Basic Information

Insect: Nebria ingens
Gene Symbol: prdm10
Assembly: GCA_018344505.1
Location: JADQWA010000209.1:759374-765674[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 7.1e-06 0.00057 20.2 0.6 2 23 581 602 580 602 0.97

2 13 0.021 1.7 9.2 5.2 3 23 627 647 626 647 0.97

3 13 0.085 6.9 7.3 0.3 2 23 678 699 677 699 0.95

4 13 0.0021 0.17 12.4 0.1 2 23 731 752 730 752 0.97

5 13 0.00019 0.015 15.7 0.8 1 23 770 792 770 792 0.98

6 13 0.036 2.9 8.5 3.1 2 23 801 822 800 822 0.97

7 13 0.00013 0.01 16.2 0.2 1 23 829 851 829 851 0.98

8 13 0.0038 0.31 11.6 2.9 1 23 857 880 857 880 0.95

9 13 3.8e-05 0.0031 17.9 0.3 3 23 887 907 886 907 0.99

10 13 1.2e-06 9.8e-05 22.6 2.4 1 23 913 936 913 936 0.95

11 13 0.0074 0.6 10.7 2.4 1 23 973 996 973 996 0.97

12 13 6.4e-05 0.0052 17.2 2.3 1 23 1018 1041 1018 1041 0.97

13 13 0.0024 0.2 12.2 2.6 3 23 1081 1102 1080 1102 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	7.1e-06	0.00057	20.2	0.6	2	23	581	602	580	602	0.97
2	13	0.021	1.7	9.2	5.2	3	23	627	647	626	647	0.97
3	13	0.085	6.9	7.3	0.3	2	23	678	699	677	699	0.95
4	13	0.0021	0.17	12.4	0.1	2	23	731	752	730	752	0.97
5	13	0.00019	0.015	15.7	0.8	1	23	770	792	770	792	0.98
6	13	0.036	2.9	8.5	3.1	2	23	801	822	800	822	0.97
7	13	0.00013	0.01	16.2	0.2	1	23	829	851	829	851	0.98
8	13	0.0038	0.31	11.6	2.9	1	23	857	880	857	880	0.95
9	13	3.8e-05	0.0031	17.9	0.3	3	23	887	907	886	907	0.99
10	13	1.2e-06	9.8e-05	22.6	2.4	1	23	913	936	913	936	0.95
11	13	0.0074	0.6	10.7	2.4	1	23	973	996	973	996	0.97
12	13	6.4e-05	0.0052	17.2	2.3	1	23	1018	1041	1018	1041	0.97
13	13	0.0024	0.2	12.2	2.6	3	23	1081	1102	1080	1102	0.98

Sequence Information

Coding Sequence: ATGGAAAACCCAACTGAATCAGTCCCCGATGAAGGAGAATTGTCCAACTTTCCTTCAAATGGAGCTTGGGCTCCACAGGGTTCAACAAATCCGAATTCTACGTTGCTGTTCATAGCTGTCGAATACGTAAAAGATGGCACAACTTCTGACTACAAATTTGAGTCAGAATCAAACTTTTCCCCTCAACCCTCCTCATACTCTGAGTTTGAGCAACATGTATCCCCCCTAGATCCAAATATGAGCTCAACCGCTCAATACTCTCCCGTTTATTCCCCATCAGCCGAAACGGCGTACAATAATTCAGTTGTTGTGCTCCAAGATTCCGTTAATCCTATTTTAACATCAGATATCGGTCAGAATTCAAATTCTTCTTTCATAAATTCGACAACCAATCCTCCCACATACCATTTAACAAATCCCGATTCTCCCCTCGACTCAATTGAGTCACCTCTATCAAATTCAGAGTCGCAATTATTGCGACAAGTTGCAACCAACCGATATTTACAAATGGTTACTACAAATGCTGATGAAGACGATCAAAATGTGCAAGAACGTAATATCAACATTGATTTCAACCAACGATCGGTCGAAGATGACGCCCAGATAATCGATAAAGAACTACAGTTGGTTCAATTTCCAATAAATACATATCACCATCAATTATCTATGGTTGATCGCGGTTTAAAAGTTGATCCAGATCATGTAGAATTACTGATAACAGATCAGAATACTGGGATATCTTATAGTGGTTATGTCTCCCAGGACTTTTTAGTGAGTCGTAGTGCTTTACCCGCTCTTCCAGAAGACGAACAGCAATTGAACACTGTTTTAAACACTTTAGAATCGCACGGATTAGTGATGGAATCAACAGATAATTCTGATATTCATCAAGTTAATGCACGTAGCACTTCCTTAGCAATCGCGGATGGACCTTTATTACTAGAAGATCCTCTACTTGATTCTAATCTATTACTTCAAGCACCTGTAGAAATATCTTTAGACGATTCCGTCTTAAATAACACAAATTCTTTAGTATTAAAACCAACTCCAACGAATAATCCAGTCATTCCCGGATTAAATCCGGCACCGATCAATATTGAAAATGATGTGAGTGATACAAAATTGAGTAAATACGATGTGAAAGAGGAACAGATGGAGTTTGAAGATGTTTATATAAAAAATGAGTTCGATGCTCAAAATTTGCGACGATCTCGACGGACGAACGACAAACAATGTTTCGATGATGATTTATCTGAAGTTCAAAGTATTTGCGATAAACCAGTGCCATCTCGAGCTAGAGCTACTTTACCAGCCAGTTATCTTGTAATCAACAAATTGGCATCGAATTCACCTGATTCCGACCCTGTGTATGGGGTTTTCGCTCGTAAAGCAATTCCGAAACGCACTCAATTCGGTCCTCTGGAAGGTGTACTCCTAGATACGCCACTTGATTCATCCGAAAACACAAGTTTAAAATTATTGTTAGAATCTGATTCGGGATCTATGCACCGCCTAGACATTTCAAATGAAAATACTTCGAATTGGATGAGATTTGTGAGACAAGCGCAACATTTCGGGGAACAAAATTTAATCTTGAGCCAACAAGGTTATTCGTTGTACTATACAACTACTAGAACCATTTTGCCCCGACAAGAACTCCAAGTCGGATATAGTGCTGTATATGCTACTAAACGTAAGTTAACAACTTTAGAACCTGCGGCTGAAGACGAAATGTCTTGGACTTGCTTTGAATGTCCACAGAAGTTTAACAGTTCGTCCGATTTACAGAAACACTTAAACGTCCATGATGAATCTAAGGGCGAGCAAATTAAACCACGAATCAAAAAGATAAATCGCTTTAAACGTAGACCAGTGGACTGTCCACATTGTACGCGTACATTTCTACGTCGGCACAGCTTAAGTCGTCACCTCCTTCAACATACAAACCCAAGCATATTTAGAGAGCGACAAATGCGACAAATACGTCGTCTTAACATTAGCACCGATCTAATTGATAAAAATCTGGAGTGGAAATGCGATATTTGTTGCTTATATTTTCCAAATCCATCTTTATTGAATTTGCACGAATTGGTACATAAAAATGAGCATGAGGAGACTATTACGGGTCTGCCCTTAGATTTGGGGTCTGGATGCAATGAGGGGGAGTTTTTGGTCCATAATGGAGCTGTGCAGTGTCCCCAATGTGGAATCGAATATCAAAGCCGTAAATTGTTAATAGAACATGTTTCGACACATGGACATAAACAAAATTCGCTTCTAACTTCAGAGGTTCCAGAGAAAAAAGGTTTTAAGTGTTATATGTGCTATAAAGCGTTCGCAGCTCGTGATCGGTTACAACGTCATATGTTAGTGCACGGTTCCGAAGACTCAAAACCGCTCAAATGTGACGTTTGCACTAAGCGATTTTTGAACAACAGCGCTTTACAGTGCCATTTAAAAACACATAAGTTAGATAAAAAGATCTTTGAATGTCCAATTTGTAAAATGACGTTCGAGCAAATTTTATCTTTAAAAGAACATGTCCGCATGCACTGCGTTGATGGTGTCTTCACTTGCCCCCATTGCAATAAGAATTTTAAAGAATACAGCATTATTCGCAAACATATTCGCGCGTTTCATTGCGATCGGAAACATGGTTGTCAGTATTGCGGCAAACCGTTTCCAACTTTGGACAAATTGCGCATGCATTTGCTCAAACATTCTGATCATCGCGAGTTTCTATGCTCAGAGTGTGGCAAACAGTTTAAGCGCAAAGACAAACTGAAAGAGCACATGAAACGAATGCACTCAGCCGATCGCGAACTAAGATTCGTTCAACCGAAAATTCTCAAAGGAAATTCGAACGCAAAGAAGTTTATGCCCAAGGTTCAACCAACTGATTATCACCGTTTTATCTATAAATGCCACAAATGCATGCTGGGTTTTAAACGAAGGGGCATGCTAGTGAATCATTTAGCCAAACGGCACCCGGATATAAGTCCGGATTCGGTACCAGAGTTGAATTTGCCGATTTTAAAAACTACACGAGATTATTACTGTCAATACTGCGATAAAGTTTACAAAAGCAGCTCAAAACGTAAAGCGCACATACTTAAAAACCATCCTGGTTTTGAGCTCCCAATGTCTAACCGACGTAAAGGAGGTATCCCTGATATACCCGGGTTGCCTAACCCGACCTTTTCTCAAACAGTGGGCAGCGTCACTACTAATCCACACGGCTGTCAGTGGTGCCACAAACAATACGCCTCCAAGGCAAAGTTACTCCAACATCAGCGCAAAAAGCATCAGGAATTGTTACCCAGTAACCAAAAAACCCCTAGAATTGGGAGTAAAGGCGTTTTAGGACCGGGACAACAGCCTCAATCACCAGGTGTACCAGAAGAGGGTAAATTTATGAATTCTCCCGATGTCCCTGACGGAACCAATGCTCTAACTGATGACAGTATCCAGACCATCACGGAAAATCAATTAGAAGTGTTAAACGCGAGTGGATACCTACAGTGTGAAGATACCAAACAGGGAATCGCTCAAATTGACTTGAAACAAACATTTAAGCTAACAGAGGAACCCCTAAACTTCGATGACTGTCGCCCAAGCGCCCAATATTATCGCCTAATACAAATGCCAACAAATCATTTACAATTGTCCCACAACCCCGACGACGAATCTATCGACGATCCTCCTGAATCTAGTCGTTTATACCGGCTCCTAACTTCTAACAATCAAAATGGCCCCTTTCCTCCGTATCCGCCACGTTGA
Protein Sequence: MENPTESVPDEGELSNFPSNGAWAPQGSTNPNSTLLFIAVEYVKDGTTSDYKFESESNFSPQPSSYSEFEQHVSPLDPNMSSTAQYSPVYSPSAETAYNNSVVVLQDSVNPILTSDIGQNSNSSFINSTTNPPTYHLTNPDSPLDSIESPLSNSESQLLRQVATNRYLQMVTTNADEDDQNVQERNINIDFNQRSVEDDAQIIDKELQLVQFPINTYHHQLSMVDRGLKVDPDHVELLITDQNTGISYSGYVSQDFLVSRSALPALPEDEQQLNTVLNTLESHGLVMESTDNSDIHQVNARSTSLAIADGPLLLEDPLLDSNLLLQAPVEISLDDSVLNNTNSLVLKPTPTNNPVIPGLNPAPINIENDVSDTKLSKYDVKEEQMEFEDVYIKNEFDAQNLRRSRRTNDKQCFDDDLSEVQSICDKPVPSRARATLPASYLVINKLASNSPDSDPVYGVFARKAIPKRTQFGPLEGVLLDTPLDSSENTSLKLLLESDSGSMHRLDISNENTSNWMRFVRQAQHFGEQNLILSQQGYSLYYTTTRTILPRQELQVGYSAVYATKRKLTTLEPAAEDEMSWTCFECPQKFNSSSDLQKHLNVHDESKGEQIKPRIKKINRFKRRPVDCPHCTRTFLRRHSLSRHLLQHTNPSIFRERQMRQIRRLNISTDLIDKNLEWKCDICCLYFPNPSLLNLHELVHKNEHEETITGLPLDLGSGCNEGEFLVHNGAVQCPQCGIEYQSRKLLIEHVSTHGHKQNSLLTSEVPEKKGFKCYMCYKAFAARDRLQRHMLVHGSEDSKPLKCDVCTKRFLNNSALQCHLKTHKLDKKIFECPICKMTFEQILSLKEHVRMHCVDGVFTCPHCNKNFKEYSIIRKHIRAFHCDRKHGCQYCGKPFPTLDKLRMHLLKHSDHREFLCSECGKQFKRKDKLKEHMKRMHSADRELRFVQPKILKGNSNAKKFMPKVQPTDYHRFIYKCHKCMLGFKRRGMLVNHLAKRHPDISPDSVPELNLPILKTTRDYYCQYCDKVYKSSSKRKAHILKNHPGFELPMSNRRKGGIPDIPGLPNPTFSQTVGSVTTNPHGCQWCHKQYASKAKLLQHQRKKHQELLPSNQKTPRIGSKGVLGPGQQPQSPGVPEEGKFMNSPDVPDGTNALTDDSIQTITENQLEVLNASGYLQCEDTKQGIAQIDLKQTFKLTEEPLNFDDCRPSAQYYRLIQMPTNHLQLSHNPDDESIDDPPESSRLYRLLTSNNQNGPFPPYPPR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00873319;
90% Identity: iTF_01041171;
80% Identity: -