Nina007097.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Napeogenes inachia
Gene Symbol
-
Assembly
GCA_959347355.1
Location
OY365793.1:27204832-27214510[-]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 4.5e-17 1.5e-13 51.0 0.0 7 70 286 349 282 353 0.93

Sequence Information

Coding Sequence
ATGTCGGACGAAATGGCGGTGGGTGATAACGCATCAAATGACGAACATAATGTCGGCAGCGACGATTTGGGGATGGAGGCAGTGGACTCTACAAACGCTACAGAACTTTCAGGCGAGTCAACAGCTGCTGAGACAGAAATTAAAGCAGAACAAACAGGTGATACTGATGCCCAGCCTGAAATAAAAACAGAACTAGAAGAAAAGGAAGATGAGAATGATGAAGTTAAAAAAGAGCAAAAAGAAGTACTAGAAATGATGGAAGAGACAGAGACTCAAGAGAATAGTGATGAAGTCACACGTGGTGTTAAGAGGAGAGCATCGGCAGCATTCAGTGATGATGGGGAAGAGTTCAAAGGCTTTGATCAATGTGAGCAGAGTAGTCTAACGGATTACAACAAAATTGTTGCAATTTCCGATCATTTCATGCTATCGGAAGAGGCGAGAAGAGTTAAACAGAGAACCTCCAGTGATAATGATGGTTTCAAAGGTTTTGACCTTATTGGGCATAACAACCTGACCGGATATTGTCAGGTTTTAGAACGCCTGGAAGCTGAAGTTTCTGCAGCGGCCAAGACATTAACCCCGATCCGTCGTGTGATGACAACCCTGCGCAAGCGCCAGAACACAGGTGGGTCAACAAAGTGGTCTGAACACCTGGAGGCGGAGGTTTCTGCTATGGTGAGGAGCTTCTCCACCGATGATGAGAGCAAAGGGAGAAGGCGGGCTGatggATCAAGACCGTCGTCAGCATTATCATCTAGATCAGATGGTGATGGCGCTGCATCTACTGATGCATCTTCATCACCAGCGGGTCGTGTCGGTCGTCGCGCCACGACAGAGATGTCGTCACCTCTACTAAGGATTCCTTTAGAGAAGGGATGGAAGCGAGAGTTGGTATATCGGGCGGCGGGGGCCTCCAGTGAAGTGCCAAGACGGAAtgcagatatttattattacactcCAAATGGGAAGAAGCTAAGATCTACCAGAGAgGTCTCCGAGCATTTGTCTGGTACTGGTCTCACATTAGAAAACTTTTCCTTCTTCAAAGAGCCTTTAGGAATTGATGACCCTGAGAAAGAAATAATACGggaTGCAAAAGTTCAGTCGCGTCGTGTTGAGTCTCCAGTACCAGTGGCGGTTCCATCCTTGGAGTCCAAGCGTACTCCCAAACCGAAGGCCCCTAAAGGAGCCAGCCCCGAGCCGGTCAACAAGTCACCTCCTGCTAAATTAAAGGTGAAGTCAATGGGTTCTCGCCTTAGCAGCAATGGCACCACTGCCCCAAAGCAGATAAAGAAACCTAGCACTCCACAGACAGCAGTCACACAGGACAATAATAATTCAGCAGCTTGGAAAAAACCAAGGGGCCCGCCGCCGCTGCAGCCGCGCCCCGCGCACCCTGCTCAGCCCGTGCATCCCGTACAATCGGCGTCGCAAGTGCATCCCACTCAGCCAGTACATCCCGCGCAGCCCTCGCATCCCACGCAGCCCGGGCACTCTTCATTGCAAACGCCCGCCCCGCATCCCCCACACACACCGGAGCGGGACGCACCTCCTGGACTCCACCACCAGCGTCGTCAGGTTCAGCAACCGTGCTCGATGACGTGCGGGGCGGGCGTGCCGTCGCTGGCGTGCGGCGCCTGTCTGTGCCTGTACCATCCCGCCTGCGTGGGGCTGCGAGCGCCCGTGGAACGGTTCCTATGTAAGaaCTGCCGCAAATCCTCTCCACCACTAGAGCCGCCTCCATTAACTCACAAGTCCGGTGTGACGTTATCGGCTGGTATGCCTTCCGCATCCAGTGCCAGACGCCTGCCAGTGCCGGTGCCGGTGCCGGTGCCCGCTAAAGGAAGGAACGATAAACGAGTGCTGTTAAGGATGAAGGTGGCTGGCGGTGGTCCGGATGGAGAACGTCTCTGGTCGGTCTCAAAGCCGGGCGCGCCTCCCCCTTCTCCCCCAACTCCCACGCCCGCCTCCGCCGCCCCCCTCCCCCCGGCTCCTCTCCCCGCGCCGCCCGTGTGCCGGCCCTCCCTGCCGCAGTCGCTAGTCGTACTAAACGGGAGACGGTTCATTGTTGTCGCGAGAGCCATGCAGCATGAGGTCAAGGTGACTCGTAGAGGCGTGGCCAACGGAGCCGCCTCCCCCCCCGCGCCGCCTGCAGCGCTACGGCGTAGAATCAAACGCGATGACACGGATCACTTCACACCCTTCTACGAGAAGGCAAAGGAGAGCGGCTTGAATGTCGCCGTGCAGATCTTCCAGTACCTGGGCATGCGTGACGTGGCGCGTGCGGCGCGCGTGTGCTCGCTGTGGAAGCAGCTGGCCGCCGCGCCCGCGCTGTGGAGGCACGTGCGGATGAAGAACTCGCATGTGAGCGAGTGGTCGGGTCTATGTGCGTCACTGAAGCGCCACGGCACGCGCTGGCTGGACCTCCGCAAGATGCTGCTGCCGCCCAATGACACCCCGTTCTGGGACCAGTTCTCGGAGCACATCGGCACCGTCGACACGCTCGAGAGGCTGGAGCTGTGCCGGTGTCCCGCCCGCGCGGTGGAGGCGGCGTGCGCGCGGTTGCCTGGCCTGCGCGCACTGGCCGCGCCCGCCATACGGGACGCCCGGCTCGACCCCGCGCCGCTGGCAGCCCTGCCGCGACTGGAATTACTGCGTCTCAAGAGTCTAGCCGGGCTATCCTTGACGCGTGACTTGCGTCCCCTGGCCGCATTATCTCGGCTGCAGCACTTGTCCCTCACCTCTATAAAGGAGCTGGGTTGGTGCGCCTGCGAGGTGGTCGGTCAGTTGGAACAGCTCGAGTCCCTGGAGCTGGGAGAGTGCTCTTTCGGCGGTTCCTTCGCCAGTGCCCTCGGCAAGCTCGTCAAGCTAAGGAAATTGAGGTTGGAGCGAGGGGTGGCGCACTGTGCCGCGCCTGCGTTGTTGCGAGCGCTGGCAGCCCTGCCCAAGCTCACGCGATTAGAGCTTGTCAATTTTGACGTTAAGGTCGGATTCGACGATGCTCTCGCGGAATGCAAAAATATCCAGAGACTACTCATCATACCCACATACGTGTCCCAATCCGCCACTACTAATAAGCAGGTGCTGAGCGGAGTGCTGCGGCTGAAGGAGACGCTGACGCACCTCATGTGGGGCGTCACCATAGAACTACTGCGGGTCACGGAGCTGTTCATCGACCAGTGCGAGGCGAGCGACGGAGACAACAAGCGGCGCGACGTGGGGGAGTGCATCCCGGTACTGAAGCCGGTGCCGGGTTGCCGGCTGCCCGACGACCACCGCACGGTGGCCGGCCCGCCACAGGTGGAGATCCTGCCCATTCCGACTCTCCAGCGGCTGCTGGCGGCTCAGTTGCCGCGCACCAAGCTCAAGCTGCTCCGGATCCCCTTCCACGCCACGTGGAGACAGTCGCTGGCGGACTTCCAATAG
Protein Sequence
MSDEMAVGDNASNDEHNVGSDDLGMEAVDSTNATELSGESTAAETEIKAEQTGDTDAQPEIKTELEEKEDENDEVKKEQKEVLEMMEETETQENSDEVTRGVKRRASAAFSDDGEEFKGFDQCEQSSLTDYNKIVAISDHFMLSEEARRVKQRTSSDNDGFKGFDLIGHNNLTGYCQVLERLEAEVSAAAKTLTPIRRVMTTLRKRQNTGGSTKWSEHLEAEVSAMVRSFSTDDESKGRRRADGSRPSSALSSRSDGDGAASTDASSSPAGRVGRRATTEMSSPLLRIPLEKGWKRELVYRAAGASSEVPRRNADIYYYTPNGKKLRSTREVSEHLSGTGLTLENFSFFKEPLGIDDPEKEIIRDAKVQSRRVESPVPVAVPSLESKRTPKPKAPKGASPEPVNKSPPAKLKVKSMGSRLSSNGTTAPKQIKKPSTPQTAVTQDNNNSAAWKKPRGPPPLQPRPAHPAQPVHPVQSASQVHPTQPVHPAQPSHPTQPGHSSLQTPAPHPPHTPERDAPPGLHHQRRQVQQPCSMTCGAGVPSLACGACLCLYHPACVGLRAPVERFLCKNCRKSSPPLEPPPLTHKSGVTLSAGMPSASSARRLPVPVPVPVPAKGRNDKRVLLRMKVAGGGPDGERLWSVSKPGAPPPSPPTPTPASAAPLPPAPLPAPPVCRPSLPQSLVVLNGRRFIVVARAMQHEVKVTRRGVANGAASPPAPPAALRRRIKRDDTDHFTPFYEKAKESGLNVAVQIFQYLGMRDVARAARVCSLWKQLAAAPALWRHVRMKNSHVSEWSGLCASLKRHGTRWLDLRKMLLPPNDTPFWDQFSEHIGTVDTLERLELCRCPARAVEAACARLPGLRALAAPAIRDARLDPAPLAALPRLELLRLKSLAGLSLTRDLRPLAALSRLQHLSLTSIKELGWCACEVVGQLEQLESLELGECSFGGSFASALGKLVKLRKLRLERGVAHCAAPALLRALAALPKLTRLELVNFDVKVGFDDALAECKNIQRLLIIPTYVSQSATTNKQVLSGVLRLKETLTHLMWGVTIELLRVTELFIDQCEASDGDNKRRDVGECIPVLKPVPGCRLPDDHRTVAGPPQVEILPIPTLQRLLAAQLPRTKLKLLRIPFHATWRQSLADFQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00842698;
90% Identity
iTF_01034609;
80% Identity
-