Malt022409.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Monochamus alternatus
Gene Symbol
RAP1GAP
Assembly
GCA_037114965.1
Location
CM073429.1:62305380-62334037[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 0.0016 1.1 10.9 0.0 6 43 491 531 487 549 0.84
2 2 8.1e-09 5.6e-06 28.0 0.0 50 108 666 724 656 726 0.90

Sequence Information

Coding Sequence
ATGGCGAAGGGAAAACATGAATTCTGCGAAGAATTCCCTCACAATTTCATTCCCACACCTGGATACTGGATAGAATGTTCCCGACAGAAGATCACCTCTGACACCATCTGGGATGAGAGCGAATCCGAGCATGAAAACGAGATCCAAGAAGGAGAGGAAGAAGAAGACAATACCGACGGAATGGAGCACGAGAACGGTTTCAGCAGAAGAAGAGATCGAAGCTGTAACGATTTGTACGAGGACGACGAGGACGACTCATCGTCGCCTAAAAAGAAAACGGCTATAGAGGAACAGTGGGAGAAAAACCAAGGTTTTGAGTTAACGAGCGTGGAACAAGAGACCTACGAGAAGTACTTCTACGGTACTGAGCACTGGAACTACTTTACCAACGATGAAGACTTAGGCCCTGTTATATTGTCTATTAAACAAGAGACCCTTAATTCTAGAGATCAATTTAgAATATTGGTGAGAGCTATTAGTTACACAGTTCACGGTTTAATCCCGGCAAGTTGTGTTTTCGCAGATCGATATAATCGGGAGGAAGTGGTGAGATCTTTAGGAAAAGAAGTCAACATCAACCCGCCTCTAACACTAGGGCAACTTCCTGATACGCCCGAGGAACTCCTAAAACTGGATCAGgtgTTCATAAAATCAGAACTGAAAGTAGGTGTAATATACGTCAAAGAAGGCCAATACACCGAAGAAGAAATCCTAGACAATAACGATAACTCTTTTATGTTTGAAGAATTCCTGCAGATACTAGGAGAAAAAGTTCGATTAAAAGGATTTGATAAATACAAAGGAGGGCTGGATACAGTGCACGACCTAACAGgtTTGTACTCTGTCTACACAAACTGGAGGAATATTGAGATAATGTTCCACGTAAGTACGCTGTTGCCATACGAACGCCATGATCCACAAAAACTGCAGAGGAAAAGGCACATAGGTAACGACATAGTGTGTGTGGTTTTTCTCGAAGCAGACAACACATCATTTTCACCGGCTTGTATAAAGAGTCATTTTCTCCATACTTTTATACTAGTGAGGACTTCGCCAAGGATCAAACGAAAACCCACCCGGTATGAAGTGTCGGTAGTTACAAGAGACGAAGTGGGCGCCTACAAGCCCTACCTTTGGGAGCAAAGTGTTTTCGATAAGGGTCCCATGTTTCGCGAGTGGCTACTGACGAAAATAGTGAACGGCGAGAGAGCCAGCTACTCGGCGCCGAAATTCGCCAGGATGCAGGAAAGGACCAGGTCGCAGATGCTGGAGGACATCGTCGCCAACCTACAGAACCACGCCGAGACCGGTCAGATTCCCAAGCCGTACAGAAGagGATCTTGGAGGCCTATCGGACACATGAGACCGTCATCCCCCTTGCTGGACAGCGTACGAGACCAGTTCGAAGACTACGACCAAATCGCGAAAGACTTTACCAGGATGTTCCTAAACACCGAAGCAAACACGCTGGCCAATGCCCAACTCTTCGACGTCGCCTTCCTCGTCGGCCAATCCAAGCAGAAGGTGAAGCTGGTCGGCGTCAGGGCTATCCTGGGGGTCCGAAGCAGGGTGTTCCAGGAGATGCTGTACGGGATCCAAACCGGTTTCGGTTCTCCGCAGGTGCCAGTTGCTGAGCTGTTAGCGAGGCCGGTTCCGACGCTACTCAGCCCGCAGCAGGCACGGCCGAAGAGTAGCAACTTCCTGCAGGTGCCAGACATCGAGTCGCCTAGACCCAAGAGCGTGCCCAGTTCGCCCATGGTGAAGAGGGCGTTCACGAGGCTGGGGACGATCACCGCTGGGTGGGGTAGGTCCATCAGGAAGCACAACACCCAGCAGTTGTCGGCGGACGACAAGAAGAAATGGGCTAGCAGTCAGGATTGTTCTAACAAAGAAGGGAAGGATAAGGAGGGCAAGGACAAACCCTCGCTGTCCCAACTCCCCGTTCCGAGACTCAGCGTTTGCGCAGATGCTCAAAAAGTAGACCGGGCGAAACTGGCCCAGACTgaattttctattattgaatTCGATCCCGAAACATTTCGAATATTGTTGGACTATCTTCATACAGGGTCTTGTCCGTTAACGTGTTCAACAATACCCGGACTGATCTGTGCAGCTGAGCATTACGACCTGCCCGAACTGCTGCAAGCCTGCTTCCACCACGCCAAACAGTTCCTGAGAATAGATGTGGTGTGCTGTATGCTGTGTTCTCTGGAGAACTACTATTGGAGGTACACATCGGCTTCTGAACTTGTAAATATGATCCTGGCTTTTGTGGAAACAAGAGCGTATGCCTTATTTCAAACTAGCGAATTTCTAAATCTGAGTGAATCCATGGTGCAAATGATAATGTGCAGGAATCTAGAGGTGCCCGAAGTACGAAAATTTGAGGCGATGTTAGCCTGGGCTAGGCACAAAATTCGGACGAAAACTTCTAGTAAACTGGACGCTAAGTTAGAGTTTAAATGTATTATGGAACGCTTAGCTAGGGATCTAAAATTGTACAGAATATCACCACAGGAACTCATTAAGGTTGTGTTACCCTCGAAAGCTATTAAAAACGAGAGGATATTAGAGACCCTAATGTTCCAAGCCAACTCTGGCATGTACAGAATTCAGGATTCCTACATCAAGGAATGCACCCAAAGACTGCAAAAACAGGATTCCCGCTTTTCGGAATGGGAGTCTTTCGACTACAGCAATTAG
Protein Sequence
MAKGKHEFCEEFPHNFIPTPGYWIECSRQKITSDTIWDESESEHENEIQEGEEEEDNTDGMEHENGFSRRRDRSCNDLYEDDEDDSSSPKKKTAIEEQWEKNQGFELTSVEQETYEKYFYGTEHWNYFTNDEDLGPVILSIKQETLNSRDQFRILVRAISYTVHGLIPASCVFADRYNREEVVRSLGKEVNINPPLTLGQLPDTPEELLKLDQVFIKSELKVGVIYVKEGQYTEEEILDNNDNSFMFEEFLQILGEKVRLKGFDKYKGGLDTVHDLTGLYSVYTNWRNIEIMFHVSTLLPYERHDPQKLQRKRHIGNDIVCVVFLEADNTSFSPACIKSHFLHTFILVRTSPRIKRKPTRYEVSVVTRDEVGAYKPYLWEQSVFDKGPMFREWLLTKIVNGERASYSAPKFARMQERTRSQMLEDIVANLQNHAETGQIPKPYRRGSWRPIGHMRPSSPLLDSVRDQFEDYDQIAKDFTRMFLNTEANTLANAQLFDVAFLVGQSKQKVKLVGVRAILGVRSRVFQEMLYGIQTGFGSPQVPVAELLARPVPTLLSPQQARPKSSNFLQVPDIESPRPKSVPSSPMVKRAFTRLGTITAGWGRSIRKHNTQQLSADDKKKWASSQDCSNKEGKDKEGKDKPSLSQLPVPRLSVCADAQKVDRAKLAQTEFSIIEFDPETFRILLDYLHTGSCPLTCSTIPGLICAAEHYDLPELLQACFHHAKQFLRIDVVCCMLCSLENYYWRYTSASELVNMILAFVETRAYALFQTSEFLNLSESMVQMIMCRNLEVPEVRKFEAMLAWARHKIRTKTSSKLDAKLEFKCIMERLARDLKLYRISPQELIKVVLPSKAIKNERILETLMFQANSGMYRIQDSYIKECTQRLQKQDSRFSEWESFDYSN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01039428;
90% Identity
iTF_01013571; iTF_01310726; iTF_01163338; iTF_00965325; iTF_01227475; iTF_00369679; iTF_00048753; iTF_00022299; iTF_01244246; iTF_01240998; iTF_00413690; iTF_00032184; iTF_00030362; iTF_00792344; iTF_00056764;
80% Identity
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