064 6.2 8.3 0.1 2 23 473 494 472 494 0.96

9 21 0.29 28 6.3 2.8 2 23 528 549 527 549 0.91

10 21 0.0011 0.1 13.9 0.5 1 23 557 580 557 580 0.94

11 21 0.019 1.9 10.0 0.3 1 23 585 608 585 608 0.92

12 21 0.0027 0.26 12.7 0.4 1 23 683 706 683 706 0.98

13 21 3.3 3.2e+02 3.0 0.6 3 23 768 790 766 791 0.86

14 21 0.0052 0.5 11.8 4.6 2 23 804 825 803 825 0.96

15 21 0.02 1.9 10.0 0.7 1 23 835 857 835 857 0.98

16 21 0.00064 0.062 14.6 0.6 1 23 974 997 974 997 0.95

17 21 0.17 17 7.0 0.6 1 23 1001 1023 1001 1023 0.96

18 21 0.0066 0.64 11.4 1.5 1 23 1031 1053 1031 1053 0.96

19 21 0.0043 0.42 12.0 0.6 1 23 1061 1083 1061 1083 0.97

20 21 0.041 4 8.9 1.0 1 23 1090 1112 1090 1112 0.96

21 21 0.0029 0.28 12.6 0.9 1 21 1163 1183 1163 1184 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	21	2.4e-05	0.0023	19.1	1.1	1	23	86	108	86	108	0.98
2	21	0.3	29	6.2	5.9	1	23	114	136	114	136	0.98
3	21	1.6e-06	0.00016	22.8	4.1	1	23	142	164	142	164	0.99
4	21	2.6e-05	0.0025	19.0	0.2	1	23	170	192	170	192	0.98
5	21	0.0022	0.21	13.0	0.2	2	23	227	249	226	249	0.95
6	21	0.085	8.3	8.0	2.6	1	23	348	371	348	371	0.96
7	21	1.8	1.7e+02	3.8	0.0	2	23	390	412	389	412	0.94
8	21	0.064	6.2	8.3	0.1	2	23	473	494	472	494	0.96
9	21	0.29	28	6.3	2.8	2	23	528	549	527	549	0.91
10	21	0.0011	0.1	13.9	0.5	1	23	557	580	557	580	0.94
11	21	0.019	1.9	10.0	0.3	1	23	585	608	585	608	0.92
12	21	0.0027	0.26	12.7	0.4	1	23	683	706	683	706	0.98
13	21	3.3	3.2e+02	3.0	0.6	3	23	768	790	766	791	0.86
14	21	0.0052	0.5	11.8	4.6	2	23	804	825	803	825	0.96
15	21	0.02	1.9	10.0	0.7	1	23	835	857	835	857	0.98
16	21	0.00064	0.062	14.6	0.6	1	23	974	997	974	997	0.95
17	21	0.17	17	7.0	0.6	1	23	1001	1023	1001	1023	0.96
18	21	0.0066	0.64	11.4	1.5	1	23	1031	1053	1031	1053	0.96
19	21	0.0043	0.42	12.0	0.6	1	23	1061	1083	1061	1083	0.97
20	21	0.041	4	8.9	1.0	1	23	1090	1112	1090	1112	0.96
21	21	0.0029	0.28	12.6	0.9	1	21	1163	1183	1163	1184	0.94

Sequence Information

Coding Sequence: atgttgtttaaGGGAAACAGTAGCAAACTTGAACTGTTAATTGAAAAAATACAATCCAACAAGGAGAATCACCTTAACACAGGCAACGGTCTAAAAGaagcACTGGGTACTGACCAAGGAAGCAGTTGGCGTTCGGAAACGCCAGAAGATCCTCAGACATCGCCGGCACCATCCTCCTGCGCCACGCCGAACTCAGCAACGGACCTGCCGGACGCAGAGCTTAGCTACACCGTGGGAATCACGGAAGCAACACCCTACGCCTGTCAGTTTTGCGATAAGGCATTCCCTCGACTAAGCTTCCTTAAGAAGCATGAACAGACGCATGGCGATCATATGCCGTTTCGGTGTGAATTCTGTTCAAGATTATTCAAACATAAACGCTCACGTGACAGACATATTAAACTACATACAGGAGacaaaaaatatagatgttcCCACTGCGAGGCTGCATTTTCCCGaagCGATCACTTGAAAATACATATGAAGACTCATGATACTCAAAAACCATTTCAATGTACAGTATGTAACAGAGGCTATAATACTGCCGCAGCATTAACATCTCATATGCAGAATCATAAACGACAAAGACCTGAAACACCATCAACAGGTAGACCAAGCAGCAGTGGTAGAAATACTGGTCAAGTCAGTGAAGAAAGCATCTCTAGTCCTAGTAGTTTACGATGTGTGCAATGTGGTGACACGTTTAGAAAACAGGAGCTATTGCAGagCCACATATTAAGTGTGCATAGTAGCGATGTTTCGCCTGATGTAACGATACGAACGACACCGGTACCTTTAGTCATCACAGATCCTAGAACAACACCACTCGGCACAAAATTAGCGTGTATATATTGTACAAAAGATAGTTTCACAACTATGGAACAACTACAACTGCACGTACAAGCAATGCATAGTACTATTTTGAATGGGGAACTTCGTGAATATACCCGAAAAATGGCTACACCTTCGCCGCAAAACCTAATGACTCCACCACCAGCTTTATCATCTGGCAATGGGCACACATCGAATTTTGGAGTTTCCTATCCATGCGATATGTGCACCATGCACTTTCCAACACTACAAAGATTACACAAGCATACAGTAACCGTCCATAGAAATTGCGATTCTACCGGTCAGACGGAATCCGTGTGTCAACAAAGTCCACTGGTATGTGTTCAGTGTGCTCTTCCATTTCAAACGTCCACAGCATTTGCTGAGCATTACCTTATGGTGCATGGTGGCAGCAGTCCATCATTCGCCATGTCCCCAATACCGGAACAAGTTAAACCGACAGATTTGAGCAGAAAAACACCCAGATCAGCATCAGAAGACAGAAAAGCCAAACGCTTATGTACAGATGACAATTCGACATGTACAGATACAACAGCTACTCATTATGAGTATCCGGGAATGTTGATATGTAACCAGTGTGATGCAGCCTTACCAGATTTTGAATCTTTCCGTACACATTTGAAATCGCATTTGGAACAAACCGGCGGaattcgaaatttattacaaaccGGAACCAGTGTGCTAGATTTGTTCTATCAAGAAAACATGAAACTACAATCGAATTCCTGTGTTTGTCCACACTGCGGAGCcaattttaaagatttagcCTCGTGTGACCAACACGTTATAACGCATTTCTTAGCAACTGCAACCGAGTATAGTTGCCAAAGTTGCATGAAAATGTTTTCGAAACCCGATGAATTACAAAAACACTTAATGGACATTCACGCTCACCATTTATACCGTTGCTCGATGTGTAAAGAAATGTTTGATTCGAAAGTAGCAATACAAGTACATTTCGCAGTAAAGCACAGTAATGAATGCAAACTGTTTAGATGTACAGCCTGCCCAAATGTTTCCTCGATATTTCATTCGGAAATTGAATTTAGTTTGCACGTACGTAGTGCGCATGGCGCGCATGCGCTCTTCTCAGCACTTCAGTCCCATACGAAGAGCTTACGTTGCATGTTTTGCCGCCAAACATTTGGCTCTGATTTGGAAATGCAGTTTCATCTAGCTACTCACTCCAAGCAATTCCGATGTCCAATTTGCCCAGAGGCGTTCCAAATTGAGTTTTTGTTGGATCGACACATACAAACTTGCCATAGCAATTCATCAAGGaTAAATGGTGAAACTGATTGCATTGATGGCGACAAGTCCAATAAAAAATCCTCGTCAAATTCACCGTTACAACTGGGGAAAATACTCACACCACCAAGAACTTCTGCGAAACCCTTAACAAGAGACAATAATAACGTGAAGAAACAGCATGATGTGTCTGAGACAAATTGTGAAATATGTGAACGCAATGATTTTACAAACGAAACCGAGTTAGTTGCACATCGAAAACTCGTGCATCATGTGcgtaataatagtaaaaatgGAGTTGTTAGCTTACATTGTGCTTATTGTAACGAAAACTGTAAGACTAGAACCGAGCTAGAAAACCACATGAAGAACCATTCGCAAAGTAGTGGTGTGTCTGGTAAgcataaatgtaatatttgtgATGAGTTGTGTCCTTCAGCTGTATTACTTGCTGAGCATAAATTAACACATTGTAAGGTAAGAACTGGGAACTGTTGCACGCAATGCAAAGGCAGTATTGCTAATGAAGAACAATTCTATTCACACCTTGTGCAGCAcagtaacaataataatggTGGTAACCAAAAGAGTAAATCTCAAGTTTCTCTGCCTTCTCCATGTATTATATGTCGACAGACTCTTATATCAGATATTGAAGCTAGAATTCATTCGCAATTTCATTTAAGAACCACGGTGCAGCTTGCAGATTTCCAATGTTCTATTTGCTTCAAAATCATAGATATTCAAAGTTTGATTATGTCCAAAGGCATTCATTTGTGTCCGGATTGTTTCACATTACCAACAGGTACACAACGAACATTCCACTGTGCTGAATGTCAACTTACGTTCGAAAATAGCTCAGCCCTCGAACAGCATACTGAATCAGTACACACGAAAACGTTCACATGCATAAAATGCCAGACTAGTTTTGATAGTGAACGTGACGTTCAGATACACGTCACCACTCATTTAATGAATGAAGGAAATAGTCACGAATGCCATTTATGCAGACGACTATTCGCCACGCCTATGAAACTGCAAGCACATTTGATTGAACACACATTTGCTGGATGTGGTGGTTTCACATGCTACTTATGTTCTGCCGTATTCACTGGCTCACACGGCTTACAAAGCCATATCCTCGAACACGGTCTCGCTGCAAGACCTTACGATTGTCCACAGTGCAACTTAAAGTTCTTCTTCCGCGCAGAATTAGACAATCATAGTTACACTCACTTAGGTCGTGGTTCAAGGTCATCTACCGATGAACTACCTGTCCTTAGTCCAAAAGCGTACTATGTATCTTCCATTTCGAAGTTTGACTCAAGCAAAAATGGTGATAAATATTCAATGAAAGAGAAGAAAGAGAAGAAGTCGTCCAATCTATTTAAATGTACAGTGTGCAATAAAGAATTCACTTACGGTACTGAGTTGCAGTTACATGTGCAGCATTGTACTGATACGCAAGCGTACCCGAAAGATGAAACAGTTGTTAAACAAGAACCAAAAGAAGATGTAAGTGATTGTAAAAAGGAGTTCAATATGGATGTGAGTTCACTTGCTGCGTCACCGAAATTCAAATGCGAAGATTCGAATTCTTTCGAAAATTTTGAGAAAACTGAatctcaaaaataa
Protein Sequence: MLFKGNSSKLELLIEKIQSNKENHLNTGNGLKEALGTDQGSSWRSETPEDPQTSPAPSSCATPNSATDLPDAELSYTVGITEATPYACQFCDKAFPRLSFLKKHEQTHGDHMPFRCEFCSRLFKHKRSRDRHIKLHTGDKKYRCSHCEAAFSRSDHLKIHMKTHDTQKPFQCTVCNRGYNTAAALTSHMQNHKRQRPETPSTGRPSSSGRNTGQVSEESISSPSSLRCVQCGDTFRKQELLQSHILSVHSSDVSPDVTIRTTPVPLVITDPRTTPLGTKLACIYCTKDSFTTMEQLQLHVQAMHSTILNGELREYTRKMATPSPQNLMTPPPALSSGNGHTSNFGVSYPCDMCTMHFPTLQRLHKHTVTVHRNCDSTGQTESVCQQSPLVCVQCALPFQTSTAFAEHYLMVHGGSSPSFAMSPIPEQVKPTDLSRKTPRSASEDRKAKRLCTDDNSTCTDTTATHYEYPGMLICNQCDAALPDFESFRTHLKSHLEQTGGIRNLLQTGTSVLDLFYQENMKLQSNSCVCPHCGANFKDLASCDQHVITHFLATATEYSCQSCMKMFSKPDELQKHLMDIHAHHLYRCSMCKEMFDSKVAIQVHFAVKHSNECKLFRCTACPNVSSIFHSEIEFSLHVRSAHGAHALFSALQSHTKSLRCMFCRQTFGSDLEMQFHLATHSKQFRCPICPEAFQIEFLLDRHIQTCHSNSSRINGETDCIDGDKSNKKSSSNSPLQLGKILTPPRTSAKPLTRDNNNVKKQHDVSETNCEICERNDFTNETELVAHRKLVHHVRNNSKNGVVSLHCAYCNENCKTRTELENHMKNHSQSSGVSGKHKCNICDELCPSAVLLAEHKLTHCKVRTGNCCTQCKGSIANEEQFYSHLVQHSNNNNGGNQKSKSQVSLPSPCIICRQTLISDIEARIHSQFHLRTTVQLADFQCSICFKIIDIQSLIMSKGIHLCPDCFTLPTGTQRTFHCAECQLTFENSSALEQHTESVHTKTFTCIKCQTSFDSERDVQIHVTTHLMNEGNSHECHLCRRLFATPMKLQAHLIEHTFAGCGGFTCYLCSAVFTGSHGLQSHILEHGLAARPYDCPQCNLKFFFRAELDNHSYTHLGRGSRSSTDELPVLSPKAYYVSSISKFDSSKNGDKYSMKEKKEKKSSNLFKCTVCNKEFTYGTELQLHVQHCTDTQAYPKDETVVKQEPKEDVSDCKKEFNMDVSSLAASPKFKCEDSNSFENFEKTESQK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01039572;
90% Identity: iTF_01040323; iTF_01039572;
80% Identity: -