Basic Information

Insect: Microplitis manilae
Gene Symbol: zfh1
Assembly: GCA_030273425.1
Location: CP092720.1:1181377-1185802[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 32 0.02 3.1 9.5 2.0 1 23 40 63 40 63 0.96

2 32 0.0074 1.1 10.9 0.4 2 23 70 92 70 92 0.93

3 32 0.00012 0.018 16.5 2.9 1 23 98 120 98 120 0.97

4 32 0.00044 0.069 14.7 0.2 1 23 124 146 124 146 0.98

5 32 4.6e-05 0.0071 17.8 3.0 3 23 154 174 153 174 0.97

6 32 0.00098 0.15 13.6 0.1 1 23 180 202 180 202 0.98

7 32 0.38 59 5.5 1.5 1 23 208 230 208 230 0.97

8 32 2.2e-07 3.4e-05 25.1 0.2 2 23 237 258 236 258 0.97

9 32 3.1e-06 0.00047 21.5 1.1 3 23 266 286 265 286 0.98

10 32 4.5e-06 0.0007 21.0 5.0 1 23 292 314 292 314 0.98

11 32 0.003 0.46 12.1 1.4 1 23 384 406 384 406 0.91

12 32 1.8e-07 2.8e-05 25.4 1.1 1 23 412 434 412 434 0.99

13 32 9.6e-07 0.00015 23.1 0.1 1 23 440 462 440 462 0.98

14 32 0.0013 0.2 13.3 2.5 2 23 469 491 468 491 0.95

15 32 1.4e-05 0.0022 19.4 6.5 1 23 496 518 496 518 0.97

16 32 2.9e-05 0.0044 18.5 1.5 1 23 527 549 527 549 0.98

17 32 7.6e-06 0.0012 20.3 0.9 1 23 555 577 555 577 0.97

18 32 8.4e-05 0.013 17.0 1.3 2 23 584 605 583 605 0.97

19 32 5.7e-06 0.00087 20.7 3.3 1 23 611 633 611 633 0.98

20 32 3.5e-05 0.0054 18.2 0.5 1 23 639 661 639 661 0.96

21 32 0.13 20 6.9 0.5 1 22 753 774 753 776 0.89

22 32 7.9e-07 0.00012 23.4 1.7 2 23 783 804 782 804 0.97

23 32 3.2e-06 0.0005 21.4 3.0 3 23 844 864 842 864 0.95

24 32 0.0002 0.031 15.8 4.6 2 23 870 891 869 891 0.97

25 32 0.00053 0.082 14.5 0.1 1 23 896 918 896 918 0.98

26 32 5e-06 0.00078 20.8 2.7 1 23 926 948 926 948 0.98

27 32 0.036 5.5 8.7 2.5 1 23 954 977 954 977 0.94

28 32 0.00021 0.033 15.7 0.6 2 23 989 1010 988 1010 0.96

29 32 1e-05 0.0016 19.9 2.0 1 23 1016 1038 1016 1038 0.96

30 32 5.4e-08 8.3e-06 27.0 0.2 1 23 1044 1066 1044 1066 0.98

31 32 4.2e-07 6.5e-05 24.2 0.9 1 23 1072 1094 1072 1094 0.98

32 32 0.00065 0.1 14.2 0.9 1 22 1100 1121 1100 1121 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	32	0.02	3.1	9.5	2.0	1	23	40	63	40	63	0.96
2	32	0.0074	1.1	10.9	0.4	2	23	70	92	70	92	0.93
3	32	0.00012	0.018	16.5	2.9	1	23	98	120	98	120	0.97
4	32	0.00044	0.069	14.7	0.2	1	23	124	146	124	146	0.98
5	32	4.6e-05	0.0071	17.8	3.0	3	23	154	174	153	174	0.97
6	32	0.00098	0.15	13.6	0.1	1	23	180	202	180	202	0.98
7	32	0.38	59	5.5	1.5	1	23	208	230	208	230	0.97
8	32	2.2e-07	3.4e-05	25.1	0.2	2	23	237	258	236	258	0.97
9	32	3.1e-06	0.00047	21.5	1.1	3	23	266	286	265	286	0.98
10	32	4.5e-06	0.0007	21.0	5.0	1	23	292	314	292	314	0.98
11	32	0.003	0.46	12.1	1.4	1	23	384	406	384	406	0.91
12	32	1.8e-07	2.8e-05	25.4	1.1	1	23	412	434	412	434	0.99
13	32	9.6e-07	0.00015	23.1	0.1	1	23	440	462	440	462	0.98
14	32	0.0013	0.2	13.3	2.5	2	23	469	491	468	491	0.95
15	32	1.4e-05	0.0022	19.4	6.5	1	23	496	518	496	518	0.97
16	32	2.9e-05	0.0044	18.5	1.5	1	23	527	549	527	549	0.98
17	32	7.6e-06	0.0012	20.3	0.9	1	23	555	577	555	577	0.97
18	32	8.4e-05	0.013	17.0	1.3	2	23	584	605	583	605	0.97
19	32	5.7e-06	0.00087	20.7	3.3	1	23	611	633	611	633	0.98
20	32	3.5e-05	0.0054	18.2	0.5	1	23	639	661	639	661	0.96
21	32	0.13	20	6.9	0.5	1	22	753	774	753	776	0.89
22	32	7.9e-07	0.00012	23.4	1.7	2	23	783	804	782	804	0.97
23	32	3.2e-06	0.0005	21.4	3.0	3	23	844	864	842	864	0.95
24	32	0.0002	0.031	15.8	4.6	2	23	870	891	869	891	0.97
25	32	0.00053	0.082	14.5	0.1	1	23	896	918	896	918	0.98
26	32	5e-06	0.00078	20.8	2.7	1	23	926	948	926	948	0.98
27	32	0.036	5.5	8.7	2.5	1	23	954	977	954	977	0.94
28	32	0.00021	0.033	15.7	0.6	2	23	989	1010	988	1010	0.96
29	32	1e-05	0.0016	19.9	2.0	1	23	1016	1038	1016	1038	0.96
30	32	5.4e-08	8.3e-06	27.0	0.2	1	23	1044	1066	1044	1066	0.98
31	32	4.2e-07	6.5e-05	24.2	0.9	1	23	1072	1094	1072	1094	0.98
32	32	0.00065	0.1	14.2	0.9	1	22	1100	1121	1100	1121	0.97

Sequence Information

Coding Sequence: ATGATACCACTGTCTCTGCCTCCAGTGACACAAAAAAAGCCAGCGAATTCCAAAGCAGCTAAAAAATCagactcgaaaaaaaccgACGACAAATCCGCGCCCAAAACCGGCAAAAGGTACAAGTGCAAAATTTGCGGCAAGGAGTCGTGGAATTTCCATCAATGGGAGAGACATTATCGACTGGATCACGGGAAACCCAAGGCGGAAAAATGCTCCCAGTGCGACCGCATTTTCTACGACGACGAAAAGCTCGCGAGACATGTCGTTAAAATGCACCAGGAGGAGCGGCCTTTTCCCTGTCACATCTGCAACAAACCTTTCAAGACCGATAAGTTCCTGAGGATCCACTTGAAGCAGCACAACAAACGGTACTCCTGTGAAATTTGCGGGATGTCTAAAGTGTCGCCGTACGACTTGCGTCTGCACATGATGAAACACAACAAAGAATATTACGCTCACTGCGAGTACTGTCAGCGGGGATTCTACACCAAGCAATCTCTGCAGCGACACATCCTCACGCACACCGGGGAGAGACCTTTTGTGTGCAGGATTTGCAACGCCTCGTACGCCAGCGCGTCTTACTTGAGTTTGCACGCGAAAAGCCACTCGGAGAGAGAAAAATTCAAGTGCAGCCTCTGCGACTACGAGACTTATTGGAAGACTTCTCTGAAGGGTCACGTCAAAAAACACACCGGGGAGAATCGGATTAAATGTGAAGTCTGCGGGAAATCTGTTTCCAGTCAGTCGTACTTGCAAGTACACATGAGGATACACACTGGAGAAAAACCAAATATTTGCGAGGTGTGCGGCAAGTGTTTCAGTGTCAGGAAGTATCTCATAGTCCACCTCAGGACTCACACGGGGGAGAGGCCGTACGAGTGTAAAATATGTCACAAGAGATTCACCCAGCACGGGTCACTCAATTCGCACATGAAGGGCCACAAGGGAGACGTCGCGAAAGTCGAAGAAGTCGAGGATATTGAACAGTTGGAAGAAGAATTGTTGTCTTCCTCGCAAATAAAGACGGAACATACGGAGATTTTAAAACGTACCGATCAAAAATCAATTCCAGCCGAAGAACCGTCTGATACAAAAGACAAAGAGACGGAAGTCTCagttaaagataaaaatagaaataataaagaGTCATATGTCTGCAAAATATGTAACAAGCACTTCCGGTTAAAGAATCTGTTCGAAGGCCACTTGGTGGCTCACAGCGACGCGCGTCCTTACCAGTGTGACATCTGCAACAAGTCATTCAAACGCACCAGCACTTTGGCCGTGCACCGGAGGATCCACACCCGCGAGCGCAATTTCATCTGCGACGTGTGCGGACGTGCGTTCATCCAAGCCTCGCAACTAGCGATGCACCAGCGCCGGCACTTTGAGAAGTACATCTGCTTCTGCGAGCTCTGTGGCAAGGGATTTTTCACCAACGCCGAATTGCACGGGCACATGAACATCAAACACGGCGCGAAAGAACACGTGTGTCATCACTGCGGCAAGTCCTTCCCAAACAATCACACTCTCGCGAGACATGCAAACATGCATGACCCGAATTTCAAACCCATTAAACATCAGTGTGAATTCTGCGGTAAAATATTTGCCTACAAAAATTCCCTAATGGTCCATGTCAAGTCACACACGGGGGAAAATAAATACGACTGTCATCTCTGTGGGAAATCAGTATCTTCCAGGGGCTCGCTCCAGGACCACTTGCGCCTCCATGGAGGTGAGAAATCTCTGGTCTGCGATGTTTGTGGTAAAGCTTTTCACAAAAGGACCACACTGGTGGTACACAAGCGCACGCATACAGGAGAGAAACCCTACAGCTGTGACACTTGCGGGAAATCATTCACTCAGCACTCGACCCTGGTGATACACAAACGTTATCATACAGGTCAGCGTCCGTATCAGTGCACAGTGTGTACCAAGTCCTTTGTGTCAAGAGCGCTGCTTAATGTACACAACAAAGCCCACGTGGTGGTCGTTCAGCCCACATTCACCCAGACTCGATGCAGCAAAATCTCACCGTATTACTCGATAGCAACAAATGATGAAGATCTAAGACTGACAAATGGTGATCCGGTTGTTGTTCAGATGGATGATGACAAGATACCTGACATTAATCCAGTTTATCCGTCCATTGAGATGTCTCGTAAGTCAGACACTGATGTGTCCCATAAATCAGGCATTGATGTGTTGAAAGTTATAGATGAGGATCACGATAACCAAGAGGACATGCCGCTGGCTTATTACTGCAAGCTCTGTGCCAGATTTTTTGCCTCGCCGTTGCTGTTCGAGCAACACAAAGCTGATATGCACGAGAGCAAGCGGAAAAGTACTTGCGACCAGTGCGGTCGGGTTTTTCGTACGATGGTTAACCTCCGCAAGCATATGAAGAAGCACAGCggacaaaaaagtaaaaaagattgcGCTGAGTCGTCAGCGGAGCACTCGGACGTCGATGCCAGTGATAGAGACATCGAGGTCAAGAAAGAAAATAGATCGAGGCGAGAGTTGGCGTGTAAAATATGTAACAAAGTCTTCCGACACAAGAGTAATTATCAGAAACACCTGGTGAGACACACGACCGGTGACCTGACCTGCAAGCACTGTCCCAAGAAGTTCCGTCTCTATCGCGACTTGACGAGACACGAAAAAACCCATTTCTTGCCGAGCTACATGTGCAAGGAATGCGACTACGAGACCACAGTGCTGGCCGCCCTGACAGTTCACATGCTGAAGCACACGGACAACGCGGGTCTGCCCTACAAGTGCAACGAGTGCGACAAACACTTTAGGAAAGCGACTGATTTGCAGGAGCACTACAATATTCATTCCGGCGACAAGCCTTTTGTGTGCGAGCAGTGCGGGAATTCGTTTTACTTAAGGAGGCAACTGTCGGCCCACTGCCGACGCCTTCACCCAGAAATTAAGGCCAATAAAGTAACCAGCACGACGTGTGATATTTGCGGACGAGTTCTCGCAACAAAGCGCTCGCTCTTCCGGCATAAAGAGAGCCACAATCCGACGAAACTGTATCTGTGCGATTTTTGCGGGAAAAGTTTGAGCAGCGCTGAGCATCTGAAGAAACACAGGCGCATCCACACTGGGGAAAAGCCCTACGTGTGTGATATATGCGGCAAGGGATTCACGGACTCGGAAAATTTACGGATGCACCGACGCGTCCATACGGGCGAGAAACCCTACAAGTGCGATCAGTGCCCGAAGGCTTTTTCCCAGAGATCAACGCTGACTATCCATCGTCGCGGACACACTGGGGAGAGACCGTACGTGTGTCAAATCTGCCAGAGGGGATTTTCGTGTCAGGGTAATCTCACCGCCCATCAAAAAACCACATGTGTCTAG
Protein Sequence: MIPLSLPPVTQKKPANSKAAKKSDSKKTDDKSAPKTGKRYKCKICGKESWNFHQWERHYRLDHGKPKAEKCSQCDRIFYDDEKLARHVVKMHQEERPFPCHICNKPFKTDKFLRIHLKQHNKRYSCEICGMSKVSPYDLRLHMMKHNKEYYAHCEYCQRGFYTKQSLQRHILTHTGERPFVCRICNASYASASYLSLHAKSHSEREKFKCSLCDYETYWKTSLKGHVKKHTGENRIKCEVCGKSVSSQSYLQVHMRIHTGEKPNICEVCGKCFSVRKYLIVHLRTHTGERPYECKICHKRFTQHGSLNSHMKGHKGDVAKVEEVEDIEQLEEELLSSSQIKTEHTEILKRTDQKSIPAEEPSDTKDKETEVSVKDKNRNNKESYVCKICNKHFRLKNLFEGHLVAHSDARPYQCDICNKSFKRTSTLAVHRRIHTRERNFICDVCGRAFIQASQLAMHQRRHFEKYICFCELCGKGFFTNAELHGHMNIKHGAKEHVCHHCGKSFPNNHTLARHANMHDPNFKPIKHQCEFCGKIFAYKNSLMVHVKSHTGENKYDCHLCGKSVSSRGSLQDHLRLHGGEKSLVCDVCGKAFHKRTTLVVHKRTHTGEKPYSCDTCGKSFTQHSTLVIHKRYHTGQRPYQCTVCTKSFVSRALLNVHNKAHVVVVQPTFTQTRCSKISPYYSIATNDEDLRLTNGDPVVVQMDDDKIPDINPVYPSIEMSRKSDTDVSHKSGIDVLKVIDEDHDNQEDMPLAYYCKLCARFFASPLLFEQHKADMHESKRKSTCDQCGRVFRTMVNLRKHMKKHSGQKSKKDCAESSAEHSDVDASDRDIEVKKENRSRRELACKICNKVFRHKSNYQKHLVRHTTGDLTCKHCPKKFRLYRDLTRHEKTHFLPSYMCKECDYETTVLAALTVHMLKHTDNAGLPYKCNECDKHFRKATDLQEHYNIHSGDKPFVCEQCGNSFYLRRQLSAHCRRLHPEIKANKVTSTTCDICGRVLATKRSLFRHKESHNPTKLYLCDFCGKSLSSAEHLKKHRRIHTGEKPYVCDICGKGFTDSENLRMHRRVHTGEKPYKCDQCPKAFSQRSTLTIHRRGHTGERPYVCQICQRGFSCQGNLTAHQKTTCV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01006474; iTF_01004512;
90% Identity: iTF_01004512;
80% Identity: -