Basic Information

Insect: Mylabris variabilis
Gene Symbol: prdm10
Assembly: GCA_037464815.1
Location: JAZBGW010000617.1:11659-17740[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 4.3e-06 0.00026 21.2 0.5 2 23 494 515 493 515 0.97

2 13 5.2 3.1e+02 2.1 0.1 2 16 558 572 557 582 0.84

3 13 0.0035 0.21 12.1 0.5 1 23 601 623 601 623 0.92

4 13 0.00059 0.035 14.5 1.0 1 23 634 656 634 656 0.96

5 13 5.8e-05 0.0035 17.7 2.1 1 23 675 697 675 697 0.98

6 13 0.00069 0.041 14.3 0.9 2 23 706 727 705 727 0.97

7 13 0.021 1.3 9.6 0.7 1 20 734 753 734 756 0.91

8 13 0.0018 0.11 13.0 5.4 1 23 762 785 762 785 0.96

9 13 0.00018 0.011 16.2 3.9 1 23 790 812 790 812 0.97

10 13 0.0008 0.048 14.1 4.8 1 23 818 841 818 841 0.89

11 13 0.0017 0.1 13.0 1.7 1 23 886 909 886 909 0.97

12 13 0.00021 0.013 15.9 3.9 1 23 931 954 931 954 0.97

13 13 0.0015 0.09 13.2 3.4 3 23 994 1015 992 1015 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	4.3e-06	0.00026	21.2	0.5	2	23	494	515	493	515	0.97
2	13	5.2	3.1e+02	2.1	0.1	2	16	558	572	557	582	0.84
3	13	0.0035	0.21	12.1	0.5	1	23	601	623	601	623	0.92
4	13	0.00059	0.035	14.5	1.0	1	23	634	656	634	656	0.96
5	13	5.8e-05	0.0035	17.7	2.1	1	23	675	697	675	697	0.98
6	13	0.00069	0.041	14.3	0.9	2	23	706	727	705	727	0.97
7	13	0.021	1.3	9.6	0.7	1	20	734	753	734	756	0.91
8	13	0.0018	0.11	13.0	5.4	1	23	762	785	762	785	0.96
9	13	0.00018	0.011	16.2	3.9	1	23	790	812	790	812	0.97
10	13	0.0008	0.048	14.1	4.8	1	23	818	841	818	841	0.89
11	13	0.0017	0.1	13.0	1.7	1	23	886	909	886	909	0.97
12	13	0.00021	0.013	15.9	3.9	1	23	931	954	931	954	0.97
13	13	0.0015	0.09	13.2	3.4	3	23	994	1015	992	1015	0.96

Sequence Information

Coding Sequence: aTGGATGCAATAGTAGAGGAGCCACCCGATGAGGGGGCtcaagatttaaatttaatcgatgCTGGACAGTGGACACAAAATGGACAATTACcaaataattcaacatttctttatattgctgtAGAATATGTTAAAGATGAATATAAGATTAACCAAAATACTTTAATAAACCAACACAATGATGGTTTTGACTTTGAACAAcatcagcaacaacaacaacaaaaccaccaacaacatcatcatgtTAGTCCTTTAGATCCGAATATGAGTAGTGTAGCACATTATAGTCCAGTTTATAGTGATACATCAAATGAATTTAATCCAATTGTTATACATCAATTAGTAGAATCAGATACAACAAATGgtacagtaacaacaacaacgacaacacaAAAtgatattatcaacaatttaacaACATCATTAGTTGAAACAATGCCAGTATTGTGCAATAATGATATACGTGATGTtgttaataatcaatttttacaaatggtaacaaatgataatacaccaccaacaacaacaacaacaacaaatatatcaATCAATAATGGTGATAATACTAGTGATAATCTTGTAAatcatgataataataataataataatgttagtAGTAATAATGAGGATCAAAGACAAGtagaattattgataacagATCAAGAAACTGGTATATCGTATAGTGTACGTTCACAAGAATTTTTAGTTGAACGTTGTTTAGAtgatgaacaattattaaatgcaTTAACACCAGATCCACTATTAGAATCGGATTTATTAACATTAGATGAGAATACATTGAAAACTGAATTGAATGATGATATTATTAATACATCAGTTATTGATACAACaaatgttattaataattatgtaaCAAGTTTAACAACAACACCGATTATACAAAGTGATATTAAAATTACTGATAATCATAATGataatcaatataaaattgaaacaaggcgacataaaaatttagaaattgattTTGAAGATCAGTTGTTGTCGAAAGTTTATAGTATTATTGATAAGCCAGTATTATCAAGGGCACGTGCTACATTACCGGAAACATatcttgtttttaataaaattgataataatgaaaatattggtGTATTTGCTAAACGAATGATACCAAAACGTACACAATTTGGACCATTAACtggtattttaacaaatttcgatGAGAATCAATTTAAAGAagatgtaaataatttaatatttttaattaaaaatgataatgacAATACAATTGTTCGTTTAGATGTATCAGATGAAAATGTTTCAAATTGGATGAGTTTCGTGAGGAAAgctagaaattttaatgaacaaaACCTTGTAATTAGTCAAGAAGGTAATGgtttatattttacaacaacgAAAAATATTGCACCTAAAGAGGAATTAAAagttggttattgtttaaattatgcAAATCGTTATAAATTAACTGTATTAAATCCACCAGAAGAACGTACATGGCAATGTTTTGAATGTACAGAAACATTTACAACATCAGACGAATtacaaaaacatttaaatatacatGATAATGATTGTGGTAATGATAATGTAAAAGATGAGAATATAAAACCacgaaagaaaattaataaaaatttaaaacgaaaattaacaacagcattacaacaaaaaactaataataatgaagcattaaaatgtaataattgtaatcaacTATTTATACAAACTGGTAAATTAGCATTAAGGAATCAtttaattgagaaacatttaaTGACACGTTTCAATTCTATTGATGAACATTTTTCATCTATTGGtgattattttaaatgtgataGTTGCGGTGTTGTTTTTAAtacagaaaatttattaaaaatacataattatcaacattatccTGATAATTCTGATGAACAAACAAATCATATTTGTCCAAGTTGTCAACGTAAATTTCCAACACAACGTCAATTAGTAACACATGTTTCtgtacataatttaattaataatggtgtacaacaacaaaaacaacctGAGAAACAGGAGAGTTTTAAATGTTCAGTTTGTCATAAGATTTTCGCGTTACGTGAACGCTTACGGcgtCATATGTTGGTACATGGTTCAGATGAATCGAAACCATTACAATGTAAAACATGTAATAAacgttttttaaataattccgCCTTAGCTGgtcatttaaaaacacattttgttggtaaaaaaatctttgaatGTCCAATATGTAAAGAGAGTTTTGAtcatgtattaaaattaaaattacatgtACCGAAACattgtgaaaataatttatattcatGTCCACATTGTACAAAAGTATGTAAAAAGTATAGTATGATAAGGAAACATATAAGGGCATTTCATTGTGATCAAAAACATAATTGTCCACATTGTACAAAAATGTTTCCAACattagataaattaaaaatgcatCTATTACGTCATTCTGATCATCGTGAATTTCTATGTTCAGATTGTGGTAAACAATTTAAACgtaaagataaattaaaagaacatTGTAAAAGGATGCATTCAGAAGAACGTGAAAATAATATaccgaaaattaataataataataataataatataaataacaataataataaacaacaatcgaaaaaattgaatccAAAAGTTGAACCAACTGATTTTCATCgttttatatataaatgtCATACGTGTTTGATTGGTTTTAAAAGACGTGGTATGTTAGTGAATCATTTAGCAAAACGTCATCCAGATATACCACCAGATTCAGTACCTGAATTAAATTTACCAATATTACAAACAACACgtgattattattgtcaaCATTGTGATAAAGTATATAAAAGTAGTTCAAAACGTAAAGCacatatattaaaaaatcatcCAGGTGCTGCATTACCAATGAGTAATAGAAAACATGGTTCATATCCAGATAATACAAATTTACCAAATCCAACATTTTCACAAACTGTTGGTAGTATAACAACACGTCCACAAAATTGTAATTGGTGTCATAAACAATATGCAAGTAAAgcgaaattattacaacatcAAAGGAAGAAACATAATGAACAAttagtacaacaacaacaacaagaacaacaaatccagcaacaacaacaagatgaaCAACAACCACAAGAAAATCAAGAAATGAAAGATATTAATGATTTTGATGAACACAATTTAATAAACGAATATAAAGTTACTGAAGTTAATATATTAGATAATACTTTAATTAAAGATTACGAACATGGTCGTGATAATGATCAATATTTAGTGGCAATTGGTAATGGtgataattttacaacaaacgATTCACATCTTTACCGTTTATTAACAACAAGTAAtgGTTTAGTACCACCACGTTGA
Protein Sequence: MDAIVEEPPDEGAQDLNLIDAGQWTQNGQLPNNSTFLYIAVEYVKDEYKINQNTLINQHNDGFDFEQHQQQQQQNHQQHHHVSPLDPNMSSVAHYSPVYSDTSNEFNPIVIHQLVESDTTNGTVTTTTTTQNDIINNLTTSLVETMPVLCNNDIRDVVNNQFLQMVTNDNTPPTTTTTTNISINNGDNTSDNLVNHDNNNNNNVSSNNEDQRQVELLITDQETGISYSVRSQEFLVERCLDDEQLLNALTPDPLLESDLLTLDENTLKTELNDDIINTSVIDTTNVINNYVTSLTTTPIIQSDIKITDNHNDNQYKIETRRHKNLEIDFEDQLLSKVYSIIDKPVLSRARATLPETYLVFNKIDNNENIGVFAKRMIPKRTQFGPLTGILTNFDENQFKEDVNNLIFLIKNDNDNTIVRLDVSDENVSNWMSFVRKARNFNEQNLVISQEGNGLYFTTTKNIAPKEELKVGYCLNYANRYKLTVLNPPEERTWQCFECTETFTTSDELQKHLNIHDNDCGNDNVKDENIKPRKKINKNLKRKLTTALQQKTNNNEALKCNNCNQLFIQTGKLALRNHLIEKHLMTRFNSIDEHFSSIGDYFKCDSCGVVFNTENLLKIHNYQHYPDNSDEQTNHICPSCQRKFPTQRQLVTHVSVHNLINNGVQQQKQPEKQESFKCSVCHKIFALRERLRRHMLVHGSDESKPLQCKTCNKRFLNNSALAGHLKTHFVGKKIFECPICKESFDHVLKLKLHVPKHCENNLYSCPHCTKVCKKYSMIRKHIRAFHCDQKHNCPHCTKMFPTLDKLKMHLLRHSDHREFLCSDCGKQFKRKDKLKEHCKRMHSEERENNIPKINNNNNNNINNNNNKQQSKKLNPKVEPTDFHRFIYKCHTCLIGFKRRGMLVNHLAKRHPDIPPDSVPELNLPILQTTRDYYCQHCDKVYKSSSKRKAHILKNHPGAALPMSNRKHGSYPDNTNLPNPTFSQTVGSITTRPQNCNWCHKQYASKAKLLQHQRKKHNEQLVQQQQQEQQIQQQQQDEQQPQENQEMKDINDFDEHNLINEYKVTEVNILDNTLIKDYEHGRDNDQYLVAIGNGDNFTTNDSHLYRLLTTSNGLVPPR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01366547;
90% Identity: iTF_00813892; iTF_00814583;
80% Identity: -