Basic Information

Insect: Nebria brevicollis
Gene Symbol: prdm10
Assembly: GCA_944739395.1
Location: CALYJC010000014.1:55095-62083[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 1.2e-05 0.0011 20.1 0.6 2 23 580 601 579 601 0.97

2 13 0.037 3.4 9.2 5.2 3 23 626 646 625 646 0.97

3 13 0.15 14 7.3 0.3 2 23 707 728 706 728 0.95

4 13 0.0036 0.34 12.4 0.1 2 23 760 781 759 781 0.97

5 13 0.00033 0.03 15.7 0.8 1 23 799 821 799 821 0.98

6 13 0.062 5.8 8.5 3.1 2 23 830 851 829 851 0.97

7 13 0.00022 0.02 16.2 0.2 1 23 858 880 858 880 0.98

8 13 0.0065 0.61 11.6 2.9 1 23 886 909 886 909 0.95

9 13 6.6e-05 0.0061 17.8 0.3 3 23 916 936 915 936 0.99

10 13 2.1e-06 0.00019 22.6 2.4 1 23 942 965 942 965 0.95

11 13 0.013 1.2 10.6 2.4 1 23 1002 1025 1002 1025 0.97

12 13 0.00011 0.01 17.1 2.3 1 23 1047 1070 1047 1070 0.97

13 13 0.0041 0.39 12.2 2.6 3 23 1110 1131 1109 1131 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	1.2e-05	0.0011	20.1	0.6	2	23	580	601	579	601	0.97
2	13	0.037	3.4	9.2	5.2	3	23	626	646	625	646	0.97
3	13	0.15	14	7.3	0.3	2	23	707	728	706	728	0.95
4	13	0.0036	0.34	12.4	0.1	2	23	760	781	759	781	0.97
5	13	0.00033	0.03	15.7	0.8	1	23	799	821	799	821	0.98
6	13	0.062	5.8	8.5	3.1	2	23	830	851	829	851	0.97
7	13	0.00022	0.02	16.2	0.2	1	23	858	880	858	880	0.98
8	13	0.0065	0.61	11.6	2.9	1	23	886	909	886	909	0.95
9	13	6.6e-05	0.0061	17.8	0.3	3	23	916	936	915	936	0.99
10	13	2.1e-06	0.00019	22.6	2.4	1	23	942	965	942	965	0.95
11	13	0.013	1.2	10.6	2.4	1	23	1002	1025	1002	1025	0.97
12	13	0.00011	0.01	17.1	2.3	1	23	1047	1070	1047	1070	0.97
13	13	0.0041	0.39	12.2	2.6	3	23	1110	1131	1109	1131	0.98

Sequence Information

Coding Sequence: ATGGAAAATCCAGCTGAATCAGTCCCGGATGAAGGAGAATTGTCCAATTTTCCTTCAAATGGAGCCTGGGCTCCTCAGGGGTCGACAAATCCAAATTCTACATTGCTGTTCATAGCTGTCGAATACGTAAAAGATGGCGCAACATCTGACTACAAATTTGAGTCAGAATCAAACTTTTCCCCCCAACCCTCCTCATACTCTGAGTTTGAGCAACATGTATCCCCTTTAGATCCCAATATGAGCTCAACGGCTCAATACTCTCCCGTTTATTCCCCATCCGCCGAGACGGCGTACAATAATTCCGTTGTTGTGCTCCAAGATTCCGTCAATCCTATTTTAACATCAGATATCGGTCAGAATTCCAATTCCTCGTTCATAAACTCGACAACCAATCCGCCCACATACCATTTAACAAATCCCGACTCGCCCCTCGACTCAATCGAATCGCCGCTATCGAATACCGAATCGCAATTGTTGCGGCAAGTTGTCACCAACCGGTATCTGCAGATGGTTACCACCAATGTTGATGATGACGATCACAATGTGCAAGAACGTAATATCAACATTGATTTCAACCAACgTTCGGTGGAAGATGAGGCTCAGATAATCGATAAAGAACTACAATTGGTTCAATTTCCAATAAATACATATCACCATCAATTATCGATGGTTGATCGTGGTTTAAAAGTGGATCCCGATCACGTAGAACTATTGATCACCGATCAGAACACAGGAATATCTTATAGTGGCTATGTTTCCCAGGACTTTTTAGTGAGCCGTAACGCTTTACCTGCTCTTCCAGAAGACGAACAGCAATTGAACACTGTGTTAAATACTCTAGAATCGCACGGAATAGTCATGGAAACCACAAATAATTCTGATATCCATGATGTTAATGCACGTAACGCTTCTTTAGCTATCGCGGATGGACCTCTTTTACTAGAAGATCCTCTTCTTGATTCGAATCTATTGCTTCAAGcaCCTGTAGAAATATCTTTAGACGATTCAGTCTTAAATAGCACAAATACTTTAGTATTAAAACCGAATCCAACGAATAATCCAGTCGTTCCCGGATGCAATCCGGTTCCCATCgatattgtaaataatgtaactaaTACAAAATCGAGTAAATACGATGTAAAAGAAGAGCGAATGGAGTTTGAGGATGTGTATATCAAAAATGAGTTCGATGCCCAAAATTTACGACGATCGCGACGGACGAATGATAAGCAATGTTTCGATGATGATTtATGTGAAGTGCAAAGTATTTGCGATAAACCAGTGCCATCTCGCGCCAGGGCCACTTTACCAGCCAGTTATCTAGTAATCAACAAATTGGCATCGAATTCCCCTGATTCCGATCCTGAGTATGGTGTGTTTGCTCGTAAAGCAATCCCAAAACGGACTCAATTCGGCCCTTTAGAAGGTGTTCTCCTAGATACGCTTGATTCAACCGAAAGTctaagtttaaaattattattagaatctGAATCAGGCTCTATGCACCGTCTAGACATTTCAGAtgaaaATACATCGAATTGGATGAGATTTGTGCGACAAGCTCAAAATTTCGGGGAGCAAAATTTAGTCTTAAGCCAGCAAGGGTATTCATTGTATTATACAACTACTAGAACTATTTTACCCCGACAAGAACTCCAAGTCGGATATAGTACCGTATATGCAACTAAACGCAAGTTAACAACTTTAGAACCTGCGGCTGAAGACGAAATGTCTTGGACTTGCTTTGAATGTCCACAGAAGTTTAACAGTTCGTCCGATTTACAGAAACACTTAAATGTGCATGATGAAGCTAAGGAGGAGCAAATTAAACCACGAATCAAAAAGATAAATCGTTTTAAACGTAGACCGGTTGATTGTCCACATTGTACGCGTACATTTCTACGTCGGCACAGCTTAAGTCGCCACCTCCTTCAACATACAAATCCAACAATATTTAGGGAGCGGCAAATGCGACAAATACGCCGTCTTAACATTAGCACCGATCAAATCGaaaaatacaattatttattttacacacacacacttcgtataagaaaggaAAAACAGTGTATTTTGGTGCTAAttgaaggtttttttttaagtaaaaatCTGGAGTGGAAATGTgatatttgttgtttatatttcCCGAATCCATCGTTATTGAATTTGCACGAATTGGTGCATAAAAATGAGCATGAGGAGACAATTACGGGCCTGCCCTTAGATTTAGGGTCTGGTTGCAATGAGGGGGAGTTTTTGGTCCATAATGGAGCTGTACAGTGTCCCCAATGTGGAATTGAATACCAAAGTcgtaaattattaatagaacATGTTTCGACGCATGGACATAAACAAAATTCACTTCTAACATCTGAAGTTCCAGAGAAAAAAGGTTTTAAGTGTTATATGTGCTATAAAGCGTTCGCAGCTCGCGATCGTTTGCAGCGCCATATGTTGGTGCACGGTTCCGAAGACTCAAAACCGCTCAAATGCGATGTTTGCACTAAGCGCTTTTTGAACAACAGCGCTTTGCAGTGCCATTTAAAAACACATAAACTAGATAAAAAAATCTTCGAATGTCCCATTTGTAAAATGACGTTCGAGCAAATTTTATCGCTTAAAGAACATGTCCGAATGCACTGTGTAGATGGTGTCTTCACTTGCCCCCATTGCAAtaagaattttaaagaatatagtATTATTCGCAAACACATTCGCGCGTTCCATTGTGACCGAAAGCATGGTTGTCAGTATTGCGGTAAACCGTTTCCGACATTGGACAAATTGCGCATGCATTTGCTCAAACACTCGGATCACCGTGAGTTCTTGTGCTCGGAATGCGGAAAACAGTTTAAGCGCAAAGATAAATTGAAGGAGCACATGAAACGAATGCACTCTGGCGATCGTGAACTGAGATTCGTTCAGCCGAAAATCCTCAAAGGAAACACGAACGCAAAGAAGTTTATGCCCAAGGTTCAACCAACTGATTACCaccgttttatttataaatgccaTAAATGCATGTTGGGTTTTAAACGAAGGGGCATGCTAGTGAATCATTTAGCTAAACGGCACCCGGATATAAGTCCCGATTCGGTACCCGAGTTGAATTTACCGATTTTAAAAACAACTCGAGATTATTACTGTCAATACTGCGATAAAGTTTACAAAAGTAGCTCAAAACGCAAAGCGCACATACTCAAAAACCATCCAGGTTTTGAGCTCCCAATGTCTAACCGTCGCAAAGGTGGCATCCCAGATATACCGGGATTGCCTAATCCGACGTTTTCCCAAACAGTGGGCAGCGTCACTACTAATCCACACGGTTGCCAGTGGTGCCACAAACAGTACGCCTCCAAAGCGAAGTTACTGCAACATCAGCGCAAAAAACATCAGGAATTGTTGCCCAGCAACCAAAAAACTCCTAGAATTGGCAGTAAAGGCATTTTGGGACCGGAACAACAACCACAATCACCAGGTGTACCAGAAGAGGGAAAATTCATGAATTCTCCCGACGTACCCGACGGAACCAACGCTCTAACTGATGACACCATCCAAACCATCACGGAAAACCAATTGGAAGTGTTAAACGCGAATGGGTACCTACAGTGTGAAGATACCAAGCAAGGAATCGCACAAATTGACttgaaacaaacatttaagcTGACAGAAGAACCCCTAAACTTTGATGACTGTCGCCCAAGCGCCCAATATTATCGCCTGATACAAATGCCACCAAATCATTTACATTTGTCGCACAACCCCGACGACGAATCTATCGACGACCCCCCTGAATCGAGCCGTTTATACCGGCTGCTAACGTCTAACAATCAAAATGGCCCCTTTCCTCCATATCCACCACGTTGA
Protein Sequence: MENPAESVPDEGELSNFPSNGAWAPQGSTNPNSTLLFIAVEYVKDGATSDYKFESESNFSPQPSSYSEFEQHVSPLDPNMSSTAQYSPVYSPSAETAYNNSVVVLQDSVNPILTSDIGQNSNSSFINSTTNPPTYHLTNPDSPLDSIESPLSNTESQLLRQVVTNRYLQMVTTNVDDDDHNVQERNINIDFNQRSVEDEAQIIDKELQLVQFPINTYHHQLSMVDRGLKVDPDHVELLITDQNTGISYSGYVSQDFLVSRNALPALPEDEQQLNTVLNTLESHGIVMETTNNSDIHDVNARNASLAIADGPLLLEDPLLDSNLLLQAPVEISLDDSVLNSTNTLVLKPNPTNNPVVPGCNPVPIDIVNNVTNTKSSKYDVKEERMEFEDVYIKNEFDAQNLRRSRRTNDKQCFDDDLCEVQSICDKPVPSRARATLPASYLVINKLASNSPDSDPEYGVFARKAIPKRTQFGPLEGVLLDTLDSTESLSLKLLLESESGSMHRLDISDENTSNWMRFVRQAQNFGEQNLVLSQQGYSLYYTTTRTILPRQELQVGYSTVYATKRKLTTLEPAAEDEMSWTCFECPQKFNSSSDLQKHLNVHDEAKEEQIKPRIKKINRFKRRPVDCPHCTRTFLRRHSLSRHLLQHTNPTIFRERQMRQIRRLNISTDQIEKYNYLFYTHTLRIRKEKQCILVLIEGFFLSKNLEWKCDICCLYFPNPSLLNLHELVHKNEHEETITGLPLDLGSGCNEGEFLVHNGAVQCPQCGIEYQSRKLLIEHVSTHGHKQNSLLTSEVPEKKGFKCYMCYKAFAARDRLQRHMLVHGSEDSKPLKCDVCTKRFLNNSALQCHLKTHKLDKKIFECPICKMTFEQILSLKEHVRMHCVDGVFTCPHCNKNFKEYSIIRKHIRAFHCDRKHGCQYCGKPFPTLDKLRMHLLKHSDHREFLCSECGKQFKRKDKLKEHMKRMHSGDRELRFVQPKILKGNTNAKKFMPKVQPTDYHRFIYKCHKCMLGFKRRGMLVNHLAKRHPDISPDSVPELNLPILKTTRDYYCQYCDKVYKSSSKRKAHILKNHPGFELPMSNRRKGGIPDIPGLPNPTFSQTVGSVTTNPHGCQWCHKQYASKAKLLQHQRKKHQELLPSNQKTPRIGSKGILGPEQQPQSPGVPEEGKFMNSPDVPDGTNALTDDTIQTITENQLEVLNANGYLQCEDTKQGIAQIDLKQTFKLTEEPLNFDDCRPSAQYYRLIQMPPNHLHLSHNPDDESIDDPPESSRLYRLLTSNNQNGPFPPYPPR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00873319;
90% Identity: iTF_01041171;
80% Identity: -