Basic Information

Insect: Nebria ingens
Gene Symbol: znf423
Assembly: GCA_018344505.1
Location: JADQWA010000172.1:433377-441697[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 22 1.5e-05 0.0012 19.2 1.1 1 23 55 77 55 77 0.98

2 22 0.19 15 6.3 5.9 1 23 83 105 83 105 0.98

3 22 1e-06 8.1e-05 22.9 4.1 1 23 111 133 111 133 0.99

4 22 1.6e-05 0.0013 19.1 0.2 1 23 139 161 139 161 0.98

5 22 0.0014 0.11 13.0 0.2 2 23 197 219 196 219 0.95

6 22 9.7 7.8e+02 0.9 0.1 9 23 259 274 254 274 0.90

7 22 0.053 4.3 8.0 2.6 1 23 318 341 318 341 0.96

8 22 1.1 91 3.8 0.0 2 23 360 382 359 382 0.94

9 22 0.04 3.2 8.4 0.1 2 23 445 466 444 466 0.96

10 22 0.18 14 6.3 2.8 2 23 500 521 499 521 0.91

11 22 0.00067 0.055 14.0 0.5 1 23 529 552 529 552 0.94

12 22 0.012 0.97 10.0 0.3 1 23 557 580 557 580 0.92

13 22 0.0017 0.13 12.7 0.4 1 23 655 678 655 678 0.98

14 22 2 1.7e+02 3.0 0.6 3 23 740 762 738 763 0.86

15 22 0.0032 0.26 11.8 4.6 2 23 776 797 775 797 0.96

16 22 0.012 0.99 10.0 0.7 1 23 807 829 807 829 0.98

17 22 0.0004 0.032 14.7 0.6 1 23 947 970 947 970 0.95

18 22 0.11 8.7 7.0 0.6 1 23 974 996 974 996 0.96

19 22 0.0024 0.19 12.2 2.2 1 23 1004 1026 1004 1026 0.96

20 22 0.0027 0.22 12.1 0.6 1 23 1034 1056 1034 1056 0.97

21 22 0.026 2.1 9.0 1.0 1 23 1063 1085 1063 1085 0.96

22 22 0.0021 0.17 12.4 0.8 1 21 1136 1156 1136 1157 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	22	1.5e-05	0.0012	19.2	1.1	1	23	55	77	55	77	0.98
2	22	0.19	15	6.3	5.9	1	23	83	105	83	105	0.98
3	22	1e-06	8.1e-05	22.9	4.1	1	23	111	133	111	133	0.99
4	22	1.6e-05	0.0013	19.1	0.2	1	23	139	161	139	161	0.98
5	22	0.0014	0.11	13.0	0.2	2	23	197	219	196	219	0.95
6	22	9.7	7.8e+02	0.9	0.1	9	23	259	274	254	274	0.90
7	22	0.053	4.3	8.0	2.6	1	23	318	341	318	341	0.96
8	22	1.1	91	3.8	0.0	2	23	360	382	359	382	0.94
9	22	0.04	3.2	8.4	0.1	2	23	445	466	444	466	0.96
10	22	0.18	14	6.3	2.8	2	23	500	521	499	521	0.91
11	22	0.00067	0.055	14.0	0.5	1	23	529	552	529	552	0.94
12	22	0.012	0.97	10.0	0.3	1	23	557	580	557	580	0.92
13	22	0.0017	0.13	12.7	0.4	1	23	655	678	655	678	0.98
14	22	2	1.7e+02	3.0	0.6	3	23	740	762	738	763	0.86
15	22	0.0032	0.26	11.8	4.6	2	23	776	797	775	797	0.96
16	22	0.012	0.99	10.0	0.7	1	23	807	829	807	829	0.98
17	22	0.0004	0.032	14.7	0.6	1	23	947	970	947	970	0.95
18	22	0.11	8.7	7.0	0.6	1	23	974	996	974	996	0.96
19	22	0.0024	0.19	12.2	2.2	1	23	1004	1026	1004	1026	0.96
20	22	0.0027	0.22	12.1	0.6	1	23	1034	1056	1034	1056	0.97
21	22	0.026	2.1	9.0	1.0	1	23	1063	1085	1063	1085	0.96
22	22	0.0021	0.17	12.4	0.8	1	21	1136	1156	1136	1157	0.94

Sequence Information

Coding Sequence: ATGAAAGCACTGGGTACTGACCAAGGAAGCAGTTGGCGTTCGGAAACGCCAGAAGATCCCCAAACATCGCCGGCACCGTCCTCCTGCGCCACGCCGAACTCGGCCACGGACCTGCCGGACGCAGAGCTTAGCTACACCGTGGGAATCACGGAAGCAACACCCTACGCCTGTCAGTTTTGCGATAAGGCATTCCCTCGGCTAAGCTTCCTTAAGAAGCATGAACAGACGCATGGCGATCATATGCCGTTTCGGTGTGAATTCTGTTCAAGATTATTCAAACATAAACGGTCACGTGACAGACATATTAAACTACATACAGGAGACAAAAAATATAGATGTTCTCACTGCGAAGCTGCATTTTCCCGAAGCGATCACTTGAAAATACATATGAAGACGCACGACACTCAAAAACCATTTCAATGTACAGTATGTAACAGAGGCTATAATACTGCAGCAGCGTTAACTTCTCATATGCAAAATCATAAACGACAAAGACCTGAAACACCGTCAACGGGTAGACCAAGCAGCAGTGGTAGAAATACTACAGGTCAAGTCAGCGAAGAAAGTATCTCTAGTCCTAGTAGTTTACGATGTGTACAATGTGGTGACACATTTAGAAAACAGGAACTATTGCAGAGTCACATACTAAGTGTGCATACTACTGATGTTTCACCTGATGTAACGATACGAACTACACCGGTACCTTTAGTCATCACAGATCCTAGAACTACACCACTTGGCACAAAATTAGCGTGTATATATTGTACAAAAGATAGTTTCACAACTATGGAACAACTGCAACTACACGTACAAGCAATGCATAGTTCTATTTTGAATGGGGAGCTTCGTGAATATCCTCGAAAAATGGCTACACCTTCGCCTCAAAACCTAATGACTCCACCACCAGCTTTATCGTCTGGCAATGGGCACACATCGAATTTTGGAGTTTCGTATCCGTGCGATATGTGTACAATGCACTTTCCAACACTACAAAGATTACACAAGCATACAGTAACCGTCCATAGAAATTGCGATTCTACCGGTCAGACGGAGTCGGTGTGTCAACAAAGTCCACTGGTATGTGTTCAGTGTGCTCTTCCTTTTCAAACGTCCACAGCATTTGCCGAGCATTACCTCATGGTACATGGCGGCAGCAGTCCATCATTCGCCATGTCTCCACTTCCGGAACAAGTCAAGCCGACAGATTTGAGTAGAAAAACTTCAAGATCAGCATCAGAAGACAGAAAAACCAAACGGTTGTGTACAGATGACAACTCGACATGCACAGATACAACAACCACGGCGACCCATTACGAATATCCAGGAATGTTGATATGTAACCAATGTGATGCAGCCTTACCAGATTTTGAATCTTTCCGTACACACTTGAAATCGCATTTGGAACAAACTGGAGGAATTCGAAATTTATTACAAACCGGAACAAGTGTATTAGATTTGTTCTATCAAGAAAACATGAAACTACAATCCAATGCCTGTGTTTGCCCACACTGCGGAGCCAATTTCAAAGACTTAGCCTCTTGTGACCAACACGTTATAACGCATTTTCTAGCAACTGCAACCGAGTATAGTTGCCAAAGCTGCATGAAAATGTTTTCTAAACCCGATGAATTACAAAAACACTTAATGGACATTCACGCTCACCATTTATACCGTTGCTCTATGTGCAAAGAAATGTTTGATTCGAAAGTAGCAATACAAGTGCATTTTGCAGTAAAGCACAGTAATGAATGCAAACTGTTCAGATGTACAGCCTGCCCAAATGTATCCTCGATATTTCATTCGGAAATTGAATTTAGTTTGCACGTTCGAAGTGCGCATGGCGCCCATGCCCTGTTCTCAGCACTTCAGTCCCATACGAAGAGCTTACGTTGTATGTTTTGCCGCCAAACATTTGGCTCTGATTTAGAAATGCAGTTTCATCTAGCTACTCACTCGAAACAGTTCCGATGTCCAATTTGTCCCGAGGCGTTCCAAATAGAATTTCTGTTGGATCGACACATACAGACTTGCCATAGCAATTCATCAAGGATAAATGGTGACACCGACTGCATTGATGGAGACAAGTCCAATAAGAAATCCTCCTCAAATTCTCCGTTACAACTAGGGAAAATACTCACACCGCCAAGAACTTCTGCAAAGCCCTTAACAAGAGACAACAACAACGTGAAGAAACAGCATGACGTTTCGGAGACAAATTGTGAGATATGTGAACGCAACGATTTTACAAACGAAACCGAATTAGTTGCACATCGTAAACTCGTGCATCATGTGCGTAACAATAGTAAAAATGGAGTGGTTAGCTTGCACTGTGCTTACTGTAACGAAAACTGTAAGACTAGAACCGAGCTAGAAAACCACATGAAGAACCATTCGCAAAGTAGTGGTGTTTCTGGTAAGCATAAATGCAATATTTGTGATGAATTGTGTCCTTCAGCTGTATTACTTGCGGAGCATAAATTAACACATTGTAAGGTGAGAACGGGCAACTGTTGCACGCAATGTAAAGGCAGTATCGCTAATGAAGAACAATTCTATTCACATCTTGTGCAACACAGTAACAATAATAATGGTGGTAACCAAAAGAGTAAATCTCAAGTTTCTCTGCCTTCTCCATGCATTATATGTCGACAGACCCTTATATCGGATGTTGAAGCCAGAATTCATTCGCAGTTTCATTTAAGAACCACGGTGCAGCTGGCAGATTTCCAATGTTCTATTTGTTTCAAAATCATAGATATTCAAAGTTTGATTATGTCCAAAGGAATTCATTTGTGTCCGGATTGTTTTACATTACCAACAGGTACACAATTACGAACATTCCACTGTGCTGAATGTCAACTTACATTCGAAAATAGCTCAGCTCTAGAACAGCATACTGAATCTGTACACACTAAAACGTTCACATGTATAAAGTGTCAGACTAGTTTTGATAGTGAACGCGATGTTCAGATACACGTCACCACTCATTTAATGAATGAAGGAAATAGTCATGAATGTCATTTATGCAGACGACTATTTTCCACACCAATGAAACTGCAAGCACATTTGATTGAACACACATTTGCTGGCTGTGGTGGCTTCACTTGCTACTTATGTTCTGCAGTATTCACTGGCTCACATGGCTTACAAAGTCATATACTCGAACATGGTCTCGCTGCAAGACCGTACGATTGTCCACAGTGCAACTTAAAGTTCTTCTTCCGCGCAGAATTAGACAATCATAGTTACACTCACTTGGGGCGCGGTTCAAGGTCATCTGCAGATGAACTACCTGTTCTTAGTCCAAAAGCATATTATGTATCCTCCATTTCTAAGTTTGATACAAGCAAAAATGGTGATAAATATTCAATAAAAGAGAAGAAAGAGAAGAAGTCGTCCAATCTTTTTAAATGTTCAGTGTGCAATAAAGAATTCACTTACGGTACTGAGTTGCAGTTGCATGTGCAGCATTGTACTGACAACCAAGCGTACCCGAACAAAGATGAAACAATTGTTAAACAAGAACCAAAAGAAGAAGTAAATGACTGTAAAAAGGAGTTCAATTTGGAAGTGAGCTCACTTGCGGTTTCACCGAAATTCAAATGTGAAGATTCAAATTCTTTTGAAAATTTTGAGAAAGCCGAATCTCAAAAATAA
Protein Sequence: MKALGTDQGSSWRSETPEDPQTSPAPSSCATPNSATDLPDAELSYTVGITEATPYACQFCDKAFPRLSFLKKHEQTHGDHMPFRCEFCSRLFKHKRSRDRHIKLHTGDKKYRCSHCEAAFSRSDHLKIHMKTHDTQKPFQCTVCNRGYNTAAALTSHMQNHKRQRPETPSTGRPSSSGRNTTGQVSEESISSPSSLRCVQCGDTFRKQELLQSHILSVHTTDVSPDVTIRTTPVPLVITDPRTTPLGTKLACIYCTKDSFTTMEQLQLHVQAMHSSILNGELREYPRKMATPSPQNLMTPPPALSSGNGHTSNFGVSYPCDMCTMHFPTLQRLHKHTVTVHRNCDSTGQTESVCQQSPLVCVQCALPFQTSTAFAEHYLMVHGGSSPSFAMSPLPEQVKPTDLSRKTSRSASEDRKTKRLCTDDNSTCTDTTTTATHYEYPGMLICNQCDAALPDFESFRTHLKSHLEQTGGIRNLLQTGTSVLDLFYQENMKLQSNACVCPHCGANFKDLASCDQHVITHFLATATEYSCQSCMKMFSKPDELQKHLMDIHAHHLYRCSMCKEMFDSKVAIQVHFAVKHSNECKLFRCTACPNVSSIFHSEIEFSLHVRSAHGAHALFSALQSHTKSLRCMFCRQTFGSDLEMQFHLATHSKQFRCPICPEAFQIEFLLDRHIQTCHSNSSRINGDTDCIDGDKSNKKSSSNSPLQLGKILTPPRTSAKPLTRDNNNVKKQHDVSETNCEICERNDFTNETELVAHRKLVHHVRNNSKNGVVSLHCAYCNENCKTRTELENHMKNHSQSSGVSGKHKCNICDELCPSAVLLAEHKLTHCKVRTGNCCTQCKGSIANEEQFYSHLVQHSNNNNGGNQKSKSQVSLPSPCIICRQTLISDVEARIHSQFHLRTTVQLADFQCSICFKIIDIQSLIMSKGIHLCPDCFTLPTGTQLRTFHCAECQLTFENSSALEQHTESVHTKTFTCIKCQTSFDSERDVQIHVTTHLMNEGNSHECHLCRRLFSTPMKLQAHLIEHTFAGCGGFTCYLCSAVFTGSHGLQSHILEHGLAARPYDCPQCNLKFFFRAELDNHSYTHLGRGSRSSADELPVLSPKAYYVSSISKFDTSKNGDKYSIKEKKEKKSSNLFKCSVCNKEFTYGTELQLHVQHCTDNQAYPNKDETIVKQEPKEEVNDCKKEFNLEVSSLAVSPKFKCEDSNSFENFEKAESQK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01039572;
90% Identity: iTF_01041188;
80% Identity: -