Basic Information

Gene Symbol
Zfpm1
Assembly
GCA_037114965.1
Location
CM073428.1:75090146-75093241[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 8.8 6.4e+02 2.6 0.1 2 23 7 28 6 28 0.92
2 15 0.041 3 9.9 0.4 1 23 550 573 550 573 0.90
3 15 0.016 1.2 11.2 0.1 2 23 651 673 650 673 0.93
4 15 0.0012 0.084 14.8 1.1 1 23 681 703 681 703 0.98
5 15 0.0013 0.094 14.7 1.4 2 23 706 727 705 727 0.97
6 15 0.065 4.7 9.3 2.5 1 23 733 755 733 755 0.80
7 15 0.00023 0.017 17.0 5.1 2 23 762 783 761 784 0.95
8 15 0.9 65 5.7 1.1 5 23 797 815 796 815 0.95
9 15 0.00015 0.011 17.6 2.3 3 23 822 843 821 843 0.97
10 15 0.022 1.6 10.8 0.2 2 23 859 879 858 879 0.97
11 15 0.00042 0.031 16.2 1.4 1 20 885 904 885 907 0.92
12 15 0.00028 0.02 16.8 0.2 1 23 915 937 915 937 0.99
13 15 0.0026 0.19 13.7 2.9 1 23 943 965 943 965 0.97
14 15 2.8e-06 0.0002 23.0 2.2 1 23 971 993 971 993 0.98
15 15 0.0035 0.25 13.3 7.0 1 23 999 1021 999 1022 0.96

Sequence Information

Coding Sequence
ATGGACTCAACCAACATTGTTTGTCCAGTTTGTACTTTATATCTAAGGCCAGGAATAACCTTAAAGCAACATTTGTCCTCTCATCCAAAGCAGAAGGTTATAGAGGCCTTGGTAAAGTTGTCTGTGGGTGAAGAGTCAAAAGGTCAAAATGTACCCACACAACCAGATTTAAATGCTGCAAGTAGCTCTCAGGTCAACTCGGCTGTAGTGAATCAGTCATGGAATCAAGCACCCCCAGGTCATTTGGGGCCCCCACCTCATATAACTCCATTACACGGGAACCACGTTTTCATTTATCAACAAAGTATGAGCACGACTTCCCCACAGCCAAATGTTCTAAATGTAAACCCGCTATCGCAGCAGTATGTGTATCCCACTGTTTTCAACCCCCAAATGATGCCATATGTCTATCAACAACAGCAAGTTATAATGTCTAGTAATTCATTGCCACCTCATGTAAGGGCCTTACCATTTGATATACCCAGTACGTCACAAGCGAATATACCAGAGCAATCAGTTGAGAACGGTAGTGAAAATAATGTTGCGCAAAGTAGAATAGAAGAAATCCAAGAGAACAACGGTGAGTCAAGACACGAAGATATAACCAAGGATATTTTTAACGAAACAACTTCGGAGCCGTCAACTGTTAAGAAACAAGAAGACATGGATATAGTCGGTCATGAAGTGAAGACTATGGAAGATTTTGAAAATGAACAACTAATGGTGAACGAAATACCTCCGGAAGAGTATGGTAATGAGAACAATGCAGATTATGAACACGAACAAGTTGATCACGAGGAGTGTATTGATTCTCCACGTTCTCAAACTACCACTCACTCTGACTGGGCATTTCATTCCGATTTGAACAAGGCTTGCCAAACTCAAAATACAAGTAATACCTCACCACGGTCACACATATTAGAAGAGGAAGAACCAGACATGGATACTCAAGAAAACAATGAGGATCAACccgaatatttttatattcaccAACAAAATCAGGAATTTGAAAAACATCCAACTCAGGAGTATTCCGAACCGAATGTTATACCATATACAACAGTTAAGTTGAACACTGAGAGTTACGAACAGTCCGAACCAATTTATACTTCTGCGAATATCTTACACGGTGGAGACCACTTGGATTTTGTTAATATGGAAGATATTGTTATCATAAATGATTTTGCTTCGAATCAGGTTATTTCTCaagttgaaaattttgaaaacacttCTCCTGATAGACCAGGAGTCTTAATGACTATAGGAGATATCGTCGAACAGCCgaaaaatgattttatagagcaaagaGACCTGGAGGAGAGTATGTCGAGAGAGAGCTCCCACGTTAACATAAGGTCTGACGAAAGAATGCCAGCAAGAGGCGAATTGTCTGGTCAGGAGAGTATTGGAGGTGCTAGTGACATAACATGGAATCGTATGCAGTACCAAGAAGGTAGTTCGGGTATGTCACACTCTTACGATTTAATCGGAAGGGAAACTTGGGAGGCATCCGACAGTGACAGTGTAGAAGTGCCAACGATTCAACGGAGACATCCAGTGCAAGTGGACTATCAAAATCATATGGAGTATAACGATAATGAAAATGATACTCCTACTATCGTTAGTTATTCTGGTCCTCCACTTAATTTTAAATGCCCCACGTGTCAGGAAGGTTTTGCTTCGTCAAAAGAAAGAAAAGAACACGAGATCGAGAAACATCCAGAGAAAATAAGTAGAAGTAATTTAATCGGTGGCGATATTGgaaggaaaaaagtaaaaaaactgATAGTAAAGTTAAAATCAGATAAGACTGAGGCCGACAACAACTATGACAATGTTTTtactaataaattgaaaatagagAATAACGTTGAGCAAAACGAAACTCCACCTGCCGAGACTGAGATTAAGCAAGACGAGCCCAATTTAGAATTAAAGGACTTAAAGATAGTGTGTCCGATTTGTGACTGTGTCGTAGAAAATGCCAAAGCTCTAAAGCAGCATAAAATGGAAGTTCACAAGGAAAACGCCAGTGTACGACACAAGTGCCTGACATGTGGAGAGGCTTTTCCTAACGAATATAAATACACAGACCATCTTAAAGTACATCCTCTAGAATGTAGATTATGCGGGAAACTATTCTATAGAAGACAAAATATTCAGTTACATATGAAGAGACATCTGGGCCTCAAGCCGTACAAATGCGAGATCTGCCAAAAATCATTTGTAACCAGACAAAAACACGATGAACATAAAAACATTCACACGGGCGAAGCCCCCATCAAATGCAACTTGTGCGAAGAAACGTTTAGGAGGCATTCAAACTTAGTACAACATCGTAATAGGCACCATTTTCAGCTCAAGAAAAAAGTTAAGGATTACATATGTCAATGTGGCGAAATTTTTCACTCTAAAAAAAAACTCGCATGGCACAAGGAAATCCATGACTCCAAGCCCAAGGCATGTACTCAGTGCAGtgaaaaatttgttcatatGTCAAGTTTAACGAGACATATGCGTCGTGCCCATAACGAGAAGTTTCTCCCGCAAGTAGACAGGGATAACGAAAACGTTCAATGCCCCATCTGCAAAGGTACTTATCTCAGATCTTCCTTGGAAGTACACATCCGTAAGCACAGCGGACAGAGGCCTTTCACGTGCTTGATTTGCAACAAGGATTTCACCACTAAATGGAATCTTAAGTTGCATAAGTGGACGCACGCCAGTCGCACATCCAAGCCCTTCAAGTGCGATCAGTGTAAGGGTGCCTTCATTAGAGAGTCCGATTACATTGCACATATGAACTCTCACAAAAGCGTGCGGCCATACACGTGTAACTACTGCGGAGCTCAGTTCATCAGGAAATACAACTGCATAAGGCACGTTAAGGAACACGAGAATAACAAAACGTTCGTTTGTCAGGTTTGCGGCAAGTCTTTTCATAGGTCGTATTACTTAAAGGATCACATGCTTGTACATAGCGGTATCCGACCTTACTCCTGTCATATTTGTGGGAAAACTTCCACGACTAAGTCTAATCACAATAAACATGTACAAATTCATCATGCTAGGGAACCAGTTagtacagaaaattaa
Protein Sequence
MDSTNIVCPVCTLYLRPGITLKQHLSSHPKQKVIEALVKLSVGEESKGQNVPTQPDLNAASSSQVNSAVVNQSWNQAPPGHLGPPPHITPLHGNHVFIYQQSMSTTSPQPNVLNVNPLSQQYVYPTVFNPQMMPYVYQQQQVIMSSNSLPPHVRALPFDIPSTSQANIPEQSVENGSENNVAQSRIEEIQENNGESRHEDITKDIFNETTSEPSTVKKQEDMDIVGHEVKTMEDFENEQLMVNEIPPEEYGNENNADYEHEQVDHEECIDSPRSQTTTHSDWAFHSDLNKACQTQNTSNTSPRSHILEEEEPDMDTQENNEDQPEYFYIHQQNQEFEKHPTQEYSEPNVIPYTTVKLNTESYEQSEPIYTSANILHGGDHLDFVNMEDIVIINDFASNQVISQVENFENTSPDRPGVLMTIGDIVEQPKNDFIEQRDLEESMSRESSHVNIRSDERMPARGELSGQESIGGASDITWNRMQYQEGSSGMSHSYDLIGRETWEASDSDSVEVPTIQRRHPVQVDYQNHMEYNDNENDTPTIVSYSGPPLNFKCPTCQEGFASSKERKEHEIEKHPEKISRSNLIGGDIGRKKVKKLIVKLKSDKTEADNNYDNVFTNKLKIENNVEQNETPPAETEIKQDEPNLELKDLKIVCPICDCVVENAKALKQHKMEVHKENASVRHKCLTCGEAFPNEYKYTDHLKVHPLECRLCGKLFYRRQNIQLHMKRHLGLKPYKCEICQKSFVTRQKHDEHKNIHTGEAPIKCNLCEETFRRHSNLVQHRNRHHFQLKKKVKDYICQCGEIFHSKKKLAWHKEIHDSKPKACTQCSEKFVHMSSLTRHMRRAHNEKFLPQVDRDNENVQCPICKGTYLRSSLEVHIRKHSGQRPFTCLICNKDFTTKWNLKLHKWTHASRTSKPFKCDQCKGAFIRESDYIAHMNSHKSVRPYTCNYCGAQFIRKYNCIRHVKEHENNKTFVCQVCGKSFHRSYYLKDHMLVHSGIRPYSCHICGKTSTTKSNHNKHVQIHHAREPVSTEN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01370122;
90% Identity
iTF_00110813;
80% Identity
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