Basic Information

Insect: Microplitis mediator
Gene Symbol: zfh1
Assembly: GCA_029852145.1
Location: CM056854.1:3621548-3625974[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 32 0.02 2.8 9.5 2.0 1 23 41 64 41 64 0.96

2 32 0.0072 1 10.9 0.4 2 23 71 93 71 93 0.93

3 32 0.00012 0.017 16.5 2.9 1 23 99 121 99 121 0.97

4 32 0.00043 0.062 14.7 0.2 1 23 125 147 125 147 0.98

5 32 4.5e-05 0.0064 17.8 3.0 3 23 155 175 154 175 0.97

6 32 0.00096 0.14 13.6 0.1 1 23 181 203 181 203 0.98

7 32 0.37 53 5.5 1.5 1 23 209 231 209 231 0.97

8 32 2.1e-07 3.1e-05 25.1 0.2 2 23 238 259 237 259 0.97

9 32 3e-06 0.00043 21.5 1.1 3 23 267 287 266 287 0.98

10 32 4.4e-06 0.00063 21.0 5.0 1 23 293 315 293 315 0.98

11 32 0.0029 0.42 12.1 1.4 1 23 388 410 388 410 0.91

12 32 1.8e-07 2.5e-05 25.4 1.1 1 23 416 438 416 438 0.99

13 32 9.4e-07 0.00013 23.1 0.1 1 23 444 466 444 466 0.98

14 32 0.0012 0.18 13.3 2.5 2 23 473 495 472 495 0.95

15 32 1.4e-05 0.002 19.4 6.5 1 23 500 522 500 522 0.97

16 32 2.8e-05 0.004 18.5 1.5 1 23 531 553 531 553 0.98

17 32 7.4e-06 0.0011 20.3 0.9 1 23 559 581 559 581 0.97

18 32 8.2e-05 0.012 17.0 1.3 2 23 588 609 587 609 0.97

19 32 5.5e-06 0.00079 20.7 3.3 1 23 615 637 615 637 0.98

20 32 3.4e-05 0.0049 18.2 0.5 1 23 643 665 643 665 0.96

21 32 0.16 23 6.7 0.8 1 22 757 778 757 780 0.89

22 32 3e-07 4.3e-05 24.7 1.6 2 23 787 808 786 808 0.97

23 32 3.2e-06 0.00045 21.4 3.0 3 23 848 868 846 868 0.95

24 32 0.0002 0.028 15.8 4.6 2 23 874 895 873 895 0.97

25 32 0.00052 0.075 14.5 0.1 1 23 900 922 900 922 0.98

26 32 4.9e-06 0.00071 20.8 2.7 1 23 930 952 930 952 0.98

27 32 0.035 5 8.7 2.5 1 23 958 981 958 981 0.94

28 32 0.00021 0.03 15.7 0.6 2 23 993 1014 992 1014 0.96

29 32 1e-05 0.0015 19.8 2.0 1 23 1020 1042 1020 1042 0.96

30 32 5.3e-08 7.5e-06 27.0 0.2 1 23 1048 1070 1048 1070 0.98

31 32 4.1e-07 5.9e-05 24.2 0.9 1 23 1076 1098 1076 1098 0.98

32 32 0.00063 0.09 14.2 0.9 1 22 1104 1125 1104 1125 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	32	0.02	2.8	9.5	2.0	1	23	41	64	41	64	0.96
2	32	0.0072	1	10.9	0.4	2	23	71	93	71	93	0.93
3	32	0.00012	0.017	16.5	2.9	1	23	99	121	99	121	0.97
4	32	0.00043	0.062	14.7	0.2	1	23	125	147	125	147	0.98
5	32	4.5e-05	0.0064	17.8	3.0	3	23	155	175	154	175	0.97
6	32	0.00096	0.14	13.6	0.1	1	23	181	203	181	203	0.98
7	32	0.37	53	5.5	1.5	1	23	209	231	209	231	0.97
8	32	2.1e-07	3.1e-05	25.1	0.2	2	23	238	259	237	259	0.97
9	32	3e-06	0.00043	21.5	1.1	3	23	267	287	266	287	0.98
10	32	4.4e-06	0.00063	21.0	5.0	1	23	293	315	293	315	0.98
11	32	0.0029	0.42	12.1	1.4	1	23	388	410	388	410	0.91
12	32	1.8e-07	2.5e-05	25.4	1.1	1	23	416	438	416	438	0.99
13	32	9.4e-07	0.00013	23.1	0.1	1	23	444	466	444	466	0.98
14	32	0.0012	0.18	13.3	2.5	2	23	473	495	472	495	0.95
15	32	1.4e-05	0.002	19.4	6.5	1	23	500	522	500	522	0.97
16	32	2.8e-05	0.004	18.5	1.5	1	23	531	553	531	553	0.98
17	32	7.4e-06	0.0011	20.3	0.9	1	23	559	581	559	581	0.97
18	32	8.2e-05	0.012	17.0	1.3	2	23	588	609	587	609	0.97
19	32	5.5e-06	0.00079	20.7	3.3	1	23	615	637	615	637	0.98
20	32	3.4e-05	0.0049	18.2	0.5	1	23	643	665	643	665	0.96
21	32	0.16	23	6.7	0.8	1	22	757	778	757	780	0.89
22	32	3e-07	4.3e-05	24.7	1.6	2	23	787	808	786	808	0.97
23	32	3.2e-06	0.00045	21.4	3.0	3	23	848	868	846	868	0.95
24	32	0.0002	0.028	15.8	4.6	2	23	874	895	873	895	0.97
25	32	0.00052	0.075	14.5	0.1	1	23	900	922	900	922	0.98
26	32	4.9e-06	0.00071	20.8	2.7	1	23	930	952	930	952	0.98
27	32	0.035	5	8.7	2.5	1	23	958	981	958	981	0.94
28	32	0.00021	0.03	15.7	0.6	2	23	993	1014	992	1014	0.96
29	32	1e-05	0.0015	19.8	2.0	1	23	1020	1042	1020	1042	0.96
30	32	5.3e-08	7.5e-06	27.0	0.2	1	23	1048	1070	1048	1070	0.98
31	32	4.1e-07	5.9e-05	24.2	0.9	1	23	1076	1098	1076	1098	0.98
32	32	0.00063	0.09	14.2	0.9	1	22	1104	1125	1104	1125	0.97

Sequence Information

Coding Sequence: ATGATTCCGCTGTCTCTGcctccagtcccgcaaaaaaagtCGCCGGCGAATTCCAAAGCAGCTACAAAATCtgactcgaaaaaaaccgacGACAAATCTGCGCCCAAGACCGGCAAAAGGTACAAGTGCAAAATTTGCGGCAAGGAGTCGTGGAATTTCCATCAATGGGAGAGACATTATCGCCTGGATCACGGGAAACCCAAGGCGGAAAAATGCTCCCAGTGCGACCGCATTTTCTACGACGACGAGAAGCTCGCGAGACATGTCGTTAAAATGCACCAGGAGGAGCGGCCTTTTCCCTGTCACATCTGCAACAAACCTTTCAAGACCGACAAGTTCCTGAGGATCCACTTGAAGCAACACAACAAACGGTACTCCTGTGAAATCTGCGGGATGTCTAAAGTGTCGCCGTACGACTTGCGTCTGCATATGATGAAGCACAACAAAGAATATTACGCTCACTGCGAGTACTGTCAGCGGGGATTCTACACCAAGCAATCTCTGCAGCGACACATCCTCACGCACACCGGGGAGAGACCTTTTGTATGCAGGATTTGCAATGCCTCGTACGCCAGCGCGTCTTACTTGAGTTTGCACGCGAAAAGCCACACGGAGAGAGAAAAATTCAAGTGCAGCCTCTGCGACTACGAGACTTATTGGAAGACTTCTCTGAAGGGTCACGTCAAAAAACACACCGGAGAGAATCGCATAAAGTGTGAAGTCTGCGGGAAATCTGTTTCCAGTCAGTCGTACCTGCAAGTACACATGAGGATACACACTGGGGAAAAACCAAATATTTGCGAGGTATGCGGCAAGTGTTTCAGTGTCAGGAAGTACCTCATAGTCCACCTCAGAACTCACACGGGGGAGAGACCTTACGAGTGTAAAATATGTCACAAGAGATTTACCCAGCACGGGTCACTCAATTCGCACATGAAGGGCCACAAGGGAGACGTCACGAAAGTCGAAGAAATCGAGGTGATTGAAGAGTTGGAAGAAGAGTATCAAGAATTGTTGTCTTCCTCAAAAATAAAGACGGAACATACGGAGATTTTAAAACGTACCGATCAAAAATCAATTCCAGCCGAAGAATCGTCTGATACAAAAGACAAAGAAACGGAAGTTTCAGTtaaagataaagataaaaataacaaagagTCGTATGTCTGCAAAATATGTAACAAGCACTTCCGGTTAAAGAATCTCTTCGAAGGCCACTTGGTGGCTCACAGTGACGCGCGTCCTTACCAGTGTGACATCTGCAACAAGTCATTCAAACGCACCAGCACCTTGGCCGTGCACCGGAGGATCCACACCCGCGAGCGCAATTTCATCTGCGACGTGTGCGGACGTGCGTTCATCCAGGCCTCGCAATTGGCGATGCACCAGCGCCGGCACTTCGAGAAGTACATCTGCTTCTGCGAGCTCTGTGGCAAGGGATTTTTCACCAACGCCGAATTGCACGGGCACATGAACATCAAACACGGCGCGAAAGAACACGTGTGTCATCACTGCGGCAAATCCTTCCCAAACAATCACACTCTCGCGagacatgcaaacatgcatgACCCGAATTTCAAACCCATTAAACATCAGTGTGAATTCTGCGGGAAAATATTTGCCTACAAAAATTCCCTAATGGTCCACGTCAAGTCGCACACGggggaaaataaatacgacTGTCATCTCTGTGGGAAATCGGTGTCTTCCAGGGGCTCGCTCCAGGATCACTTGCGCCTCCATGGAGGTGAGAAATCTCTGGTCTGCGATGTTTGTGGTAAAGCTTTTCACAAACGGACCACACTGGTGGTACACAAGCGCACGCACACAGGAGAGAAACCCTACAGCTGTGACACTTGCGGAAAATCATTCACTCAGCACTCGACCCTGGTGATACACAAACGTTATCATACAGGTCAGCGTCCGTATCAGTGCACAGTGTGTACCAAGTCGTTTGTGTCAAGAGCGCTGCTCAATGTACACAACAAAGCCCACGTGGTGGTCGTTCAGCCCACaTTCACCCAGACTCGATGCCGCAAAATCTCACCGTATTACTCAATAGCAACAAATGATGAAGATCTAAGACTGACAAATGGTGATCCGGTTCTTGTTCAGATGGATGATGACAAGATACCTGACATTAATCCAGTTTATCCGTCCATTGAGATGTCTCGTAAGTCAGACACTGATGTCCCCCATAAATCAACCATTGATGTGTTGAAAGTTATAGATGAGGATTACGATAACCAAGAGGACATGCCGCTGGCTTATTATTGCAAGCTCTGTGCCAGATTTTTTGCCTCCTCGTTGCTGTTCGAGCAACACAAAGCTGATATGCACGAGAGCAAGCGGAAAAGTACTTGCGACCAGTGCGGTCGGGTTTTTCGTACCCTGGTCAACCTCCGCAAGCATATGAAGAAGCACAGCggacaaaaaagtaaaaaagattACGCTGAGTCGTCAGCGGAGCACTCGGACGTCGATGCCAGTGATAGAGACATCGAGGTCAAGAAAGAAAACAGATCGAGGCGAGAGTTGGCGTGTAAAATTTGTAACAAAGTCTTCCGACACAAGAGTAATTATCAGAAACACCTGGTGAGACACACGACCGGTGACCTGACCTGCAAGCACTGTCCCAAGAAGTTCCGTCTCTATCGTGACTTGACGAGACACGAAAAAACCCATTTCTTGCCGAGCTACATGTGCAAGGAATGCGACTACGAGACTACGGTGCTGGCCGCCCTGACAGTTCACATGCTGAAGCATACAGACAACGCGGGTCTGCCCTACAAGTGCAACGAGTGCGACAAACACTTTAGGAAAGCGACTGATTTACAGGAGCACTACAATATCCATTCCGGCGACAAACCCTTTGTGTGCGAACAGTGCGGAAATTCGTTTTACTTAAGGAGGCAACTGTCGGCCCACTGCCGACGCCTTCACCCTGAAATTAAGGCCAATAAAGTAACCAGCACGACGTGTGATATTTGCGGACGAGTTCTCGCAACAAAGCGCTCGCTCTTCCGGCACAAAGAGAGCCACAATCCAACGAAACTGTATCTGTGCGATTTTTGCGGCAAAAGTTTGAGCAGCGCCGAGCATCTGAAGAAACACAGGCGCATCCACACGGGGGAAAAGCCCTACGTGTGTGATATATGCGGCAAGGGATTCACGGACTCGGAAAATTTACGGATGCACCGGCGCGTCCATACAGGCGAGAAACCCTACAAGTGCGATCAGTGTCCGAAGGCTTTCTCCCAGAGATCAACGCTGACTATTCATCGTCGCGGACACACCGGGGAGAGACCGTACGTGTGTCAAATCTGCCAGAGGGGATTTTCGTGTCAGGGTAATCTCACCGCCCATCAAAAAACCACATGTGTCTAG
Protein Sequence: MIPLSLPPVPQKKSPANSKAATKSDSKKTDDKSAPKTGKRYKCKICGKESWNFHQWERHYRLDHGKPKAEKCSQCDRIFYDDEKLARHVVKMHQEERPFPCHICNKPFKTDKFLRIHLKQHNKRYSCEICGMSKVSPYDLRLHMMKHNKEYYAHCEYCQRGFYTKQSLQRHILTHTGERPFVCRICNASYASASYLSLHAKSHTEREKFKCSLCDYETYWKTSLKGHVKKHTGENRIKCEVCGKSVSSQSYLQVHMRIHTGEKPNICEVCGKCFSVRKYLIVHLRTHTGERPYECKICHKRFTQHGSLNSHMKGHKGDVTKVEEIEVIEELEEEYQELLSSSKIKTEHTEILKRTDQKSIPAEESSDTKDKETEVSVKDKDKNNKESYVCKICNKHFRLKNLFEGHLVAHSDARPYQCDICNKSFKRTSTLAVHRRIHTRERNFICDVCGRAFIQASQLAMHQRRHFEKYICFCELCGKGFFTNAELHGHMNIKHGAKEHVCHHCGKSFPNNHTLARHANMHDPNFKPIKHQCEFCGKIFAYKNSLMVHVKSHTGENKYDCHLCGKSVSSRGSLQDHLRLHGGEKSLVCDVCGKAFHKRTTLVVHKRTHTGEKPYSCDTCGKSFTQHSTLVIHKRYHTGQRPYQCTVCTKSFVSRALLNVHNKAHVVVVQPTFTQTRCRKISPYYSIATNDEDLRLTNGDPVLVQMDDDKIPDINPVYPSIEMSRKSDTDVPHKSTIDVLKVIDEDYDNQEDMPLAYYCKLCARFFASSLLFEQHKADMHESKRKSTCDQCGRVFRTLVNLRKHMKKHSGQKSKKDYAESSAEHSDVDASDRDIEVKKENRSRRELACKICNKVFRHKSNYQKHLVRHTTGDLTCKHCPKKFRLYRDLTRHEKTHFLPSYMCKECDYETTVLAALTVHMLKHTDNAGLPYKCNECDKHFRKATDLQEHYNIHSGDKPFVCEQCGNSFYLRRQLSAHCRRLHPEIKANKVTSTTCDICGRVLATKRSLFRHKESHNPTKLYLCDFCGKSLSSAEHLKKHRRIHTGEKPYVCDICGKGFTDSENLRMHRRVHTGEKPYKCDQCPKAFSQRSTLTIHRRGHTGERPYVCQICQRGFSCQGNLTAHQKTTCV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01005454;
90% Identity: iTF_01004512;
80% Identity: -