Mmed016901.1
Basic Information
- Insect
- Microplitis mediator
- Gene Symbol
- -
- Assembly
- GCA_029852145.1
- Location
- CM056850.1:18129014-18136481[+]
Transcription Factor Domain
- TF Family
- MBD
- Domain
- MBD domain
- PFAM
- PF01429
- TF Group
- Unclassified Structure
- Description
- The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 4.8e-13 2.8e-09 37.4 0.2 5 72 309 373 306 376 0.86 2 2 3.7 2.2e+04 -3.9 0.1 16 26 628 638 628 639 0.90
Sequence Information
- Coding Sequence
- ATGGATGTCGTGGCTACCGATGTAAATGGCGGGAACGCTGAAGTGGCGCGCGACGACGATGTGCCAGATCCAGGAGTTGTTCAGCTCACTAAATCACCAAAAGTTGATGAGGATAAAGACACCAAGGACAAGGATATCAAAGACGTAAAAGAGAACAAAGATAAGGATGCCGAGATGGAAGAGGATAAAAAAGATGTGAAAGTGGAAGAGGTTCAGAAAAAAGAAGAACAAGAGACGATTGTAGTTAATGAGACTGAAAAAATTGACGAGCAAGAGGTTAATGGTGATGTAAAGGGTGTTAGTGTTtctgttgttaaaaaaaatatgacaccTGTGGGTAAACGAAAATTACGTAAAACTAAAGCTAATTCTACTAGTGCTGTCGAGAGTGAACACCAGGATTCACCCTCAGTAAATGCAAATGCTAATGCTAATGCTAATTCTAATAATAGCAGAACACGGAATCAAAAGAGAAAATTATCAGAACCTGATAATCATACATCAGATGATTCAATGGATTTTATAGGTTTTGATAGCAATAGTTTGATGAAAGTTAACCCTGCTACGgaaattttgttgaaattGATCGCCGAAGCTGAGGCAGAGATTTCATCATCACAACCATCTGCTAAACGCCCTAAGCGTTCGCTGTCCAAGGGTCCAGTTCGTAGGAATGTTGAACTAAAAACAGATGATCATCAAGcagAAGTAGCAAAAGGTAAAAAGAAATTGGAGAAACCGGACGGTGAGGTCGACAGTGGGAATGCTGCTCCTGTAACTGCTGCGGTTAAAAATGACGCTGGAAAATCACCACCGTCTGCTAAAACTCCAGTTGTGAGTAGACGGGGAATGAGAAATTCTCATGCACCACAAACTTCTAGTGTTGCTGCAGCGAAACAAAAAGTTTCGGCTGATGTGACTAATCCAGAATACAAGGAACCTTTCAAGTATGGATGGAAACGCGAACTTGTGTATAAAACCGAGACTGATTCAACGAAAAAAGTTGTTGAAGTTTCTTATTACACACCAAAGGGTAAAAAAGTTAAGAGTCTCAGAGAAATTGCCGAATTCCtgaataCAAAAGAATTGAcggtagataattttatatttaccaAAGAACCAACGGGTATTAACGATCCGCAATATGAAATAATCAAAGACGAAGCAACTCCCATCAGTACTCCAGTTAGTGCGGGACCCGCCAAGAAAATAGGAACTGGCAAGAAAGCTGCCGCTACAAAAAGACTTACTGGAAAAATATCTCCTACACCAGCTAAAACTCTTGGGAAAAATTTACCTCTGAAAACAAGTACGCCCGGGATTAAAGTTAAAGTTCCCGTCAAAAGAGGTTCACTAAGAAAAGACGTATCACCGCCCAAAGAAACTGACGTGCTCGGGTGGACCAACTCGTCAAACATCACAAGACGCAGTCAAGCTGCCACGGAAAAAACGTCGCCTTACAAATCAAAGAGGTCATTGAaGACCAAACTCCAGGAACCCTGCAGTATCCGGTGTTCTATGAGCATGGGTCTGATACCGAGTCTTCAATGCTGTGTCTGCCTCTGTCTGTATCATCCTGAATGCGTAGGTCACGCTGAGAATTCCACCAGTGAAGATTACGTTTGCaagaattgtCGGCACGACAATGAGGAAGGTAAGAAAGTTTCTATAACACCACCGCCATTGATACCAATAAGTATGATCGGTACACAAAATGCAAAATCACTTTTCCCGCCAATTGATCGACAATCACCGCCGCGAGTTTTATCAAGAAATTCAAAACCTGACAGTGAatattattcgaaaaattcagCAAAATCACATCGAGATTCATTGTCATCAACTGGtggcaataaattaaataccgCGGCTTGGTATTCAAGAAGAGATTTTATGCAGAGACAAGACGGCTCGGAGCCTAAACCAGCACAAAATATCGCGCTATTAGCTGGCAAAAGATATATTGTCGTACCGAAAAATAACGCTGGTTCAGTTCAGCCGGCAATCAGGCCCAATAAAAcccaaaataaattatcaattgatgacgttgataaaataaattattctagAGAAATAGGATTCAAAGAGTCTAGAGCGCCGAAAAAATTACCAACTAGACTTTCAAGTGAAGAgatttttaaagataaaaataatgaaaagagTCAAGACTCAAAGACAGCAACGATAGACGTTGAAGAACCGCAGAGACAAAATTCCGATTTGAGTGACAAGACAGATGACACTTGCATTAGTGAAACTCCTGTAGGCGCTTTagaaaaaattcacaaaacaCTTGAAGACCAAGTGGAGGATGACGCGCTGGTACAAGAAGTTAAAGATAACGATCAAGCGCAAGAACAGGAAAATTTACACGACGATATTGAGGAAAATGTACCAGCTACTGTTggaagaaaaacaaatttaggTAAAGAGATTAGTAATGAAAAATCAAATGAAGAAAAAGCCATTGAAAGATCAGAGTCCATGGATACCGATGGCTCGAGCGCATCTGATGAAATGCCGATTAAAGAATCGGAATTTGATGCTGTAGCTGCAACTGCTGTACCAAAAGATATTTTAGAATCAGAGGCATCTGAGCTAACAACGAGTCCAGTGAAACAGACGGCGGGTAATTTAAATGaggaaaaaaatcaacaagTTGGAactaatgataaaaaagaGGTGGAGGCAGATAAaaaGAAAGCTGTGGCGCCGCTGGTTGAAGTCGATCAGAGACAGTACTTTATGTCGACAGTCTGCTCTGGTTACAATGCACTGTCACGAGTTTTCCAGTATCTTAAAGTACAAGAATTATTACGCGCAGCGCGTGTGTGTAAAATGTGGCGCGATTTAGCTGCACATCCCGCGCTGTGGAAGACAGTCCGTATGAAGAATAGTCAGGTCACCGATTGGGACGGATTGGTAGCAACCCTACAGAGGCACGGGACTGAACATCTCGACTTACGTAAAATGCTGATTGCCCCTGAATCTGACAgtatttggcaaaaatttgTATCAGTTATTCCCAATGTCAAGACTCTTATCAAACTCGAACTGTGTCGCTGTCCCGTGATGGTTGTTGAGGAAGTAATTAAAGTTTGTCCGCAATTGCAAGTACTCAGTGCCATGTCAATAAAATGTGATTGGCTCAATTTAGAGGATATCGGTAACTTAAAATCTTGTGAAGAATTAAGACTTAAAGCCATCACTGGTATGTCATTACACGGTGATTTAACGCCACTACAAAATCTCACTCAGCTGTCACACTTGAGTCTAACGTCAGTTAAAGaacttggtaaaaaaaaaatagaaatactGGCGTCACTTGTTAATCTCGAGTCACTTGAGTTGGGCGAGTGCTCGGATTTTTCATCAAAGTTTGGCACTGCGGTGTTGTGTAAACTCACAAAACTCGAACGATTGAGACTTGAAAAGGGTCAAGGTACTTGCTGTACCTTCGATATACTTAAAGGTGTTGCTAAACTCGATAAATTACATCAATTGGAACTGGTTAACTTTGATGTTAAGAATGGCTTTGATAAACATCTGgcaaattgtaaaaatattaagaggCTGCTTATTATTCCGACGTACATTTCACAGTCAGCGACGTCAAATAATATGGTATTGGGTGGTGTCACTGAGTTATCTGACAGTCTCACGTATTTCGTCTGGGGTGTAACACTAGAATTGTTAAGAGTTACTCAATTATTTGTCGACCAATGTAATCAAATGAATAAACAAGTGTCTGGTGATTCGATACCTGTATTGAAACCAGTACCTTGTTTGAAACTTATTGAGGATGCTGATGACACGAAGATGTCACCCAAagCTGAAGAAAAGTCAACAAATTCATCAAATCCTCAAGTAGACATTTTACCTTTACCACAGTTGCAAAAACTTCTCTTGACAGCATTACCGAAAACAcgagtgaaaatattaatgataccTTTCCAAGCTACCTGGAGACAAAGTATTTCAGACACTGCGTCACAgtaa
- Protein Sequence
- MDVVATDVNGGNAEVARDDDVPDPGVVQLTKSPKVDEDKDTKDKDIKDVKENKDKDAEMEEDKKDVKVEEVQKKEEQETIVVNETEKIDEQEVNGDVKGVSVSVVKKNMTPVGKRKLRKTKANSTSAVESEHQDSPSVNANANANANSNNSRTRNQKRKLSEPDNHTSDDSMDFIGFDSNSLMKVNPATEILLKLIAEAEAEISSSQPSAKRPKRSLSKGPVRRNVELKTDDHQAEVAKGKKKLEKPDGEVDSGNAAPVTAAVKNDAGKSPPSAKTPVVSRRGMRNSHAPQTSSVAAAKQKVSADVTNPEYKEPFKYGWKRELVYKTETDSTKKVVEVSYYTPKGKKVKSLREIAEFLNTKELTVDNFIFTKEPTGINDPQYEIIKDEATPISTPVSAGPAKKIGTGKKAAATKRLTGKISPTPAKTLGKNLPLKTSTPGIKVKVPVKRGSLRKDVSPPKETDVLGWTNSSNITRRSQAATEKTSPYKSKRSLKTKLQEPCSIRCSMSMGLIPSLQCCVCLCLYHPECVGHAENSTSEDYVCKNCRHDNEEGKKVSITPPPLIPISMIGTQNAKSLFPPIDRQSPPRVLSRNSKPDSEYYSKNSAKSHRDSLSSTGGNKLNTAAWYSRRDFMQRQDGSEPKPAQNIALLAGKRYIVVPKNNAGSVQPAIRPNKTQNKLSIDDVDKINYSREIGFKESRAPKKLPTRLSSEEIFKDKNNEKSQDSKTATIDVEEPQRQNSDLSDKTDDTCISETPVGALEKIHKTLEDQVEDDALVQEVKDNDQAQEQENLHDDIEENVPATVGRKTNLGKEISNEKSNEEKAIERSESMDTDGSSASDEMPIKESEFDAVAATAVPKDILESEASELTTSPVKQTAGNLNEEKNQQVGTNDKKEVEADKKKAVAPLVEVDQRQYFMSTVCSGYNALSRVFQYLKVQELLRAARVCKMWRDLAAHPALWKTVRMKNSQVTDWDGLVATLQRHGTEHLDLRKMLIAPESDSIWQKFVSVIPNVKTLIKLELCRCPVMVVEEVIKVCPQLQVLSAMSIKCDWLNLEDIGNLKSCEELRLKAITGMSLHGDLTPLQNLTQLSHLSLTSVKELGKKKIEILASLVNLESLELGECSDFSSKFGTAVLCKLTKLERLRLEKGQGTCCTFDILKGVAKLDKLHQLELVNFDVKNGFDKHLANCKNIKRLLIIPTYISQSATSNNMVLGGVTELSDSLTYFVWGVTLELLRVTQLFVDQCNQMNKQVSGDSIPVLKPVPCLKLIEDADDTKMSPKAEEKSTNSSNPQVDILPLPQLQKLLLTALPKTRVKILMIPFQATWRQSISDTASQ
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01004250;
- 90% Identity
- iTF_01003526;
- 80% Identity
- -