Nbre004950.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Nebria brevicollis
Gene Symbol
RAP1GAP
Assembly
GCA_944739395.1
Location
CALYJC010000067.1:430007-447055[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 0.0002 0.092 13.8 0.0 7 43 595 634 590 647 0.88
2 2 7.7e-08 3.5e-05 24.8 0.0 51 108 769 826 759 828 0.89

Sequence Information

Coding Sequence
ATGATGTGTGAATTGACAAGTGATTGCATTGTTATGGATGTTACAGAACCATCTCCGTTGTACGACAACAACCATTACCACGAGGAATGCCTGCGGTGCAACTCGTGCGGCCTGAACTTAACGGGTCCGAATCAGAAGCGGGCGCGACGCTTCAAGAACCAGATTCTATGCGACTTGCACTTCGCTGACGTGGCCCTAATGGAGTGCAGCGACTTTATGCAGCAGCTGCGCTCGTTCAAGCCCCAATCACTAGGGTGTGCTGTCGCCCGCCGGAAATCTTCCACAACACTCATCTTTCCATTACCTCCGCAAGCGTGTTCAGACGAATTCTGCGAGGAATTCCCGCATAACCTAATCCCCACGCCTGGCTACTGGATAGAATGTTCCCGGCAGAAGATTACCTCGAACACGATATGGGACGAGAGTGAAGAAAGCGAACGTGACACAGGCTTACCAGAAGGTGATGAAGACGACGAGGCTACCGATGGCCACTCCGGTCACCATCATCTTCACCACCATGACAGAGGTTGCAACGATTTATATGAAGATGATGAGGACGATGATTCAATGTCGCCGAGGAAGAAGACCACAATTGAGGAACAATGGGAGAAAAACCAGGGATTCGAGTTGACAAGCGTTGAACAAGAAACGTACGAGAAGTACTTTTACGGCACTGAACACTGGAACTATTTCACAAACGATGAGGACCTCGGTCCGGTGATATTGTCAATAAAACAGGAAACACTCAATTCCAGAGATCAATTTAGAATATTAGTGCGAGCAATCAGTTATACGGTCCACGGTTTGATTCCCGCCAGTTGCGTGTTCGCTGATCGGTACAATCGAGAAGAGGTCGTAAGGTCACTTGGCAAAGAGGTCAATATTAACCCACCGTTGGTCTTGGGACAGTTGCCCGATACACCTGAAGAACTTTTGAAATTAGACCAAGTATTTATAAAATCTGAATTAAAGGTAGGAGTAATCTATGTAAAGGAAGGTCAATATACAGAAGAAGAAATCTTAGATAATAATGATAACTCGCCGTTGTTTGAAGAGTTTCTTCAGGTGCTTGGCGAAAAAGTACGTTTAAAAGgatttgataaatataaagGTGGCCTAGACACAGTCCACGACTTAACAGGGCTGTACTCAGTGTATACAAATTGGCGGAATATCGAAATTATGTTTCACGTTAGCACCCAATTACCATATGAGCGCCATGACCCTCAGAAGCTTCAAAGAAAACGACACATTGGAAACGATATTGTTTGTGTTGTGTTCTTAGAAGCAGACAATACTTCATTTTCACCTGCTTGCATCAAAAGTCATTTCCTACATACTTTTATACTCGttcGTACATCGCCTCGAATAAAGCGTAAACCAACACGATATGAAGTCTCAGTGGTGACGCGAGATGAAGTCGGTGCATACAAGCCTTATTTATGGGAACAAAGTGTTTTTGACAAAGGCACCATGTTCAGAGAGTggattttaacaaaaattgttaACGGCGAACGTGCTAGTTACTCAGCGCCAAAATTCGCACGTATGCAAGAACGCACGCGGTCACAAATGCTCGAAGATATCGTCGCGAATTTAGCGAACCACGCAGAAACTGGACAAATACCAAAACCATACCGAAGAGgtTCTTGGAGACCGATTGGGCATATGAGACCTTCCTCACCTTTACTGGACAGTGTTCGCGATCAATTTGAAGATTATGATCAATTAGCGAAAGATTTTACGAGGATGTTCTTGAATACGGAAGCAAATACATTGGCAAATGCCGCCCTATTTGATGTCGTATTCATGGTGGGCCAATCCAAacaaaagGTCAAATTCATTGGTGTGCGAGCAATTCTAGGGGTGAGGAGTCGTGTGTTTCAAGAAATGCTCTATGGAATACAAACTGGTTTTGGTTCACCACAAGTTCCAGTTGCTGAATTATTGGCGCGGCCTGCACCAACGCTAATGTCGCCTCAGCAATCACGCCCGAAaagtagtaattttttgcagGTTCCCGATATTGAGACACCACGTCCAAAAAGTGTTCCCAGTTCACCGATGGTGAAACGCGCCTTCTCACGCCTTGGAACAATTACAGCTGGCTGGGGTAGATCAATTCGTAAACAACACACTCACCTATCCGTTGATGATAAGAAGAAATGGTCATCTTCTCAAGATTGTTCAAATAAAGATGGGAAAGACAAAGACGGCAAGGATAAAAGTGCAATGCCTCAACTTGCAGTACCGCGGTTGTCCGTTTGCGCAGATGCGCAGAAAGTCGATCGTGCGAAGCTCGCACAAACCGAATTTTGCATCATAGAATTTGATCCCGAAACGTTTCGCATTCTATTGGATTACCTCCATACTGGCTCGTGCCCGCTAACATGTGCCTCAATACCAGGTCTTATATGTGCTGCCGAACATTATGATCTGCCAGAATTACTCCAAGCGTGTTTCCACCATGCCAAACAGTTTCTACGCATCGATGTTGTATGTGTCATGTTAGTTTCTctcgaaaattattattggcgATACACATCAGCGTCAGAACTAGTCAACATGATTTTAGCATTTGTGGAAACGCGTGCATTTCAATTATTTCAAACACCAGAGTTTTTAACGTTAAGTGAATCGATGGTCCAAATGATTATGTGCAGAAATTTGGAAGTAGCTGAAGTACGGAAATTTGAAGCAATGTTAAGCTGGACacattataaaataagaacTAAAACGTCGAATAAATTGGACGCCCAATTAGAATATAATTGTATAATGGAACGTTTAACTCGCGATCTTAAACTCTATAGAATAACACCACAAGAACTAATaaagGTTGTATTGCCGTCGAAAGCGATTAAAAATGAACGTATTTTAGAGACGTTAATGTTCCAAGCAAACTCGGGCATGTATCGAATACAAGACTCATATTTAAAAGAATGTACTCAAAGACTCCAGAAGCAAGACTCGCGTTTCTCCGAATGGGAATCGTTTGATTACAGTGCGTAG
Protein Sequence
MMCELTSDCIVMDVTEPSPLYDNNHYHEECLRCNSCGLNLTGPNQKRARRFKNQILCDLHFADVALMECSDFMQQLRSFKPQSLGCAVARRKSSTTLIFPLPPQACSDEFCEEFPHNLIPTPGYWIECSRQKITSNTIWDESEESERDTGLPEGDEDDEATDGHSGHHHLHHHDRGCNDLYEDDEDDDSMSPRKKTTIEEQWEKNQGFELTSVEQETYEKYFYGTEHWNYFTNDEDLGPVILSIKQETLNSRDQFRILVRAISYTVHGLIPASCVFADRYNREEVVRSLGKEVNINPPLVLGQLPDTPEELLKLDQVFIKSELKVGVIYVKEGQYTEEEILDNNDNSPLFEEFLQVLGEKVRLKGFDKYKGGLDTVHDLTGLYSVYTNWRNIEIMFHVSTQLPYERHDPQKLQRKRHIGNDIVCVVFLEADNTSFSPACIKSHFLHTFILVRTSPRIKRKPTRYEVSVVTRDEVGAYKPYLWEQSVFDKGTMFREWILTKIVNGERASYSAPKFARMQERTRSQMLEDIVANLANHAETGQIPKPYRRGSWRPIGHMRPSSPLLDSVRDQFEDYDQLAKDFTRMFLNTEANTLANAALFDVVFMVGQSKQKVKFIGVRAILGVRSRVFQEMLYGIQTGFGSPQVPVAELLARPAPTLMSPQQSRPKSSNFLQVPDIETPRPKSVPSSPMVKRAFSRLGTITAGWGRSIRKQHTHLSVDDKKKWSSSQDCSNKDGKDKDGKDKSAMPQLAVPRLSVCADAQKVDRAKLAQTEFCIIEFDPETFRILLDYLHTGSCPLTCASIPGLICAAEHYDLPELLQACFHHAKQFLRIDVVCVMLVSLENYYWRYTSASELVNMILAFVETRAFQLFQTPEFLTLSESMVQMIMCRNLEVAEVRKFEAMLSWTHYKIRTKTSNKLDAQLEYNCIMERLTRDLKLYRITPQELIKVVLPSKAIKNERILETLMFQANSGMYRIQDSYLKECTQRLQKQDSRFSEWESFDYSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01041059; iTF_00873206; iTF_01040276; iTF_00693986; iTF_00755938; iTF_01170754; iTF_01229154; iTF_00739267; iTF_00271492; iTF_00318244; iTF_01254948; iTF_00219237; iTF_00825989; iTF_01225990; iTF_01275545; iTF_00216519; iTF_00958087; iTF_00215144; iTF_01510920; iTF_01216938; iTF_01050507; iTF_00763980; iTF_00386565; iTF_01365685; iTF_00154652; iTF_00884381; iTF_00370349; iTF_01299438; iTF_00439649; iTF_00262808; iTF_00084688; iTF_00085537; iTF_00088961; iTF_00086443; iTF_00088172; iTF_00087324; iTF_01169295; iTF_00219920; iTF_01295344; iTF_00854178; iTF_00003905; iTF_01024225; iTF_00626338; iTF_01120997; iTF_00978537; iTF_00399690; iTF_00422826; iTF_00965325; iTF_00434291; iTF_00032184; iTF_00030362; iTF_00789503; iTF_01291958; iTF_00058098; iTF_00058858; iTF_00349395; iTF_01539731; iTF_00963316; iTF_00652981; iTF_01379435; iTF_00414476; iTF_01497618; iTF_00343322; iTF_01101498; iTF_01100763; iTF_01103707; iTF_00459932; iTF_01111169; iTF_00738508; iTF_00168659; iTF_01215223; iTF_00051163; iTF_00668928; iTF_01023189; iTF_01426905; iTF_00215831; iTF_00305143; iTF_00857815; iTF_00963959; iTF_00762674; iTF_01309591; iTF_00757462; iTF_00138264; iTF_00387416; iTF_00393720; iTF_00089762; iTF_00980309; iTF_00869023; iTF_00691328; iTF_01047577; iTF_00413690; iTF_01435162; iTF_01524154; iTF_00004795; iTF_00022299; iTF_00228091; iTF_00740988; iTF_01371548; iTF_00228797; iTF_00335229; iTF_01343229; iTF_01344161; iTF_00952862; iTF_01141822; iTF_00974911; iTF_01465567; iTF_00306404; iTF_01469896; iTF_01469044; iTF_00197504; iTF_00220704; iTF_00767360; iTF_00768949; iTF_01104901; iTF_00029477; iTF_00029479; iTF_01137055; iTF_00911232; iTF_01013571; iTF_00813860; iTF_00841990; iTF_01310726; iTF_01481062; iTF_01329959; iTF_01366472; iTF_00853001; iTF_01014796; iTF_00870733; iTF_00814544; iTF_01566386; iTF_01227475; iTF_00987284; iTF_00639702; iTF_00249111; iTF_00392889; iTF_00647354; iTF_01410141; iTF_00929726; iTF_01240998; iTF_01244246; iTF_00792344; iTF_00431581; iTF_00328383; iTF_00329795; iTF_01290559;
90% Identity
iTF_01040276;
80% Identity
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